DK1474067T4 - En-dosis vaccination med I Mycoplasma Hyopneumoniae/I - Google Patents

En-dosis vaccination med I Mycoplasma Hyopneumoniae/I Download PDF

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Publication number
DK1474067T4
DK1474067T4 DK02735755.7T DK02735755T DK1474067T4 DK 1474067 T4 DK1474067 T4 DK 1474067T4 DK 02735755 T DK02735755 T DK 02735755T DK 1474067 T4 DK1474067 T4 DK 1474067T4
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hyo
vaccine
pigs
mycoplasma hyopneumoniae
use according
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DK02735755.7T
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DK1474067T3 (da
Inventor
Robin Lee Keich
Lisa Grace Sabbadini
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Zoetis Services Llc
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K39/02Bacterial antigens
    • A61K39/0241Mollicutes, e.g. Mycoplasma, Erysipelothrix
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/52Bacterial cells; Fungal cells; Protozoal cells
    • A61K2039/521Bacterial cells; Fungal cells; Protozoal cells inactivated (killed)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/51Medicinal preparations containing antigens or antibodies comprising whole cells, viruses or DNA/RNA
    • A61K2039/53DNA (RNA) vaccination
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/55Medicinal preparations containing antigens or antibodies characterised by the host/recipient, e.g. newborn with maternal antibodies
    • A61K2039/552Veterinary vaccine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/555Medicinal preparations containing antigens or antibodies characterised by a specific combination antigen/adjuvant
    • A61K2039/55511Organic adjuvants
    • A61K2039/55555Liposomes; Vesicles, e.g. nanoparticles; Spheres, e.g. nanospheres; Polymers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/8215Microorganisms
    • Y10S435/822Microorganisms using bacteria or actinomycetales
    • Y10S435/87Mycoplasma

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  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Claims (9)

1. Anvendelse af Mycoplasma hyopneumoniae bakterin til fremstilling af en vaccine til behandling eller forebyggelse, hos grise, der er seronegative for Mycoplasma hyopneumoniae, af en sygdom eller lidelse forårsaget af infektion med Mycoplasma hyopneumoniae, til administration til grisene ved fra 3 til 10 dage gamle af en effektiv indgivelsesmængde af en enkelt dosis af Mycoplasma hyopneumoniae vaccinen.
2. Anvendelse ifølge krav 1, hvor den enkelte dosis af M. hyopneumoniae vaccinen indeholder fra 1x106 til 5x1010 farveændrende enheder (CCU) pr. dosis.
3. Anvendelse ifølge krav 1, hvor mængden af nævnte administrerede vaccine er fra 0,5 til 3,0 ml.
4. Anvendelse ifølge krav 1, hvor Mycoplasma hyopneumoniae bakterin indeholder stamme P-5722-3.
5. Anvendelse ifølge krav 1, hvor Mycoplasma hyopneumoniae vaccinen yderligere omfatter et viralt eller bakterielt antigen andet end Mycoplasma hyopneumoniae.
6. Anvendelse ifølge krav 5, hvor nævnte virale eller bakterielle antigener vælges fra svineinfluenza virus (SIV), porcin-reproduktions- og respiratorisk sygdomsvirus (PRRS eller mystisk svinesygdom), post-smådyr diarrhea (PWD) og porcin proliferativ enteritis (PPE).
7. Anvendelse ifølge krav 1, hvor nævnte Mycoplasma hyopneumoniae fremstilling er til intramuskulær administration.
8. Anvendelse ifølge krav 1, hvor nævnte grise beskyttes op til 25 uger efter vaccination.
9. Anvendelse ifølge krav 1, hvor Mycoplasma hyopneumoniae vaccinen yderligere omfatter et adjuvans.
DK02735755.7T 2001-07-02 2002-06-07 En-dosis vaccination med I Mycoplasma Hyopneumoniae/I DK1474067T4 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US30263601P 2001-07-02 2001-07-02
PCT/IB2002/002121 WO2003003941A2 (en) 2001-07-02 2002-06-07 One dose vaccination with mycoplasma hyopneumoniae

Publications (2)

Publication Number Publication Date
DK1474067T3 DK1474067T3 (da) 2008-12-08
DK1474067T4 true DK1474067T4 (da) 2017-10-16

