ECSP11011081A - 3-aminociclopentancarboxamidas - Google Patents

3-aminociclopentancarboxamidas

Info

Publication number
ECSP11011081A
ECSP11011081A EC2011011081A ECSP11011081A ECSP11011081A EC SP11011081 A ECSP11011081 A EC SP11011081A EC 2011011081 A EC2011011081 A EC 2011011081A EC SP11011081 A ECSP11011081 A EC SP11011081A EC SP11011081 A ECSP11011081 A EC SP11011081A
Authority
EC
Ecuador
Prior art keywords
aminociclopentancarboxamidas
compound
formula
pharmaceutically acceptable
acceptable salt
Prior art date
Application number
EC2011011081A
Other languages
English (en)
Spanish (es)
Inventor
Rajes Devraj
Robert Hughes
Steven Ronald Turner
Wei Huang
Donald Joseph Rogier Jr
John Isidro Trujillo
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of ECSP11011081A publication Critical patent/ECSP11011081A/es

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
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    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • A61P29/02—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID] without antiinflammatory effect
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    • A61P3/02—Nutrients, e.g. vitamins, minerals
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    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
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    • A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
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  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
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  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
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EC2011011081A 2008-11-26 2011-05-25 3-aminociclopentancarboxamidas ECSP11011081A (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11805308P 2008-11-26 2008-11-26

Publications (1)

Publication Number Publication Date
ECSP11011081A true ECSP11011081A (es) 2011-12-30

Family

ID=41693100

Family Applications (1)

Application Number Title Priority Date Filing Date
EC2011011081A ECSP11011081A (es) 2008-11-26 2011-05-25 3-aminociclopentancarboxamidas

Country Status (38)

Country Link
US (2) US8293903B2 (enExample)
EP (1) EP2370442B9 (enExample)
JP (1) JP5108153B2 (enExample)
KR (1) KR101374412B1 (enExample)
CN (1) CN102227429B (enExample)
AP (1) AP3113A (enExample)
AU (1) AU2009321221B2 (enExample)
BR (1) BRPI0920936A2 (enExample)
CA (1) CA2743030C (enExample)
CL (1) CL2011001223A1 (enExample)
CO (1) CO6361921A2 (enExample)
CR (1) CR20110275A (enExample)
CU (1) CU24022B1 (enExample)
CY (1) CY1114020T1 (enExample)
DK (1) DK2370442T5 (enExample)
DO (1) DOP2011000154A (enExample)
EA (1) EA020470B1 (enExample)
EC (1) ECSP11011081A (enExample)
ES (1) ES2415430T3 (enExample)
GE (1) GEP20146064B (enExample)
HR (1) HRP20130409T2 (enExample)
IL (1) IL212732A (enExample)
MA (1) MA32834B1 (enExample)
ME (1) ME01144B (enExample)
MX (1) MX2011005526A (enExample)
MY (1) MY152557A (enExample)
NI (1) NI201100102A (enExample)
NZ (1) NZ592919A (enExample)
PE (1) PE20110831A1 (enExample)
PL (1) PL2370442T3 (enExample)
PT (1) PT2370442E (enExample)
RS (2) RS52810B9 (enExample)
SI (1) SI2370442T1 (enExample)
SV (1) SV2011003923A (enExample)
TN (1) TN2011000254A1 (enExample)
UA (1) UA99978C2 (enExample)
WO (1) WO2010061329A1 (enExample)
ZA (1) ZA201104069B (enExample)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2370442B9 (en) * 2008-11-26 2013-09-04 Pfizer Inc. 3-Aminocyclopentanecarboxamides as chemokine receptor modulators
KR101303963B1 (ko) * 2011-04-08 2013-09-05 재단법인 경기과학기술진흥원 (1ｒ,2ｒ,3ｒ)-3-아미노사이클로펜탄-1,2-디올을 포함하는 항알러지용 조성물
AU2015240465B2 (en) 2014-04-04 2020-02-27 Del Mar Pharmaceuticals Use of dianhydrogalactitol and analogs or derivatives thereof to treat non-small-cell carcinoma of the lung and ovarian cancer
TW201605451A (zh) * 2014-07-17 2016-02-16 參天製藥股份有限公司 老年性黃斑部病變之預防或治療劑
JOP20190040A1 (ar) * 2016-09-14 2019-03-10 Novartis Ag توليفة من ناهضات fxr
TWI830733B (zh) * 2018-05-11 2024-02-01 中國大陸商迪哲（江蘇）醫藥有限公司 環戊烷化合物

