JPS6427495A - Novel physiologically active polypeptide - Google Patents

Novel physiologically active polypeptide

Info

Publication number
JPS6427495A
JPS6427495A JP62182321A JP18232187A JPS6427495A JP S6427495 A JPS6427495 A JP S6427495A JP 62182321 A JP62182321 A JP 62182321A JP 18232187 A JP18232187 A JP 18232187A JP S6427495 A JPS6427495 A JP S6427495A
Authority
JP
Japan
Prior art keywords
polypeptide
physiologically active
active polypeptide
novel
cultured
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
JP62182321A
Other languages
Japanese (ja)
Inventor
Satoshi Nakamura
Tsukio Sakugi
Kazuo Kitai
Yataro Ichikawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Teijin Ltd
Original Assignee
Teijin Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Teijin Ltd filed Critical Teijin Ltd
Priority to JP62182321A priority Critical patent/JPS6427495A/en
Publication of JPS6427495A publication Critical patent/JPS6427495A/en
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/525—Tumour necrosis factor [TNF]

Abstract

PURPOSE:To produce a novel antitumor polypeptide, by forming a DNA coding a physiologically active polypeptide containing a specific amino acid sequence or a polypeptide having Met bonded to the amino terminal of the above polypeptide. CONSTITUTION:A recombinant plasmid containing a DNA region coding a specific physiologically active polypeptide or a polypeptide having Met bonded to the amino terminal of the above polypeptide is prepared. A recombinant bacterial cell transformed with the recombinant plasmid is cultured to effect the formation and accumulation of a novel physiologically active polypeptide in the cultured product. The physiologically active polypeptide is separated from the obtained cultured product. An excellent pharmaceutical composition having antitumor activity can be produced by the use of the polypeptide.
JP62182321A 1987-07-23 1987-07-23 Novel physiologically active polypeptide Pending JPS6427495A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
JP62182321A JPS6427495A (en) 1987-07-23 1987-07-23 Novel physiologically active polypeptide

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP62182321A JPS6427495A (en) 1987-07-23 1987-07-23 Novel physiologically active polypeptide

Publications (1)

Publication Number Publication Date
JPS6427495A true JPS6427495A (en) 1989-01-30

Family

ID=16116263

Family Applications (1)

Application Number Title Priority Date Filing Date
JP62182321A Pending JPS6427495A (en) 1987-07-23 1987-07-23 Novel physiologically active polypeptide

Country Status (1)

Country Link
JP (1) JPS6427495A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10640142B2 (en) 2015-04-24 2020-05-05 Oiles Corporation Multilayered sliding member and rack-and-pinion type steering apparatus for automobile using the same

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US10640142B2 (en) 2015-04-24 2020-05-05 Oiles Corporation Multilayered sliding member and rack-and-pinion type steering apparatus for automobile using the same

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