DK168709B1 - Vektorer omfattende et gen, der koder for et primat-GM-CSF-protein, værtsceller transformeret med vektoren, fremgangsmåde til fremstilling af primat-GM-CSF-protein, og cDNA, der svarer til det CFS-kodende gen - Google Patents

Vektorer omfattende et gen, der koder for et primat-GM-CSF-protein, værtsceller transformeret med vektoren, fremgangsmåde til fremstilling af primat-GM-CSF-protein, og cDNA, der svarer til det CFS-kodende gen Download PDF

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Publication number
DK168709B1
DK168709B1 DK102886A DK102886A DK168709B1 DK 168709 B1 DK168709 B1 DK 168709B1 DK 102886 A DK102886 A DK 102886A DK 102886 A DK102886 A DK 102886A DK 168709 B1 DK168709 B1 DK 168709B1
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csf
protein
cdna
cell
cells
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DK102886A
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Danish (da)
English (en)
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DK102886D0 (da
DK102886A (da
Inventor
Steven C Clark
Gordon G Wong
Randal J Kaufman
Elizabeth A Wang
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Sandoz Ag
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/70Vectors or expression systems specially adapted for E. coli
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2840/00Vectors comprising a special translation-regulating system
    • C12N2840/44Vectors comprising a special translation-regulating system being a specific part of the splice mechanism, e.g. donor, acceptor
DK102886A 1984-07-06 1986-03-06 Vektorer omfattende et gen, der koder for et primat-GM-CSF-protein, værtsceller transformeret med vektoren, fremgangsmåde til fremstilling af primat-GM-CSF-protein, og cDNA, der svarer til det CFS-kodende gen DK168709B1 (da)

Applications Claiming Priority (8)

Application Number Priority Date Filing Date Title
US62834284A 1984-07-06 1984-07-06
US62834284 1984-07-06
US65274284A 1984-09-19 1984-09-19
US65244784A 1984-09-19 1984-09-19
US65244784 1984-09-19
US65274284 1984-09-19
EP8500326 1985-07-04
PCT/EP1985/000326 WO1986000639A1 (en) 1984-07-06 1985-07-04 Lymphokine production and purification

Publications (3)

Publication Number Publication Date
DK102886D0 DK102886D0 (da) 1986-03-06
DK102886A DK102886A (da) 1986-03-06
DK168709B1 true DK168709B1 (da) 1994-05-24

Family

ID=27417446

Family Applications (2)

Application Number Title Priority Date Filing Date
DK102886A DK168709B1 (da) 1984-07-06 1986-03-06 Vektorer omfattende et gen, der koder for et primat-GM-CSF-protein, værtsceller transformeret med vektoren, fremgangsmåde til fremstilling af primat-GM-CSF-protein, og cDNA, der svarer til det CFS-kodende gen
DK199300594A DK172679B1 (da) 1984-07-06 1993-05-21 CSF-protein

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK199300594A DK172679B1 (da) 1984-07-06 1993-05-21 CSF-protein

Country Status (28)

Country Link
EP (2) EP0337359B1 (xx)
JP (4) JP2540509B2 (xx)
KR (1) KR910001809B1 (xx)
AT (2) ATE67244T1 (xx)
AU (3) AU599572B2 (xx)
CA (2) CA1341618C (xx)
CY (1) CY1629A (xx)
DE (3) DE3588199T2 (xx)
DK (2) DK168709B1 (xx)
ES (1) ES8701226A1 (xx)
FI (1) FI108796B (xx)
GR (1) GR851643B (xx)
HK (2) HK111594A (xx)
HU (1) HU208711B (xx)
IE (2) IE930961L (xx)
IL (2) IL75725A (xx)
LU (1) LU88337I2 (xx)
MY (1) MY102902A (xx)
NL (1) NL930089I2 (xx)
NO (4) NO179455C (xx)
NZ (2) NZ228031A (xx)
PL (1) PL153139B1 (xx)
PT (1) PT80776B (xx)
SA (1) SA94150015A (xx)
SG (1) SG108991G (xx)
SK (1) SK280265B6 (xx)
UA (1) UA39161C2 (xx)
WO (1) WO1986000639A1 (xx)

