ATE119938T1 - Produktion von menschlichen nervenwachstumsfaktoren. - Google Patents

Produktion von menschlichen nervenwachstumsfaktoren.

Info

Publication number
ATE119938T1
ATE119938T1 AT90115815T AT90115815T ATE119938T1 AT E119938 T1 ATE119938 T1 AT E119938T1 AT 90115815 T AT90115815 T AT 90115815T AT 90115815 T AT90115815 T AT 90115815T AT E119938 T1 ATE119938 T1 AT E119938T1
Authority
AT
Austria
Prior art keywords
cysteine residue
human ngf
animal cell
production
growth factors
Prior art date
Application number
AT90115815T
Other languages
English (en)
Inventor
Atsushi Kakinuma
Kazuo Nakahama
Koji Yoshimura
Reiko Sasada
Yoshihiko Kaisho
Makoto Iwane
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Application granted granted Critical
Publication of ATE119938T1 publication Critical patent/ATE119938T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/475—Growth factors; Growth regulators
    • C07K14/48—Nerve growth factor [NGF]

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Zoology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Toxicology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
AT90115815T 1989-08-21 1990-08-17 Produktion von menschlichen nervenwachstumsfaktoren. ATE119938T1 (de)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP21298089 1989-08-21
JP32819889 1989-12-20
JP9625290 1990-04-13
JP14739290 1990-06-07

Publications (1)

Publication Number Publication Date
ATE119938T1 true ATE119938T1 (de) 1995-04-15

Family

ID=27468414

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90115815T ATE119938T1 (de) 1989-08-21 1990-08-17 Produktion von menschlichen nervenwachstumsfaktoren.

Country Status (5)

Country Link
EP (1) EP0414151B1 (de)
AT (1) ATE119938T1 (de)
CA (1) CA2023654A1 (de)
DE (1) DE69017793T2 (de)
DK (1) DK0414151T3 (de)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5180820A (en) * 1989-08-30 1993-01-19 Barde Yves Alain Brain-derived neurotrophic factor
US5389529A (en) * 1991-06-12 1995-02-14 Regeneron Pharmaceuticals, Inc. Modified lamβ signal sequence and processes for producing recombinant neurotrophins
DE4139000A1 (de) * 1991-11-27 1993-06-03 Boehringer Mannheim Gmbh Verfahren zur gentechnologischen herstellung von biologisch aktivem ss-ngf
US6291247B1 (en) 1994-05-11 2001-09-18 Queen's University At Kingston Methods of screening for factors that disrupt neurotrophin conformation and reduce neurotrophin biological activity
TR199901734T2 (xx) 1996-11-15 2000-01-21 Genentech, Inc. N�rotrofinlerin ar�t�lmas�.
SI2586788T1 (en) 2007-07-09 2018-07-31 Genentech, Inc. Prevention of the reduction of the disulfide bond during the recombinant production of polypeptides
CN114729330A (zh) * 2021-07-30 2022-07-08 成都优洛生物科技有限公司 一种重组cho细胞、其构建方法、利用其的检测系统和方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK161152C (da) * 1983-03-03 1991-11-11 Genentech Inc Polypeptid med egenskaber som human beta-nervevaekstfaktor og fremgangsmaade til fremstilling deraf, dna-isolat omfattende en sekvens som koder for polypeptidet, replicerbar udtrykkelsesvektor for dna-sekvensen, rekombinant vaertscelle transformeret med vektoren, farmaceutisk praeparat indeholdende polypeptidet og fremg. der omfatter anvendelsen af polypeptidet til fremst. af et farmaceutisk praeparat

Also Published As

Publication number Publication date
CA2023654A1 (en) 1991-02-22
EP0414151B1 (de) 1995-03-15
DE69017793T2 (de) 1995-08-24
EP0414151A1 (de) 1991-02-27
DE69017793D1 (de) 1995-04-20
DK0414151T3 (da) 1995-05-22

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Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties
EEWE Authorization for restitution
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee