US5292655A
(en)
*
|
1990-01-29 |
1994-03-08 |
Wille Jr John J |
Method for the formation of a histologically-complete skin substitute
|
GB9022545D0
(en)
|
1990-10-17 |
1990-11-28 |
Wellcome Found |
Culture medium
|
GB9022543D0
(en)
*
|
1990-10-17 |
1990-11-28 |
Wellcome Found |
Antibody production
|
JPH0789908B2
(ja)
*
|
1991-02-28 |
1995-10-04 |
倉敷紡績株式会社 |
動物細胞培養用無血清培地
|
DE4115722A1
(de)
*
|
1991-05-14 |
1992-11-19 |
Boehringer Mannheim Gmbh |
Serumfreies medium zur kultivierung von saeugerzellen
|
GB9118664D0
(en)
*
|
1991-08-30 |
1991-10-16 |
Celltech Ltd |
Cell culture
|
US6231881B1
(en)
|
1992-02-24 |
2001-05-15 |
Anton-Lewis Usala |
Medium and matrix for long-term proliferation of cells
|
US6352707B1
(en)
|
1992-02-24 |
2002-03-05 |
Anton-Lewis Usala |
Transplant encapsulation in a hydrogel matrix to obscure immune recognition
|
IL102929A
(en)
*
|
1992-08-24 |
1996-11-14 |
Interpharm Lab Ltd |
Serum-free medium for mammalian cells
|
DE4313620A1
(de)
*
|
1993-04-26 |
1994-10-27 |
Biotechnolog Forschung Gmbh |
Hamsterzellinien und Verfahren zur Glykoproteingewinnung
|
USH1532H
(en)
*
|
1993-11-03 |
1996-05-07 |
Genetics Institute, Inc. |
Adaption of mammalian cell lines to high cell densities
|
EP0653487A1
(de)
*
|
1993-11-07 |
1995-05-17 |
Ferruccio Dr. Messi |
Serum- und proteinfrei wachsende Zellen
|
US5856179A
(en)
|
1994-03-10 |
1999-01-05 |
Genentech, Inc. |
Polypeptide production in animal cell culture
|
US5512477A
(en)
*
|
1994-04-21 |
1996-04-30 |
Genzyme Corporation |
Serum-free medium supplement
|
US5698433A
(en)
*
|
1994-11-10 |
1997-12-16 |
Immuno Ag |
Method for producing influenza virus and vaccine
|
US5756341A
(en)
*
|
1994-11-10 |
1998-05-26 |
Immuno Ag |
Method for controlling the infectivity of viruses
|
US6146873A
(en)
*
|
1994-11-10 |
2000-11-14 |
Baxter Aktiengesellschaft |
Production of orthomyxoviruses in monkey kidney cells using protein-free media
|
US5753489A
(en)
*
|
1994-11-10 |
1998-05-19 |
Immuno Ag |
Method for producing viruses and vaccines in serum-free culture
|
US6656466B1
(en)
*
|
1995-06-06 |
2003-12-02 |
Genetech, Inc. |
Human tumor necrosis factor—immunoglobulin(TNFR1-IgG1) chimera composition
|
US5705364A
(en)
|
1995-06-06 |
1998-01-06 |
Genentech, Inc. |
Mammalian cell culture process
|
US5721121A
(en)
*
|
1995-06-06 |
1998-02-24 |
Genentech, Inc. |
Mammalian cell culture process for producing a tumor necrosis factor receptor immunoglobulin chimeric protein
|
WO1997033978A1
(en)
*
|
1996-03-12 |
1997-09-18 |
Life Technologies, Inc. |
Hematopoietic cell culture nutrient supplement
|
US6180404B1
(en)
*
|
1996-04-09 |
2001-01-30 |
The Board Of Trustees Of Southern Illinois University |
Cultural medium for maintaining neural cells in ambient atmosphere
|
AU4330597A
(en)
*
|
1996-08-30 |
1998-03-19 |
Life Technologies, Inc. |
Serum-free mammalian cell culture medium, and uses thereof
|
US20040171152A1
(en)
*
|
1996-10-10 |
2004-09-02 |
Invitrogen Corporation |
Animal cell culture media comprising non-animal or plant-derived nutrients
|
US6103529A
(en)
*
|
1996-10-10 |
2000-08-15 |
Life Technologies, Inc. |
Animal cell culture media comprising peptides derived from rice
|
US6692961B1
(en)
|
1996-10-11 |
2004-02-17 |
Invitrogen Corporation |
Defined systems for epithelial cell culture and use thereof
|
US20020012991A1
(en)
*
|
1997-04-07 |
2002-01-31 |
Florence Chua Nee Ho Kit Fong |
Cell culture media for enhanced protein production
|
US6475725B1
(en)
|
1997-06-20 |
2002-11-05 |
Baxter Aktiengesellschaft |
Recombinant cell clones having increased stability and methods of making and using the same
|
US6566118B1
(en)
*
|
1997-09-05 |
2003-05-20 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
US6995006B2
(en)
*
|
1997-09-05 |
2006-02-07 |
Targeted Genetics Corporation |
Methods for generating high titer helper-free preparations of released recombinant AAV vectors
|
WO1999057246A1
(en)
*
|
1998-05-01 |
1999-11-11 |
Life Technologies, Inc. |
Animal cell culture media comprising non-animal or plant-derived nutrients
|
US6528286B1
(en)
*
|
1998-05-29 |
2003-03-04 |
Genentech, Inc. |
Mammalian cell culture process for producing glycoproteins
|
US6406909B1
(en)
*
|
1998-07-10 |
2002-06-18 |
Chugai Seiyaku Kabushiki Kaisha |
Serum-free medium for culturing animal cells
|
US7294481B1
(en)
*
|
1999-01-05 |
2007-11-13 |
Immunex Corporation |
Method for producing recombinant proteins
|
ES2571230T3
(es)
|
1999-04-09 |
2016-05-24 |
Kyowa Hakko Kirin Co Ltd |
Procedimiento para controlar la actividad de una molécula inmunofuncional
|
US20060286668A1
(en)
*
|
1999-04-30 |
2006-12-21 |
Invitrogen Corporation |
Animal-cell culture media comprising non-animal or plant-derived nutrients
|
AT409379B
(de)
*
|
1999-06-02 |
2002-07-25 |
Baxter Ag |
Medium zur protein- und serumfreien kultivierung von zellen
|
PE20010288A1
(es)
|
1999-07-02 |
2001-03-07 |
Hoffmann La Roche |
Derivados de eritropoyetina
|
AU780810B2
(en)
*
|
1999-08-05 |
2005-04-21 |
Baxalta GmbH |
Recombinant stable cell clone, its production and use thereof
|
JP4668498B2
(ja)
|
1999-10-19 |
2011-04-13 |
協和発酵キリン株式会社 |
ポリペプチドの製造方法
|
KR20010056451A
(ko)
*
|
1999-12-15 |
2001-07-04 |
윤재승 |
아르기닌이 강화된 동물세포 배양용 배지 조성물
|
US6811776B2
(en)
|
2000-12-27 |
2004-11-02 |
The Regents Of The University Of Michigan |
Process for ex vivo formation of mammalian bone and uses thereof
|
EP1364002A2
(en)
*
|
2000-08-23 |
2003-11-26 |
Pfizer Products Inc. |
Process for the preparation of neutrophil inhibitory factor
|
US20020099183A1
(en)
*
|
2000-08-23 |
2002-07-25 |
Pluschkell Stefanie Beate |
Process for the preparation of neutrophil inhibitory factor
|
US6946292B2
(en)
|
2000-10-06 |
2005-09-20 |
Kyowa Hakko Kogyo Co., Ltd. |
Cells producing antibody compositions with increased antibody dependent cytotoxic activity
|
MXPA03005406A
(es)
|
2000-12-20 |
2003-09-25 |
Hoffmann La Roche |
Conjugados de eritropoyetina.
