DE69226350T2 - Zellkulturverfahren und medium für das wachstum adhärenter tierzellen - Google Patents
Zellkulturverfahren und medium für das wachstum adhärenter tierzellenInfo
- Publication number
- DE69226350T2 DE69226350T2 DE69226350T DE69226350T DE69226350T2 DE 69226350 T2 DE69226350 T2 DE 69226350T2 DE 69226350 T DE69226350 T DE 69226350T DE 69226350 T DE69226350 T DE 69226350T DE 69226350 T2 DE69226350 T2 DE 69226350T2
- Authority
- DE
- Germany
- Prior art keywords
- total
- cells
- animal cells
- nutrient medium
- adherent animal
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 230000001464 adherent effect Effects 0.000 title abstract 3
- 238000004113 cell culture Methods 0.000 title 1
- 235000015097 nutrients Nutrition 0.000 abstract 4
- 150000001413 amino acids Chemical class 0.000 abstract 3
- 210000004102 animal cell Anatomy 0.000 abstract 2
- 210000004027 cell Anatomy 0.000 abstract 2
- 210000004978 chinese hamster ovary cell Anatomy 0.000 abstract 2
- 229910001410 inorganic ion Inorganic materials 0.000 abstract 2
- VEXZGXHMUGYJMC-UHFFFAOYSA-M Chloride anion Chemical compound [Cl-] VEXZGXHMUGYJMC-UHFFFAOYSA-M 0.000 abstract 1
- 241000699800 Cricetinae Species 0.000 abstract 1
- 241000282414 Homo sapiens Species 0.000 abstract 1
- 241000699666 Mus <mouse, genus> Species 0.000 abstract 1
- 241000700159 Rattus Species 0.000 abstract 1
- FKNQFGJONOIPTF-UHFFFAOYSA-N Sodium cation Chemical compound [Na+] FKNQFGJONOIPTF-UHFFFAOYSA-N 0.000 abstract 1
- 230000002776 aggregation Effects 0.000 abstract 1
- 238000004220 aggregation Methods 0.000 abstract 1
- 210000004962 mammalian cell Anatomy 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 229910001415 sodium ion Inorganic materials 0.000 abstract 1
- 239000000725 suspension Substances 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/0018—Culture media for cell or tissue culture
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2500/00—Specific components of cell culture medium
- C12N2500/05—Inorganic components
- C12N2500/10—Metals; Metal chelators
- C12N2500/12—Light metals, i.e. alkali, alkaline earth, Be, Al, Mg
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Health & Medical Sciences (AREA)
- Biomedical Technology (AREA)
- Biotechnology (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Cell Biology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB919118664A GB9118664D0 (en) | 1991-08-30 | 1991-08-30 | Cell culture |
| PCT/GB1992/001571 WO1993005145A1 (en) | 1991-08-30 | 1992-08-28 | Cell culture process and medium for the growth of adherent animal cells |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69226350D1 DE69226350D1 (de) | 1998-08-27 |
| DE69226350T2 true DE69226350T2 (de) | 1999-01-07 |
Family
ID=10700726
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69226350T Expired - Lifetime DE69226350T2 (de) | 1991-08-30 | 1992-08-28 | Zellkulturverfahren und medium für das wachstum adhärenter tierzellen |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US5871999A (de) |
| EP (1) | EP0555454B1 (de) |
| JP (1) | JP3116066B2 (de) |
| AT (1) | ATE168717T1 (de) |
| DE (1) | DE69226350T2 (de) |
| DK (1) | DK0555454T3 (de) |
| ES (1) | ES2118827T3 (de) |
| GB (1) | GB9118664D0 (de) |
| WO (1) | WO1993005145A1 (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| USH1532H (en) * | 1993-11-03 | 1996-05-07 | Genetics Institute, Inc. | Adaption of mammalian cell lines to high cell densities |
