DK141935B - Analogifremgangsmåde til fremstilling af aryloxyaminobutanoler eller deres stereoisomere eller syreadditionssalte deraf. - Google Patents

Analogifremgangsmåde til fremstilling af aryloxyaminobutanoler eller deres stereoisomere eller syreadditionssalte deraf. Download PDF

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Publication number
DK141935B
DK141935B DK60875AA DK60875A DK141935B DK 141935 B DK141935 B DK 141935B DK 60875A A DK60875A A DK 60875AA DK 60875 A DK60875 A DK 60875A DK 141935 B DK141935 B DK 141935B
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DK
Denmark
Prior art keywords
compounds
general formula
hydroxy
group
carbon atoms
Prior art date
Application number
DK60875AA
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Danish (da)
English (en)
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DK60875A (US06649357-20031118-C00005.png
DK141935C (US06649357-20031118-C00005.png
Inventor
Kalman Harsanyi
Dezsoe Korbonits
Jozsef Szegi
Erzsebet Molnar
Original Assignee
Chinoin Gyogyszer Es Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Chinoin Gyogyszer Es Vegyeszet filed Critical Chinoin Gyogyszer Es Vegyeszet
Publication of DK60875A publication Critical patent/DK60875A/da
Publication of DK141935B publication Critical patent/DK141935B/da
Application granted granted Critical
Publication of DK141935C publication Critical patent/DK141935C/da

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/52Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups or amino groups bound to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B2200/00Indexing scheme relating to specific properties of organic compounds
    • C07B2200/07Optical isomers
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00Systems containing only non-condensed rings
    • C07C2601/12Systems containing only non-condensed rings with a six-membered ring
    • C07C2601/14The ring being saturated

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK60875AA 1974-02-20 1975-02-19 Analogifremgangsmåde til fremstilling af aryloxyaminobutanoler eller deres stereoisomere eller syreadditionssalte deraf. DK141935B (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HUCI1449A HU169464B (US06649357-20031118-C00005.png) 1974-02-20 1974-02-20
HUCI001449 1974-02-20

Publications (3)

Publication Number Publication Date
DK60875A DK60875A (US06649357-20031118-C00005.png) 1975-10-20
DK141935B true DK141935B (da) 1980-07-21
DK141935C DK141935C (US06649357-20031118-C00005.png) 1980-12-08

Family

ID=10994508

Family Applications (1)

Application Number Title Priority Date Filing Date
DK60875AA DK141935B (da) 1974-02-20 1975-02-19 Analogifremgangsmåde til fremstilling af aryloxyaminobutanoler eller deres stereoisomere eller syreadditionssalte deraf.

Country Status (22)

Country Link
JP (1) JPS5929063B2 (US06649357-20031118-C00005.png)
AT (1) AT339281B (US06649357-20031118-C00005.png)
BE (1) BE825745A (US06649357-20031118-C00005.png)
BG (2) BG26366A3 (US06649357-20031118-C00005.png)
CA (1) CA1074338A (US06649357-20031118-C00005.png)
CH (1) CH619684A5 (US06649357-20031118-C00005.png)
CS (1) CS199578B2 (US06649357-20031118-C00005.png)
DD (1) DD119414A5 (US06649357-20031118-C00005.png)
DE (1) DE2506355C2 (US06649357-20031118-C00005.png)
DK (1) DK141935B (US06649357-20031118-C00005.png)
ES (2) ES434784A1 (US06649357-20031118-C00005.png)
FI (1) FI61304C (US06649357-20031118-C00005.png)
FR (1) FR2261001B1 (US06649357-20031118-C00005.png)
GB (1) GB1457086A (US06649357-20031118-C00005.png)
HU (1) HU169464B (US06649357-20031118-C00005.png)
IL (1) IL46634A (US06649357-20031118-C00005.png)
NL (1) NL182698C (US06649357-20031118-C00005.png)
NO (1) NO141754C (US06649357-20031118-C00005.png)
PL (2) PL99025B1 (US06649357-20031118-C00005.png)
SE (1) SE433935B (US06649357-20031118-C00005.png)
SU (1) SU1025327A3 (US06649357-20031118-C00005.png)
YU (2) YU36916B (US06649357-20031118-C00005.png)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154288B (da) * 1974-10-25 1988-10-31 Robins Co Inc A H Analogifremgangsmaade til fremstilling af 1-aryloxy-4-amino-2-butanoler

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0097000B1 (en) * 1982-06-10 1987-09-09 Beecham Wuelfing GmbH & Co KG Amine derivatives

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE368197B (US06649357-20031118-C00005.png) * 1968-11-18 1974-06-24 Pfizer
GB1245148A (en) * 1968-11-18 1971-09-08 Pfizer Ltd Propanolamine derivatives
SE384853B (sv) * 1972-04-04 1976-05-24 Haessle Ab Forfarande for framstellning av nya aminer
AT305245B (de) * 1969-09-24 1973-02-12 Ici Ltd Verfahren zur Herstellung von neuen substituierten 1-Phenoxy-2-hydroxy-3-alkylaminopropanen und von deren Säureadditionssalzen

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK154288B (da) * 1974-10-25 1988-10-31 Robins Co Inc A H Analogifremgangsmaade til fremstilling af 1-aryloxy-4-amino-2-butanoler

Also Published As

Publication number Publication date
NL182698C (nl) 1988-05-02
FR2261001B1 (US06649357-20031118-C00005.png) 1978-07-21
CS199578B2 (en) 1980-07-31
HU169464B (US06649357-20031118-C00005.png) 1976-11-28
FI61304C (fi) 1982-07-12
BG26366A3 (bg) 1979-03-15
SE7501801L (US06649357-20031118-C00005.png) 1975-08-21
DE2506355A1 (de) 1975-08-21
JPS50117728A (US06649357-20031118-C00005.png) 1975-09-16
DK60875A (US06649357-20031118-C00005.png) 1975-10-20
DD119414A5 (US06649357-20031118-C00005.png) 1976-04-20
BE825745A (fr) 1975-06-16
JPS5929063B2 (ja) 1984-07-18
IL46634A0 (en) 1975-04-25
ES434784A1 (es) 1977-03-16
FI750443A (US06649357-20031118-C00005.png) 1975-08-21
NL7501951A (nl) 1975-08-22
ATA114075A (de) 1977-02-15
SU1025327A3 (ru) 1983-06-23
YU37116B (en) 1984-08-31
SE433935B (sv) 1984-06-25
YU36916B (en) 1984-08-31
FI61304B (fi) 1982-03-31
PL99025B1 (pl) 1978-06-30
DK141935C (US06649357-20031118-C00005.png) 1980-12-08
AT339281B (de) 1977-10-10
YU167681A (en) 1983-04-27
BG26367A4 (bg) 1979-03-15
GB1457086A (en) 1976-12-01
NO750566L (US06649357-20031118-C00005.png) 1975-08-21
YU37375A (en) 1982-06-18
PL99023B1 (pl) 1978-06-30
DE2506355C2 (de) 1983-10-06
CA1074338A (en) 1980-03-25
ES453326A1 (es) 1977-11-16
CH619684A5 (en) 1980-10-15
NO141754B (no) 1980-01-28
FR2261001A1 (US06649357-20031118-C00005.png) 1975-09-12
NO141754C (no) 1980-05-07
IL46634A (en) 1979-01-31

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