|
US6506576B2
(en)
|
2001-03-14 |
2003-01-14 |
Board Of Trustees Of The University Of Arkansas |
Serum-and steroid-free culture media for cerebellar granule neurons
|
KR20040065231A
(ko)
*
|
2001-11-28 |
2004-07-21 |
산도즈 게엠베하 |
세포 배양 방법
|
US20080254027A1
(en)
*
|
2002-03-01 |
2008-10-16 |
Bernett Matthew J |
Optimized CD5 antibodies and methods of using the same
|
US7317091B2
(en)
*
|
2002-03-01 |
2008-01-08 |
Xencor, Inc. |
Optimized Fc variants
|
US8093357B2
(en)
*
|
2002-03-01 |
2012-01-10 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US20070148171A1
(en)
*
|
2002-09-27 |
2007-06-28 |
Xencor, Inc. |
Optimized anti-CD30 antibodies
|
US8188231B2
(en)
|
2002-09-27 |
2012-05-29 |
Xencor, Inc. |
Optimized FC variants
|
US20040132101A1
(en)
|
2002-09-27 |
2004-07-08 |
Xencor |
Optimized Fc variants and methods for their generation
|
US20080260731A1
(en)
*
|
2002-03-01 |
2008-10-23 |
Bernett Matthew J |
Optimized antibodies that target cd19
|
JPWO2003084569A1
(ja)
|
2002-04-09 |
2005-08-11 |
協和醗酵工業株式会社 |
抗体組成物含有医薬
|
JP2005532057A
(ja)
|
2002-07-09 |
2005-10-27 |
バクスター・インターナショナル・インコーポレイテッド |
細胞を培養するための動物性タンパク質非含有培地
|
US7067279B1
(en)
|
2002-08-23 |
2006-06-27 |
Immunex Corporation |
Cell culture performance with betaine
|
US20060235208A1
(en)
*
|
2002-09-27 |
2006-10-19 |
Xencor, Inc. |
Fc variants with optimized properties
|
JP5116971B2
(ja)
|
2002-10-15 |
2013-01-09 |
インターセル アーゲー |
B群連鎖球菌の接着因子をコードする核酸、b群連鎖球菌の接着因子、およびその使用
|
DE10255508A1
(de)
*
|
2002-11-27 |
2004-06-17 |
Forschungszentrum Jülich GmbH |
Verfahren zur Kultivierung von Zellen zur Produktion von Substanzen
|
CN100402660C
(zh)
†
|
2002-12-23 |
2008-07-16 |
布里斯托尔-迈尔斯斯奎布公司 |
用于蛋白质生产的哺乳动物细胞培养方法中产物质量提高
|
GB0304799D0
(en)
|
2003-03-03 |
2003-04-09 |
Glaxosmithkline Biolog Sa |
Novel method
|
US20070275460A1
(en)
*
|
2003-03-03 |
2007-11-29 |
Xencor.Inc. |
Fc Variants With Optimized Fc Receptor Binding Properties
|
US8388955B2
(en)
*
|
2003-03-03 |
2013-03-05 |
Xencor, Inc. |
Fc variants
|
US8084582B2
(en)
|
2003-03-03 |
2011-12-27 |
Xencor, Inc. |
Optimized anti-CD20 monoclonal antibodies having Fc variants
|
US20090010920A1
(en)
|
2003-03-03 |
2009-01-08 |
Xencor, Inc. |
Fc Variants Having Decreased Affinity for FcyRIIb
|
EP1622941A2
(en)
*
|
2003-03-20 |
2006-02-08 |
ImClone Systems Incorporated |
Method of producing an antibody to epidermal growth factor receptor
|
US9051373B2
(en)
|
2003-05-02 |
2015-06-09 |
Xencor, Inc. |
Optimized Fc variants
|
AU2004263723B2
(en)
*
|
2003-08-08 |
2008-12-18 |
Medimmune Limited |
Myeloma cell culture in transferrin-free low iron medium
|
GB2404665B
(en)
*
|
2003-08-08 |
2005-07-06 |
Cambridge Antibody Tech |
Cell culture
|
CA2537462A1
(en)
*
|
2003-09-18 |
2005-03-31 |
Raven Biotechnologies, Inc. |
Cell culture media comprising fructose as the primary energy source
|
US9714282B2
(en)
|
2003-09-26 |
2017-07-25 |
Xencor, Inc. |
Optimized Fc variants and methods for their generation
|
US8101720B2
(en)
*
|
2004-10-21 |
2012-01-24 |
Xencor, Inc. |
Immunoglobulin insertions, deletions and substitutions
|
US20070264710A1
(en)
*
|
2003-10-09 |
2007-11-15 |
Hyea-Kyung Ahn |
