CO6361921A2 - 3-aminociclopentancarboxamidas - Google Patents

3-aminociclopentancarboxamidas

Info

Publication number
CO6361921A2
CO6361921A2 CO11064157A CO11064157A CO6361921A2 CO 6361921 A2 CO6361921 A2 CO 6361921A2 CO 11064157 A CO11064157 A CO 11064157A CO 11064157 A CO11064157 A CO 11064157A CO 6361921 A2 CO6361921 A2 CO 6361921A2
Authority
CO
Colombia
Prior art keywords
activity
aminociclopentancarboxamidas
ccr2
ccr5
modulates
Prior art date
Application number
CO11064157A
Other languages
English (en)
Inventor
Ronald Turner Steven
Rajesh Venkateswaran Devraj
Wei Huang
Robert Owen Hughes
Donald Joseph Rogier Jr
Jhon Isidro Trujillo
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of CO6361921A2 publication Critical patent/CO6361921A2/es

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    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/08—Bridged systems
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A61K31/407—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil condensed with other heterocyclic ring systems, e.g. ketorolac, physostigmine
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    • A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Abstract

Se provee un compuesto de la Fórmula I(a) o I(b):o una sal de éste farmacéuticamente aceptable los cuales modulan la actividad de receptores de quimiocina, tales como CCR2 y CCR5. Los compuestos se pueden usar, por ejemplo, para tratar enfermedades asociadas con la expresión o actividad del receptor de quimiocina, en donde varios sustituyentes se definen en la presente.
CO11064157A 2008-11-26 2011-05-24 3-aminociclopentancarboxamidas CO6361921A2 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US11805308P 2008-11-26 2008-11-26

Publications (1)

Publication Number Publication Date
CO6361921A2 true CO6361921A2 (es) 2012-01-20

Family

ID=41693100

Family Applications (1)

Application Number Title Priority Date Filing Date
CO11064157A CO6361921A2 (es) 2008-11-26 2011-05-24 3-aminociclopentancarboxamidas

Country Status (39)

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US (2) US8293903B2 (es)
EP (1) EP2370442B9 (es)
JP (1) JP5108153B2 (es)
KR (1) KR101374412B1 (es)
CN (1) CN102227429B (es)
AP (1) AP3113A (es)
AU (1) AU2009321221B2 (es)
BR (1) BRPI0920936A2 (es)
CA (1) CA2743030C (es)
CL (1) CL2011001223A1 (es)
CO (1) CO6361921A2 (es)
CR (1) CR20110275A (es)
CU (1) CU24022B1 (es)
CY (1) CY1114020T1 (es)
DK (1) DK2370442T5 (es)
DO (1) DOP2011000154A (es)
EA (1) EA020470B1 (es)
EC (1) ECSP11011081A (es)
ES (1) ES2415430T3 (es)
GE (1) GEP20146064B (es)
HK (1) HK1161261A1 (es)
HR (1) HRP20130409T2 (es)
IL (1) IL212732A (es)
MA (1) MA32834B1 (es)
ME (1) ME01144B (es)
MX (1) MX2011005526A (es)
MY (1) MY152557A (es)
NI (1) NI201100102A (es)
NZ (1) NZ592919A (es)
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WO2010061329A1 (en) * 2008-11-26 2010-06-03 Pfizer Inc. 3-aminocyclopentanecarboxamides as chemokine receptor modulators
KR101303963B1 (ko) * 2011-04-08 2013-09-05 재단법인 경기과학기술진흥원 (1ｒ,2ｒ,3ｒ)-3-아미노사이클로펜탄-1,2-디올을 포함하는 항알러지용 조성물
KR102456088B1 (ko) 2014-04-04 2022-10-19 델 마 파마슈티컬스 폐의 비소세포 암종 및 난소암을 치료하기 위한 디안하이드로갈락티톨 및 이의 유사체 또는 유도체
JP2016029038A (ja) * 2014-07-17 2016-03-03 参天製薬株式会社 加齢黄斑変性の予防または治療剤
JOP20190040A1 (ar) * 2016-09-14 2019-03-10 Novartis Ag توليفة من ناهضات fxr
WO2019215268A1 (en) * 2018-05-11 2019-11-14 Astrazeneca Ab Cyclopentane compounds
JP7412034B1 (ja) 2022-11-02 2024-01-12 鈴木製機株式会社 搬送システム

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CU24022B1 (es) 2014-07-30
EP2370442A1 (en) 2011-10-05
CN102227429A (zh) 2011-10-26
CA2743030C (en) 2013-10-22
EA020470B1 (ru) 2014-11-28
IL212732A (en) 2016-06-30
CL2011001223A1 (es) 2011-09-02
ECSP11011081A (es) 2011-12-30
AP3113A (en) 2015-01-31
ZA201104069B (en) 2012-02-29
TN2011000254A1 (fr) 2012-12-17
MY152557A (en) 2014-10-31
ME01144B (me) 2013-03-20
JP2012509931A (ja) 2012-04-26
US20110144129A1 (en) 2011-06-16
US8293903B2 (en) 2012-10-23
HRP20130409T2 (hr) 2013-11-22
CR20110275A (es) 2011-07-01
BRPI0920936A2 (pt) 2020-08-11
CN102227429B (zh) 2014-05-28
MA32834B1 (fr) 2011-11-01
RS52810B8 (sr) 2019-08-30
JP5108153B2 (ja) 2012-12-26
SI2370442T1 (sl) 2013-06-28
KR101374412B1 (ko) 2014-03-17
EP2370442B9 (en) 2013-09-04
PL2370442T3 (pl) 2013-08-30
RS52810B (en) 2013-10-31
US8946413B2 (en) 2015-02-03
EA201170721A1 (ru) 2011-12-30
GEP20146064B (en) 2014-03-25
EP2370442B1 (en) 2013-04-24
DK2370442T3 (da) 2013-06-17
ES2415430T9 (es) 2013-11-25
IL212732A0 (en) 2011-07-31
NI201100102A (es) 2011-09-27
CY1114020T1 (el) 2016-07-27
WO2010061329A1 (en) 2010-06-03
RS52810B9 (sr) 2019-06-28
AU2009321221B2 (en) 2013-04-04
AU2009321221A1 (en) 2010-06-03
PT2370442E (pt) 2013-06-27
KR20110075036A (ko) 2011-07-05
UA99978C2 (en) 2012-10-25
CA2743030A1 (en) 2010-06-03
DOP2011000154A (es) 2011-07-31
HRP20130409T1 (en) 2013-06-30
SV2011003923A (es) 2011-07-28
US20130197008A1 (en) 2013-08-01
DK2370442T5 (da) 2013-09-23
AP2011005732A0 (en) 2011-06-30
PE20110831A1 (es) 2011-11-20
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