DE279887C
(da)
|
|
|
|
|
FR960299A
(da)
|
|
1950-04-15 |
|
|
US3830797A
(en)
|
1964-11-05 |
1974-08-20 |
Pennwalt Corp |
Tertiary-aliphatic-alpha-(peracyl)azo compounds
|
US5874424A
(en)
|
1995-12-20 |
1999-02-23 |
Vertex Pharmaceuticals Incorporated |
Inhibitors of interleukin-1β converting enzyme
|
US3524858A
(en)
|
1967-05-18 |
1970-08-18 |
Warner Lambert Pharmaceutical |
1,4 - dihydro-1-substituted alkyl-6,7-methylenedioxy - 4 - oxoquinoline-3-carboxylic acid
|
US3751406A
(en)
|
1967-07-24 |
1973-08-07 |
Polaroid Corp |
Azo compounds useful in photographic processes
|
DE1908548A1
(de)
|
1968-02-29 |
1970-11-05 |
Warner Lambert Co |
Chinolinderivate
|
BE757639A
(fr)
|
1969-10-17 |
1971-04-16 |
Roussel Uclaf |
Nouveaux derives de la cephalosporine et procede de preparation
|
AT308173B
(de)
|
1970-02-03 |
1973-06-25 |
Maurer Friedrich Soehne |
Überbrückungsvorrichtung für Dehnungsfugen in Brücken od. dgl.
|
US4110355A
(en)
|
1972-12-26 |
1978-08-29 |
Polaroid Corporation |
Anthraquinone compounds useful in photographic processes
|
US3931145A
(en)
|
1972-12-27 |
1976-01-06 |
Gaf Corporation |
Keto-amido containing phenylazophenyl dyestuffs
|
GB1433774A
(en)
|
1973-02-26 |
1976-04-28 |
Allen & Hanburys Ltd |
Heterocyclic compounds apparatus for conveying articles
|
GB1433151A
(en)
|
1973-04-05 |
1976-04-22 |
Allen & Hanburys Ltd |
Benzo-ij-quinolizines
|
FR2281761A1
(fr)
|
1974-08-13 |
1976-03-12 |
Roussel Uclaf |
Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
|
FR2324304A2
(fr)
|
1975-09-22 |
1977-04-15 |
Roussel Uclaf |
Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
|
FR2340092A2
(fr)
|
1976-02-09 |
1977-09-02 |
Roussel Uclaf |
Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
|
FR2340735A1
(fr)
|
1976-02-11 |
1977-09-09 |
Roussel Uclaf |
Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
|
JPS5441319A
(en)
|
1977-06-28 |
1979-04-02 |
Uni Sutorasukuraido Za |
Pharmaceutical composition for treating tropic desease
|
DE2808070A1
(de)
|
1978-02-24 |
1979-08-30 |
Bayer Ag |
Verfahren zur herstellung von 4-pyridon-3-carbonsaeuren und/oder deren derivaten
|
FR2443467A1
(fr)
|
1978-12-08 |
1980-07-04 |
Roussel Uclaf |
Nouveaux derives de l'acide 3-quinoleine carboxylique, leur procede de preparation et leur application comme medicament
|
US4312870A
(en)
|
1979-06-21 |
1982-01-26 |
Ciba-Geigy Corporation |
Pyrazoloquinolines
|
JPS56110612A
(en)
|
1980-02-08 |
1981-09-01 |
Yamanouchi Pharmaceut Co Ltd |
Readily disintegrable and absorbable compression molded article of slightly soluble drug
|
US4390541A
(en)
|
1980-12-19 |
1983-06-28 |
Lilly Industries Limited |
Quinolone derivatives and their use in a method of controlling an immediate hypersensitivity disease
|
HU190796B
(en)
|
1981-06-12 |
1986-11-28 |
Roussel Uclaf,Fr |
Process for producing n-dihydrothiazolyl-3-quinoline-carboxamide derivatives
|
FR2509728A1
(fr)
|
1981-07-17 |
1983-01-21 |
Roussel Uclaf |
Nouveaux derives de la quinoleine, leurs sels, procede de preparation, application a titre de medicaments et compositions les renfermant
|
US4638067A
(en)
|
1982-09-09 |
1987-01-20 |
Warner-Lambert Co. |
Antibacterial agents
|
US5281612A
(en)
|
1982-09-09 |
1994-01-25 |
Warner-Lambert Company |
Naphthyridine antibacterial agents
|
FR2537140B1
(fr)
|
1982-12-07 |
1986-07-18 |
Roussel Uclaf |
Nouveaux derives de la 4-hydroxy-3-quinoleine carboxamide, leur sels, procede de preparation, application a titre de medicaments, et compositions les renfermant
|
SU1360584A3
(ru)
|
1983-08-12 |
1987-12-15 |
Варнер-Ламберт Компани (Фирма) |
Способ получени нафтиридинхинолин-или бензоксазинкарбоновых кислот или их фармацевтически допустимых солей присоединени кислоты
|
US4845105A
(en)
|
1984-10-30 |
1989-07-04 |
Roussel Uclaf |
4-OH-quinoline carboxylic acid amides having analgesic and anti-inflammatory activity
|
EP0180548B1
(de)
|
1984-11-01 |
1989-06-28 |
Ciba-Geigy Ag |
Gegen Lichteinwirkung stabilisierte Ueberzugsmittel
|
DE3702393A1
(de)
|
1987-01-28 |
1988-08-11 |
Bayer Ag |
8-cyano-1-cyclopropyl-1,4-dihydro-4-oxo- 3-chinolincarbonsaeuren, verfahren zu ihrer herstellung und diese enthaltende antibakterielle mittel
|
US4777252A
(en)
|
1987-08-13 |
1988-10-11 |
E. R. Squibb & Sons, Inc. |
2-oxo-1-[[(substituted sulfonyl)amino]-carbonyl]azetidines
|
DE3827253A1
(de)
|
1987-08-20 |
1989-03-02 |
Sandoz Ag |
Ester und amide von cyclischen carbonsaeuren und cyclischen alkoholen und aminen sowie verfahren zu deren herstellung und sie enthaltende therapeutische zusammensetzungen
|
HU206494B
(en)
|
1987-08-27 |
1992-11-30 |
Sumitomo Chemical Co |
Process for producing 3-fluoro-4-amino-phenol
|
DE3731516A1
(de)
|
1987-09-18 |
1989-03-30 |
Bayer Ag |
N-aryl-stickstoffheterocyclen
|
DE3811341A1
(de)
|
1987-10-09 |
1989-04-27 |
Bayer Ag |
In 7-stellung c-verknuepfte chinolon- und 1,8-naphthyridin-4-on-carbonsaeure und ein verfahren zu ihrer herstellung
|
US4786644A
(en)
|
1987-11-27 |
1988-11-22 |
Hoechst-Roussel Pharmaceuticals Inc. |
1-aryl-3-quinolinecarboxamide
|
DE3808118A1
(de)
|
1988-03-11 |
1989-09-21 |
Bayer Ag |
Verfahren zur herstellung von 1-cyclopropyl-chinoloncarbonsaeuren und deren derivaten
|
DE3808117A1
(de)
|
1988-03-11 |
1989-09-21 |
Bayer Ag |
N-cyclopropylaniline und deren verwendung in verfahren zur herstellung von 1-cyclopropyl-chinoloncarbonsaeuren und deren derivaten
|
DE3816119A1
(de)
|
1988-05-11 |
1989-11-23 |
Bayer Ag |
7-substituierte chinolon- und naphthyridoncarbonsaeure-derivate
|
JPH01287066A
(ja)
|
1988-05-13 |
1989-11-17 |
Fujimoto Seiyaku Kk |
新規なアントラニル酸誘導体
|
DK273689A
(da)
|
1988-06-06 |
1989-12-07 |
Sanofi Sa |
4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
|
DE3827221A1
(de)
|
1988-08-11 |
1990-02-15 |
Bayer Ag |
Substituierte n-phenyl-stickstoff- bzw. stickstoff-schwefel-heterocyclen, verfahren sowie entsprechende heterocyclische phenolderivate, phenyliso(thio)cyanate und -carbamate als zwischenprodukte zu ihrer herstellung, ihre verwendung in herbiziden und pflanzenwuchsregulierenden mitteln
|
US5491139A
(en)
|
1988-10-24 |
1996-02-13 |
The Procter & Gamble Company |
Antimicrobial quinolonyl lactams
|
DE3903799A1
(de)
|
1989-02-09 |
1990-08-16 |
Bayer Ag |
N-aryl-stickstoffheterocyclen
|
JPH0334977A
(ja)
|
1989-06-29 |
1991-02-14 |
Yoshitomi Pharmaceut Ind Ltd |
イミダゾリルベンゾラクタム化合物
|
DE3924052A1
(de)
|
1989-07-21 |
1991-01-24 |
Bayer Ag |
N- (indol-6-yl)-heterocyclen
|
EP0418596A3
(en)
*
|
1989-09-21 |
1991-10-23 |
American Cyanamid Company |
Controlled release pharmaceutical compositions from spherical granules in tabletted oral dosage unit form
|
GB2236751B
(en)
|
1989-10-14 |
1993-04-28 |
Wyeth John & Brother Ltd |
Heterocyclic compounds
|
US5254135A
(en)
|
1989-10-20 |
1993-10-19 |
L'oreal |
Methods for dyeing keratinous fibres with aminoindoles, compositions and devices for use
|
FR2659552B2
(fr)
|
1989-10-20 |
1994-11-04 |
Oreal |
Procede de teinture des fibres keratiniques avec des aminoindoles, composition et dispositif de mise en óoeuvre.