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Also Published As

Publication number Publication date
DE188479T1 (de) 1987-05-21
NL930089I1 (nl) 1993-10-01
DK59493A (da) 1993-05-21
SK505985A3 (en) 1999-10-08
ATE172494T1 (de) 1998-11-15
FI860308A (fi) 1986-01-22
WO1986000639A1 (en) 1986-01-30
IE851695L (en) 1986-01-06
LU88337I2 (fr) 1994-05-04
PT80776B (pt) 1987-09-30
AU644359B2 (en) 1993-12-09
IL75725A0 (en) 1985-11-29
JPH06319557A (ja) 1994-11-22
AU628069B2 (en) 1992-09-10
DK172679B1 (da) 1999-05-17
NZ212645A (en) 1990-02-26
JP2540509B2 (ja) 1996-10-02
AU4545685A (en) 1986-02-10
NO943300L (no) 1986-03-13
NO943300D0 (no) 1994-09-07
AU4009089A (en) 1989-12-07
JP2594768B2 (ja) 1997-03-26
NO961452D0 (no) 1996-04-12
HK1011709A1 (en) 1999-07-16
IE60819B1 (en) 1994-08-10
PT80776A (en) 1985-08-01
NL930089I2 (nl) 1994-07-01
NZ228031A (en) 1991-12-23
PL254400A1 (en) 1986-06-17
PL153139B1 (en) 1991-03-29
HUT38675A (en) 1986-06-30
IL94754A0 (en) 1991-04-15
FI860308A0 (fi) 1986-01-22
ES8701226A1 (es) 1986-11-16
DK59493D0 (da) 1993-05-21
HK111594A (en) 1994-10-21
JPH06199897A (ja) 1994-07-19
NO179455C (no) 1996-10-09
ES544868A0 (es) 1986-11-16
IL75725A (en) 1993-02-21
DE3588199T2 (de) 1999-04-08
KR860700264A (ko) 1986-08-01
DE3584089D1 (de) 1991-10-17
EP0188479B1 (en) 1991-09-11
AU599572B2 (en) 1990-07-26
NO314941B1 (no) 2003-06-16
MY102902A (en) 1993-03-31
SA94150015B1 (ar) 2004-09-04
NO860775L (no) 1986-03-13
NO179455B (no) 1996-07-01
IE930961L (en) 1986-01-06
NO307348B1 (no) 2000-03-20
NO961452L (no) 1996-04-12
NO1996016I1 (no) 1996-12-18
KR910001809B1 (ko) 1991-03-26
EP0337359B1 (en) 1998-10-21
DK102886D0 (da) 1986-03-06
UA39161C2 (uk) 2001-06-15
DK102886A (da) 1986-03-06
EP0188479A1 (en) 1986-07-30
SG108991G (en) 1992-03-20
CY1629A (en) 1992-07-10
AU5497690A (en) 1990-09-13
JPH07163351A (ja) 1995-06-27
SK280265B6 (sk) 1999-10-08
SA94150015A (ar) 2005-12-03
DE3588199D1 (de) 1998-11-26
GR851643B (xx) 1985-11-26
ATE67244T1 (de) 1991-09-15
JP2594743B2 (ja) 1997-03-26
CA1341618C (en) 2011-07-19
JP2594744B2 (ja) 1997-03-26
HU208711B (en) 1993-12-28
CA1340852C (en) 1999-12-14
JPS61502682A (ja) 1986-11-20
EP0337359A3 (en) 1990-02-07
EP0337359A2 (en) 1989-10-18
FI108796B (fi) 2002-03-28

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B1 Patent granted (law 1993)
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Free format text: CA 1994 00007, 940621

CTFF Application for supplementary protection certificate (spc) filed

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CTFG Supplementary protection certificate (spc) issued

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