ATE46348T1 - Neue, physiologisch aktive polypeptide und deren herstellungsverfahren. - Google Patents
Neue, physiologisch aktive polypeptide und deren herstellungsverfahren.Info
- Publication number
- ATE46348T1 ATE46348T1 AT84307098T AT84307098T ATE46348T1 AT E46348 T1 ATE46348 T1 AT E46348T1 AT 84307098 T AT84307098 T AT 84307098T AT 84307098 T AT84307098 T AT 84307098T AT E46348 T1 ATE46348 T1 AT E46348T1
- Authority
- AT
- Austria
- Prior art keywords
- amino acid
- physiologically active
- production processes
- polypeptide
- active polypeptides
- Prior art date
Links
- 108090000765 processed proteins & peptides Proteins 0.000 title abstract 5
- 229920001184 polypeptide Polymers 0.000 title abstract 4
- 102000004196 processed proteins & peptides Human genes 0.000 title abstract 4
- 108090000623 proteins and genes Proteins 0.000 abstract 3
- 125000000539 amino acid group Chemical group 0.000 abstract 2
- 102000008070 Interferon-gamma Human genes 0.000 abstract 1
- 108010074328 Interferon-gamma Proteins 0.000 abstract 1
- 125000003275 alpha amino acid group Chemical group 0.000 abstract 1
- 230000000840 anti-viral effect Effects 0.000 abstract 1
- 239000013604 expression vector Substances 0.000 abstract 1
- 229940044627 gamma-interferon Drugs 0.000 abstract 1
- 125000004435 hydrogen atom Chemical group [H]* 0.000 abstract 1
- 125000002073 methionyl group Chemical group 0.000 abstract 1
- 244000005700 microbiome Species 0.000 abstract 1
- 102000004169 proteins and genes Human genes 0.000 abstract 1
- 230000009466 transformation Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/70—Vectors or expression systems specially adapted for E. coli
- C12N15/72—Expression systems using regulatory sequences derived from the lac-operon
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/52—Cytokines; Lymphokines; Interferons
- C07K14/555—Interferons [IFN]
- C07K14/57—IFN-gamma
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
- C12N15/67—General methods for enhancing the expression
- C12N15/69—Increasing the copy number of the vector
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- General Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- Wood Science & Technology (AREA)
- Biophysics (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Microbiology (AREA)
- Physics & Mathematics (AREA)
- Plant Pathology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Toxicology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Virology (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Saccharide Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP58194539A JPH0788398B2 (ja) | 1983-10-17 | 1983-10-17 | 新規生理活性ポリペプチドおよびその製造法 |
| EP84307098A EP0145174B1 (de) | 1983-10-17 | 1984-10-16 | Neue, physiologisch aktive Polypeptide und deren Herstellungsverfahren |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE46348T1 true ATE46348T1 (de) | 1989-09-15 |
Family
ID=16326212
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT84307098T ATE46348T1 (de) | 1983-10-17 | 1984-10-16 | Neue, physiologisch aktive polypeptide und deren herstellungsverfahren. |
Country Status (4)
| Country | Link |
|---|---|
| EP (1) | EP0145174B1 (de) |
| JP (1) | JPH0788398B2 (de) |
| AT (1) | ATE46348T1 (de) |
| DE (1) | DE3479734D1 (de) |
Families Citing this family (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS6054685A (ja) * | 1983-09-02 | 1985-03-29 | Suntory Ltd | 改良発現ベクタ−およびその利用 |
| US4855238A (en) * | 1983-12-16 | 1989-08-08 | Genentech, Inc. | Recombinant gamma interferons having enhanced stability and methods therefor |
| JPS60172999A (ja) * | 1983-12-20 | 1985-09-06 | Suntory Ltd | 新規な塩基性ポリペプチドおよびその製造法 |
| US4758656A (en) * | 1983-12-26 | 1988-07-19 | Kyowa Hakko Kogyo Co., Ltd. | Novel human interferon-gamma polypeptide derivative |
| GB2164650A (en) * | 1984-09-25 | 1986-03-26 | Fujisawa Pharmaceutical Co | Process for production of y-interferon |
| GB8619725D0 (en) * | 1986-08-13 | 1986-09-24 | Hoffmann La Roche | Homogenous interferon fragments |
| JP4125784B2 (ja) * | 1995-10-20 | 2008-07-30 | ユニバーシティ・オブ・ネブラスカ・ボード・オブ・リージェンツ | 抗原提示細胞により仲介される免疫応答を高めるための組成物および方法 |
| BR0015506A (pt) | 1999-11-12 | 2002-07-23 | Maxygen Holdings Ltd | Conjugados de interferon gama, métodos para sua preparação, composições farmacêuticas que compreendem ás moléculas e seu uso no tratamento de doenças |
| YU32402A (sh) | 1999-11-12 | 2005-03-15 | Maxygen Holdings Ltd. | Konjugati gama interferona |
| US6958388B2 (en) | 2001-04-06 | 2005-10-25 | Maxygen, Aps | Interferon gamma polypeptide variants |
| US7038015B2 (en) | 2001-04-06 | 2006-05-02 | Maxygen Holdings, Ltd. | Interferon gamma polypeptide variants |
| WO2004005341A2 (en) | 2002-07-03 | 2004-01-15 | Maxygen Holdings Ltd. | Full-length interferon gamma polypeptide variants |
| JP6909762B2 (ja) | 2018-07-23 | 2021-07-28 | 株式会社Kokusai Electric | 半導体装置の製造方法、基板処理方法、基板処理装置、およびプログラム |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AU561343B2 (en) * | 1981-10-19 | 1987-05-07 | Genentech Inc. | Human immune interferon by recombinant dna |
| JPS58110548A (ja) * | 1981-12-24 | 1983-07-01 | Asahi Chem Ind Co Ltd | 新規な生理活性ペプチド |
| ZA831094B (en) * | 1982-02-22 | 1983-11-30 | Biogen Nv | Dna sequences,recombinant dna molecules and processes for producing human immune interferon-like polypeptides |
| IL68100A0 (en) * | 1982-03-24 | 1983-06-15 | Takeda Chemical Industries Ltd | Novel dna and use thereof |
-
1983
- 1983-10-17 JP JP58194539A patent/JPH0788398B2/ja not_active Expired - Lifetime
-
1984
- 1984-10-16 DE DE8484307098T patent/DE3479734D1/de not_active Expired
- 1984-10-16 AT AT84307098T patent/ATE46348T1/de not_active IP Right Cessation
- 1984-10-16 EP EP84307098A patent/EP0145174B1/de not_active Expired
Also Published As
| Publication number | Publication date |
|---|---|
| DE3479734D1 (en) | 1989-10-19 |
| JPS6084298A (ja) | 1985-05-13 |
| JPH0788398B2 (ja) | 1995-09-27 |
| EP0145174A1 (de) | 1985-06-19 |
| EP0145174B1 (de) | 1989-09-13 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification | ||
| REN | Ceased due to non-payment of the annual fee |