|
LU87611A1
(fr)
|
1989-10-20 |
1991-05-07 |
Oreal |
Composition tinctoriale pour fibres keratiniques contenant des precurseurs de colorants par oxydation et des coupleurs amino indoliques,procedes de teinture mettant en oeuvre ces compositions et composes nouveaux
|
FR2662713B1
(fr)
|
1990-05-29 |
1994-04-08 |
Oreal |
Procede de teinture de fibres keratiniques avec un aminoindole associe a un derive quinonique.
|
DE4017516A1
(de)
|
1990-05-31 |
1991-12-05 |
Wella Ag |
Oxidationshaarfaerbemittel mit einem gehalt an 3-aminophenol-derivaten, verfahren zum oxidativen faerben von haaren sowie neue 3-aminophenol-derivate
|
US5409503A
(en)
|
1990-05-31 |
1995-04-25 |
Wella Aktiengesellschaft |
Oxidation hair dye with a content of 5-aminophenyl derivatives, process for oxidative dyeing of hair and new 5-aminophenol derivatives
|
DE4026530A1
(de)
|
1990-08-22 |
1992-02-27 |
Basf Ag |
Synergistische mittel zur regulierung des pflanzenwachstums
|
CA2091172C
(en)
|
1990-09-07 |
1997-05-20 |
Adriano Afonso |
Antiviral compounds and antihypertensive compounds
|
US5175151A
(en)
|
1990-09-07 |
1992-12-29 |
Schering Corporation |
Antiviral compounds and antihypertensive compounds
|
AU8448491A
(en)
|
1990-09-07 |
1992-03-30 |
Schering Corporation |
Antiviral compounds and antihypertensive compounds
|
IL100917A0
(en)
|
1991-02-16 |
1992-11-15 |
Fisons Plc |
Pyridinone and pyrimidinone derivatives,their preparation and pharmaceutical compositions containing them
|
RU1796623C
(ru)
|
1991-03-11 |
1993-02-23 |
Институт химии Башкирского научного центра Уральского отделения АН СССР |
Способ получени этилового эфира 6,7-дифтор-1,4-дигидро-4-оксо-3-хинолинкарбоновой кислоты
|
CA2065106A1
(en)
|
1991-04-04 |
1992-10-05 |
Junichi Fukawa |
Silver halide photographic light-sensitive material and photographic product for film-making process
|
US5938792A
(en)
|
1991-04-18 |
1999-08-17 |
L'oreal |
Process for dyeing keratinous fibers with aminoindoles and oxidation dye precursors at basic Ph's and dyeing agents
|
FR2675380A1
(fr)
|
1991-04-18 |
1992-10-23 |
Oreal |
Procede de teinture des fibres keratiniques avec des aminoindoles, a ph basique, compositions mises en óoeuvre et nouveaux composes.
|
GB9108547D0
(en)
|
1991-04-22 |
1991-06-05 |
Fujisawa Pharmaceutical Co |
Quinoline derivatives
|
SK117793A3
(en)
|
1991-04-29 |
1994-05-11 |
Merck & Co Inc |
Optimized tablet formulation
|
CA2075154A1
(en)
|
1991-08-06 |
1993-02-07 |
Neelakantan Balasubramanian |
Peptide aldehydes as antithrombotic agents
|
JPH05345780A
(ja)
|
1991-12-24 |
1993-12-27 |
Kumiai Chem Ind Co Ltd |
ピリミジンまたはトリアジン誘導体及び除草剤
|
EP0641204B1
(en)
|
1992-05-20 |
2000-08-16 |
Merck & Co. Inc. |
17-ethers and thioethers of 4-aza-steroids
|
DE69329856D1
(de)
|
1992-05-20 |
2001-02-15 |
Merck & Co Inc |
Ester derivate von 4-aza-steroiden
|
JPH0672979A
(ja)
|
1992-06-08 |
1994-03-15 |
Hiroyoshi Hidaka |
アミノベンジル誘導体
|
RU2047614C1
(ru)
|
1992-06-15 |
1995-11-10 |
Джон Вайс энд Бразер Лимитед |
Гетероциклические соединения, или их фармацевтически приемлемые аддитивные соли кислоты, или n-оксид гетероциклического соединения, или его аддитивная соль кислоты
|
US5352690A
(en)
|
1992-07-01 |
1994-10-04 |
Eli Lilly And Company |
1,2,4-trioxygenated benzene derivatives useful as leukotriene antagonists
|
AU4567193A
(en)
|
1992-07-10 |
1994-01-31 |
Laboratoires Glaxo S.A. |
Anilide derivatives
|
US5322847A
(en)
|
1992-11-05 |
1994-06-21 |
Pfizer Inc. |
Azabenzimidazoles in the treatment of asthma, arthritis and related diseases
|
WO1994014797A1
(en)
|
1992-12-23 |
1994-07-07 |
Smithkline Beecham Corporation |
Quinoline compounds and the treatment of leucotriene related diseases therewith
|
US5750754A
(en)
|
1993-03-29 |
1998-05-12 |
Zeneca Limited |
Heterocyclic compounds
|
JP3760474B2
(ja)
|
1993-04-22 |
2006-03-29 |
ダイキン工業株式会社 |
電気エネルギーを発生させる方法、装置およびそれに用いるn−f結合を有する化合物
|
JPH0733729A
(ja)
|
1993-07-26 |
1995-02-03 |
Kirin Brewery Co Ltd |
N−シアノ−n′−置換−アリールカルボキシイミダミド化合物の製造法
|
JPH0782498A
(ja)
|
1993-09-17 |
1995-03-28 |
Fuji Photo Film Co Ltd |
ビスアゾ化合物
|
IL111266A
(en)
|
1993-10-22 |
2002-03-10 |
Zeneca Ltd |
2-HETEROARYL OR 2-ARYLPYRIDAZINO [4,5-b] QUINOLINE - 1, 10 - DIONES, THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM
|
JPH07179407A
(ja)
|
1993-11-12 |
1995-07-18 |
Green Cross Corp:The |
新規縮合環系化合物またはその塩、およびその医薬用途
|
EP0746561B1
(en)
|
1994-02-25 |
1999-04-28 |
Laboratorios Aranda, S.A. De C.V. (Mx/Mx) |
Quinolonylcarboxamidocephalosporin derivatives and pharmaceutical compositions containing them
|
FR2720397B1
(fr)
|
1994-05-24 |
1996-08-23 |
Laphal Laboratoires Sa |
Nouveaux oxathiolanes, leur procédé de préparation et les compositions pharmaceutiques qui en renferment.