Process for Purifying Human Thrombopoietin with High Content of Sialic Acid
|
AU2004280064A1
(en)
*
|
2003-10-09 |
2005-04-21 |
Kyowa Hakko Kirin Co., Ltd. |
Genomically modified cell neutralized to serum-free system
|
AU2004286938B2
(en)
*
|
2003-10-27 |
2011-06-30 |
Wyeth |
Removal of high molecular weight aggregates using hydroxyapatite chromatography
|
EP1697520A2
(en)
*
|
2003-12-22 |
2006-09-06 |
Xencor, Inc. |
Fc polypeptides with novel fc ligand binding sites
|
US7255288B2
(en)
*
|
2004-03-08 |
2007-08-14 |
Wan Shan Chan |
Aroma therapy for fountain
|
EP1737890A2
(en)
*
|
2004-03-24 |
2007-01-03 |
Xencor, Inc. |
Immunoglobulin variants outside the fc region
|
US20150010550A1
(en)
|
2004-07-15 |
2015-01-08 |
Xencor, Inc. |
OPTIMIZED Fc VARIANTS
|
TWI384069B
(zh)
|
2004-08-27 |
2013-02-01 |
Pfizer Ireland Pharmaceuticals |
多胜肽之製法
|
TWI374935B
(en)
|
2004-08-27 |
2012-10-21 |
Pfizer Ireland Pharmaceuticals |
Production of α-abeta
|
US7300773B2
(en)
|
2004-08-27 |
2007-11-27 |
Wyeth Research Ireland Limited |
Production of TNFR-Ig
|
US20060074225A1
(en)
*
|
2004-09-14 |
2006-04-06 |
Xencor, Inc. |
Monomeric immunoglobulin Fc domains
|
AU2011221414B2
(en)
*
|
2004-10-29 |
2012-09-20 |
Takeda Pharmaceutical Company Limited |
Animal Protein-Free Media for Cultivation of Cells
|
US20060094104A1
(en)
|
2004-10-29 |
2006-05-04 |
Leopold Grillberger |
Animal protein-free media for cultivation of cells
|
US8273553B2
(en)
*
|
2004-11-02 |
2012-09-25 |
Ares Trading S.A. |
Production of growth hormone in serum-free cell culture medium for mammalian cells
|
JP4833991B2
(ja)
|
2004-11-02 |
2011-12-07 |
アレス トレーディング ソシエテ アノニム |
哺乳動物細胞のための無血清細胞培養培地
|
MX2007005210A
(es)
*
|
2004-11-02 |
2007-05-11 |
Ares Trading Sa |
Medio de cultivo de celula libre de suero para las celulas de los mamiferos.
|
US8546543B2
(en)
|
2004-11-12 |
2013-10-01 |
Xencor, Inc. |
Fc variants that extend antibody half-life
|
US8367805B2
(en)
|
2004-11-12 |
2013-02-05 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
US20070135620A1
(en)
*
|
2004-11-12 |
2007-06-14 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
KR101027427B1
(ko)
|
2004-11-12 |
2011-04-11 |
젠코어 인코포레이티드 |
FcRn에 대하여 증가된 결합력을 갖는 Fc 변이체
|
US8802820B2
(en)
*
|
2004-11-12 |
2014-08-12 |
Xencor, Inc. |
Fc variants with altered binding to FcRn
|
WO2006076594A2
(en)
*
|
2005-01-12 |
2006-07-20 |
Xencor, Inc. |
Antibodies and fc fusion proteins with altered immunogenicity
|
JP5523674B2
(ja)
*
|
2005-02-11 |
2014-06-18 |
ノボ ノルディスク ヘルス ケア アクチェンゲゼルシャフト |
植物タンパク質加水分解産物を含有する血清フリーの細胞培養液におけるポリペプチドの生産
|
JP2006310392A
(ja)
*
|
2005-04-26 |
2006-11-09 |
Toshiba Corp |
電子ビーム描画方法及び電子ビーム描画装置
|
CA2610315A1
(en)
*
|
2005-06-03 |
2006-12-07 |
Biovitrum Ab (Publ) |
Process for cultivating animal cells comprising the feeding of plant-derived peptones
|
TWI369401B
(en)
*
|
2005-07-05 |
2012-08-01 |
Ares Trading Sa |
Serum-free culture medium for the production of recombinant gonadotropins
|
WO2007041635A2
(en)
*
|
2005-10-03 |
2007-04-12 |
Xencor, Inc. |
Fc variants with optimized fc receptor binding properties
|
JP4860703B2
(ja)
|
2005-10-06 |
2012-01-25 |
ゼンコー・インコーポレイテッド |
最適化された抗cd30抗体
|
EP2522717B1
(en)
|
