DK171454B1 - Fremgangsmåde til fremstilling af tørforarbejdede partikler, således opnåede tørforarbejdede partikler, og præparater indeholdende sådanne partikler - Google Patents

Fremgangsmåde til fremstilling af tørforarbejdede partikler, således opnåede tørforarbejdede partikler, og præparater indeholdende sådanne partikler Download PDF

Info

Publication number
DK171454B1
DK171454B1 DK054994A DK54994A DK171454B1 DK 171454 B1 DK171454 B1 DK 171454B1 DK 054994 A DK054994 A DK 054994A DK 54994 A DK54994 A DK 54994A DK 171454 B1 DK171454 B1 DK 171454B1
Authority
DK
Denmark
Prior art keywords
biocompatible polymer
stirring
active ingredient
particles
support phase
Prior art date
Application number
DK054994A
Other languages
Danish (da)
English (en)
Other versions
DK54994A (da
Inventor
Jean-Marc Ruiz
Original Assignee
Scras
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scras filed Critical Scras
Publication of DK54994A publication Critical patent/DK54994A/da
Application granted granted Critical
Publication of DK171454B1 publication Critical patent/DK171454B1/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
DK054994A 1993-05-15 1994-05-13 Fremgangsmåde til fremstilling af tørforarbejdede partikler, således opnåede tørforarbejdede partikler, og præparater indeholdende sådanne partikler DK171454B1 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9310030 1993-05-15
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (2)

Publication Number Publication Date
DK54994A DK54994A (da) 1994-11-16
DK171454B1 true DK171454B1 (da) 1996-11-04

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
DK054994A DK171454B1 (da) 1993-05-15 1994-05-13 Fremgangsmåde til fremstilling af tørforarbejdede partikler, således opnåede tørforarbejdede partikler, og præparater indeholdende sådanne partikler

Country Status (35)

Country Link
JP (1) JP3139913B2 (ru)
KR (1) KR100341261B1 (ru)
CN (1) CN1050534C (ru)
AT (1) AT406017B (ru)
AU (1) AU685094B2 (ru)
BE (1) BE1008323A3 (ru)
BR (1) BR9401968A (ru)
CA (1) CA2123481C (ru)
CH (1) CH688572A5 (ru)
DE (1) DE4416812C2 (ru)
DK (1) DK171454B1 (ru)
DZ (1) DZ1779A1 (ru)
ES (1) ES2097083B1 (ru)
FI (1) FI112915B (ru)
FR (1) FR2705232B1 (ru)
GB (2) GB9310030D0 (ru)
GR (1) GR1002034B (ru)
HK (1) HK1002831A1 (ru)
HU (1) HU220617B1 (ru)
IE (1) IE940392A1 (ru)
IN (1) IN182330B (ru)
IT (1) IT1269508B (ru)
LU (1) LU88482A1 (ru)
MA (1) MA23194A1 (ru)
NL (1) NL9400795A (ru)
NO (1) NO307403B1 (ru)
NZ (1) NZ260520A (ru)
OA (1) OA09939A (ru)
PL (1) PL175780B1 (ru)
PT (1) PT101518B (ru)
RU (1) RU2125869C1 (ru)
SE (1) SE519004C2 (ru)
SG (1) SG46631A1 (ru)
TN (1) TNSN94046A1 (ru)
ZA (1) ZA943316B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU220137B (hu) * 1993-01-06 2001-11-28 Kinerton Ltd. Biológiailag lebontható poliészterek és biológiailag aktív polipeptidek ionos molekuláris konjugátumai, eljárás ezek előállítására és eljárás mikrorészecskék előállítására
DE69435055T2 (de) * 1993-01-06 2008-12-04 IPSEN Manufacturing Ireland Ltd., Blanchardstown Bioabbaubare Polyester zur Herstellung ionischer molekularer Konjugate mit bioaktiven Polypeptiden
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
CA2685349C (en) 1999-11-15 2013-09-17 Bio Syntech Canada Inc. Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
US6646083B2 (en) 2000-06-16 2003-11-11 Nippon Shokubai Co., Ltd. Crosslinked polymers containing tertiary amine and/or quaternary ammonium salt structures, processes for making and uses thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (ru) * 1987-10-14 1990-01-15 Debiopharm Sa
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
DE69123075T2 (de) * 1990-04-12 1997-03-20 Shionogi Seiyaku Kk Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung
JP3116311B2 (ja) * 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE9101603L (sv) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm Metod foer att framstaella reproducerbara partiklar av definierad storlek
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
JPH07507768A (ja) * 1992-03-12 1995-08-31 アルカーメス　コントロールド　セラピューティクス，インコーポレイテッド Ａｃｔｈ含有マイクロスフェアの制御放出
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
ATE222500T1 (de) * 1992-06-11 2002-09-15 Alkermes Inc Enythropoietin enthaltendes arzneimittelabgabesystem
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
TNSN94046A1 (fr) 1995-04-25
JPH072652A (ja) 1995-01-06
DK54994A (da) 1994-11-16
SG46631A1 (en) 1998-02-20
NO941810L (no) 1994-11-16
BE1008323A3 (fr) 1996-04-02
CN1050534C (zh) 2000-03-22
PT101518B (pt) 2000-12-29
IT1269508B (it) 1997-04-01
SE9401557D0 (sv) 1994-05-05
BR9401968A (pt) 1994-12-13
RU2125869C1 (ru) 1999-02-10
LU88482A1 (fr) 1994-12-01
GB9409565D0 (en) 1994-07-06
IN182330B (ru) 1999-03-20
FR2705232A1 (fr) 1994-11-25
GB2277915B (en) 1997-10-29
FI112915B (fi) 2004-02-13
SE519004C2 (sv) 2002-12-17
GB9310030D0 (en) 1993-06-30
JP3139913B2 (ja) 2001-03-05
ITMI940931A0 (it) 1994-05-11
OA09939A (fr) 1994-11-15
FI942222A0 (fi) 1994-05-13
HK1002831A1 (en) 1998-09-18
KR100341261B1 (ko) 2002-09-27
ATA98794A (de) 1999-06-15
NO941810D0 (no) 1994-05-13
CN1104557A (zh) 1995-07-05
ITMI940931A1 (it) 1995-11-11
HU220617B1 (hu) 2002-03-28
AT406017B (de) 2000-01-25
AU6308494A (en) 1994-11-17
ES2097083B1 (es) 1997-12-01
SE9401557L (sv) 1994-11-16
NO307403B1 (no) 2000-04-03
DE4416812A1 (de) 1994-11-17
NL9400795A (nl) 1994-12-01
GB2277915A (en) 1994-11-16
DE4416812C2 (de) 2003-02-06
GR1002034B (en) 1995-10-31
ES2097083A1 (es) 1997-03-16
FR2705232B1 (fr) 1995-08-25
FI942222A (fi) 1994-11-16
CA2123481A1 (en) 1994-11-16
PT101518A (pt) 1995-03-01
CH688572A5 (fr) 1997-11-28
PL175780B1 (pl) 1999-02-26
AU685094B2 (en) 1998-01-15
ZA943316B (en) 1995-01-16
MA23194A1 (fr) 1994-12-31
DZ1779A1 (fr) 2002-02-17
NZ260520A (en) 1994-12-22
CA2123481C (en) 2005-01-11
HUT67599A (en) 1995-04-28
IE940392A1 (en) 1994-11-16
HU9401412D0 (en) 1994-08-29