|
ITMI941099A1
(it)
|
1994-05-27 |
1995-11-27 |
Smithkline Beecham Farma |
Derivati chinolinici
|
ATE246677T1
(de)
|
1994-05-27 |
2003-08-15 |
Smithkline Beecham Farma |
Chinolinderivate als tachykinin nk3 rezeptor antagonisten
|
EP0705835A1
(de)
|
1994-09-01 |
1996-04-10 |
Ciba-Geigy Ag |
Oxa- oder thiaaliphatisch überbrückte Chinoxalin-2,3-dione
|
WO1996015099A1
(en)
|
1994-11-09 |
1996-05-23 |
Novo Nordisk A/S |
Heterocyclic compounds, their preparation and use
|
AU4314196A
(en)
|
1994-12-21 |
1996-07-10 |
Yamanouchi Pharmaceutical Co., Ltd. |
Solid composition with improved solubility and absorbability
|
GB9501567D0
(en)
|
1995-01-26 |
1995-03-15 |
Pharmacia Spa |
Hydrosoluble 3-arylidene-2-oxindole derivatives as tyrosine kinase inhibitors
|
JPH08301849A
(ja)
|
1995-05-01 |
1996-11-19 |
Takeda Chem Ind Ltd |
ヘテロ環化合物およびその製造法
|
JPH0971534A
(ja)
|
1995-06-26 |
1997-03-18 |
Tanabe Seiyaku Co Ltd |
医薬組成物
|
DE19601142A1
(de)
|
1995-07-13 |
1997-01-16 |
Agfa Gevaert Ag |
Verfahren zur Erzeugung eines farbigen Bildes
|
ATE258437T1
(de)
|
1995-08-02 |
2004-02-15 |
Darwin Discovery Ltd |
Chinolone und deren therapeutische verwendung
|
EP0841929B1
(en)
|
1995-08-02 |
2003-05-07 |
Darwin Discovery Limited |
Quinolones and their therapeutic use
|
DE19532235A1
(de)
|
1995-08-31 |
1997-03-06 |
Keppler Bernhard K Priv Doz Dr |
An Phosphonsäuren gekoppelte antibakteriell wirksame Verbindungen zur Therapie von Infektionen im Bereich des Knochens
|
DE69623655T2
(de)
|
1995-10-19 |
2003-04-24 |
Takeda Chemical Industries, Ltd. |
Chinolinderivate als gnrh antagonisten
|
NZ325248A
(en)
|
1995-12-23 |
1999-09-29 |
Pfizer Res & Dev |
Quinoline and quinazoline compounds useful in therapy
|
WO1997030999A1
(en)
|
1996-02-21 |
1997-08-28 |
Darwin Discovery Limited |
Quinolones and their therapeutic use
|
US6215016B1
(en)
|
1996-03-27 |
2001-04-10 |
Toray Industries, Inc. |
Ketone derivatives and medical application thereof
|
DE19615262A1
(de)
|
1996-04-18 |
1997-10-23 |
Bayer Ag |
Heteroverknüpfte Phenylglycinolamide
|
BR9709105A
(pt)
|
1996-05-20 |
1999-08-03 |
Darwin Discovery Ltd |
Sulfonamidas de quinolina como inibidoras de tnf e como inobidoras de pde-iv
|
PL329922A1
(en)
|
1996-05-20 |
1999-04-26 |
Darwin Discovery Ltd |
Quinoline carboxamides as inhibitors of the tumour necrosis factor and of phosphodiesterase
|
CA2258822A1
(en)
|
1996-06-20 |
1997-12-24 |
Sean Kerwin |
Compounds and methods for providing pharmacologically active preparations and uses thereof
|
AU3671897A
(en)
|
1996-07-23 |
1998-02-10 |
Neurogen Corporation |
Certain amido- and amino-substituted benzylamine derivatives; a new class of neuropeptite y1 specific ligands
|
GB9717576D0
(en)
|
1997-08-19 |
1997-10-22 |
Xenova Ltd |
Pharmaceutical compounds
|
US6069151A
(en)
|
1996-11-06 |
2000-05-30 |
Darwin Discovery, Ltd. |
Quinolines and their therapeutic use
|
DE19651099A1
(de)
|
1996-12-09 |
1998-06-10 |
Consortium Elektrochem Ind |
Mehrkomponentensystem zum Verändern, Abbau oder Bleichen von Lignin, ligninhaltigen Materialien oder ähnlichen Stoffen sowie Verfahren zu seiner Anwendung
|
AU6209098A
(en)
|
1997-01-15 |
1998-08-07 |
Novartis Ag |
Herbicidal agent
|
US5948814A
(en)
|
1997-02-20 |
1999-09-07 |
The Curators Of The University Of Missouri |
Genistein for the treatment of cystic fibrosis
|
ZA986594B
(en)
|
1997-07-25 |
1999-01-27 |
Abbott Lab |
Urokinase inhibitors
|
US6258822B1
(en)
|
1997-08-06 |
2001-07-10 |
Abbott Laboratories |
Urokinase inhibitors
|
EP0901786B1
(en)
|
1997-08-11 |
2007-06-13 |
Pfizer Products Inc. |
Solid pharmaceutical dispersions with enhanced bioavailability
|
IL133420A
(en)
*
|
1997-08-26 |
2004-07-25 |
Aventis Pharma Inc |
Tablet-shaped pharmaceutical preparation containing a combination of piperidinoalkanol and antihistamines and reduces symptomatic congestion
|
US6429207B1
(en)
|
1997-11-21 |
2002-08-06 |
Nps Pharmaceuticals, Inc. |
Metabotropic glutamate receptor antagonists and their use for treating central nervous system diseases
|
TR200002616T2
(tr)
|
1997-12-22 |
2000-11-21 |
Bayer Corporation |
Simetrik ve simetrik olmayan sübstitüe edilmiş difenil üreler kullanılarak raf kinazın inhibe edilmesi
|
WO1999046267A1
(en)
|
1998-03-12 |
1999-09-16 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases (ptpases)
|
WO1999046237A1
(en)
|
1998-03-12 |
1999-09-16 |
Novo Nordisk A/S |
Modulators of protein tyrosine phosphatases
|
DE19818614A1
(de)
|
1998-04-20 |
1999-10-21 |
Basf Ag |
Neue substituierte Amide, deren Herstellung und Anwendung
|
JP2000016982A
(ja)
|
1998-06-30 |
2000-01-18 |
Kumiai Chem Ind Co Ltd |
キノリン誘導体及びこれを有効成分とする除草剤
|
US6133285A
(en)
|
1998-07-15 |
2000-10-17 |
Active Biotech Ab |
Quinoline derivatives
|
WO2000006549A1
(fr)
|
1998-07-28 |
2000-02-10 |
Nihon Nohyaku Co., Ltd. |
Derives de diamide dicarboxylique a heterocycle condense ou sels de ceux-ci, herbicides et leur utilisation
|
TR200100286T2
(tr)
|
1998-08-03 |
2001-07-23 |
Applied Research Systems Ars Holding N.V. |
(1H)-Benzo[C]kuinolizin-3-on türevlerinin sentezi için proses.