Family

ID=23168589

Family Applications (3)

Application Number Title Priority Date Filing Date
DK02735755.7T DK1474067T4 (da) 2001-07-02 2002-06-07 En-dosis vaccination med I Mycoplasma Hyopneumoniae/I
DK08167761.9T DK2027873T3 (da) 2001-07-02 2002-06-07 Enkeltdosisvaccination med mycoplasma hyopneumoniae
DK14182639.6T DK2842569T3 (da) 2001-07-02 2002-06-07 Vaccination i en dosis med Mycoplasma hyopneumoniae

Family Applications After (2)

Application Number Title Priority Date Filing Date
DK08167761.9T DK2027873T3 (da) 2001-07-02 2002-06-07 Enkeltdosisvaccination med mycoplasma hyopneumoniae
DK14182639.6T DK2842569T3 (da) 2001-07-02 2002-06-07 Vaccination i en dosis med Mycoplasma hyopneumoniae

Country Status (42)

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US (3) US6846477B2 (da)
EP (3) EP2842569B1 (da)
JP (1) JP2005515162A (da)
KR (1) KR20040030785A (da)
CN (3) CN101524532B (da)
AP (1) AP2003002937A0 (da)
AR (1) AR034678A1 (da)
AT (1) ATE412426T2 (da)
AU (1) AU2002309109B2 (da)
BG (1) BG66481B1 (da)
BR (1) BR0210804A (da)
CA (1) CA2451626C (da)
CY (1) CY1108749T1 (da)
CZ (1) CZ305781B6 (da)
DE (1) DE60229666D1 (da)
DK (3) DK1474067T4 (da)
DO (1) DOP2002000431A (da)
EA (1) EA009901B1 (da)
ES (3) ES2550458T3 (da)
GT (1) GT200200138A (da)
HK (4) HK1068250A1 (da)
HR (1) HRP20031079A2 (da)
HU (1) HU230246B1 (da)
IL (1) IL159349A0 (da)
IS (1) IS7076A (da)
MA (1) MA27047A1 (da)
MX (1) MXPA03011599A (da)
NO (1) NO342654B1 (da)
NZ (1) NZ530106A (da)
OA (1) OA12638A (da)
PA (1) PA8549701A1 (da)
PE (1) PE20030285A1 (da)
PL (1) PL209773B1 (da)
PT (3) PT2842569T (da)
SK (1) SK288010B6 (da)
TN (1) TNSN03155A1 (da)
TW (1) TWI329514B (da)
UA (1) UA78707C2 (da)
UY (1) UY27366A1 (da)
WO (1) WO2003003941A2 (da)
YU (1) YU102203A (da)
ZA (1) ZA200309698B (da)

