EA025322B1 - Производные дигидробензооксазина и дигидропиридооксазина - Google Patents

Производные дигидробензооксазина и дигидропиридооксазина Download PDF

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Publication number
EA025322B1
EA025322B1 EA201491247A EA201491247A EA025322B1 EA 025322 B1 EA025322 B1 EA 025322B1 EA 201491247 A EA201491247 A EA 201491247A EA 201491247 A EA201491247 A EA 201491247A EA 025322 B1 EA025322 B1 EA 025322B1
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EA
Eurasian Patent Office
Prior art keywords
oxazin
yloxy
pyrrolidin
dihydro
benzo
Prior art date
Application number
EA201491247A
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English (en)
Russian (ru)
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EA201491247A1 (ru
Inventor
Джорджо Караватти
Сильви Шамуан
Паскаль Фюре
Клеменс Хегенауэр
Констанце Хурт
Кристоф Калис
Карен Каммертэн
Иан Левис
Хенрик Мебитц
Александер Бакстер Смит
Николя Солдерманн
Ромайн Вольф
Фредерик Зекри
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Новартис Аг
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Publication of EA201491247A1 publication Critical patent/EA201491247A1/ru
Publication of EA025322B1 publication Critical patent/EA025322B1/ru

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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/53831,4-Oxazines, e.g. morpholine ortho- or peri-condensed with heterocyclic ring systems
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    • A61K31/535Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
    • A61K31/53751,4-Oxazines, e.g. morpholine
    • A61K31/5381,4-Oxazines, e.g. morpholine ortho- or peri-condensed with carbocyclic ring systems
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EA201491247A 2011-12-22 2012-12-20 Производные дигидробензооксазина и дигидропиридооксазина EA025322B1 (ru)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201161579231P 2011-12-22 2011-12-22
PCT/IB2012/057554 WO2013093849A1 (en) 2011-12-22 2012-12-20 Dihydro-benzo-oxazine and dihydro-pyrido-oxazine derivatives

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Publication Number Publication Date
EA201491247A1 EA201491247A1 (ru) 2014-09-30
EA025322B1 true EA025322B1 (ru) 2016-12-30

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CN105541698B (zh) * 2015-12-23 2018-07-10 滨海康杰化学有限公司 一种5-溴-2-三氟甲基吡啶的制备方法
GB2550437B (en) * 2016-05-20 2021-06-23 Bugworks Res Inc Heterocyclic compounds useful as anti-bacterial agents and method for production
RU2020124136A (ru) * 2017-12-22 2022-01-25 Хиберселл, Инк. Производные хроменопиридина в качестве ингибиторов фосфатидилинозитолфосфаткиназы
LT3837263T (lt) 2018-08-13 2024-09-25 F. Hoffmann-La Roche Ag Nauji heterocikliniai junginiai kaip monoacilglicerolio lipazės inhibitoriai
JP7417540B2 (ja) 2018-12-06 2024-01-18 第一三共株式会社 シクロアルカン-1,3-ジアミン誘導体
TW202112784A (zh) 2019-06-17 2021-04-01 美商佩特拉製藥公司 作為磷脂酸肌醇磷酸激酶抑制劑之𠳭唏并嘧啶衍生物
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