|
US7001770B1
(en)
|
1998-10-15 |
2006-02-21 |
Canji, Inc. |
Calpain inhibitors and their applications
|
FR2786483B1
(fr)
|
1998-12-01 |
2001-02-16 |
Rhodia Chimie Sa |
Procede de preparation de 4-hydroxyquinoleines et/ou formes tautomeres
|
US6248736B1
(en)
|
1999-01-08 |
2001-06-19 |
Pharmacia & Upjohn Company |
4-oxo-1,4-dihydro-3-quinolinecarboxamides as antiviral agents
|
US6248739B1
(en)
|
1999-01-08 |
2001-06-19 |
Pharmacia & Upjohn Company |
Quinolinecarboxamides as antiviral agents
|
DK1033364T3
(da)
|
1999-03-01 |
2005-06-06 |
Pfizer Prod Inc |
Cyanholdige oxamidsyrer og -derivater som thyroideareceptorligander
|
JP2000256358A
(ja)
|
1999-03-10 |
2000-09-19 |
Yamanouchi Pharmaceut Co Ltd |
ピラゾール誘導体
|
CA2371472A1
(en)
|
1999-05-06 |
2000-11-16 |
Neurogen Corporation |
Substituted 4-oxo-quinoline-3-carboxamides: gaba brain receptor ligands
|
AR028299A1
(es)
|
1999-09-17 |
2003-05-07 |
Novartis Ag |
Una composicion farmaceutica que comprende nateglinida, un proceso para su preparacion y el uso de dicha composicion para la preparacion de un medicamento para el tratamiento de desordenes metabolicos, especialmente diabetes, o de una enfermedad o condicion asociada con diabetes.
|
SE0002320D0
(sv)
|
1999-10-25 |
2000-06-21 |
Active Biotech Ab |
Malignant tumors
|
RS51019B
(sr)
|
1999-10-25 |
2010-10-31 |
Active Biotech Ab. |
Lekovi za lečenje malignih tumora
|
WO2001030757A1
(fr)
|
1999-10-28 |
2001-05-03 |
Microcide Pharmaceuticals, Inc. |
Inhibiteurs de la pompe par liberation de medicaments
|
WO2001034570A1
(fr)
|
1999-11-08 |
2001-05-17 |
Sankyo Company, Limited |
Derives heterocycliques azotes
|
JP2001199965A
(ja)
|
1999-11-08 |
2001-07-24 |
Sankyo Co Ltd |
含窒素複素環誘導体
|
UA75055C2
(uk)
|
1999-11-30 |
2006-03-15 |
Пфайзер Продактс Інк. |
Похідні бензоімідазолу, що використовуються як антипроліферативний засіб, фармацевтична композиція на їх основі
|
GT200000203A
(es)
|
1999-12-01 |
2002-05-24 |
|
Compuestos, composiciones y metodos para estimular el crecimiento y elongacion de neuronas.
|
US20030181449A1
(en)
|
1999-12-23 |
2003-09-25 |
Urbanek Rebecca Ann |
Methods and compositions for the treatment of pain
|
JP2001233859A
(ja)
|
2000-02-23 |
2001-08-28 |
Yamanouchi Pharmaceut Co Ltd |
抗ヘリコバクター・ヒ゜ロリ化合物の新規製造法及びその中間体
|
GB0011409D0
(en)
|
2000-05-11 |
2000-06-28 |
Smithkline Beecham Plc |
Novel compounds
|
CA2405972C
(en)
|
2000-05-17 |
2010-03-23 |
Gottfried Seifert |
Process for the preparation of aniline compounds
|
US6800297B2
(en)
|
2000-06-15 |
2004-10-05 |
Acusphere, Inc. |
Porous COX-2 inhibitor matrices and methods of manufacture thereof
|
AU2001268691A1
(en)
|
2000-06-29 |
2002-01-21 |
Clairol Incorporated |
Iodo-containing organic couplers for use in oxidative hair dyeing
|
CN1441794A
(zh)
|
2000-07-13 |
2003-09-10 |
武田药品工业株式会社 |
富脂质斑退化剂
|
WO2002012189A1
(fr)
|
2000-08-09 |
2002-02-14 |
Mitsubishi Pharma Corporation |
Composes amide bicycliques condenses et utilisations medicales associees
|
WO2002038126A2
(en)
|
2000-11-08 |
2002-05-16 |
Aeromatic-Fielder Ag |
A process for production of particles for pharmaceutical compositions having increased bioavailability
|
JP2002212179A
(ja)
|
2001-01-15 |
2002-07-31 |
Wakunaga Pharmaceut Co Ltd |
新規アニリド誘導体又はその塩及びこれを含有する医薬
|
GB2372986A
(en)
|
2001-01-17 |
2002-09-11 |
Xenova Ltd |
2-oxo, 4-hydroxy pyrroles and quinolines
|
GB0102687D0
(en)
|
2001-02-02 |
2001-03-21 |
Pharmacia & Upjohn Spa |
Oxazolyl-pyrazole derivatives active as kinase inhibitors,process for their preparation and pharmaceutical compositions comprising them
|
US20100074949A1
(en)
|
2008-08-13 |
2010-03-25 |
William Rowe |
Pharmaceutical composition and administration thereof
|
TWI243164B
(en)
|
2001-02-13 |
2005-11-11 |
Aventis Pharma Gmbh |
Acylated indanyl amines and their use as pharmaceuticals
|
DE10108271A1
(de)
|
2001-02-21 |
2002-08-22 |
Schering Ag |
Chinolin-, Isochinolin- und Phthalazinderivate als Antagonisten des Gonadotropin freisetzenden Hormons
|
US6515001B2
(en)
|
2001-03-05 |
2003-02-04 |
Chemokine Therapeutic Corporation |
IL-8 receptor ligands-drugs for inflammatory and autoimmune diseases
|
DE10110750A1
(de)
|
2001-03-07 |
2002-09-12 |
Bayer Ag |
Neuartige Aminodicarbonsäurederivate mit pharmazeutischen Eigenschaften
|
DK1379239T3
(da)
|
2001-03-29 |
2008-01-07 |
Lilly Co Eli |
N(2-aryl-ethyl)-benzyl-aminer som antagonister af 5 HT6 receptoren
|
US6878713B2
(en)
|
2001-04-25 |
2005-04-12 |
Wockhardt Limited |
Generation triple-targeting, chiral, broad-spectrum antimicrobial 7-substituted piperidino-quinolone carboxylic acid derivatives, their preparation, compositions and use as medicaments
|
JP2002322054A
(ja)
|
2001-04-26 |
2002-11-08 |
Dai Ichi Seiyaku Co Ltd |
薬剤排出ポンプ阻害薬
|
JP2002322154A
(ja)
|
2001-04-27 |
2002-11-08 |
Dai Ichi Seiyaku Co Ltd |
抗真菌化合物
|
JP2002326935A
(ja)
|
2001-05-07 |
2002-11-15 |
Sankyo Co Ltd |
含窒素複素環誘導体を含有する医薬
|
CA2448076A1
(en)
|
2001-05-24 |
2002-11-28 |
Masahiko Hayakawa |
3-quinoline-2-(1h)-ylideneindolin-2-one derivatives
|
JP2003012667A
(ja)
|
2001-06-26 |
2003-01-15 |
Rrf Kenkyusho:Kk |
キノリンカルボキサミド骨格を有する抗菌剤
|
WO2003024409A2
(en)
|
2001-09-21 |
2003-03-27 |
Case Western Reserve University |
Q4n2neg2 enhances cftr activity
|
CA2462442A1
(en)
|
2001-10-12 |
2003-04-24 |
Warner-Lambert Company Llc |
Alkyne matrix metalloproteinase inhibitors
|
WO2003048135A1
(en)
|
2001-11-14 |
2003-06-12 |
Teva Pharmaceutical Industries Ltd. |
Amorphous and crystalline forms of losartan potassium and process for their preparation
|
TW200300349A
(en)
|
2001-11-19 |
2003-06-01 |
Sankyo Co |
A 4-oxoqinoline derivative
|
US7084156B2
(en)
|
2001-11-27 |
2006-08-01 |
Merck & Co., Inc. |
2-Aminoquinoline compounds
|
MXPA04005427A
(es)
|
2001-12-10 |
2005-04-19 |
Amgen Inc |
Ligandos de receptor vainilloide y su uso en tratamientos.
