DK174999B1 - Pyrrolderivater - Google Patents

Pyrrolderivater Download PDF

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Publication number
DK174999B1
DK174999B1 DK198800143A DK14388A DK174999B1 DK 174999 B1 DK174999 B1 DK 174999B1 DK 198800143 A DK198800143 A DK 198800143A DK 14388 A DK14388 A DK 14388A DK 174999 B1 DK174999 B1 DK 174999B1
Authority
DK
Denmark
Prior art keywords
pyrrole
solution
pyrrolo
added
lower alkyl
Prior art date
Application number
DK198800143A
Other languages
Danish (da)
English (en)
Other versions
DK14388A (da
DK14388D0 (da
Inventor
Hiralal N Khatri
Michael P Fleming
George C Schloemer
Original Assignee
Syntex Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/003,104 external-priority patent/US4849526A/en
Priority claimed from US07/003,162 external-priority patent/US4835288A/en
Application filed by Syntex Inc filed Critical Syntex Inc
Publication of DK14388D0 publication Critical patent/DK14388D0/da
Publication of DK14388A publication Critical patent/DK14388A/da
Application granted granted Critical
Publication of DK174999B1 publication Critical patent/DK174999B1/da

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/18—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D207/22—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D207/00—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D207/02—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D207/30—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members
    • C07D207/34—Heterocyclic compounds containing five-membered rings not condensed with other rings, with one nitrogen atom as the only ring hetero atom with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pain & Pain Management (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
DK198800143A 1987-01-14 1988-01-13 Pyrrolderivater DK174999B1 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US07/003,104 US4849526A (en) 1987-01-14 1987-01-14 Process for preparing (±)-2,3-dihydro-1H-pyrrolo[1,2-A]pyrrole-1,7-dicarboxylates
US07/003,162 US4835288A (en) 1987-01-14 1987-01-14 Process for preparing (+)-2,3-dihydro-1H-pyrrolo[1,2-a]pyrrole-1,7-dicarboxylates
US316287 1987-01-14
US310487 1987-01-14

Publications (3)

Publication Number Publication Date
DK14388D0 DK14388D0 (da) 1988-01-13
DK14388A DK14388A (da) 1988-07-15
DK174999B1 true DK174999B1 (da) 2004-04-13

Family

ID=26671322

Family Applications (2)

Application Number Title Priority Date Filing Date
DK198800143A DK174999B1 (da) 1987-01-14 1988-01-13 Pyrrolderivater
DK200000691A DK175516B1 (da) 1987-01-14 2000-04-27 Fremgangsmåde til fremstilling af pyrrolderivater

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK200000691A DK175516B1 (da) 1987-01-14 2000-04-27 Fremgangsmåde til fremstilling af pyrrolderivater

Country Status (16)

Country Link
EP (1) EP0275092B1 (fr)
JP (1) JP2665342B2 (fr)
KR (1) KR960001475B1 (fr)
AU (1) AU613334B2 (fr)
CA (1) CA1340404C (fr)
DE (1) DE3871533T2 (fr)
DK (2) DK174999B1 (fr)
ES (1) ES2041703T3 (fr)
FI (1) FI90344C (fr)
GR (1) GR3004788T3 (fr)
HK (1) HK39097A (fr)
HU (8) HU198927B (fr)
IE (1) IE62987B1 (fr)
IL (1) IL85094A (fr)
NO (1) NO169124C (fr)
NZ (1) NZ223175A (fr)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR0140134B1 (ko) * 1994-11-16 1998-06-01 강재헌 피롤리진 유도체의 제조방법
CN112898307A (zh) * 2021-02-07 2021-06-04 贵州省中国科学院天然产物化学重点实验室(贵州医科大学天然产物化学重点实验室) 一种酮咯酸杂质c及其制备方法与应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4089969A (en) * 1976-07-14 1978-05-16 Syntex (U.S.A.) Inc. 5-Aroyl-1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic acid derivatives and process for the production thereof
JPS539789A (en) * 1976-07-14 1978-01-28 Syntex Inc Production of 55*22floyl** * 55*22thenoyl** * 55*33 floyl** and 55*33thenoyl** 1*22dihydroo3hhpyroro * 1*22a*pyrolee11carboxylic acid derivative
US4097579A (en) * 1977-03-31 1978-06-27 Syntex (U.S.A.) Inc. 5-(2-Pyrroyl)-1,2-dihydro-3H-pyrrolo 1,2-a!pyrrole-1-carboxylic acid derivatives and process for the production thereof
US4344943A (en) * 1980-06-09 1982-08-17 Syntex (U.S.A.) Inc. 6-Chloro- or 6-bromo-1,2-dihydro-3H-pyrrolo[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof
US4353829A (en) * 1980-11-21 1982-10-12 Syntex (U.S.A.) Inc. Process for 5-aroylation of 1,2-dihydro-3H-pyrrolo[1,2-a]pyrrole-1-carboxylic esters
US4560699A (en) * 1983-01-17 1985-12-24 Syntex (U.S.A.) Inc. 5-(4-Vinylbenzoyl)-1,2-dihydro-3H-pyrrolo-[1,2-a]-pyrrole-1-carboxylic acids and derivatives thereof and use as analgesics and anti-inflammatories

Also Published As

Publication number Publication date
HU895354D0 (en) 1990-01-28
EP0275092A1 (fr) 1988-07-20
NO880127L (no) 1988-07-15
DE3871533T2 (de) 1992-12-10
ES2041703T3 (es) 1993-12-01
DK14388A (da) 1988-07-15
JPS63198684A (ja) 1988-08-17
AU1024088A (en) 1988-07-21
KR880009022A (ko) 1988-09-13
IL85094A0 (en) 1988-06-30
NZ223175A (en) 1992-08-26
HU203532B (en) 1991-08-28
HK39097A (en) 1997-04-04
HUT52046A (en) 1990-06-28
NO880127D0 (no) 1988-01-13
DE3871533D1 (de) 1992-07-09
NO169124B (no) 1992-02-03
FI880133A (fi) 1988-07-15
CA1340404C (fr) 1999-02-23
IE62987B1 (en) 1995-03-08
KR960001475B1 (ko) 1996-01-31
JP2665342B2 (ja) 1997-10-22
HU201728B (en) 1990-12-28
IE880083L (en) 1988-07-14
HUT51595A (en) 1990-05-28
DK200000691A (da) 2000-04-27
HU203721B (en) 1991-09-30
HU198927B (en) 1989-12-28
HUT48881A (en) 1989-07-28
FI880133A0 (fi) 1988-01-13
DK14388D0 (da) 1988-01-13
HU200606B (en) 1990-07-28
GR3004788T3 (fr) 1993-04-28
FI90344B (fi) 1993-10-15
DK175516B1 (da) 2004-11-15
FI90344C (fi) 1994-01-25
EP0275092B1 (fr) 1992-06-03
HU895356D0 (en) 1990-01-28
HU895355D0 (en) 1990-01-28
IL85094A (en) 1991-09-16
AU613334B2 (en) 1991-08-01
HUT52045A (en) 1990-06-28
NO169124C (no) 1992-05-13

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