| CN104593277A (zh) | 2004-03-05 | 2015-05-06 | 帝斯曼知识产权资产管理有限公司 | 用于通过连续灌注和交互切向流来培养细胞的方法 |
| TWI374935B (en) | 2004-08-27 | 2012-10-21 | Pfizer Ireland Pharmaceuticals | Production of α-abeta |
| US7300773B2 (en) | 2004-08-27 | 2007-11-27 | Wyeth Research Ireland Limited | Production of TNFR-Ig |
| TWI384069B (zh) * | 2004-08-27 | 2013-02-01 | Pfizer Ireland Pharmaceuticals | 多胜肽之製法 |
| BRPI0714347A2 (pt) | 2006-07-14 | 2013-05-07 | Dsm Ip Assets Bv | processo aperfeiÇoado para o cultivo de cÉlulas |
| PT2563906T (pt) | 2010-04-26 | 2018-02-16 | Novartis Ag | Processo para cultivo de células cho |
| EP2563904B1 (de) | 2010-04-26 | 2015-01-21 | Novartis AG | Verbessertes zellkulturmedium |
| EP3599276A1 (de) | 2010-04-26 | 2020-01-29 | Novartis AG | Verbessertes zellkulturmedium |
| DK2837680T3 (da) | 2011-07-01 | 2020-04-27 | Amgen Inc | Mammaliacellekultur |
| US11505784B2 (en) * | 2015-04-01 | 2022-11-22 | Boehringer Ingelheim International Gmbh | Cell culture medium |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB852052A (en) * | 1958-01-07 | 1960-10-19 | Research Corp | Propagation of mammalian cells |
| US3850748A (en) * | 1973-06-28 | 1974-11-26 | Lilly Co Eli | Method of producing animal cells in suspension culture |
| US4124448A (en) * | 1976-04-09 | 1978-11-07 | The Regents Of The University Of Minnesota | Process for the large scale production of human growth hormone by serial secondary suspension culture |
| GB8516415D0 (en) * | 1985-06-28 | 1985-07-31 | Celltech Ltd | Culture of animal cells |
| EP0343635B1 (de) * | 1988-05-25 | 1994-08-24 | Teijin Limited | Verfahren zur kontinuierlichen Züchtung von haftenden tierischen Zellen |
| US4896069A (en) * | 1988-05-27 | 1990-01-23 | Makash - Advanced Piezo Technology | Piezoelectric switch |
| US5122469A (en) * | 1990-10-03 | 1992-06-16 | Genentech, Inc. | Method for culturing Chinese hamster ovary cells to improve production of recombinant proteins |
| GB9022545D0 (en) * | 1990-10-17 | 1990-11-28 | Wellcome Found | Culture medium |
-
1991
- 1991-08-30 GB GB919118664A patent/GB9118664D0/en active Pending
-
1992
- 1992-08-28 ES ES92918738T patent/ES2118827T3/es not_active Expired - Lifetime
- 1992-08-28 AT AT92918738T patent/ATE168717T1/de active
- 1992-08-28 DE DE69226350T patent/DE69226350T2/de not_active Expired - Lifetime
- 1992-08-28 DK DK92918738T patent/DK0555454T3/da active
- 1992-08-28 EP EP92918738A patent/EP0555454B1/de not_active Expired - Lifetime
- 1992-08-28 WO PCT/GB1992/001571 patent/WO1993005145A1/en active IP Right Grant
- 1992-08-28 JP JP05505023A patent/JP3116066B2/ja not_active Expired - Lifetime
-
1994
- 1994-12-13 US US08/355,103 patent/US5871999A/en not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| ATE168717T1 (de) | 1998-08-15 |
| DE69226350D1 (de) | 1998-08-27 |
| EP0555454A1 (de) | 1993-08-18 |
| JP3116066B2 (ja) | 2000-12-11 |
| GB9118664D0 (en) | 1991-10-16 |
| ES2118827T3 (es) | 1998-10-01 |
| EP0555454B1 (de) | 1998-07-22 |
| DK0555454T3 (da) | 1998-10-26 |
| JPH06502551A (ja) | 1994-03-24 |
| WO1993005145A1 (en) | 1993-03-18 |
| US5871999A (en) | 1999-02-16 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: LONZA GROUP AG, ZUERICH, CH |
|
| R071 | Expiry of right |
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