|
EP1469830A2
(en)
|
2002-02-01 |
2004-10-27 |
Pfizer Products Inc. |
Method for making homogeneous spray-dried solid amorphous drug dispersions using pressure nozzles
|
JP2003238413A
(ja)
|
2002-02-14 |
2003-08-27 |
Kyowa Hakko Kogyo Co Ltd |
ステロイドスルファターゼ阻害剤
|
DE20221945U1
(de)
|
2002-03-15 |
2009-10-15 |
Wella Aktiengesellschaft |
Chinolinium-Salze enthaltende Färbemittel
|
US6930131B2
(en)
|
2002-04-10 |
2005-08-16 |
Wyeth |
Aryl substituted 3-ethoxy phenyl trifluoromethane sulfonamides for the treatment of non-insulin dependent diabetes mellitus (NIDDM)
|
EP1500652A4
(en)
|
2002-04-26 |
2006-05-03 |
Nippon Shinyaku Co Ltd |
DERIVATIVE AND MEDICINAL PRODUCT OF QUINAZOLINE
|
US7037913B2
(en)
|
2002-05-01 |
2006-05-02 |
Bristol-Myers Squibb Company |
Bicyclo 4.4.0 antiviral derivatives
|
WO2003095447A1
(en)
|
2002-05-14 |
2003-11-20 |
Xenova Limited |
Process for the preparation of a hydrate of an anthranilic acid derivative
|
ES2319176T3
(es)
|
2002-05-14 |
2009-05-05 |
The Regents Of The University Of California |
Acidos quinolona-carboxilicos sustituidos, sus derivados, sitio de accion y uso de los mismos.
|
SE0201669D0
(sv)
|
2002-06-03 |
2002-06-03 |
Pharmacia Ab |
New formulation and use thereof
|
KR20050029209A
(ko)
|
2002-07-15 |
2005-03-24 |
미리어드 제네틱스, 인크. |
화합물, 조성물 및 이의 사용방법
|
US20040033959A1
(en)
|
2002-07-19 |
2004-02-19 |
Boehringer Ingelheim Pharmaceuticals, Inc. |
Pharmaceutical compositions for hepatitis C viral protease inhibitors
|
JP2006503008A
(ja)
|
2002-08-13 |
2006-01-26 |
ワーナー−ランバート カンパニー リミティド ライアビリティー カンパニー |
マトリクスメタロプロテイナーゼ阻害物質としての4−ヒドロキシキノリン誘導体
|
TWI314041B
(en)
|
2002-10-21 |
2009-09-01 |
Sankyo Agro Co Ltd |
Quinolyl-3-carboxamide compound
|
AR042206A1
(es)
|
2002-11-26 |
2005-06-15 |
Novartis Ag |
Acidos fenilaceticos y derivados
|
JP2004189738A
(ja)
|
2002-11-29 |
2004-07-08 |
Nippon Nohyaku Co Ltd |
置換アニリド誘導体、その中間体及び農園芸用薬剤並びにその使用方法
|
WO2004080972A1
(en)
|
2003-03-12 |
2004-09-23 |
Vertex Pharmaceuticals Incorporated |
Pirazole modulators of atp-binding cassette transporters
|
WO2004105779A2
(en)
|
2003-05-27 |
2004-12-09 |
Cesare Montecucco |
Green tea and oplyphenol inhibitors of bacterial proteases
|
DE602004022819D1
(de)
|
2003-06-06 |
2009-10-08 |
Vertex Pharma |
Von atp-bindende kassette transportern
|
CA2530352A1
(en)
|
2003-07-24 |
2005-02-03 |
Astellas Pharma Inc. |
Quinolone derivative or salt thereof
|
CN1191252C
(zh)
|
2003-08-11 |
2005-03-02 |
中国药科大学 |
3-位取代的喹诺酮衍生物及其在药学上的应用
|
RU2006111093A
(ru)
|
2003-09-06 |
2007-10-27 |
Вертекс Фармасьютикалз Инкорпорейтед (Us) |
Модуляторы атр-связывающих кассетных транспортеров
|
US20050059035A1
(en)
|
2003-09-09 |
2005-03-17 |
Quest Diagnostics Incorporated |
Methods and compositions for the amplification of mutations in the diagnosis of cystic fibrosis
|
DK1663182T4
(da)
*
|
2003-09-12 |
2020-02-17 |
Amgen Inc |
Hurtigt opløsende formulering af cinacalcet HCI
|
US7223759B2
(en)
|
2003-09-15 |
2007-05-29 |
Anadys Pharmaceuticals, Inc. |
Antibacterial 3,5-diaminopiperidine-substituted aromatic and heteroaromatic compounds
|
ZA200603515B
(en)
|
2003-10-08 |
2007-11-28 |
Vertex Pharma |
Modulators of ATP-binding cassette transporters
|
NZ547220A
(en)
|
2003-11-14 |
2009-12-24 |
Vertex Pharma |
Thiazoles and oxazoles useful as modulators of ATP-binding cassette transporters
|
CN100563658C
(zh)
|
2003-11-14 |
2009-12-02 |
味之素株式会社 |
苯丙氨酸衍生物的固体分散体或固体分散体医药制剂
|
US20050208095A1
(en)
|
2003-11-20 |
2005-09-22 |
Angiotech International Ag |
Polymer compositions and methods for their use
|
JP2007516259A
(ja)
|
2003-12-09 |
2007-06-21 |
メッドクリスタルフォームズ、エルエルシー |
活性剤との混合相共結晶の調製方法
|
US7977322B2
(en)
|
2004-08-20 |
2011-07-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
BRPI0507278A
(pt)
|
2004-01-30 |
2007-06-26 |
Vertex Pharma |
moduladores dos transportadores do cassete de ligação ao atp
|
JP2007519756A
(ja)
|
2004-01-30 |
2007-07-19 |
アンジオテック インターナショナル アーゲー |
拘縮を治療するための組成物および方法
|
SE0400235D0
(sv)
|
2004-02-06 |
2004-02-06 |
Active Biotech Ab |
New composition containing quinoline compounds
|
WO2005094805A1
(ja)
|
2004-04-01 |
2005-10-13 |
Institute Of Medicinal Molecular Design. Inc. |
イミン誘導体及びアミド誘導体
|
JP2006206612A
(ja)
|
2004-05-27 |
2006-08-10 |
Ono Pharmaceut Co Ltd |
固形製剤用組成物
|
EP1765347A4
(en)
|
2004-06-04 |
2008-10-01 |
Univ California |
COMPOUNDS WITH ION TRANSPORTER HEALING EFFECT BY MUTANT CFTR AND ITS USE
|
BRPI0511900A
(pt)
|
2004-06-08 |
2008-01-22 |
Vertex Pharma |
composições farmacêuticas
|
US8354427B2
(en)
|
2004-06-24 |
2013-01-15 |
Vertex Pharmaceutical Incorporated |
Modulators of ATP-binding cassette transporters
|
BR122018075478B8
(pt)
|
2004-06-24 |
2023-10-31 |
Vertex Pharma |
moduladores de transportadores de cassete de ligação de atp
|
US20140343098A1
(en)
|
2004-06-24 |
2014-11-20 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
WO2006014427A1
(en)
|
2004-07-02 |
2006-02-09 |
Advancis Pharmaceutical Corporation |
Tablet for pulsed delivery
|
AU2005286719B2
(en)
|
2004-09-21 |
2011-03-24 |
Bone Solutions, Inc. |
Multi-purpose bio-material composition
|
WO2006099256A2
(en)
|
2005-03-11 |
2006-09-21 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
RU2007138584A
(ru)
|
2005-03-18 |
2009-04-27 |
Дзе Риджентс Оф Дзе Юниверсити Оф Калифорния (Us) |
Соединения, обладающие активностью для коррекции процессинга мутантного cftr, и их применение
|
WO2006118017A1
(ja)
|
2005-04-28 |
2006-11-09 |
Eisai R & D Management Co., Ltd. |
安定化組成物
|
ATE533749T1
(de)
|
2005-05-24 |
2011-12-15 |
Vertex Pharma |
Modulatoren von atp-bindenden kassettentransportern
|
JP5143738B2
(ja)
|
2005-08-11 |
2013-02-13 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
嚢胞性線維症膜コンダクタンス制御因子の調節物質
|
ES2367844T3
(es)
|
2005-08-11 |
2011-11-10 |
Vertex Pharmaceuticals, Inc. |
Moduladores del regulador de la conductancia transmembrana de la fibrosis quística.
