FR2705232B1 - Process for the preparation of dry prepared particles, dry prepared particles thus obtained and pharmaceutical compositions containing such particles. - Google Patents

Process for the preparation of dry prepared particles, dry prepared particles thus obtained and pharmaceutical compositions containing such particles.

Info

Publication number
FR2705232B1
FR2705232B1 FR9405782A FR9405782A FR2705232B1 FR 2705232 B1 FR2705232 B1 FR 2705232B1 FR 9405782 A FR9405782 A FR 9405782A FR 9405782 A FR9405782 A FR 9405782A FR 2705232 B1 FR2705232 B1 FR 2705232B1
Authority
FR
France
Prior art keywords
particles
dry prepared
preparation
pharmaceutical compositions
prepared particles
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
FR9405782A
Other languages
French (fr)
Other versions
FR2705232A1 (en
Inventor
Ruiz Jean-Marc
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ipsen Pharma SAS
Original Assignee
Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS filed Critical Societe de Conseils de Recherches et dApplications Scientifiques SCRAS SAS
Publication of FR2705232A1 publication Critical patent/FR2705232A1/en
Application granted granted Critical
Publication of FR2705232B1 publication Critical patent/FR2705232B1/en
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1605Excipients; Inactive ingredients
    • A61K9/1629Organic macromolecular compounds
    • A61K9/1641Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, poloxamers
    • A61K9/1647Polyesters, e.g. poly(lactide-co-glycolide)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/14Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/16Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
    • A61K9/1682Processes
    • A61K9/1694Processes resulting in granules or microspheres of the matrix type containing more than 5% of excipient
FR9405782A 1993-05-15 1994-05-11 Process for the preparation of dry prepared particles, dry prepared particles thus obtained and pharmaceutical compositions containing such particles. Expired - Fee Related FR2705232B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB939310030A GB9310030D0 (en) 1993-05-15 1993-05-15 Dry processed particles and process for the preparation of the same

Publications (2)

Publication Number Publication Date
FR2705232A1 FR2705232A1 (en) 1994-11-25
FR2705232B1 true FR2705232B1 (en) 1995-08-25

Family

ID=10735537

Family Applications (1)

Application Number Title Priority Date Filing Date
FR9405782A Expired - Fee Related FR2705232B1 (en) 1993-05-15 1994-05-11 Process for the preparation of dry prepared particles, dry prepared particles thus obtained and pharmaceutical compositions containing such particles.

Country Status (35)

Country Link
JP (1) JP3139913B2 (en)
KR (1) KR100341261B1 (en)
CN (1) CN1050534C (en)
AT (1) AT406017B (en)
AU (1) AU685094B2 (en)
BE (1) BE1008323A3 (en)
BR (1) BR9401968A (en)
CA (1) CA2123481C (en)
CH (1) CH688572A5 (en)
DE (1) DE4416812C2 (en)
DK (1) DK171454B1 (en)
DZ (1) DZ1779A1 (en)
ES (1) ES2097083B1 (en)
FI (1) FI112915B (en)
FR (1) FR2705232B1 (en)
GB (2) GB9310030D0 (en)
GR (1) GR1002034B (en)
HK (1) HK1002831A1 (en)
HU (1) HU220617B1 (en)
IE (1) IE940392A1 (en)
IN (1) IN182330B (en)
IT (1) IT1269508B (en)
LU (1) LU88482A1 (en)
MA (1) MA23194A1 (en)
NL (1) NL9400795A (en)
NO (1) NO307403B1 (en)
NZ (1) NZ260520A (en)
OA (1) OA09939A (en)
PL (1) PL175780B1 (en)
PT (1) PT101518B (en)
RU (1) RU2125869C1 (en)
SE (1) SE519004C2 (en)
SG (1) SG46631A1 (en)
TN (1) TNSN94046A1 (en)
ZA (1) ZA943316B (en)

Families Citing this family (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE381349T1 (en) * 1993-01-06 2008-01-15 Ipsen Mfg Ireland Ltd BIODEGRADABLE POLYESTERS FOR PRODUCING IONIC MOLECULAR CONJUGATES WITH BIOACTIVE POLYPEPTIDES
EP0678018B1 (en) * 1993-01-06 2003-04-09 Kinerton Limited Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
DE19604744A1 (en) 1996-02-09 1997-08-14 Henkel Kgaa Technical di- / triglyceride mixtures
IE960308A1 (en) 1996-04-23 1997-11-05 Kinerton Ltd Sustained release ionic conjugate
DE19617137C1 (en) * 1996-04-29 1997-02-27 Henkel Kgaa Use of branched alcohol ester(s) of olefin-di:carboxylic acid copolymers
US5858531A (en) * 1996-10-24 1999-01-12 Bio Syntech Method for preparation of polymer microparticles free of organic solvent traces
US6867181B1 (en) 1997-06-02 2005-03-15 Societe De Conseils De Recherches Et D'applications Scientifiques, S.A.S. Ionic molecular conjugates of biodegradable polyesters and bioactive polypeptides
DK1229940T3 (en) 1999-11-15 2014-08-18 Piramal Healthcare Canada Ltd TEMPERATURE CONTROL AND PH-DEPENDENT SELF-GELING, Aqueous BIOPOLYMER SOLUTION
CA2350728A1 (en) 2000-06-16 2001-12-16 Nippon Shokubai Co., Ltd. Crosslinked polmer, method for manufacturing it and use thereof
GB0705159D0 (en) * 2007-03-19 2007-04-25 Prosonix Ltd Process for making crystals

