DK1183251T3 - Indolylpiperidinderivater som antihistamin- og antiallergimidler - Google Patents

Indolylpiperidinderivater som antihistamin- og antiallergimidler

Info

Publication number
DK1183251T3
DK1183251T3 DK00940296T DK00940296T DK1183251T3 DK 1183251 T3 DK1183251 T3 DK 1183251T3 DK 00940296 T DK00940296 T DK 00940296T DK 00940296 T DK00940296 T DK 00940296T DK 1183251 T3 DK1183251 T3 DK 1183251T3
Authority
DK
Denmark
Prior art keywords
antihistamine
allergy agents
indolylpiperidine derivatives
indolylpiperidine
derivatives
Prior art date
Application number
DK00940296T
Other languages
Danish (da)
English (en)
Inventor
Santacana Lluis Pages
Pou Silvia Fonquerna
Duran Carles Puig
Forner Dolors Fernandez
Original Assignee
Almirall Prodesfarma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Almirall Prodesfarma Sa filed Critical Almirall Prodesfarma Sa
Application granted granted Critical
Publication of DK1183251T3 publication Critical patent/DK1183251T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/02—Nasal agents, e.g. decongestants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/04—Drugs for disorders of the respiratory system for throat disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00—Drugs for dermatological disorders
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Pulmonology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Otolaryngology (AREA)
  • Immunology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Dermatology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DK00940296T 1999-06-04 2000-05-31 Indolylpiperidinderivater som antihistamin- og antiallergimidler DK1183251T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
ES009901232A ES2165274B1 (es) 1999-06-04 1999-06-04 Nuevos derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
PCT/EP2000/005010 WO2000075130A1 (en) 1999-06-04 2000-05-31 Indolylpiperidine derivatives as antihistaminic and antiallergic agents

Publications (1)

Publication Number Publication Date
DK1183251T3 true DK1183251T3 (da) 2004-06-07

Family

ID=8308707

Family Applications (1)

Application Number Title Priority Date Filing Date
DK00940296T DK1183251T3 (da) 1999-06-04 2000-05-31 Indolylpiperidinderivater som antihistamin- og antiallergimidler

Country Status (35)

Country Link
US (1) US6683096B2 (uk)
EP (1) EP1183251B1 (uk)
JP (1) JP2003501424A (uk)
KR (1) KR100683454B1 (uk)
CN (1) CN1191246C (uk)
AR (1) AR029640A1 (uk)
AT (1) ATE259362T1 (uk)
AU (1) AU773164B2 (uk)
BG (1) BG106168A (uk)
BR (1) BR0011340A (uk)
CA (1) CA2375985A1 (uk)
CO (1) CO5180556A1 (uk)
CZ (1) CZ20014334A3 (uk)
DE (1) DE60008239T2 (uk)
DK (1) DK1183251T3 (uk)
EE (1) EE04717B1 (uk)
ES (2) ES2165274B1 (uk)
HK (1) HK1040990A1 (uk)
HU (1) HUP0203320A3 (uk)
IL (1) IL146629A0 (uk)
MX (1) MXPA01012425A (uk)
MY (1) MY127033A (uk)
NO (1) NO20015897L (uk)
NZ (1) NZ515649A (uk)
PE (1) PE20010208A1 (uk)
PL (1) PL196774B1 (uk)
PT (1) PT1183251E (uk)
RU (1) RU2246493C2 (uk)
SI (1) SI1183251T1 (uk)
SK (1) SK17042001A3 (uk)
TR (1) TR200103490T2 (uk)
TW (1) TWI226889B (uk)
UA (1) UA72517C2 (uk)
WO (1) WO2000075130A1 (uk)
ZA (1) ZA200109676B (uk)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6864219B2 (en) 2000-01-17 2005-03-08 Bayer Aktiengesellschaft Substituted aryl ketones
ES2172436B1 (es) 2000-10-31 2004-01-16 Almirall Prodesfarma Sa Derivados de indolilpiperidina como agentes antihistaminicos y antialergicos.
AU2002243394A1 (en) * 2000-11-16 2002-06-24 Wyeth Aryloxy piperidinyl derivatives for the treatment of depression
ES2201899B1 (es) * 2002-04-01 2005-06-01 Almirall Prodesfarma, S.A. Derivados de la azaindolilpiperidina como agentes antihistaminicos y antialergicos.
ES2201907B1 (es) * 2002-05-29 2005-06-01 Almirall Prodesfarma, S.A. Nuevos derivados de indolilpiperidina como potentes agentes antihistaminicos y antialergicos.
CN1882565A (zh) 2003-11-17 2006-12-20 贝林格尔.英格海姆国际有限公司 哌啶取代的吲哚或其杂环衍生物以及它们作为趋化因子－受体(ccr－3)调节剂的用途
US20050245540A1 (en) * 2003-12-09 2005-11-03 Fujisawa Pharmaceutical Co., Ltd. New methods
ES2431524T3 (es) 2004-04-13 2013-11-26 Incyte Corporation Derivados de piperazinilpiperidina como antagonistas de los receptores de quimiocinas
MXPA06014574A (es) 2004-06-24 2007-03-12 Incyte Corp Piperidinas n-sustituidas y su uso como farmaceuticos.
EP1773773A4 (en) * 2004-06-24 2009-07-29 Incyte Corp AMID COMPOUNDS AND THEIR USE AS MEDICAMENTS
ES2341127T3 (es) * 2005-04-26 2010-06-15 Hypnion, Inc. Compuestos de bencisoxazol-piperazina y procedimiento de uso.
WO2006117314A2 (en) 2005-04-30 2006-11-09 Boehringer Ingelheim International Gmbh Novel piperidin- substituted indoles and their use as ccr-3 modulators
US20060275516A1 (en) * 2005-06-02 2006-12-07 Ram A N S Compositions and methods for the treatment of allergic rhinitis
US20080108586A1 (en) * 2006-09-06 2008-05-08 Incyte Corporation Combination therapy for human immunodeficiency virus infection
EP2079725B1 (en) * 2006-10-27 2011-12-14 Boehringer Ingelheim International GmbH Piperidyl-propane-thiol ccr3 modulators
DK2137162T3 (en) * 2007-03-15 2018-11-26 Novartis Ag Organic compounds and their applications
US20100041663A1 (en) 2008-07-18 2010-02-18 Novartis Ag Organic Compounds as Smo Inhibitors
CN101560179B (zh) * 2009-05-25 2012-04-18 浙江大学 具有h3受体亲和能力的含氮吲哚衍生物和用途
CN101747321B (zh) * 2009-12-22 2013-01-02 浙江大学 吲哚-3-苄胺衍生物及制备方法和用途
EP3040334A1 (en) * 2014-12-29 2016-07-06 Faes Farma, S.A. New benzimidazole derivatives as antihistamine agents
WO2023006893A1 (en) * 2021-07-30 2023-02-02 Confo Therapeutics N.V. Compounds for the treatment of pain, in particular neuropathic pain, and/or other diseases or disorders that are associated with at2r and/or at2r mediated signaling