|
AU2006302371A1
(en)
|
2005-10-06 |
2007-04-19 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding cassette transporters
|
ES2439736T3
(es)
|
2005-11-08 |
2014-01-24 |
Vertex Pharmaceuticals Incorporated |
Moduladores heterocíclicos de transportadores de casete de unión a ATP
|
US20120232059A1
(en)
|
2005-11-08 |
2012-09-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette Transporters
|
US20080057047A1
(en)
|
2005-11-29 |
2008-03-06 |
Benedikt Sas |
Use of bacillus amyloliquefaciens PB6 for the prophylaxis or treatment of gastrointestinal and immuno-related diseases
|
WO2007067559A2
(en)
|
2005-12-06 |
2007-06-14 |
Regents Of The University Of Minnesota |
Antibacterial agents
|
US20090105272A1
(en)
|
2005-12-24 |
2009-04-23 |
Grootenhuis Peter D J |
Prodrugs of modulators of ABC transporters
|
BRPI0620578A2
(pt)
|
2005-12-27 |
2011-12-06 |
Jubilant Organosys Ltd |
composição farmacêutica que dissolve na boca e processo para o preparo da mesma
|
CA2635214A1
(en)
|
2005-12-27 |
2007-07-05 |
Vertex Pharmaceuticals Incorporated |
Compounds useful in cftr assays and methods therewith
|
US7671221B2
(en)
|
2005-12-28 |
2010-03-02 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
HUE049976T2
(hu)
|
2005-12-28 |
2020-11-30 |
Vertex Pharma |
N-[2,4-bisz(1,1-dimetil-etil)-5-hidroxi-fenil]-1,4-dihidro-4-oxo-kinolin-3-karboxamid amorf alakjának gyógyászati kompozíciói
|
CA2856037C
(en)
|
2005-12-28 |
2017-03-07 |
Vertex Pharmaceuticals Incorporated |
Modulators of atp-binding cassette transporters
|
CN101443314B
(zh)
|
2006-03-13 |
2014-04-09 |
杏林制药株式会社 |
作为gsk-3抑制剂的氨基喹诺酮类
|
WO2007106957A1
(en)
|
2006-03-21 |
2007-09-27 |
Laboratoires Smb S.A. |
Multiple units controlled-release floating dosage forms
|
US10022352B2
(en)
|
2006-04-07 |
2018-07-17 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-binding cassette transporters
|
RU2451018C2
(ru)
|
2006-04-07 |
2012-05-20 |
Вертекс Фармасьютикалз Инкорпорейтед |
Модуляторы атф-связывающих кассетных транспортеров
|
US7645789B2
(en)
|
2006-04-07 |
2010-01-12 |
Vertex Pharmaceuticals Incorporated |
Indole derivatives as CFTR modulators
|
NZ572201A
(en)
|
2006-04-20 |
2011-09-30 |
Janssen Pharmaceutica Nv |
Inhibitors of c-fms kinase
|
AU2007249269A1
(en)
|
2006-05-12 |
2007-11-22 |
Vertex Pharmaceuticals Incorporated |
Compositions of N-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl)-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
US20090285887A1
(en)
|
2006-09-12 |
2009-11-19 |
Omar Abdelfattah Abu-Baker |
Pharmaceutical Composition Comprising A Plurality of Mini-Tablets Comprising A Factor XA Inhibitor
|
US8563573B2
(en)
|
2007-11-02 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Azaindole derivatives as CFTR modulators
|
EP2118103B1
(en)
|
2006-11-03 |
2014-04-23 |
Vertex Pharmaceuticals Inc. |
Azaindole derivatives as cftr modulators
|
US7754739B2
(en)
|
2007-05-09 |
2010-07-13 |
Vertex Pharmaceuticals Incorporated |
Modulators of CFTR
|
MX2009006806A
(es)
|
2006-12-22 |
2009-08-27 |
Vertex Pharma |
Secado por rocio fluidizado.