Similar Documents

Publication Publication Date Title
JP2818704B2 (ja) 徐放性組成物およびその製造方法
CA2040141C (en) Biodegradable high-molecular polymers, production and use therof
EP0442671B1 (en) Prolonged release microcapsules
JP2651320B2 (ja) 徐放性マイクロスフェア製剤の製造方法
JP3600252B2 (ja) 医薬物質を持続的に制御して放出できる組成物
EP1248596B1 (de) Kit zur implantation enthaltend eine trägerphase und ein lösungsmittel
US20180177785A1 (en) Method of Making Sustained Release Microparticles
DE102005047561A1 (de) Feste, oral applizierbare pharmazeutische Darreichungsformen mit schneller Wirkstofffreisetzung
US5569467A (en) Process for the preparation of microballs and microballs thus obtained
PL212531B1 (pl) Kompozycja o przedluzonym uwalnianiu leuproreliny, sposób wytwarzania kompozycji, srodek farmaceutyczny zawierajacy kompozycje i zastosowanie kompozycji, sposób wytwarzania polimeru kwasu mlekowego i kwasu glikolowego i zastosowanie polimeru
DK171454B1 (da) Fremgangsmåde til fremstilling af tørforarbejdede partikler, således opnåede tørforarbejdede partikler, og præparater indeholdende sådanne partikler
JP2526589B2 (ja) ペプチド含有マイクロカプセルおよびその製造法
KR20220112737A (ko) 리바스티그민을 포함하는 장기지속형 제제 및 이의 제조방법
JP2023506175A (ja) カリプラジン放出製剤
KR102185348B1 (ko) 데슬로렐린을 함유하는 서방형 주사제 및 그 제조방법
PT996426E (pt) Sistema multifásico
KR20160019022A (ko) 생분해성 필러용 미립자의 제조 방법
JPS6341416A (ja) 鎮痛性ペプチド含有マイクロカプセルの製造法
JP2003192595A (ja) 局所投与剤

Legal Events

Date Code Title Description
B1 Patent granted (law 1993)
PBP Patent lapsed

Country of ref document: DK