2006-01-04 |
2014-04-02 |
Baxter International Inc |
Oligopeptide-free cell culture media
|
US20070190057A1
(en)
|
2006-01-23 |
2007-08-16 |
Jian Wu |
Methods for modulating mannose content of recombinant proteins
|
KR101495549B1
(ko)
|
2006-07-13 |
2015-02-25 |
와이어쓰 엘엘씨 |
당단백질의 생산
|
EP2054074B8
(en)
|
2006-08-04 |
2014-11-12 |
Prolong Pharmaceuticals, LLC |
Modified erythropoietin
|
PT2059536E
(pt)
|
2006-08-14 |
2014-04-14 |
Xencor Inc |
Anticorpos otimizados que visam cd19
|
EP2500415A1
(en)
*
|
2006-09-13 |
2012-09-19 |
Abbott Laboratories |
Cell culture improvements
|
US8911964B2
(en)
|
2006-09-13 |
2014-12-16 |
Abbvie Inc. |
Fed-batch method of making human anti-TNF-alpha antibody
|
TW201516149A
(zh)
*
|
2006-09-13 |
2015-05-01 |
Abbvie Inc |
細胞培養改良
|
WO2008036688A2
(en)
*
|
2006-09-18 |
2008-03-27 |
Xencor, Inc. |
Optimized antibodies that target hm1.24
|
ES2399940T3
(es)
|
2007-04-16 |
2013-04-04 |
Momenta Pharmaceuticals, Inc. |
Métodos relacionados con la glucosilación de la superficie celular
|
US9182467B2
(en)
*
|
2007-04-16 |
2015-11-10 |
Momenta Pharmaceuticals, Inc. |
Comparative analysis of protein conformations by using 2D NOESY NMR spectra
|
WO2008128222A1
(en)
*
|
2007-04-16 |
2008-10-23 |
Momenta Pharmaceuticals, Inc. |
Analysis of phosphorylated glycans, glycopeptides or glycoproteins by imac
|
TW200902708A
(en)
|
2007-04-23 |
2009-01-16 |
Wyeth Corp |
Methods of protein production using anti-senescence compounds
|
WO2008136398A1
(ja)
|
2007-04-26 |
2008-11-13 |
Chugai Seiyaku Kabushiki Kaisha |
高濃度アミノ酸含有培地を用いた細胞の培養方法
|
GB0710614D0
(en)
*
|
2007-06-04 |
2007-07-11 |
Lonza Biologics Plc |
Mammalian expression vector with a highly efficient secretory signal sequence
|
CN101319200B
(zh)
*
|
2007-06-08 |
2010-05-19 |
中国科学院大连化学物理研究所 |
一种适用于微囊化cho细胞的无血清培养基及其应用
|
US20100221823A1
(en)
*
|
2007-06-11 |
2010-09-02 |
Amgen Inc. |
Method for culturing mammalian cells to improve recombinant protein production
|
US7580304B2
(en)
*
|
2007-06-15 |
2009-08-25 |
United Memories, Inc. |
Multiple bus charge sharing
|
US20090042253A1
(en)
*
|
2007-08-09 |
2009-02-12 |
Wyeth |
Use of perfusion to enhance production of fed-batch cell culture in bioreactors
|
WO2009046978A1
(en)
*
|
2007-10-12 |
2009-04-16 |
F. Hoffmann-La Roche Ag |
Protein expression from multiple nucleic acids
|
SI2235059T1
(sl)
|
2007-12-26 |
2015-06-30 |
Xencor, Inc. |
Fc variante s spremenjeno vezjo na fcrn
|
DK2235197T3
(en)
*
|
2007-12-27 |
2017-10-09 |
Baxalta GmbH |
Methods of cell culture
|
DK2250251T3
(en)
*
|
2008-01-09 |
2018-01-22 |
Sartorius Stedim Cellca Gmbh |
Improved culture medium additive and method of using it
|
EP2257634A1
(en)
*
|
2008-03-12 |
2010-12-08 |
Wyeth LLC |
Method for identifying cells suitable for large-scale production of recombinant proteins
|
CN102007207B
(zh)
*
|
2008-04-18 |
2012-05-30 |
上海抗体药物国家工程研究中心有限公司 |
一种浓缩培养液及其使用方法
|
DE102008002210A1
(de)
|
2008-06-04 |
2009-12-10 |
Evonik Degussa Gmbh |
Verfahren zur fermentativen Herstellung von Erythropoietin
|
CA2739568C
(en)
*
|
2008-10-31 |
2015-12-01 |
Shujun Sun |
Purification of acidic proteins using ceramic hydroxyapatite chromatography