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4742057A (en) * 1985-12-05 1988-05-03 Fujisawa Pharmaceutical Co., Ltd. Antiallergic thiazole compounds
JPS63301881A (ja) * 1987-06-01 1988-12-08 Fujisawa Pharmaceut Co Ltd インドリルピペリジン誘導体
DK733788A (da) * 1988-01-14 1989-07-15 Fujisawa Pharmaceutical Co Indolylpiperidinderivater og fremgangsmaade til fremstilling deraf
GB8900382D0 (en) * 1989-01-09 1989-03-08 Janssen Pharmaceutica Nv 2-aminopyrimidinone derivatives
NZ249286A (en) * 1992-02-13 1996-02-27 Merrell Dow Pharma Piperidine-4-ylmethyl thiophene and thiazole derivatives and pharmaceutical compositions
IT1271417B (it) * 1993-10-15 1997-05-28 Erregierre Ind Chim Composti ad attivita' antiistaminica procedimento per la loro preperazione e composizioni farmaceutiche che li contengono.
DE19500689A1 (de) 1995-01-12 1996-07-18 Merck Patent Gmbh Indolpiperidin-Derivate
DE19707628A1 (de) 1997-02-26 1998-08-27 Merck Patent Gmbh Oxazolidinone
AR013669A1 (es) * 1997-10-07 2001-01-10 Smithkline Beecham Corp Compuestos y metodos
AR028685A1 (es) * 2000-06-14 2003-05-21 Lundbeck & Co As H Derivados de indol

Also Published As

Publication number Publication date
US20020147344A1 (en) 2002-10-10
RU2246493C2 (ru) 2005-02-20
CA2375985A1 (en) 2000-12-14
MY127033A (en) 2006-11-30
ES2211559T3 (es) 2004-07-16
TWI226889B (en) 2005-01-21
HK1040990A1 (zh) 2002-06-28
HUP0203320A2 (hu) 2003-02-28
RU2002100073A (ru) 2004-01-10
ATE259362T1 (de) 2004-02-15
KR20020020721A (ko) 2002-03-15
DE60008239T2 (de) 2004-11-18
BR0011340A (pt) 2002-03-05
NO20015897D0 (no) 2001-12-03
ZA200109676B (en) 2003-02-24
HUP0203320A3 (en) 2004-01-28
WO2000075130A1 (en) 2000-12-14
US6683096B2 (en) 2004-01-27
MXPA01012425A (es) 2002-06-04
BG106168A (bg) 2002-07-31
ES2165274A1 (es) 2002-03-01
KR100683454B1 (ko) 2007-02-20
EP1183251B1 (en) 2004-02-11
IL146629A0 (en) 2002-07-25
AR029640A1 (es) 2003-07-10
CN1191246C (zh) 2005-03-02
PL353164A1 (en) 2003-10-20
PT1183251E (pt) 2004-05-31
TR200103490T2 (tr) 2002-04-22
AU5527600A (en) 2000-12-28
AU773164B2 (en) 2004-05-20
EE04717B1 (et) 2006-10-16
PE20010208A1 (es) 2001-03-19
ES2165274B1 (es) 2003-04-01
JP2003501424A (ja) 2003-01-14
NO20015897L (no) 2001-12-03
SK17042001A3 (sk) 2002-04-04
EE200100653A (et) 2003-02-17
DE60008239D1 (de) 2004-03-18
CZ20014334A3 (cs) 2002-03-13
CO5180556A1 (es) 2002-07-30
CN1368969A (zh) 2002-09-11
EP1183251A1 (en) 2002-03-06
NZ515649A (en) 2003-08-29
SI1183251T1 (en) 2004-06-30
PL196774B1 (pl) 2008-01-31
UA72517C2 (uk) 2005-03-15

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