Families Citing this family (52)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
MY129765A (en) * 2000-12-19 2007-04-30 Wyeth Corp Improved mycoplasma hyopneumoniae bacterin vaccine
WO2006056841A1 (en) * 2004-11-24 2006-06-01 Pharmacia & Upjohn Company Llc Multiple-strain mycoplasma hyopneumoniae vaccines
US7833707B2 (en) 2004-12-30 2010-11-16 Boehringer Ingelheim Vetmedica, Inc. Methods of overexpression and recovery of porcine circovirus type 2 ORF2
UA95602C2 (ru) 2004-12-30 2011-08-25 Берингер Ингельхейм Ветмедика, Инк. Иммуногенная композиция цвс2 и способы приготовления такой композиции
US7700285B1 (en) 2005-12-29 2010-04-20 Boehringer Ingelheim Vetmedica, Inc. PCV2 immunogenic compositions and methods of producing such compositions
US8834891B2 (en) 2005-03-14 2014-09-16 Boehringer Ingelheim Vetmedica, Inc. Immunogenic compositions comprising Lawsonia intracellularis
DK2371383T3 (da) 2005-12-29 2015-11-30 Boehringer Ingelheim Vetmed Anvendelse af en PCV2-immunogen sammensætning til mindskning af kliniske symptomer i grise
HUE054868T2 (hu) 2005-12-29 2021-10-28 Boehringer Ingelheim Animal Health Usa Inc Multivalens PVC2 immunogén készítmények és eljárások ezek elõállítására
BRPI0708522A2 (pt) * 2006-03-03 2011-05-31 Merial Ltd vacina de mycoplasma hyopneumoniae
WO2008064299A2 (en) * 2006-11-22 2008-05-29 Boehringer Ingelheim Vetmedica, Inc. Methods of reducing porcine circovirus-associated disease outbreaks
US20100129397A1 (en) * 2006-12-11 2010-05-27 Boehringer Ingelheim Vetmedica, Inc. Effective method of treatment of porcine circovirus and lawsonia intracellularis infections
RU2520087C2 (ru) 2006-12-15 2014-06-20 Бёрингер Ингельхайм Ветмедика, Инк. Лечение свиней с помощью антигена pcv2
EP1941903A1 (en) 2007-01-03 2008-07-09 Boehringer Ingelheim Vetmedica Gmbh Prophylaxis and treatment of PRDC
EP1958644A1 (en) 2007-02-13 2008-08-20 Boehringer Ingelheim Vetmedica Gmbh Prevention and treatment of sub-clinical pcvd
US7829274B2 (en) 2007-09-04 2010-11-09 Boehringer Ingelheim Vetmedica, Inc. Reduction of concomitant infections in pigs by the use of PCV2 antigen
MX2010005014A (es) * 2007-11-06 2010-06-30 Wyeth Llc Vacuna viva avirulenta de mycoplasma hyopneumoniae con adyuvante.
EP2231182A4 (en) * 2007-12-31 2012-08-22 Boehringer Ingelheim Vetmed PCV2-ORF2-VIRUSELY PARTICLES WITH FREMDAMINO-ACID INSERTION
CN101236206B (zh) * 2008-01-17 2014-10-15 中国兽医药品监察所 一种猪肺炎支原体重组抗原elisa检测试剂盒
US20090317423A1 (en) 2008-01-23 2009-12-24 Boehringer Ingelheim Vetmedica, Inc. Pcv2 mycoplasma hyopneumoniae immunogenic compositions and methods of producing such compositions
US8444989B1 (en) * 2008-04-18 2013-05-21 Boehringer Ingelheim Vetmedica Gmbh One dose vaccination against mycoplasma infections of pigs
DK2310046T3 (da) 2008-06-27 2016-04-25 Zoetis Services Llc Hidtil ukendte adjuvanssammensætninger
CN102448488B (zh) 2009-06-04 2014-10-15 独立行政法人产业技术综合研究所 支原体感染症用疫苗
TWI627281B (zh) 2009-09-02 2018-06-21 百靈佳殷格翰家畜藥品公司 降低pcv-2組合物殺病毒活性之方法及具有改良免疫原性之pcv-2組合物
EP3187585A1 (en) 2010-03-25 2017-07-05 Oregon Health&Science University Cmv glycoproteins and recombinant vectors
WO2011141443A1 (en) 2010-05-11 2011-11-17 Intervet International B.V. Vaccine against mycoplasma hyopneumoniae, suitable for administration in the presence of maternally derived antibodies
CA2804709A1 (en) * 2010-07-26 2012-02-02 Qu Biologics Inc. Immunogenic anti-inflammatory compositions
US8546149B2 (en) 2010-08-27 2013-10-01 Intervet Inc. Potency test for vaccine formulations
BR112013004594B1 (pt) * 2010-08-27 2020-07-28 Intervet International B. V. método para a determinação de um conteúdo de antígeno
PL2691530T3 (pl) 2011-06-10 2019-02-28 Oregon Health & Science University Glikoproteiny i rekombinowane wektory CMV
BR112014022067B1 (pt) 2012-03-07 2022-05-31 Ceva Sante Animale Composição compreendendo antígeno e lipopolissacarídeo
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs
US9120859B2 (en) 2012-04-04 2015-09-01 Zoetis Services Llc Mycoplasma hyopneumoniae vaccine
UA114503C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv та mycoplasma hyopneumoniae
EP2938356B1 (en) * 2012-12-28 2020-05-13 Boehringer Ingelheim Vetmedica GmbH Immunogenic composition comprising mycoplasma antigens
CN104968365B (zh) 2012-12-28 2018-04-03 勃林格殷格翰动物保健有限公司 支原体疫苗的制备方法
BR112015018444A2 (pt) * 2013-02-05 2018-05-08 Agricultural Technology Research Institute composição para prevenir infecção de mycoplasma spp., e vetor de expressão
CN104338125A (zh) * 2013-07-29 2015-02-11 普莱柯生物工程股份有限公司 一种猪肺炎支原体抗原在预防和治疗猪呼吸道疾病综合征方面的应用
CA3005608C (en) 2013-09-19 2020-06-30 Zoetis Services Llc Water-in-oil emulsions comprising immunostimulatory oligonucleotides
EA035265B1 (ru) 2013-10-02 2020-05-21 Бёрингер Ингельхайм Энимал Хелс Ю-Эс-Эй Инк. Вариант белка opc2 pcv2 и содержащие его вирусоподобные частицы
KR101842081B1 (ko) 2013-11-21 2018-03-26 애그리컬쳐럴 테크놀로지 리서치 인스티튜트 마이코플라즈마 에스피피 감염을 예방하기 위한 조성물
CN105012948B (zh) * 2014-04-18 2019-07-30 普莱柯生物工程股份有限公司 一种疫苗组合物及其应用
CN104248753B (zh) * 2014-05-15 2017-07-28 普莱柯生物工程股份有限公司 一种疫苗组合物及其应用
BR102014014727B1 (pt) * 2014-06-16 2018-04-03 Ouro Fino Saúde Animal Ltda COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, GENE SINTÉTICO CODIFICANTE DO COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae, COMPOSIÇÃO ANTIGÊNICA, PROCESSO DE OBTENÇÃO DE UM COMPLEXO DE POLIPROTEÍNAS IMUNOGÊNICAS DE M. hyopneumoniae
US9814769B2 (en) 2014-09-30 2017-11-14 Qatar University Vaccines against pathogenic Escherichia coli and methods of using the same
KR20170097116A (ko) 2015-01-16 2017-08-25 조에티스 서비시즈 엘엘씨 구제역 백신
KR20160099223A (ko) * 2015-02-12 2016-08-22 강원대학교산학협력단 마이코플라스마 하이오뉴모니애 박테린 백신 및 이의 제조방법
US10519199B2 (en) * 2016-08-12 2019-12-31 Innovac Vaccine composition comprising recombinant protein for preventing swine Mycoplasma infection
RU2668799C1 (ru) * 2017-09-08 2018-10-02 Эгрикалчурал Текнолоджи Рисерч Инститьют Субъединичная вакцина против mycoplasma spp.
CN108101969A (zh) * 2017-11-13 2018-06-01 南京大爻网络科技有限公司 一种与猪支原体肺炎相关的抗原及其应用
RU2695679C1 (ru) * 2018-09-11 2019-07-25 Эгрикалчурал Текнолоджи Рисерч Инститьют Субъединичная вакцина против mycoplasma spp.
RU2759427C2 (ru) * 2019-07-08 2021-11-12 Эгрикалчурал Текнолоджи Рисерч Инститьют Субъединичная вакцина против mycoplasma spp
CN117305192A (zh) * 2023-12-01 2023-12-29 北京瑞阳瑞泰生物科技有限公司 一种猪肺炎支原体rt02株、疫苗组合物及其应用