Family Cites Families (28)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU693143B2 (en) 1993-12-06 1998-06-25 Cytel Corporation CS-1 peptidomimetics, compositions and methods of using the same
US5510332A (en) 1994-07-07 1996-04-23 Texas Biotechnology Corporation Process to inhibit binding of the integrin α4 62 1 to VCAM-1 or fibronectin and linear peptides therefor
AU2964295A (en) 1994-07-11 1996-02-09 Athena Neurosciences, Inc. Inhibitors of leukocyte adhesion
US5462208A (en) 1994-08-01 1995-10-31 The Procter & Gamble Company Two-phase dispensing systems utilizing bellows pumps
US5811391A (en) 1994-08-25 1998-09-22 Cytel Corporation Cyclic CS-1 peptidomimetics, compositions and methods of using same
GB9524630D0 (en) 1994-12-24 1996-01-31 Zeneca Ltd Chemical compounds
US6306840B1 (en) 1995-01-23 2001-10-23 Biogen, Inc. Cell adhesion inhibitors
WO1996031206A2 (en) 1995-04-07 1996-10-10 Warner-Lambert Company Flavones and coumarins as agents for the treatment of atherosclerosis
US5704960A (en) 1995-12-20 1998-01-06 Corning, Inc. Method of forming an optical fiber for reduced polarization effects in amplifiers
GB9603741D0 (en) 1996-02-22 1996-04-24 Lin Mei Treatment of water by electrolysis
JP2000516210A (ja) 1996-07-12 2000-12-05 ロイコサイト，インコーポレーテッド ケモカインレセプターアンタゴニストとその使用方法
WO1998042656A1 (en) 1997-03-21 1998-10-01 Cytel Corporation Novel compounds
ES2257808T3 (es) 1997-05-29 2006-08-01 MERCK & CO., INC. (A NEW JERSEY CORP.) Acidos biarilalcanoicos como inhibidores de adhesion celular.
AU728435B2 (en) 1997-05-29 2001-01-11 Merck & Co., Inc. Sulfonamides as cell adhesion inhibitors
CA2291778A1 (en) 1997-05-29 1998-12-03 Merck & Co., Inc. Heterocyclic amide compounds as cell adhesion inhibitors
ATE256699T1 (de) 1997-05-30 2004-01-15 Celltech Therapeutics Ltd Entzündungshemmende tyrosin-derivate
PT991619E (pt) 1997-06-23 2004-02-27 Upjohn Co Inibidores da adesao celular mediada pela alfa4beta1
US6312689B1 (en) 1998-07-23 2001-11-06 Millennium Pharmaceuticals, Inc. Anti-CCR2 antibodies and methods of use therefor
JO2479B1 (en) 2002-04-29 2009-01-20 ميرك شارب اند دوم ليمتد Rates for the activity of the chemokine receptor of tetrahydrobranyl cycloneptil tetrahydrobredo predine
DK1501507T3 (da) * 2002-04-29 2008-09-29 Merck & Co Inc Tetrahydropyranyl-cyclopentyl-tertrahydropyridopyrindin-modulatorer af kemokin-receptor-aktivitet
GEP20084505B (en) 2003-12-18 2008-10-10 Incyte Corp 3-cycloalkylaminopyrrolidine derivatives as modulators of chemokine receptors
AU2005219438B2 (en) * 2004-03-03 2011-02-17 Chemocentryx, Inc. Bicyclic and bridged nitrogen heterocycles
JP2007534755A (ja) 2004-04-28 2007-11-29 メルク　エンド　カムパニー　インコーポレーテッド ケモカイン受容体活性のモジュレーターとなる３，３−ジ置換テトラヒドロピラニルシクロペンチルアミド
EP1763347A4 (en) * 2004-06-28 2009-05-20 Incyte Corp 3-AMINOCYCLOPENTANECARBOXAMIDES AS MODULATORS OF CHEMOKINE RECEPTORS
CN1976707A (zh) * 2004-06-28 2007-06-06 因赛特公司 作为趋化因子受体调节剂的3－氨基环戊烷甲酰胺类
AP2006003849A0 (en) 2004-06-28 2006-12-31 Incyte Corp 3-Aminocyclopentanecarboxamides as modulators of chemokine receptors
MEP1008A (xx) 2005-12-21 2010-02-10 Incyte Corp 3-aminociklopentankarboksamidi kao modulatori receptora hemokina
EP2370442B9 (en) * 2008-11-26 2013-09-04 Pfizer Inc. 3-Aminocyclopentanecarboxamides as chemokine receptor modulators