|
HUE026210T2
(en)
*
|
2008-11-12 |
2016-05-30 |
Baxalta Inc |
Procedure for serum-free, insulin-free VII. factor
|
EP2379710A1
(en)
*
|
2008-12-19 |
2011-10-26 |
Schering Corporation |
Feed supplement for mammalian cell culture and methods of use
|
CN102239173A
(zh)
|
2008-12-19 |
2011-11-09 |
动量制药公司 |
与修饰的聚糖相关的方法
|
DK2373783T3
(da)
|
2008-12-30 |
2018-01-29 |
Baxalta GmbH |
Fremgangsmåde til at forbedre cellevækst under anvendelse af alkyl-amin-n-oxid (aanox)
|
ES2440321T3
(es)
*
|
2009-02-27 |
2014-01-28 |
Novartis Ag |
Métodos para seleccionar células eucarióticas que expresan una proteína heteróloga
|
HUE045635T2
(hu)
|
2009-04-09 |
2020-01-28 |
Sartorius Stedim Cellca Gmbh |
Eljárás továbbfejlesztett egysejtes klónozásra
|
AU2010271178B2
(en)
|
2009-07-10 |
2015-10-22 |
Linzy O. Scott Iii |
Methods and compositions for treating thyroid-related medical conditions with reduced folates
|
BR122021005965B1
(pt)
|
2009-07-31 |
2022-01-25 |
Baxalta Incorporated |
Método para produzir uma composição de desintegrina e metaloproteinase com motivo trombospondina (adamts)
|
WO2011028952A1
(en)
|
2009-09-02 |
2011-03-10 |
Xencor, Inc. |
Compositions and methods for simultaneous bivalent and monovalent co-engagement of antigens
|
JP5728016B2
(ja)
|
2009-09-23 |
2015-06-03 |
ラチオファーマ ゲーエムベーハー |
組換えヒトエリスロポエチン(epo)を精製するためのプロセス、このようにして精製されたepoおよびこれを含む医薬組成物
|
DK2493922T3
(en)
|
2009-10-26 |
2017-04-24 |
Hoffmann La Roche |
Process for preparing a glycosylated immunoglobulin
|
US9045536B2
(en)
|
2009-12-23 |
2015-06-02 |
Merck Sharp & Dohme Corp. |
Cell line 3M
|
WO2011091078A2
(en)
|
2010-01-19 |
2011-07-28 |
Xencor, Inc. |
Antibody fc variants with enhanced complement activity
|
ES2533074T3
(es)
|
2010-04-26 |
2015-04-07 |
Novartis Ag |
Medio de cultivo celular mejorado
|
RU2577972C2
(ru)
|
2010-04-26 |
2016-03-20 |
Новартис Аг |
Способ получения рекомбинантного полипептида
|
CN102234627B
(zh)
*
|
2010-04-30 |
2015-06-03 |
中国科学院广州生物医药与健康研究院 |
一种培养基添加剂及其应用
|
TR201815211T4
(tr)
|
2010-07-08 |
2018-11-21 |
Baxalta GmbH |
Hücre kültüründe rekombinant adamts13 üretmeye yönelik yöntem.
|
SG187198A1
(en)
|
2010-08-05 |
2013-03-28 |
Amgen Inc |
Dipeptides to enhance yield and viability from cell cultures
|
ES2710543T3
(es)
|
2010-12-27 |
2019-04-25 |
Kyowa Hakko Kirin Co Ltd |
Método para preparar una disolución acuosa que contiene medio de cultivo y agente quelante
|
WO2012145682A1
(en)
*
|
2011-04-21 |
2012-10-26 |
Amgen Inc. |
A method for culturing mammalian cells to improve recombinant protein production
|
EP2702077A2
(en)
|
2011-04-27 |
2014-03-05 |
AbbVie Inc. |
Methods for controlling the galactosylation profile of recombinantly-expressed proteins
|
RU2580020C2
(ru)
|
2011-04-29 |
2016-04-10 |
Биокон Рисерч Лимитед |
Способ снижения гетерогенности антител и способ получения соответствующих антител
|
EP2732027B1
(en)
|
2011-07-12 |
2017-03-01 |
Foodchek Systems, Inc. |
Culture medium, method for culturing salmonella and e. coli and method for detecting salmonella and e. coli
|
EP2732024B1
(en)
*
|
2011-07-13 |
2017-03-01 |
Foodchek Systems, Inc. |
Culture medium, method for culturing listeria, and method for detecting listeria
