SE519004C2 - Förfarande för framställning av torrbehandlade partiklar, torrbehandlade partiklar som erhålles på detta sätt och farmaceutiska kompositioner som innehåller sådana partiklar - Google Patents

Förfarande för framställning av torrbehandlade partiklar, torrbehandlade partiklar som erhålles på detta sätt och farmaceutiska kompositioner som innehåller sådana partiklar

Info

Publication number
SE519004C2
SE519004C2 SE9401557A SE9401557A SE519004C2 SE 519004 C2 SE519004 C2 SE 519004C2 SE 9401557 A SE9401557 A SE 9401557A SE 9401557 A SE9401557 A SE 9401557A SE 519004 C2 SE519004 C2 SE 519004C2
Authority
SE
Sweden
Prior art keywords
particles
active ingredient
polymer
stirring
biocompatible polymer
Prior art date
Application number
SE9401557A
Other languages
English (en)
Swedish (sv)
Other versions
SE9401557D0 (sv
SE9401557L (sv
Inventor
Jean-Marc Ruiz
Original Assignee
Sod Conseils Rech Applic
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sod Conseils Rech Applic filed Critical Sod Conseils Rech Applic
Publication of SE9401557D0 publication Critical patent/SE9401557D0/xx
Publication of SE9401557L publication Critical patent/SE9401557L/
Publication of SE519004C2 publication Critical patent/SE519004C2/sv

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
SE9401557A 1993-05-15 1994-05-05 Förfarande för framställning av torrbehandlade partiklar, torrbehandlade partiklar som erhålles på detta sätt och farmaceutiska kompositioner som innehåller sådana partiklar SE519004C2 (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (3)

Publication Number Publication Date
SE9401557D0 SE9401557D0 (sv) 1994-05-05
SE9401557L SE9401557L (sv) 1994-11-16
SE519004C2 true SE519004C2 (sv) 2002-12-17

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
SE9401557A SE519004C2 (sv) 1993-05-15 1994-05-05 Förfarande för framställning av torrbehandlade partiklar, torrbehandlade partiklar som erhålles på detta sätt och farmaceutiska kompositioner som innehåller sådana partiklar

Country Status (35)

