SE384853B - Forfarande for framstellning av nya aminer - Google Patents

Forfarande for framstellning av nya aminer

Info

Publication number
SE384853B
SE384853B SE7204321A SE432172A SE384853B SE 384853 B SE384853 B SE 384853B SE 7204321 A SE7204321 A SE 7204321A SE 432172 A SE432172 A SE 432172A SE 384853 B SE384853 B SE 384853B
Authority
SE
Sweden
Prior art keywords
procedure
preparation
new amines
amines
new
Prior art date
Application number
SE7204321A
Other languages
English (en)
Inventor
P B Berntsson
A E Brendstrom
E I Carlsson
S A I Carlsson
L Ek
B R Samuelsson
S E Sjostrand
G C Strandlund
B A H Ablad
Original Assignee
Haessle Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Haessle Ab filed Critical Haessle Ab
Priority to SE7204321A priority Critical patent/SE384853B/sv
Priority to AR250907A priority patent/AR204982A1/es
Priority to ZA732119A priority patent/ZA732119B/xx
Priority to BE129334A priority patent/BE797414A/xx
Priority to FR7312015A priority patent/FR2179069B1/fr
Priority to ES413316A priority patent/ES413316A1/es
Priority to IE520/73A priority patent/IE38302B1/xx
Priority to SU1907907A priority patent/SU533336A3/ru
Priority to NL7304606A priority patent/NL7304606A/xx
Priority to CA167,812A priority patent/CA1017755A/en
Priority to FI1026/73A priority patent/FI63741C/fi
Priority to GB1584673A priority patent/GB1421824A/en
Priority to NO1377/73A priority patent/NO139167C/no
Priority to CH481673A priority patent/CH587222A5/xx
Priority to CH237976A priority patent/CH587224A5/xx
Priority to US05/347,625 priority patent/US3996382A/en
Priority to AT293873A priority patent/AT321276B/de
Priority to AT242774A priority patent/AT321893B/de
Priority to BR732430A priority patent/BR7302430D0/pt
Priority to JP48037950A priority patent/JPS5924971B2/ja
Priority to DE2316727A priority patent/DE2316727C3/de
Priority to CH238076A priority patent/CH587225A5/xx
Priority to ES439803A priority patent/ES439803A1/es
Priority to ES439804A priority patent/ES439804A1/es
Publication of SE384853B publication Critical patent/SE384853B/sv
Priority to US05/719,345 priority patent/US4145442A/en

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • A61K31/138Aryloxyalkylamines, e.g. propranolol, tamoxifen, phenoxybenzamine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C217/00Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
    • C07C217/02Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C217/04Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C217/28Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines
    • C07C217/30Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring
    • C07C217/32Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted
    • C07C217/34Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated having one amino group and at least two singly-bound oxygen atoms, with at least one being part of an etherified hydroxy group, bound to the carbon skeleton, e.g. ethers of polyhydroxy amines having the oxygen atom of at least one of the etherified hydroxy groups further bound to a carbon atom of a six-membered aromatic ring the six-membered aromatic ring or condensed ring system containing that ring being further substituted by halogen atoms, by trihalomethyl, nitro or nitroso groups, or by singly-bound oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • C07C271/10Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms
    • C07C271/16Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms with the nitrogen atoms of the carbamate groups bound to hydrogen atoms or to acyclic carbon atoms to carbon atoms of hydrocarbon radicals substituted by singly-bound oxygen atoms
SE7204321A 1969-04-23 1972-04-04 Forfarande for framstellning av nya aminer SE384853B (sv)

Priority Applications (25)

Application Number Priority Date Filing Date Title
SE7204321A SE384853B (sv) 1972-04-04 1972-04-04 Forfarande for framstellning av nya aminer
AR250907A AR204982A1 (es) 1972-04-04 1973-01-01 Procedimiento para preparar nuevos derivados de 1-fenoxi-2hidroxi-3-isopropilamina
ZA732119A ZA732119B (en) 1972-04-04 1973-03-27 New amines and process for their preparation
BE129334A BE797414A (fr) 1972-04-04 1973-03-28 Nouvelles amines et procede pour leur preparation
GB1584673A GB1421824A (en) 1972-04-04 1973-04-03 Aromatic hydroxy amines
ES413316A ES413316A1 (es) 1972-04-04 1973-04-03 Un procedimiento para la preparacion de aminas.
IE520/73A IE38302B1 (en) 1972-04-04 1973-04-03 Aromatic hydroxy amines
SU1907907A SU533336A3 (ru) 1972-04-04 1973-04-03 Способ получени аминопропанолов,их солей или оптически-активных антиподов
NL7304606A NL7304606A (sv) 1972-04-04 1973-04-03
CA167,812A CA1017755A (en) 1972-04-04 1973-04-03 Amines and process for their preparation
FI1026/73A FI63741C (fi) 1972-04-04 1973-04-03 Analogifoerfarande foer framstaellning av nya substituerade feoxipropanolaminer med hjaertselektiv beta-receptor blocke rade verkan
FR7312015A FR2179069B1 (sv) 1972-04-04 1973-04-03
US05/347,625 US3996382A (en) 1972-04-04 1973-04-04 Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases
JP48037950A JPS5924971B2 (ja) 1972-04-04 1973-04-04 新規なアミン類の製造方法
CH237976A CH587224A5 (sv) 1972-04-04 1973-04-04
NO1377/73A NO139167C (no) 1972-04-04 1973-04-04 Analogifremgangsmaate for fremstilling av nye terapeutisk aktive aminer
AT293873A AT321276B (de) 1972-04-04 1973-04-04 Verfahren zur Herstellung von neuen substituierten 3-Phenoxy-aminopropan-2-olen und deren Säureadditionssalzen
AT242774A AT321893B (de) 1969-04-23 1973-04-04 Verfahren zur herstellung von neuen substituierten 3-phenoxy-aminopropan-2-olen und deren säureaddiotionssalzen
BR732430A BR7302430D0 (pt) 1972-04-04 1973-04-04 Processo para preparacao de novas aminas; novas aminas e cesso para tratar doencas cardio-vasculares ompostos correspondentes, preparacoes farmaceuticas e pro
CH481673A CH587222A5 (sv) 1972-04-04 1973-04-04
DE2316727A DE2316727C3 (de) 1972-04-04 1973-04-04 o,p-Disubstituierte 3-Phenoxy-lalkylamino-propan-2-ole, Verfahren zu deren Herstellung und sie enthaltende Arzneimittel
CH238076A CH587225A5 (sv) 1972-04-04 1973-04-04
ES439803A ES439803A1 (es) 1972-04-04 1975-07-29 Un procedimiento para la preparacion de aminas.
ES439804A ES439804A1 (es) 1972-04-04 1975-07-29 Un procedimiento para la preparacion de aminas.
US05/719,345 US4145442A (en) 1972-04-04 1976-08-31 Phenoxy-hydroxypropylamines, their preparation, and method and pharmaceutical preparations for treating cardiovascular diseases

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
SE7204321A SE384853B (sv) 1972-04-04 1972-04-04 Forfarande for framstellning av nya aminer

Publications (1)

Publication Number Publication Date
SE384853B true SE384853B (sv) 1976-05-24

Family

ID=20263926

Family Applications (1)

Application Number Title Priority Date Filing Date
SE7204321A SE384853B (sv) 1969-04-23 1972-04-04 Forfarande for framstellning av nya aminer

Country Status (19)

Country Link
US (1) US3996382A (sv)
JP (1) JPS5924971B2 (sv)
AR (1) AR204982A1 (sv)
AT (1) AT321276B (sv)
BE (1) BE797414A (sv)
BR (1) BR7302430D0 (sv)
CA (1) CA1017755A (sv)
CH (3) CH587224A5 (sv)
DE (1) DE2316727C3 (sv)
ES (3) ES413316A1 (sv)
FI (1) FI63741C (sv)
FR (1) FR2179069B1 (sv)
GB (1) GB1421824A (sv)
IE (1) IE38302B1 (sv)
NL (1) NL7304606A (sv)
NO (1) NO139167C (sv)
SE (1) SE384853B (sv)
SU (1) SU533336A3 (sv)
ZA (1) ZA732119B (sv)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001161A (en) * 1984-01-10 1991-03-19 Aktiebolaget Hassle Pharmaceutical composition comprising metroprolol succinate

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HU169464B (sv) * 1974-02-20 1976-11-28
IL48309A (en) * 1974-10-25 1980-01-31 Robins Co Inc A H 1-aryloxy-4-amino-2-butanols and pharmaceutical compositions containing them
JPS5337126A (en) * 1976-09-17 1978-04-06 Nishida Marine Boiler Obtaining method of nickel from low grade nickel ore
JPS55161036A (en) * 1979-06-05 1980-12-15 Ooeyama Nickel Kk Nickel oxide ore smelting method
ZW9881A1 (en) * 1980-06-02 1981-12-23 Hoffmann La Roche Substituted phenoxyaminopropanol derivatives
FR2497194B1 (fr) * 1980-08-07 1985-06-14 Sandoz Sa Nouveaux composes phenoliques
CH643527A5 (en) * 1980-10-24 1984-06-15 Ciba Geigy Ag Process for the preparation of 1-alkylamino-3-(4-(2-lower alkoxy-ethyl)phenoxy)-2-propanols
DE3125636A1 (de) * 1981-06-30 1983-01-13 Merck Patent Gmbh, 6100 Darmstadt 1-(p-2-isopropoxyethoxymethyl-phenoxy)-3-isopropylamino-propan-2-ol zur senkung des augeninnendrucks und ophtalmikum, enthalten diese verbindung
US5064827A (en) * 1988-12-15 1991-11-12 Du Pont Merck Pharmaceutical Company Polyhydroxybenzyloxpropanolamines
US4959390A (en) * 1988-12-15 1990-09-25 E. I. Du Pont De Nemours And Company Polyhydroxybenzyloxypropanolamines
KR100469946B1 (ko) * 1998-04-14 2005-05-17 삼성정밀화학 주식회사 키랄(s)-2,3-치환-1-프로필아민유도체의제조방법
KR100469947B1 (ko) * 1998-04-14 2005-04-08 삼성정밀화학 주식회사 키랄(s)-3-아미노-1,2-프로판디올의제조방법
KR100489649B1 (ko) * 1998-04-14 2005-09-02 삼성정밀화학 주식회사 (s)-3-치환-2-히드록시프로필아민의제조방법
US20010018446A1 (en) 1999-09-23 2001-08-30 G.D. Searle & Co. Substituted N-Aliphatic-N-Aromatictertiary-Heteroalkylamines useful for inhibiting cholesteryl ester transfer protein activity

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1220440B (de) * 1962-02-14 1966-07-07 Sanol Arznei Schwarz Gmbh Verfahren zur Herstellung von Derivaten des 1-(o-Bromphenoxy)-2-hydroxy-3-amino-propans und deren Saeureadditionssalzen
US3459782A (en) * 1963-08-26 1969-08-05 Boehringer Sohn Ingelheim 1-substituted phenoxy-2-hydroxy-3-isopropylamino-propanes
CH465640A (de) * 1964-09-10 1968-11-30 Ciba Geigy Verfahren zur Herstellung neuer Amine
NL6504268A (sv) * 1965-04-03 1966-10-04
FR1547605A (fr) * 1967-09-27 1968-11-29 Amp Inc Connecteurs pour fusibles en cartouches
DK129447B (da) * 1967-12-18 1974-10-14 Boehringer Sohn Ingelheim Analogifremgangsmåde til fremstilling af racemiske eller optisk aktive 1-phenoxy-2-hydroxy-3-sek.-alkylaminopropaner eller syreadditionssalte heraf.
US3740444A (en) * 1968-01-25 1973-06-19 Boehringer Sohn Ingelheim Therapeutic compositions and method
GB1285038A (en) * 1969-02-21 1972-08-09 Ici Ltd Alkanolamine derivatives
US3639634A (en) * 1969-03-06 1972-02-01 Dow Chemical Co Cardiac antiarrhythmic method and composition employing alkylamino-alkoxyhalophenol compounds
JPS4943947B1 (sv) * 1970-04-03 1974-11-25
SE372762B (sv) * 1969-05-21 1975-01-13 Haessle Ab
SE354851B (sv) * 1970-02-18 1973-03-26 Haessle Ab
JPS5146113B2 (sv) * 1972-09-01 1976-12-07

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5001161A (en) * 1984-01-10 1991-03-19 Aktiebolaget Hassle Pharmaceutical composition comprising metroprolol succinate

Also Published As

Publication number Publication date
NO139167C (no) 1979-01-17
SU533336A3 (ru) 1976-10-25
CH587225A5 (sv) 1977-04-29
JPS4913129A (sv) 1974-02-05
NL7304606A (sv) 1973-10-08
ES439803A1 (es) 1977-04-16
ES413316A1 (es) 1976-06-01
US3996382A (en) 1976-12-07
FI63741B (fi) 1983-04-29
FR2179069A1 (sv) 1973-11-16
IE38302L (en) 1973-10-04
AR204982A1 (es) 1976-03-31
JPS5924971B2 (ja) 1984-06-13
GB1421824A (en) 1976-01-21
DE2316727A1 (de) 1974-01-10
DE2316727C3 (de) 1979-02-22
ZA732119B (en) 1974-01-30
BE797414A (fr) 1973-07-16
AT321276B (de) 1975-03-25
DE2316727B2 (de) 1978-06-22
ES439804A1 (es) 1977-04-16
CA1017755A (en) 1977-09-20
FR2179069B1 (sv) 1976-04-09
CH587224A5 (sv) 1977-04-29
IE38302B1 (en) 1978-02-15
FI63741C (fi) 1983-08-10
BR7302430D0 (pt) 1974-02-07
NO139167B (no) 1978-10-09
CH587222A5 (sv) 1977-04-29

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