AU6308494A - Process for the preparation of microballs and microballs thus obtained - Google Patents

Process for the preparation of microballs and microballs thus obtained

Info

Publication number
AU6308494A
AU6308494A AU63084/94A AU6308494A AU6308494A AU 6308494 A AU6308494 A AU 6308494A AU 63084/94 A AU63084/94 A AU 63084/94A AU 6308494 A AU6308494 A AU 6308494A AU 6308494 A AU6308494 A AU 6308494A
Authority
AU
Australia
Prior art keywords
microballs
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
AU63084/94A
Other versions
AU685094B2 (en
Inventor
Jean-Marc Ruiz
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Ipsen Pharma SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ipsen Pharma SAS filed Critical Ipsen Pharma SAS
Publication of AU6308494A publication Critical patent/AU6308494A/en
Application granted granted Critical
Publication of AU685094B2 publication Critical patent/AU685094B2/en
Assigned to IPSEN PHARMA S.A.S reassignment IPSEN PHARMA S.A.S Request to Amend Deed and Register Assignors: SOCIETE DE CONSEILS DE RECHERCHES ET D'APPLICATIONS SCIENTIFIQUES (S.C.R.A.S.)
Anticipated expiration legal-status Critical
Ceased legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605—Excipients; Inactive ingredients
    • A61K9/1629—Organic macromolecular compounds
    • A61K9/1641—Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647—Polyesters, e.g. poly(lactide-co-glycolide)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682—Processes
    • A61K9/1694—Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient

Landscapes

  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Manufacturing Of Micro-Capsules (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Materials For Medical Uses (AREA)
AU63084/94A 1993-05-15 1994-05-13 Process for the preparation of microballs and microballs thus obtained Ceased AU685094B2 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same
GB9310030 1993-05-15

Publications (2)

Publication Number Publication Date
AU6308494A true AU6308494A (en) 1994-11-17
AU685094B2 AU685094B2 (en) 1998-01-15

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
AU63084/94A Ceased AU685094B2 (en) 1993-05-15 1994-05-13 Process for the preparation of microballs and microballs thus obtained

Country Status (35)