|
US20140322758A1
(en)
|
2011-10-21 |
2014-10-30 |
Pfizer Inc. |
Addition of iron to improve cell culture
|
CA2864702A1
(en)
|
2012-02-22 |
2013-08-29 |
Amgen Inc. |
Autologous mammalian models derived from induced pluripotent stem cells and related methods
|
US9067990B2
(en)
|
2013-03-14 |
2015-06-30 |
Abbvie, Inc. |
Protein purification using displacement chromatography
|
US9181572B2
(en)
|
2012-04-20 |
2015-11-10 |
Abbvie, Inc. |
Methods to modulate lysine variant distribution
|
WO2013158279A1
(en)
|
2012-04-20 |
2013-10-24 |
Abbvie Inc. |
Protein purification methods to reduce acidic species
|
WO2013176754A1
(en)
|
2012-05-24 |
2013-11-28 |
Abbvie Inc. |
Novel purification of antibodies using hydrophobic interaction chromatography
|
AU2013309506A1
(en)
|
2012-09-02 |
2015-03-12 |
Abbvie Inc. |
Methods to control protein heterogeneity
|
US9512214B2
(en)
|
2012-09-02 |
2016-12-06 |
Abbvie, Inc. |
Methods to control protein heterogeneity
|
EP2711426B1
(en)
|
2012-09-24 |
2015-04-08 |
Lonza Biologics plc |
Expression vectors comprising chimeric cytomegalovirus promoter and enhancer sequences
|
AU2013381687A1
(en)
|
2013-03-12 |
2015-09-24 |
Abbvie Inc. |
Human antibodies that bind human TNF-alpha and methods of preparing the same
|
WO2014151878A2
(en)
|
2013-03-14 |
2014-09-25 |
Abbvie Inc. |
Methods for modulating protein glycosylation profiles of recombinant protein therapeutics using monosaccharides and oligosacharides
|
US9217168B2
(en)
|
2013-03-14 |
2015-12-22 |
Momenta Pharmaceuticals, Inc. |
Methods of cell culture
|
US8921526B2
(en)
|
2013-03-14 |
2014-12-30 |
Abbvie, Inc. |
Mutated anti-TNFα antibodies and methods of their use
|
US9017687B1
(en)
|
2013-10-18 |
2015-04-28 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same using displacement chromatography
|
ITTO20130493A1
(it)
|
2013-06-14 |
2014-12-15 |
Determinants Of Metabolism Res Lab S R L |
Composizione per l'eliminazione di animali molesti infestanti
|
JP6195191B2
(ja)
*
|
2013-08-08 |
2017-09-13 |
極東製薬工業株式会社 |
無タンパク質・無脂質培地馴化細胞株を用いた組換えタンパク質の製造方法
|
JP6190205B2
(ja)
*
|
2013-08-08 |
2017-08-30 |
極東製薬工業株式会社 |
無タンパク質・無脂質培地馴化細胞株、その製造方法及び培地
|
WO2015031686A1
(en)
|
2013-08-30 |
2015-03-05 |
Amgen Inc. |
High titer recombinant aav vector production in adherent and suspension cells
|
EP3052640A2
(en)
|
2013-10-04 |
2016-08-10 |
AbbVie Inc. |
Use of metal ions for modulation of protein glycosylation profiles of recombinant proteins
|
US8946395B1
(en)
|
2013-10-18 |
2015-02-03 |
Abbvie Inc. |
Purification of proteins using hydrophobic interaction chromatography
|
US9085618B2
(en)
|
2013-10-18 |
2015-07-21 |
Abbvie, Inc. |
Low acidic species compositions and methods for producing and using the same
|
US9181337B2
(en)
|
2013-10-18 |
2015-11-10 |
Abbvie, Inc. |
Modulated lysine variant species compositions and methods for producing and using the same
|
WO2015073884A2
(en)
|
2013-11-15 |
2015-05-21 |
Abbvie, Inc. |
Glycoengineered binding protein compositions
|
WO2016049367A1
(en)
*
|
2014-09-24 |
2016-03-31 |
Los Alamos National Security, Llc |
Multi-organ media compositions and methods of their use
|
ES2900331T3
