DE69017793D1 - Produktion von menschlichen Nervenwachstumsfaktoren. - Google Patents

Produktion von menschlichen Nervenwachstumsfaktoren.

Info

Publication number
DE69017793D1
DE69017793D1 DE69017793T DE69017793T DE69017793D1 DE 69017793 D1 DE69017793 D1 DE 69017793D1 DE 69017793 T DE69017793 T DE 69017793T DE 69017793 T DE69017793 T DE 69017793T DE 69017793 D1 DE69017793 D1 DE 69017793D1
Authority
DE
Germany
Prior art keywords
cysteine residue
human ngf
animal cell
production
growth factors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69017793T
Other languages
English (en)
Other versions
DE69017793T2 (de
Inventor
Atsushi Kakinuma
Kazuo Nakahama
Koji Yoshimura
Reiko Sasada
Yoshihiko Kaisho
Makoto Iwane
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of DE69017793D1 publication Critical patent/DE69017793D1/de
Publication of DE69017793T2 publication Critical patent/DE69017793T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DE69017793T 1989-08-21 1990-08-17 Produktion von menschlichen Nervenwachstumsfaktoren. Expired - Fee Related DE69017793T2 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP21298089 1989-08-21
JP32819889 1989-12-20
JP9625290 1990-04-13
JP14739290 1990-06-07

Publications (2)

Publication Number Publication Date
DE69017793D1 true DE69017793D1 (de) 1995-04-20
DE69017793T2 DE69017793T2 (de) 1995-08-24

Family

ID=27468414

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69017793T Expired - Fee Related DE69017793T2 (de) 1989-08-21 1990-08-17 Produktion von menschlichen Nervenwachstumsfaktoren.

Country Status (5)

Country Link
EP (1) EP0414151B1 (de)
AT (1) ATE119938T1 (de)
CA (1) CA2023654A1 (de)
DE (1) DE69017793T2 (de)
DK (1) DK0414151T3 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
US5389529A (en) * 1991-06-12 1995-02-14 Regeneron Pharmaceuticals, Inc. Modified lamβ signal sequence and processes for producing recombinant neurotrophins
DE4139000A1 (de) * 1991-11-27 1993-06-03 Boehringer Mannheim Gmbh Verfahren zur gentechnologischen herstellung von biologisch aktivem ss-ngf
US6291247B1 (en) 1994-05-11 2001-09-18 Queen's University At Kingston Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity
NZ335207A (en) * 1996-11-15 2000-09-29 Genentech Inc Process to isolate recombinant human neurotrophin using hydrophobic chromatography resin
KR20190140090A (ko) 2007-07-09 2019-12-18 제넨테크, 인크. 폴리펩티드의 재조합 생산 동안의 디술피드 결합 환원의 방지

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161152C (da) * 1983-03-03 1991-11-11 Genentech Inc Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat

Also Published As

Publication number Publication date
EP0414151A1 (de) 1991-02-27
EP0414151B1 (de) 1995-03-15
ATE119938T1 (de) 1995-04-15
DE69017793T2 (de) 1995-08-24
CA2023654A1 (en) 1991-02-22
DK0414151T3 (da) 1995-05-22

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee