JP5108153B2 - ケモカイン受容体モジュレーターとしての３−アミノシクロペンタンカルボキサミド - Google Patents

ケモカイン受容体モジュレーターとしての３−アミノシクロペンタンカルボキサミド Download PDF

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JP5108153B2
JP5108153B2 JP2011538083A JP2011538083A JP5108153B2 JP 5108153 B2 JP5108153 B2 JP 5108153B2 JP 2011538083 A JP2011538083 A JP 2011538083A JP 2011538083 A JP2011538083 A JP 2011538083A JP 5108153 B2 JP5108153 B2 JP 5108153B2
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amino
methyl
carbonyl
diazabicyclo
anhydro
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JP2012509931A5 (enExample
JP2012509931A (ja
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ヴェンカテスワラン デヴラジュ ラジェシュ
ファング ウェイ
オーウェン ヒューズ ロバート
ジョセフ ロジェ ジュニア． ドナルド
イシドゥロ トルヒーヨ ジョン
ロナルド ターナー スティーヴ
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ファイザー・インク
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
    • A—HUMAN NECESSITIES
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    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

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  • General Health & Medical Sciences (AREA)
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  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Diabetes (AREA)
  • Immunology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Pulmonology (AREA)
  • Dermatology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Hematology (AREA)
  • Endocrinology (AREA)
  • Obesity (AREA)
  • Communicable Diseases (AREA)
  • Urology & Nephrology (AREA)
  • Oncology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Virology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Ophthalmology & Optometry (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Vascular Medicine (AREA)
  • Reproductive Health (AREA)
JP2011538083A 2008-11-26 2009-11-20 ケモカイン受容体モジュレーターとしての３−アミノシクロペンタンカルボキサミド Active JP5108153B2 (ja)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US11805308P 2008-11-26 2008-11-26
US61/118,053 2008-11-26
PCT/IB2009/055232 WO2010061329A1 (en) 2008-11-26 2009-11-20 3-aminocyclopentanecarboxamides as chemokine receptor modulators

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JP2012509931A JP2012509931A (ja) 2012-04-26
JP2012509931A5 JP2012509931A5 (enExample) 2012-08-09
JP5108153B2 true JP5108153B2 (ja) 2012-12-26

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US (2) US8293903B2 (enExample)
EP (1) EP2370442B9 (enExample)
JP (1) JP5108153B2 (enExample)
KR (1) KR101374412B1 (enExample)
CN (1) CN102227429B (enExample)
AP (1) AP3113A (enExample)
AU (1) AU2009321221B2 (enExample)
BR (1) BRPI0920936A2 (enExample)
CA (1) CA2743030C (enExample)
CL (1) CL2011001223A1 (enExample)
CO (1) CO6361921A2 (enExample)
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CY (1) CY1114020T1 (enExample)
DK (1) DK2370442T5 (enExample)
DO (1) DOP2011000154A (enExample)
EA (1) EA020470B1 (enExample)
EC (1) ECSP11011081A (enExample)
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GE (1) GEP20146064B (enExample)
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NI (1) NI201100102A (enExample)
NZ (1) NZ592919A (enExample)
PE (1) PE20110831A1 (enExample)
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PT (1) PT2370442E (enExample)
RS (2) RS52810B9 (enExample)
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JOP20190040A1 (ar) * 2016-09-14 2019-03-10 Novartis Ag توليفة من ناهضات fxr
TWI830733B (zh) * 2018-05-11 2024-02-01 中國大陸商迪哲（江蘇）醫藥有限公司 環戊烷化合物

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ES2415430T9 (es) 2013-11-25
MY152557A (en) 2014-10-31
RS52810B (en) 2013-10-31
WO2010061329A1 (en) 2010-06-03
MX2011005526A (es) 2011-06-06
HRP20130409T1 (en) 2013-06-30
NI201100102A (es) 2011-09-27
KR101374412B1 (ko) 2014-03-17
HK1161261A1 (en) 2012-08-24
SI2370442T1 (sl) 2013-06-28
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US20130197008A1 (en) 2013-08-01
DK2370442T5 (da) 2013-09-23
AU2009321221A1 (en) 2010-06-03
PT2370442E (pt) 2013-06-27
AP2011005732A0 (en) 2011-06-30
JP2012509931A (ja) 2012-04-26
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CN102227429A (zh) 2011-10-26
RS52810B8 (sr) 2019-08-30
NZ592919A (en) 2013-05-31
EP2370442A1 (en) 2011-10-05
US8946413B2 (en) 2015-02-03
US8293903B2 (en) 2012-10-23
ME01144B (me) 2013-03-20
DK2370442T3 (da) 2013-06-17
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EA020470B1 (ru) 2014-11-28
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PL2370442T3 (pl) 2013-08-30
US20110144129A1 (en) 2011-06-16
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TN2011000254A1 (fr) 2012-12-17
CO6361921A2 (es) 2012-01-20
PE20110831A1 (es) 2011-11-20
UA99978C2 (en) 2012-10-25
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AP3113A (en) 2015-01-31
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CA2743030A1 (en) 2010-06-03
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DOP2011000154A (es) 2011-07-31
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RS52810B9 (sr) 2019-06-28
MA32834B1 (fr) 2011-11-01
ZA201104069B (en) 2012-02-29
AU2009321221B2 (en) 2013-04-04
EA201170721A1 (ru) 2011-12-30
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HRP20130409T2 (hr) 2013-11-22

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