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ES2415430T9 (es) 2013-11-25
MY152557A (en) 2014-10-31
RS52810B (en) 2013-10-31
WO2010061329A1 (en) 2010-06-03
MX2011005526A (es) 2011-06-06
HRP20130409T1 (en) 2013-06-30
NI201100102A (es) 2011-09-27
KR101374412B1 (ko) 2014-03-17
HK1161261A1 (en) 2012-08-24
SI2370442T1 (sl) 2013-06-28
IL212732A0 (en) 2011-07-31
US20130197008A1 (en) 2013-08-01
DK2370442T5 (da) 2013-09-23
AU2009321221A1 (en) 2010-06-03
PT2370442E (pt) 2013-06-27
AP2011005732A0 (en) 2011-06-30
JP2012509931A (ja) 2012-04-26
JP5108153B2 (ja) 2012-12-26
ES2415430T3 (es) 2013-07-25
CN102227429A (zh) 2011-10-26
RS52810B8 (sr) 2019-08-30
NZ592919A (en) 2013-05-31
EP2370442A1 (en) 2011-10-05
US8946413B2 (en) 2015-02-03
US8293903B2 (en) 2012-10-23
ME01144B (me) 2013-03-20
DK2370442T3 (da) 2013-06-17
EP2370442B9 (en) 2013-09-04
EA020470B1 (ru) 2014-11-28
CU24022B1 (es) 2014-07-30
CN102227429B (zh) 2014-05-28
PL2370442T3 (pl) 2013-08-30
US20110144129A1 (en) 2011-06-16
CU20110121A7 (es) 2013-05-31
SV2011003923A (es) 2011-07-28
TN2011000254A1 (fr) 2012-12-17
CO6361921A2 (es) 2012-01-20
PE20110831A1 (es) 2011-11-20
UA99978C2 (en) 2012-10-25
CR20110275A (es) 2011-07-01
AP3113A (en) 2015-01-31
GEP20146064B (en) 2014-03-25
CA2743030A1 (en) 2010-06-03
CY1114020T1 (el) 2016-07-27
IL212732A (en) 2016-06-30
KR20110075036A (ko) 2011-07-05
DOP2011000154A (es) 2011-07-31
CA2743030C (en) 2013-10-22
CL2011001223A1 (es) 2011-09-02
RS52810B9 (sr) 2019-06-28
MA32834B1 (fr) 2011-11-01
ZA201104069B (en) 2012-02-29
AU2009321221B2 (en) 2013-04-04
EA201170721A1 (ru) 2011-12-30
EP2370442B1 (en) 2013-04-24
BRPI0920936A2 (pt) 2020-08-11
HRP20130409T2 (hr) 2013-11-22

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