|
WO2008083130A2
(en)
|
2006-12-26 |
2008-07-10 |
Dr. Reddy's Laboratories Limited |
Amorphous and crystalline form a of carvedilol phosphate
|
CN104447716A
(zh)
|
2007-05-09 |
2015-03-25 |
沃泰克斯药物股份有限公司 |
Cftr调节剂
|
ES2548292T3
(es)
|
2007-05-25 |
2015-10-15 |
Vertex Pharmaceuticals Incorporated |
Moduladores del regulador de la conductancia transmembrana de la fibrosis quística
|
US20110177999A1
(en)
|
2007-08-09 |
2011-07-21 |
Vertex Pharmaceuticals Incorporated |
Therapeutic Combinations Useful in Treating CFTR Related Diseases
|
WO2009038913A2
(en)
|
2007-08-24 |
2009-03-26 |
Vertex Pharmaceuticals Incorporated |
Isothiazolopyridinones useful for the treatment of (inter alia) cystic fibrosis
|
CN101821266B
(zh)
|
2007-09-14 |
2014-03-12 |
沃泰克斯药物股份有限公司 |
囊性纤维化跨膜通道调节因子的调节剂
|
NZ600865A
(en)
|
2007-09-14 |
2014-01-31 |
Vertex Pharma |
Solid forms of n-[2,4-bis(1,1-dimethylethyl)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
CA2705562C
(en)
|
2007-11-16 |
2016-05-17 |
Vertex Pharmaceuticals Incorporated |
Isoquinoline modulators of atp-binding cassette transporters
|
CA2989620C
(en)
|
2007-12-07 |
2022-05-03 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
|
WO2009076141A2
(en)
|
2007-12-07 |
2009-06-18 |
Vertex Pharmaceuticals Incorporated |
Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cycklopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
US20100036130A1
(en)
|
2007-12-07 |
2010-02-11 |
Vertex Pharmaceuticals Incorporated |
Processes for producing cycloalkylcarboxamido-pyridine benzoic acids
|
CN101910156B
(zh)
|
2007-12-07 |
2013-12-04 |
沃泰克斯药物股份有限公司 |
3-(6-(1-(2,2-二氟苯并[d][1,3]间二氧杂环戊烯-5-基)环丙烷甲酰氨基)-3-甲基吡啶-2-基)苯甲酸的固体形式
|
JP5637859B2
(ja)
|
2007-12-13 |
2014-12-10 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
嚢胞性線維症膜コンダクタンスレギュレーターのモジュレーター
|
EP2271622B1
(en)
|
2008-02-28 |
2017-10-04 |
Vertex Pharmaceuticals Incorporated |
Heteroaryl derivatives as CFTR Modulators
|
PT2615085E
(pt)
|
2008-03-31 |
2015-10-09 |
Vertex Pharma |
Derivados piridilo como moduladores cftr
|
US20100256184A1
(en)
|
2008-08-13 |
2010-10-07 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical composition and administrations thereof
|
JP5575768B2
(ja)
|
2008-08-13 |
2014-08-20 |
バーテックス ファーマシューティカルズ インコーポレイテッド |
薬学的組成物およびその投与
|
WO2010025126A1
(en)
|
2008-08-26 |
2010-03-04 |
Cystic Fibrosis Foundation Therapeutics, Inc. |
Rapidly disintegrating tablets comprising lipase, amylase, and protease
|
CN102164587A
(zh)
|
2008-09-29 |
2011-08-24 |
沃泰克斯药物股份有限公司 |
3-(6-(1-(2,2-二氟苯并[d][1,3]间二氧杂环戊烯-5-基)环丙烷甲酰氨基)-3-甲基吡啶-2-基)苯甲酸的剂量单元
|
JP5645834B2
(ja)
|
2008-10-23 |
2014-12-24 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
嚢胞性線維症膜コンダクタンス制御因子の修飾因子
|
US20110257223A1
(en)
|
2008-10-23 |
2011-10-20 |
Vertex Pharmaceuticals Incorporated |
Modulators of Cystic Fibrosis Transmembrane Conductance Regulator
|
EA018891B1
(ru)
|
2008-10-23 |
2013-11-29 |
Вертекс Фармасьютикалз, Инкорпорейтед |
Модуляторы регулятора трансмембранной проводимости при муковисцидозе
|
JP5645835B2
(ja)
|
2008-10-23 |
2014-12-24 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
N−(4−(7−アザビシクロ[2.2.1]ヘプタン−7−イル)−2−(トリフルオロメチル)フェニル)−4−オキソ−5−(トリフルオロメチル)−1,4−ジヒドロキノリン−3−カルボキサミドの固体形態
|
UA121188C2
(uk)
|
2008-11-06 |
2020-04-27 |
Вертекс Фармасьютікалз Інкорпорейтед |
Модулятори атф-зв'язувальних касетних транспортерів
|
UA104876C2
(uk)
|
2008-11-06 |
2014-03-25 |
Вертекс Фармасьютікалз Інкорпорейтед |
Модулятори atф-зв'язувальних касетних транспортерів
|
EP2382197B1
(en)
|
2008-12-30 |
2016-10-05 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
CA2755969C
(en)
|
2009-03-20 |
2018-05-08 |
Vertex Pharmaceuticals Incorporated |
Modulators of cystic fibrosis transmembrane conductance regulator
|
SG10201504084QA
(en)
|
2009-03-20 |
2015-06-29 |
Vertex Pharma |
Process for making modulators of cystic fibrosis transmembrane conductance regulator
|
KR20120083416A
(ko)
|
2009-09-17 |
2012-07-25 |
버텍스 파마슈티칼스 인코포레이티드 |
아자비시클릭 화합물의 제조 방법
|
EP2490687A1
(en)
|
2009-10-22 |
2012-08-29 |
Vertex Pharmaceuticals Incorporated |
Compositions for treatment of cystic fibrosis and other chronic diseases
|
CN102648182A
(zh)
|
2009-10-23 |
2012-08-22 |
沃泰克斯药物股份有限公司 |
用于制备囊性纤维化跨膜传导调节因子的调节剂的方法
|
CA2778493A1
(en)
|
2009-10-23 |
2011-04-28 |
Vertex Pharmaceuticals Incorporated |
Solid forms of n-(4-(7-azabicyclo[2.2.1]heptan-7-yl)-2-trifluoromethyl)phenyl)-4-oxo-5-(trifluoromethyl)-1,4-dihydroquinoline-3-carboxamide
|
CN103180298A
(zh)
|
2010-03-19 |
2013-06-26 |
沃泰克斯药物股份有限公司 |
N-[2,4-双(1,1-二甲基乙基)-5-羟基苯基]-1,4-二氢-4-氧代喹啉-3-甲酰胺的固体形式
|
US8802868B2
(en)
|
2010-03-25 |
2014-08-12 |
Vertex Pharmaceuticals Incorporated |
Solid forms of (R)-1(2,2-difluorobenzo[D][1,3]dioxo1-5-yl)-N-(1-(2,3-dihydroxypropyl-6-fluoro-2-(1-hydroxy-2-methylpropan2-yl)-1H-Indol-5-yl)-Cyclopropanecarboxamide
|
PT2826776T
(pt)
|
2010-03-25 |
2021-02-01 |
Vertex Pharma |
Forma amorfa sólida de (r)-1(2,2-difluorobenzo(d)(1,3)dioxol-5-ilo)-n-(1-(2,3-dihidroxipropilo)-6-fluoro-2-(1-hidroxi-2-metilpropan-2-ilo)-1h-indol-5-ilo)-ciclopropanocarboxamida
|
DK3150198T3
(da)
|
2010-04-07 |
2021-11-01 |
Vertex Pharma |
Farmaceutiske sammensætninger af 3-(6-(1-(2,2-difluorbenzo[d][1,3]dioxol-5-yl)-cyclopropancarboxamido)-3-methylpyriodin-2-yl)benzoesyre og indgivelse deraf
|
BR112012026257A2
(pt)
|
2010-04-07 |
2017-03-14 |
Vertex Pharma |
formas sólidas de ácido 3-(6-(1-(2-,2-difluorbenzo[d][1,3]dioxol-5-il)ciclopropanocarboxamido)-3-metilpiridin-2-il)benzóico
|
EP2560651A1
(en)
|
2010-04-22 |
2013-02-27 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
EP2560649A1
(en)
|
2010-04-22 |
2013-02-27 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
NZ603043A
(en)
|
2010-04-22 |
2015-02-27 |
Vertex Pharma |
Pharmaceutical compositions comprising cftr modulators and administrations thereof
|
MX2012012204A
(es)
|
2010-04-22 |
2012-12-05 |
Vertex Pharma |
Proceso para producir compuestos de cicloalquilcarboxamido-indol.
