DK1140886T3 - Fremgangsmåde til fremstilling af 5-cyanophtalid - Google Patents

Fremgangsmåde til fremstilling af 5-cyanophtalid

Info

Publication number
DK1140886T3
DK1140886T3 DK99960958T DK99960958T DK1140886T3 DK 1140886 T3 DK1140886 T3 DK 1140886T3 DK 99960958 T DK99960958 T DK 99960958T DK 99960958 T DK99960958 T DK 99960958T DK 1140886 T3 DK1140886 T3 DK 1140886T3
Authority
DK
Denmark
Prior art keywords
cyanophthalide
preparation
Prior art date
Application number
DK99960958T
Other languages
Danish (da)
English (en)
Inventor
Hans Petersen
Nielsen Poul Dahlberg
Original Assignee
Lundbeck & Co As H
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lundbeck & Co As H filed Critical Lundbeck & Co As H
Application granted granted Critical
Publication of DK1140886T3 publication Critical patent/DK1140886T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87—Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/88—Benzo [c] furans; Hydrogenated benzo [c] furans with one oxygen atom directly attached in position 1 or 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Furan Compounds (AREA)
DK99960958T 1998-12-23 1999-12-22 Fremgangsmåde til fremstilling af 5-cyanophtalid DK1140886T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DKPA199801718 1998-12-23
PCT/DK1999/000728 WO2000039112A1 (en) 1998-12-23 1999-12-22 Method for the preparation of 5-cyanophthalide

Publications (1)

Publication Number Publication Date
DK1140886T3 true DK1140886T3 (da) 2003-07-28

Family

ID=8107494

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99960958T DK1140886T3 (da) 1998-12-23 1999-12-22 Fremgangsmåde til fremstilling af 5-cyanophtalid

Country Status (31)

Country Link
US (1) US6392060B2 (ru)
EP (1) EP1140886B1 (ru)
JP (1) JP2002533450A (ru)
KR (1) KR100454008B1 (ru)
CN (1) CN1149208C (ru)
AR (1) AR019791A1 (ru)
AT (1) ATE236145T1 (ru)
AU (1) AU764161B2 (ru)
BG (1) BG64986B1 (ru)
BR (1) BR9916955A (ru)
CA (1) CA2356188C (ru)
CZ (1) CZ300408B6 (ru)
DE (1) DE69906580T2 (ru)
DK (1) DK1140886T3 (ru)
EA (1) EA003057B1 (ru)
ES (1) ES2195644T3 (ru)
HK (1) HK1043130B (ru)
HU (1) HUP0104856A3 (ru)
IL (1) IL143422A0 (ru)
IS (1) IS2261B (ru)
IT (1) IT1315269B1 (ru)
NO (1) NO326516B1 (ru)
NZ (1) NZ512073A (ru)
PL (1) PL203275B1 (ru)
PT (1) PT1140886E (ru)
SI (1) SI1140886T1 (ru)
SK (1) SK285530B6 (ru)
TR (1) TR200101796T2 (ru)
UA (1) UA70979C2 (ru)
WO (1) WO2000039112A1 (ru)
ZA (1) ZA200104262B (ru)