Country Link
JP (1) JP3139913B2 (ru)
KR (1) KR100341261B1 (ru)
CN (1) CN1050534C (ru)
AT (1) AT406017B (ru)
AU (1) AU685094B2 (ru)
BE (1) BE1008323A3 (ru)
BR (1) BR9401968A (ru)
CA (1) CA2123481C (ru)
CH (1) CH688572A5 (ru)
DE (1) DE4416812C2 (ru)
DK (1) DK171454B1 (ru)
DZ (1) DZ1779A1 (ru)
ES (1) ES2097083B1 (ru)
FI (1) FI112915B (ru)
FR (1) FR2705232B1 (ru)
GB (2) GB9310030D0 (ru)
GR (1) GR1002034B (ru)
HK (1) HK1002831A1 (ru)
HU (1) HU220617B1 (ru)
IE (1) IE940392A1 (ru)
IN (1) IN182330B (ru)
IT (1) IT1269508B (ru)
LU (1) LU88482A1 (ru)
MA (1) MA23194A1 (ru)
NL (1) NL9400795A (ru)
NO (1) NO307403B1 (ru)
NZ (1) NZ260520A (ru)
OA (1) OA09939A (ru)
PL (1) PL175780B1 (ru)
PT (1) PT101518B (ru)
RU (1) RU2125869C1 (ru)
SE (1) SE519004C2 (ru)
SG (1) SG46631A1 (ru)
TN (1) TNSN94046A1 (ru)
ZA (1) ZA943316B (ru)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU220137B (hu) * 1993-01-06 2001-11-28 Kinerton Ltd. Biológiailag lebontható poliészterek és biológiailag aktív polipeptidek ionos molekuláris konjugátumai, eljárás ezek előállítására és eljárás mikrorészecskék előállítására
DE69435055T2 (de) * 1993-01-06 2008-12-04 IPSEN Manufacturing Ireland Ltd., Blanchardstown Bioabbaubare Polyester zur Herstellung ionischer molekularer Konjugate mit bioaktiven Polypeptiden
DE19604744A1 (de) 1996-02-09 1997-08-14 Henkel Kgaa Technische Di-/Triglyceridgemische
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (de) * 1996-04-29 1997-02-27 Henkel Kgaa Verwendung von Copolymerestern für die Herstellung von Mikrosphären
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
CA2685349C (en) 1999-11-15 2013-09-17 Bio Syntech Canada Inc. Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
US6646083B2 (en) 2000-06-16 2003-11-11 Nippon Shokubai Co., Ltd. Crosslinked polymers containing tertiary amine and/or quaternary ammonium salt structures, processes for making and uses thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (ru) * 1987-10-14 1990-01-15 Debiopharm Sa
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (de) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retardierende Mikropartikel aus bioabbaubaren Polyestern; Verfahren zu deren Herstellung unter Verzicht auf toxische Lösungsmittel und diese Mikropartikel enthaltende pharmazentische Zubereitungen
DE69123075T2 (de) * 1990-04-12 1997-03-20 Shionogi Seiyaku Kk Ueberzogene Zusammensetzung sowie Verfahren zu ihrer Herstellung
JP3116311B2 (ja) * 1990-06-13 2000-12-11 エーザイ株式会社 マイクロスフィアの製法
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (sv) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab Foerfarande foer att formulera laekemedel
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE9101603L (sv) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm Metod foer att framstaella reproducerbara partiklar av definierad storlek
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
JPH07507768A (ja) * 1992-03-12 1995-08-31 アルカーメス　コントロールド　セラピューティクス，インコーポレイテッド Ａｃｔｈ含有マイクロスフェアの制御放出
SE9200858L (sv) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Metod för framställning av pellets med fördröjd frisättning
ATE222500T1 (de) * 1992-06-11 2002-09-15 Alkermes Inc Enythropoietin enthaltendes arzneimittelabgabesystem
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (ja) * 1992-07-16 1997-09-10 田辺製薬株式会社 徐放性マイクロスフェア製剤の製造方法
FR2693905B1 (fr) * 1992-07-27 1994-09-02 Rhone Merieux Procédé de préparation de microsphères pour la libération prolongée de l'hormone LHRH et ses analogues, microsphères et formulations obtenues.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
TNSN94046A1 (fr) 1995-04-25
JPH072652A (ja) 1995-01-06
DK54994A (da) 1994-11-16
SG46631A1 (en) 1998-02-20
NO941810L (no) 1994-11-16
BE1008323A3 (fr) 1996-04-02
CN1050534C (zh) 2000-03-22
PT101518B (pt) 2000-12-29
IT1269508B (it) 1997-04-01
SE9401557D0 (sv) 1994-05-05
BR9401968A (pt) 1994-12-13
RU2125869C1 (ru) 1999-02-10
LU88482A1 (fr) 1994-12-01
GB9409565D0 (en) 1994-07-06
IN182330B (ru) 1999-03-20
FR2705232A1 (fr) 1994-11-25
GB2277915B (en) 1997-10-29
FI112915B (fi) 2004-02-13
GB9310030D0 (en) 1993-06-30
JP3139913B2 (ja) 2001-03-05
ITMI940931A0 (it) 1994-05-11
OA09939A (fr) 1994-11-15
FI942222A0 (fi) 1994-05-13
HK1002831A1 (en) 1998-09-18
KR100341261B1 (ko) 2002-09-27
ATA98794A (de) 1999-06-15
NO941810D0 (no) 1994-05-13
CN1104557A (zh) 1995-07-05
ITMI940931A1 (it) 1995-11-11
HU220617B1 (hu) 2002-03-28
DK171454B1 (da) 1996-11-04
AT406017B (de) 2000-01-25
AU6308494A (en) 1994-11-17
ES2097083B1 (es) 1997-12-01
SE9401557L (sv) 1994-11-16
NO307403B1 (no) 2000-04-03
DE4416812A1 (de) 1994-11-17
NL9400795A (nl) 1994-12-01
GB2277915A (en) 1994-11-16
DE4416812C2 (de) 2003-02-06
GR1002034B (en) 1995-10-31
ES2097083A1 (es) 1997-03-16
FR2705232B1 (fr) 1995-08-25
FI942222A (fi) 1994-11-16
CA2123481A1 (en) 1994-11-16
PT101518A (pt) 1995-03-01
CH688572A5 (fr) 1997-11-28
PL175780B1 (pl) 1999-02-26
AU685094B2 (en) 1998-01-15
ZA943316B (en) 1995-01-16
MA23194A1 (fr) 1994-12-31
DZ1779A1 (fr) 2002-02-17
NZ260520A (en) 1994-12-22
CA2123481C (en) 2005-01-11
HUT67599A (en) 1995-04-28
IE940392A1 (en) 1994-11-16
HU9401412D0 (en) 1994-08-29

Similar Documents

Publication Publication Date Title
US6692770B2 (en) Starch microparticles
EP1343480B2 (en) Induced phase transition method for the production of microparticles containing hydrophobic active agents
KR100442931B1 (ko) 수용성 펩티드의 서방성 제제 및 그의 제조방법
JPH05178740A (ja) 徐放性組成物およびその製造方法
US5569467A (en) Process for the preparation of microballs and microballs thus obtained
JP2003534267A (ja) 注射による投与のための持続放出微小球と調製手順
AU2001294458B2 (en) Biodegradable microparticles for controlled release administration, with purified amylopectin-based starch of reduced molecular weight
JPH0632732A (ja) 徐放性マイクロスフェア製剤の製造方法
WO1993011749A1 (en) A process for the preparation of a solid dispersion
JP2004510730A (ja) 非経口的投与可能な制御放出微粒子調製物
SE519004C2 (sv) Förfarande för framställning av torrbehandlade partiklar, torrbehandlade partiklar som erhålles på detta sätt och farmaceutiska kompositioner som innehåller sådana partiklar
JP2526589B2 (ja) ペプチド含有マイクロカプセルおよびその製造法
US7105181B2 (en) Microparticles
EP0934353B1 (en) Method for preparation of polymer microparticles free of organic solvent traces
Yu Comparison of protein loaded poly (?-caprolactone) microparticles prepared by the hot-melt technique
JPH08225454A (ja) マイクロスフェア製剤
WO2002058671A1 (en) Burst free pharmaceutical microparticules
JPS6341416A (ja) 鎮痛性ペプチド含有マイクロカプセルの製造法
JPH09208494A (ja) 微粒子製剤
Péan et al. from PLGA Biodegradable

Legal Events

Date Code Title Description
NUG Patent has lapsed