(es)
|
2014-10-15 |
2022-03-16 |
Amgen Inc |
Elementos promotores y reguladores para mejorar la expresión de genes heterólogos en células hospederas
|
JP6432774B2
(ja)
*
|
2014-12-25 |
2018-12-05 |
江南化工株式会社 |
細胞賦活剤
|
IL260369B2
(en)
|
2016-01-06 |
2024-03-01 |
Lonza Ag |
Inhibition of protein breakdown for improved production
|
US10119117B2
(en)
|
2016-01-28 |
2018-11-06 |
Nanogen Pharmaceutical Biotechnology Co., Ltd |
Universal, glycosylation enhancer, completely chemically defined medium formulation
|
SG11201806335RA
(en)
*
|
2016-02-22 |
2018-09-27 |
Agency Science Tech & Res |
Cell culture medium
|
US10689873B2
(en)
|
2016-03-10 |
2020-06-23 |
Lonza Ltd |
Customizable facility
|
AU2017230823A1
(en)
|
2016-03-10 |
2018-09-27 |
Lonza Ltd |
Customizable facility
|
AU2017251360A1
(en)
|
2016-04-14 |
2018-11-01 |
Lonza Ltd |
Compositions and methods for the detection of host cell proteins
|
TWI734775B
(zh)
*
|
2016-04-26 |
2021-08-01 |
美商美國泰福生技股份有限公司 |
細胞培養基
|
IL294241B2
(en)
|
2016-05-03 |
2023-10-01 |
Lonza Ag |
Modulation of lipid metabolism for protein synthesis
|
BR112018075548A2
(pt)
|
2016-06-10 |
2019-04-09 |
Lonza Ltd |
método para estabilizar proteínas
|
EP3478821A1
(en)
|
2016-08-02 |
2019-05-08 |
Lonza Ltd |
Customizable facility
|
EP3485280A1
(en)
|
2016-08-12 |
2019-05-22 |
Lonza Ltd |
Proteomic analysis of host cell proteins
|
EP4186523A1
(en)
|
2016-09-16 |
2023-05-31 |
Leukocare AG |
A novel method for stabilization of a biopharmaceutical drug product during processing
|
CN106635958A
(zh)
*
|
2016-12-24 |
2017-05-10 |
严志海 |
一种中国仓鼠卵巢细胞培养基
|
JP7021245B2
(ja)
|
2017-03-10 |
2022-02-16 |
エフ.ホフマン-ラ ロシュ アーゲー |
多重特異性抗体を生産するための方法
|
JP2020523990A
(ja)
|
2017-06-16 |
2020-08-13 |
ロンザ リミテッドLonza Limited |
生物製剤の製造のためのユニバーサル自己調節性哺乳動物細胞株プラットフォーム
|
KR20200047702A
(ko)
|
2017-09-15 |
2020-05-07 |
브리스톨-마이어스 스큅 컴퍼니 |
관심 폴리펩티드 대규모 생산 동안의 온라인 바이오매스 정전용량 모니터링
|
CN111512161A
(zh)
|
2017-12-05 |
2020-08-07 |
隆萨有限公司 |
分析托酚酮的方法
|
ES2871818T3
(es)
|
2018-02-02 |
2021-11-02 |
Lonza Ag |
Métodos de selección celular y modificación del metabolismo celular
|
US20210010055A1
(en)
|
2018-03-16 |
2021-01-14 |
Bristol-Myers Squibb Company |
Metabolic enzyme activity and disulfide bond reduction during protein production
|
US20190367858A1
(en)
|
2018-06-01 |
2019-12-05 |
Lonza Ltd. |
Midscale Model For Organic Growth and Phasing
|
KR20210030949A
(ko)
|
2018-07-13 |
2021-03-18 |
론자 리미티드 |
내인성 단백질의 수준을 감소시켜 생물학적 생성물의 생산을 개선하는 방법
|
WO2020028616A1
(en)
|
2018-08-02 |
2020-02-06 |
Lonza Ltd |
Methods for manufacturing recombinant protein comprising a disulfide bond
|
CN110343666B
(zh)
*
|
2019-07-10 |
2023-05-30 |
通化东宝药业股份有限公司 |
一种cho细胞培养的补料培养基及其制备方法和应用
|
EP4058583A1
(en)
|
2019-11-14 |
2022-09-21 |
Lonza Ltd. |
Methods of cell selection
|
TW202128744A
(zh)
|
2019-12-06 |
2021-08-01 |
美商再生元醫藥公司 |
抗vegf蛋白組合物及其製備方法
|
JPWO2021193748A1
(xx)
*
|
2020-03-25 |
2021-09-30 |
|
|
KR20230124578A
(ko)
|
2020-12-22 |
2023-08-25 |
암젠 인크 |
세포 배양 방법
|
WO2023045140A1
(zh)
*
|
2021-09-26 |
2023-03-30 |
上海迈泰君奥生物技术有限公司 |
一种提高宿主细胞中抗体表达量的方法
|
CN113846051B
(zh)
*
|
2021-09-28 |
2023-12-01 |
无锡多宁生物科技有限公司 |
一种通用型化学成分限定cho细胞传代培养基及其应用
|