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0283840A3 (en) * 1987-03-26 1989-08-09 Ml Technology Ventures, L.P. Mycoplasma hyopneumoniae antigen and uses therefor
US5252328A (en) * 1987-03-26 1993-10-12 Martin Marietta Energy Systems, Inc. Mycoplasma hyopneumoniae antigen and uses therefor
ES2058237T3 (es) 1987-09-18 1994-11-01 Akzo Nv Metodo para la preparacion de una vacuna para combatir la infeccion mycoplasmica en aves de corral.
CA2078131A1 (en) 1990-04-02 1991-10-03 Jerry M. Kuner Polypeptides useful in diagnosis of and treatment against mycoplasma infections in animals
US6113916A (en) * 1990-05-29 2000-09-05 American Cyanamid Company Method of enhancing cell mediated immune responses
EP0597852B2 (en) 1990-05-29 2005-08-10 Wyeth Holdings Corporation Swine pneumonia vaccine and method for the preparation thereof
US5565205A (en) 1990-08-16 1996-10-15 Solvay Animal Health, Inc. Inactivated Mycoplasma hypopneumoniae bacterin and method of use thereof
EP0475185A1 (en) 1990-08-27 1992-03-18 Nippon Flour Mills Co., Ltd. DNA's encoding surface antigen of mycoplasma hyopneumoniae, DNA fragments for primer, recombinant antigenic peptides and diagnostic method of mycoplasmal pneumoniae of swine using same
US5338543A (en) * 1992-02-27 1994-08-16 Ambico, Inc. Thimerosal inactivated mycoplasma hyopneumoniae vaccine
ES2225825T3 (es) * 1992-09-28 2005-03-16 Wyeth Holdings Corporation Procedimiento de mejora de las respuestas inmunitarias mediadas por celulas.
US5530874A (en) 1993-02-02 1996-06-25 3Com Corporation Network adapter with an indication signal mask and an interrupt signal mask
WO1995009870A1 (en) 1993-10-07 1995-04-13 Iowa State University Research Foundation, Inc. Characterization of mycoplasma hyopneumoniae adhesins
DE69535520T2 (de) 1994-05-10 2008-02-07 Wyeth Abgeänderter, verbesserter BRSV Lebend- Impfstoff
US5788962A (en) 1995-01-17 1998-08-04 The Curators Of The University Of Missouri DNA sequences coding for mycoplasma hyopneumoniae surface antigens, corresponding proteins and use in vaccines and diagnostic procedures
AUPN178995A0 (en) * 1995-03-16 1995-04-13 University Of Melbourne, The Antigen composition
ATE272409T1 (de) 1996-09-30 2004-08-15 Univ Arkansas Verfahren zur erzeugung aktiver immunität durch vakzinkonjugate
EP0846468B1 (en) 1996-12-05 2004-06-09 Akzo Nobel N.V. Non-virulent mycoplasma synoviae and vaccine thereof
KR20010032493A (ko) 1997-11-26 2001-04-25 아이오와 스테이트 유니버시티 리서치 파운데이션, 인코퍼레이티드 재조합 미코플라스마 히오뉴모니아(Mycoplasmahyopneumoniae) 백신
AU6128900A (en) * 1999-09-29 2001-04-05 Pfizer Products Inc. Nucleic acids and proteins of the mycoplasma hyopneumoniae mph3 gene and uses thereof
US6585981B1 (en) * 2000-07-27 2003-07-01 Regents Of The University Of Minnesota Temperature-sensitive live vaccine for Mycoplasma hyopneumoniae
UA114504C2 (uk) 2012-04-04 2017-06-26 Зоетіс Сервісіз Ллс Комбінована вакцина pcv, mycoplasma hyopneumoniae та prrs