Country Link
JP (1) JP3139913B2 (en)
KR (1) KR100341261B1 (en)
CN (1) CN1050534C (en)
AT (1) AT406017B (en)
AU (1) AU685094B2 (en)
BE (1) BE1008323A3 (en)
BR (1) BR9401968A (en)
CA (1) CA2123481C (en)
CH (1) CH688572A5 (en)
DE (1) DE4416812C2 (en)
DK (1) DK171454B1 (en)
DZ (1) DZ1779A1 (en)
ES (1) ES2097083B1 (en)
FI (1) FI112915B (en)
FR (1) FR2705232B1 (en)
GB (2) GB9310030D0 (en)
GR (1) GR1002034B (en)
HK (1) HK1002831A1 (en)
HU (1) HU220617B1 (en)
IE (1) IE940392A1 (en)
IN (1) IN182330B (en)
IT (1) IT1269508B (en)
LU (1) LU88482A1 (en)
MA (1) MA23194A1 (en)
NL (1) NL9400795A (en)
NO (1) NO307403B1 (en)
NZ (1) NZ260520A (en)
OA (1) OA09939A (en)
PL (1) PL175780B1 (en)
PT (1) PT101518B (en)
RU (1) RU2125869C1 (en)
SE (1) SE519004C2 (en)
SG (1) SG46631A1 (en)
TN (1) TNSN94046A1 (en)
ZA (1) ZA943316B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU220137B (en) * 1993-01-06 2001-11-28 Kinerton Ltd. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides, process to prepare them and process to prepare microparticles
ATE381349T1 (en) * 1993-01-06 2008-01-15 Ipsen Mfg Ireland Ltd BIODEGRADABLE POLYESTERS FOR PRODUCING IONIC MOLECULAR CONJUGATES WITH BIOACTIVE POLYPEPTIDES
DE19604744A1 (en) 1996-02-09 1997-08-14 Henkel Kgaa Technical di- / triglyceride mixtures
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (en) * 1996-04-29 1997-02-27 Henkel Kgaa Use of branched alcohol ester(s) of olefin-di:carboxylic acid copolymers
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
EP1229940B1 (en) 1999-11-15 2014-05-14 Piramal Healthcare (Canada) Limited Temperature-controlled and ph-dependant self-gelling biopolymeric aqueous solution
KR100558119B1 (en) * 2000-06-16 2006-03-10 가부시키가이샤 닛폰 쇼쿠바이 Crosslinked polymer, method for manufacturing it and use thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (en) * 1987-10-14 1990-01-15 Debiopharm Sa
AU2810189A (en) * 1987-10-30 1989-05-23 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (en) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retarding microparticles made from biodegradable polyesters; Process for their preparation without the use of toxic solvents and pharmaceutical preparations containing these microparticles
DE69123075T2 (en) * 1990-04-12 1997-03-20 Shionogi Seiyaku Kk Coated composition and process for its manufacture
JP3116311B2 (en) * 1990-06-13 2000-12-11 エーザイ株式会社 Manufacturing method of microsphere
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (en) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab PROCEDURE SHOULD FORMULATE MEDICINAL PRODUCTS
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE467815B (en) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm METHOD FOR MAKING REPRODUCABLE PARTICLES OF DEFINED SIZE
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
CA2129514A1 (en) * 1992-03-12 1993-09-16 M. Amin Khan Controlled released acth containing microspheres
SE9200858L (en) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Method for producing delayed release pellets
PT644771E (en) * 1992-06-11 2002-12-31 Alkermes Inc ERITROPOIETIN DRUG DELIVERY SYSTEM
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (en) * 1992-07-16 1997-09-10 田辺製薬株式会社 Method for producing sustained-release microsphere preparation
FR2693905B1 (en) * 1992-07-27 1994-09-02 Rhone Merieux Process for the preparation of microspheres for the sustained release of the hormone LHRH and its analogs, microspheres and formulations obtained.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
ES2097083B1 (en) 1997-12-01
JP3139913B2 (en) 2001-03-05
IT1269508B (en) 1997-04-01
GB2277915B (en) 1997-10-29
FR2705232A1 (en) 1994-11-25
GR1002034B (en) 1995-10-31
PL175780B1 (en) 1999-02-26
DK54994A (en) 1994-11-16
DE4416812C2 (en) 2003-02-06
ZA943316B (en) 1995-01-16
OA09939A (en) 1994-11-15
TNSN94046A1 (en) 1995-04-25
HU220617B1 (en) 2002-03-28
DE4416812A1 (en) 1994-11-17
HK1002831A1 (en) 1998-09-18
NO941810D0 (en) 1994-05-13
NO941810L (en) 1994-11-16
HUT67599A (en) 1995-04-28
IN182330B (en) 1999-03-20
HU9401412D0 (en) 1994-08-29
DZ1779A1 (en) 2002-02-17
KR100341261B1 (en) 2002-09-27
CN1050534C (en) 2000-03-22
AU685094B2 (en) 1998-01-15
GB9409565D0 (en) 1994-07-06
CA2123481C (en) 2005-01-11
BE1008323A3 (en) 1996-04-02
BR9401968A (en) 1994-12-13
GB9310030D0 (en) 1993-06-30
IE940392A1 (en) 1994-11-16
LU88482A1 (en) 1994-12-01
ES2097083A1 (en) 1997-03-16
FI942222A0 (en) 1994-05-13
FI942222A (en) 1994-11-16
PT101518A (en) 1995-03-01
FR2705232B1 (en) 1995-08-25
SE9401557D0 (en) 1994-05-05
RU2125869C1 (en) 1999-02-10
CH688572A5 (en) 1997-11-28
ATA98794A (en) 1999-06-15
FI112915B (en) 2004-02-13
GB2277915A (en) 1994-11-16
AT406017B (en) 2000-01-25
ITMI940931A1 (en) 1995-11-11
DK171454B1 (en) 1996-11-04
ITMI940931A0 (en) 1994-05-11
NZ260520A (en) 1994-12-22
SG46631A1 (en) 1998-02-20
CN1104557A (en) 1995-07-05
MA23194A1 (en) 1994-12-31
NL9400795A (en) 1994-12-01
JPH072652A (en) 1995-01-06
SE9401557L (en) 1994-11-16
NO307403B1 (en) 2000-04-03
PT101518B (en) 2000-12-29
CA2123481A1 (en) 1994-11-16
SE519004C2 (en) 2002-12-17

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