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3773919A (en) * 1969-10-23 1973-11-20 Du Pont Polylactide-drug mixtures
IE52535B1 (en) * 1981-02-16 1987-12-09 Ici Plc Continuous release pharmaceutical compositions
CH672887A5 (en) * 1987-10-14 1990-01-15 Debiopharm Sa
WO1989003678A1 (en) * 1987-10-30 1989-05-05 Stolle Research & Development Corporation Low residual solvent microspheres and microencapsulation process
DE3916020C2 (en) * 1989-05-17 1994-06-01 Burkhard Dr Wichert Retarding microparticles made from biodegradable polyesters; Process for their preparation without the use of toxic solvents and pharmaceutical preparations containing these microparticles
DE69123075T2 (en) * 1990-04-12 1997-03-20 Shionogi Seiyaku Kk Coated composition and process for its manufacture
JP3116311B2 (en) * 1990-06-13 2000-12-11 エーザイ株式会社 Manufacturing method of microsphere
GB9016885D0 (en) * 1990-08-01 1990-09-12 Scras Sustained release pharmaceutical compositions
GB2246514B (en) * 1990-08-01 1993-12-15 Scras Sustained release pharmaceutical compositions and the preparation of particles for use therein
SE9003296L (en) * 1990-10-16 1992-04-17 Kabi Pharmacia Ab PROCEDURE SHOULD FORMULATE MEDICINAL PRODUCTS
CA2055522A1 (en) * 1990-12-12 1992-06-13 Masako Andoh Microspheres for ophthalmic use
SE467815B (en) * 1991-05-27 1992-09-21 Bengt Hjalmar Aagerup Med Firm METHOD FOR MAKING REPRODUCABLE PARTICLES OF DEFINED SIZE
GB9203689D0 (en) * 1992-02-20 1992-04-08 Euro Celtique Sa Pharmaceutical composition
CA2129514A1 (en) * 1992-03-12 1993-09-16 M. Amin Khan Controlled released acth containing microspheres
SE9200858L (en) * 1992-03-20 1993-09-21 Kabi Pharmacia Ab Method for producing delayed release pellets
CA2136434C (en) * 1992-06-11 2008-12-02 Howard Bernstein Erythropoietin drug delivery system
US5350584A (en) * 1992-06-26 1994-09-27 Merck & Co., Inc. Spheronization process using charged resins
JP2651320B2 (en) * 1992-07-16 1997-09-10 田辺製薬株式会社 Method for producing sustained-release microsphere preparation
FR2693905B1 (en) * 1992-07-27 1994-09-02 Rhone Merieux Process for the preparation of microspheres for the sustained release of the hormone LHRH and its analogs, microspheres and formulations obtained.
GB2273874A (en) * 1992-12-31 1994-07-06 Pertti Olavi Toermaelae Preparation of pharmaceuticals in a polymer matrix

Also Published As

Publication number Publication date
DK171454B1 (en) 1996-11-04
HK1002831A1 (en) 1998-09-18
OA09939A (en) 1994-11-15
MA23194A1 (en) 1994-12-31
TNSN94046A1 (en) 1995-04-25
IE940392A1 (en) 1994-11-16
ES2097083A1 (en) 1997-03-16
IN182330B (en) 1999-03-20
NO941810L (en) 1994-11-16
NZ260520A (en) 1994-12-22
SG46631A1 (en) 1998-02-20
JP3139913B2 (en) 2001-03-05
PT101518B (en) 2000-12-29
GB9409565D0 (en) 1994-07-06
GB2277915B (en) 1997-10-29
NO307403B1 (en) 2000-04-03
IT1269508B (en) 1997-04-01
CA2123481C (en) 2005-01-11
KR100341261B1 (en) 2002-09-27
DZ1779A1 (en) 2002-02-17
GR1002034B (en) 1995-10-31
FI112915B (en) 2004-02-13
AT406017B (en) 2000-01-25
NL9400795A (en) 1994-12-01
HU220617B1 (en) 2002-03-28
HUT67599A (en) 1995-04-28
CN1104557A (en) 1995-07-05
RU2125869C1 (en) 1999-02-10
CH688572A5 (en) 1997-11-28
CA2123481A1 (en) 1994-11-16
SE519004C2 (en) 2002-12-17
SE9401557D0 (en) 1994-05-05
FI942222A0 (en) 1994-05-13
FR2705232A1 (en) 1994-11-25
LU88482A1 (en) 1994-12-01
ITMI940931A1 (en) 1995-11-11
FI942222A (en) 1994-11-16
HU9401412D0 (en) 1994-08-29
GB9310030D0 (en) 1993-06-30
PL175780B1 (en) 1999-02-26
CN1050534C (en) 2000-03-22
ATA98794A (en) 1999-06-15
BE1008323A3 (en) 1996-04-02
AU685094B2 (en) 1998-01-15
ITMI940931A0 (en) 1994-05-11
AU6308494A (en) 1994-11-17
DK54994A (en) 1994-11-16
JPH072652A (en) 1995-01-06
DE4416812A1 (en) 1994-11-17
ES2097083B1 (en) 1997-12-01
BR9401968A (en) 1994-12-13
ZA943316B (en) 1995-01-16
SE9401557L (en) 1994-11-16
GB2277915A (en) 1994-11-16
DE4416812C2 (en) 2003-02-06
PT101518A (en) 1995-03-01
NO941810D0 (en) 1994-05-13

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Legal Events

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TP Transmission of property
TP Transmission of property
CA Change of address
CD Change of name or company name
ST Notification of lapse

Effective date: 20110131