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GT200200138A (es) 2003-05-15
CN101524532A (zh) 2009-09-09
SK15792003A3 (sk) 2005-09-08
PA8549701A1 (es) 2003-01-24
ATE412426T2 (de) 2008-11-15
EP2027873B8 (en) 2015-11-11
USRE44399E1 (en) 2013-07-30
AU2002309109B2 (en) 2007-12-13
UY27366A1 (es) 2003-04-30
DE60229666D1 (de) 2008-12-11
BG108546A (bg) 2005-02-28
EP1474067A2 (en) 2004-11-10
MXPA03011599A (es) 2005-03-07
PT1474067E (pt) 2008-11-14
CN1551781A (zh) 2004-12-01
PE20030285A1 (es) 2003-03-27
HK1068250A1 (en) 2005-04-29
BR0210804A (pt) 2005-05-03
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US6846477B2 (en) 2005-01-25
IS7076A (is) 2003-12-15
US20030109473A1 (en) 2003-06-12
PT2842569T (pt) 2019-06-17
CN102872456B (zh) 2016-01-20
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EA200301323A1 (ru) 2005-06-30
US20050013823A1 (en) 2005-01-20
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HU230246B1 (hu) 2015-11-30
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DK2027873T3 (da) 2015-11-09
ZA200309698B (en) 2014-04-30
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