|
AU2011255237A1
(en)
|
2010-05-20 |
2012-11-29 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions and administrations thereof
|
US8404849B2
(en)
|
2010-05-20 |
2013-03-26 |
Vertex Pharmaceuticals |
Processes for producing modulators of cystic fibrosis transmembrane conductance regulator
|
US8563593B2
(en)
|
2010-06-08 |
2013-10-22 |
Vertex Pharmaceuticals Incorporated |
Formulations of (R)-1-(2,2-difluorobenzo[D] [1,3] dioxol-5-yl)-N-(1-(2,3-dihydroxypropyl)-6-fluoro-2-(1-hydroxy-2-methylpropan-2-yl)-1H-indol-5-yl)cyclopropanecarboxamide
|
WO2011163614A2
(en)
|
2010-06-24 |
2011-12-29 |
Meritage Pharma, Inc. |
Methods of treatment for esophageal inflammation
|
MX2013002035A
(es)
|
2010-08-23 |
2013-03-25 |
Vertex Pharma |
Composiciones farmaceuticas de (r)-1-(2, 2-difluorobenzo[d] [1, 3]dioxol-5-il)-n-(1-(2, 3-dihidroxipropil)-6-fluoro-2-(1-hidroxi-2 -metilpropano-2-il)-1h-indol-5-il) ciclopropanocarboxamida y administracion de las mismas.
|
RU2013113627A
(ru)
|
2010-08-27 |
2014-10-10 |
Вертекс Фармасьютикалз Инкорпорейтед |
Фармацевтическая композиция и ее введения
|
US8802700B2
(en)
|
2010-12-10 |
2014-08-12 |
Vertex Pharmaceuticals Incorporated |
Modulators of ATP-Binding Cassette transporters
|
AR086745A1
(es)
|
2011-06-27 |
2014-01-22 |
Parion Sciences Inc |
3,5-diamino-6-cloro-n-(n-(4-(4-(2-(hexil(2,3,4,5,6-pentahidroxihexil)amino)etoxi)fenil)butil)carbamimidoil)pirazina-2-carboxamida
|
AU2012332225A1
(en)
|
2011-11-02 |
2014-05-15 |
Vertex Pharmaceuticals Incorporated |
Use of (N- [2, 4 -bis (1, 1 -dimethylethyl) - 5 - hydroxyphenyl] - 1, 4 - dihydro - 4 - oxoquinoline - 3 - ca rboxamide) for treating CFTR mediated diseases
|
US20140127901A1
(en)
|
2012-11-08 |
2014-05-08 |
Taiwan Semiconductor Manufacturing Company, Ltd. |
Low-k damage free integration scheme for copper interconnects
|
ME02650B
(me)
|
2011-11-08 |
2017-06-20 |
Vertex Pharma |
Modulatori atp- vezujućih kasetnih transportera
|
CA2862859C
(en)
|
2012-01-25 |
2022-08-02 |
Vertex Pharmaceuticals Incorporated |
Formulations of 3-(6-(1-(2,2-difluorobenzo[d][1,3]dioxol-5-yl) cyclopropanecarboxamido)-3-methylpyridin-2-yl)benzoic acid
|
CN109966264A
(zh)
|
2012-02-27 |
2019-07-05 |
沃泰克斯药物股份有限公司 |
药物组合物及其施用
|
US8674108B2
(en)
|
2012-04-20 |
2014-03-18 |
Vertex Pharmaceuticals Incorporated |
Solid forms of N-[2,4-bis(1,1-dimethylethy)-5-hydroxyphenyl]-1,4-dihydro-4-oxoquinoline-3-carboxamide
|
AU2013270681A1
(en)
|
2012-06-08 |
2014-12-18 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions for the treatment of CFTR -mediated disorders
|
AR092857A1
(es)
|
2012-07-16 |
2015-05-06 |
Vertex Pharma |
Composiciones farmaceuticas de (r)-1-(2,2-difluorobenzo[d][1,3]dioxol-5-il)-n-(1-(2,3-dihidroxipropil)-6-fluoro-2-(1-hidroxi-2-metilpropan-2-il)-1h-indol-5-il)ciclopropancarboxamida y administracion de las mismas
|
IL283276B2
(en)
|
2012-11-02 |
2024-05-01 |
Vertex Pharma |
Preparations containing 3-(6-(1-(2,2-difluorobenzo[1,3][D]dioxol-5-yl)cycloproponecarboxamide)-3-methylpyridin-2-yl)benzoic acid and N-(5-hydroxy- 2,4-di-tert-butyl-phenyl)-4-oxo-H1-quinoline-3-carboxamide and their uses
|
US20140221424A1
(en)
|
2013-01-30 |
2014-08-07 |
Vertex Pharmaceuticals Incorporated |
Pharmaceutical compositions for use in the treatment of cystic fibrosis
|
US10231932B2
(en)
|
2013-11-12 |
2019-03-19 |
Vertex Pharmaceuticals Incorporated |
Process of preparing pharmaceutical compositions for the treatment of CFTR mediated diseases
|
ES2957761T3
(es)
|
2014-04-15 |
2024-01-25 |
Vertex Pharma |
Composiciones farmacéuticas para el tratamiento de enfermedades mediadas por el regulador de la conductancia transmembrana de fibrosis quística
|
SG10201913603QA
(en)
|
2014-10-06 |
2020-02-27 |
Vertex Pharma |
Modulators of cystic fibrosis transmembrane conductance regulator
|
CN107250113B
(zh)
|
2014-10-07 |
2019-03-29 |
弗特克斯药品有限公司 |
囊性纤维化跨膜传导调节蛋白的调节剂的共晶
|
JP6494757B2
(ja)
|
2014-11-18 |
2019-04-03 |
バーテックス ファーマシューティカルズ インコーポレイテッドVertex Pharmaceuticals Incorporated |
ハイスループット試験高速液体クロマトグラフィーを行うプロセス
|
MA41031A
(fr)
|
2014-11-26 |
2017-10-03 |
Catabasis Pharmaceuticals Inc |
Conjugués cystéamine-acide gras et leur utilisation comme activateurs de l'autophagie
|
WO2016086136A1
(en)
|
2014-11-26 |
2016-06-02 |
Catabasis Pharmaceuticals, Inc. |
Fatty acid cysteamine conjugates of cftr modulators and their use in treating medical disorders
|
CA2969587A1
(en)
|
2014-12-05 |
2016-06-09 |
Centre National De La Recherche Scientifique (Cnrs) |
Compounds for treating cystic fibrosis
|
US9957234B2
(en)
|
2014-12-09 |
2018-05-01 |
Laurus Labs Limited |
Polymorphs of Ivacaftor, process for its preparation and pharmaceutical composition thereof
|
CA2981495C
(en)
|
2015-03-31 |
2023-09-26 |
Vertex Pharmaceuticals (Europe) Limited |
Deuterated vx-661
|
GB201507926D0
(en)
|
2015-05-08 |
2015-06-24 |
Proqr Therapeutics N V |
Improved treatments using oligonucleotides
|
US10336703B2
(en)
|
2015-05-12 |
2019-07-02 |
Council Of Scientific And Industrial Research |
Process for the synthesis of ivacaftor and related compounds
|
UY36680A
(es)
|
2015-05-19 |
2016-12-30 |
Glaxosmithkline Ip Dev Ltd |
Amidas heterocíclicas como inhibidores de quinasa
|
CA3021752A1
(en)
|
2015-06-11 |
2016-12-15 |
Aizant Drug Research Solutions Private Limited |
Nanoparticulate ivacaftor formulations
|
CN105884628B
(zh)
|
2016-06-06 |
2018-06-29 |
上海工程技术大学 |
2,4-二叔丁基-5-氨基酚的制备方法
|
WO2018183367A1
(en)
|
2017-03-28 |
2018-10-04 |
Van Goor Fredrick F |
Methods of treating cystic fibrosis in patients with residual function mutations
|