Families Citing this family (27)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU746665B2 (en) 1998-10-20 2002-05-02 H. Lundbeck A/S Method for the preparation of citalopram
BR9916955A (pt) 1998-12-23 2001-09-11 Lundbeck & Co As H Método para preparação de 5-cianoftalida
AR022329A1 (es) * 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) * 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
SK287140B6 (sk) 1999-10-25 2010-01-07 H. Lundbeck A/S Spôsob prípravy citalopramu a medziprodukt na jeho výrobu
CH692421A5 (de) 1999-10-25 2002-06-14 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram.
AR026063A1 (es) 1999-11-01 2002-12-26 Lundbeck & Co As H Metodo para la preparacion de 5-carboxiftalida.
PL355532A1 (en) 1999-12-28 2004-05-04 H.Lundbeck A/S Method for the preparation of citalopram
CZ20022627A3 (cs) 1999-12-30 2002-10-16 H. Lundbeck A/S Způsob výroby citalopramu
SK286879B6 (sk) 2000-01-14 2009-07-06 H. Lundbeck A/S Spôsob prípravy 5-kyanoftalidu
NL1017415C1 (nl) 2000-02-24 2001-05-18 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
NL1017417C1 (nl) 2000-03-03 2001-03-16 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
JP2003527385A (ja) 2000-03-13 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット ５−置換された１−（４−フルオロフェニル）−１，３−ジヒドロイソベンゾフランの段階的アルキル化法
NL1017500C1 (nl) 2000-03-13 2001-04-26 Lundbeck & Co As H Werkwijze voor de bereiding van Citalopram.
JP2003527387A (ja) 2000-03-13 2003-09-16 ハー・ルンドベック・アクチエゼルスカベット シタロプラムの製造方法
PT1265882E (pt) 2000-03-14 2004-06-30 Lundbeck & Co As H Metodo para preparacao de citalopram; composto e citalopram
TR200202168T2 (tr) * 2000-03-16 2002-12-23 H. Lundbeck A/S 5-Siyano-1-(4-Florofenil)-1,3-Dihidroizobenzofuranların preparasyon metodu
AR032455A1 (es) 2000-05-12 2003-11-12 Lundbeck & Co As H Metodo para la preparacion de citalopram, un intermediario empleado en el metodo, un metodo para la preparacion del intermediario empleado en el metodo y composicion farmaceutica antidepresiva
FI20011622A (fi) * 2000-08-18 2002-02-19 Lundbeck & Co As H Menetelmä sitalopraamin valmistamiseksi
DK1181713T3 (da) 2000-12-22 2005-01-31 Lundbeck & Co As H Fremgangsmåde til fremstilling af rent citalopram
KR100430746B1 (ko) 2000-12-28 2004-05-10 하. 룬트벡 아크티에 셀스카브 순수한 시탈로프람의 제조방법
EP1321464A1 (en) * 2001-12-21 2003-06-25 ICROM S.p.A. Process for the preparation of 5-cyanophthalide and intermediates useful therein
US7687645B2 (en) 2003-03-21 2010-03-30 H. Lundbeck A/S Intermediates for the preparation of citalopram and escitalopram
US20050154052A1 (en) * 2003-03-24 2005-07-14 Hetero Drugs Limited Novel crystalline forms of (s)-citalopram oxalate
EP1777221A1 (en) 2005-10-14 2007-04-25 Adorkem Technology SpA Process for the preparation of 5-cyanophthalide starting from 5-carboxyphthalide

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1143703A (ru) 1965-03-18
GB1526331A (en) 1976-01-14 1978-09-27 Kefalas As Phthalanes
GB8419963D0 (en) 1984-08-06 1984-09-12 Lundbeck & Co As H Intermediate compound and method
GB8814057D0 (en) 1988-06-14 1988-07-20 Lundbeck & Co As H New enantiomers & their isolation
DK213290D0 (da) 1990-09-06 1990-09-06 Lundbeck & Co As H Treatment of cerebrovascular disorders
DE19626659A1 (de) 1996-07-03 1998-01-08 Basf Ag Verfahren zur Herstellung von Phthaliden
DE19627697A1 (de) 1996-07-10 1998-01-15 Basf Ag Verfahren zur Herstellung von Phthaliden
ZA9711376B (en) 1996-12-20 1998-07-21 Lundbeck & Co As H Indole or dihydroindole derivatives
EA001728B1 (ru) * 1997-07-08 2001-08-27 Х.Лундбекк А/С Способ получения циталопрама
UA62985C2 (en) 1997-11-10 2004-01-15 Lunnbeck As H A method for the preparation of citalopram
SK283907B6 (sk) 1997-11-11 2004-04-06 H. Lundbeck A/S Spôsob výroby citalopramu a medziprodukty
AU746665B2 (en) 1998-10-20 2002-05-02 H. Lundbeck A/S Method for the preparation of citalopram
BR9916955A (pt) 1998-12-23 2001-09-11 Lundbeck & Co As H Método para preparação de 5-cianoftalida
AR022329A1 (es) 1999-01-29 2002-09-04 Lundbeck & Co As H Metodo para la preparacion de 5-cianoftalida
PL198024B1 (pl) 1999-04-14 2008-05-30 Lundbeck & Co As H Sposób wytwarzania citalopramu, związki pośrednie i ich zastosowanie do wytwarzania citalopramu
ITMI991579A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
ITMI991581A1 (it) 1999-06-25 2001-01-15 Lundbeck & Co As H Metodo per la preparazione di citalopram
CH692421A5 (de) 1999-10-25 2002-06-14 Lundbeck & Co As H Verfahren zur Herstellung von Citalopram.
US6310222B1 (en) 1999-11-01 2001-10-30 Sumika Fine Chemicals Co., Ltd. Production method of 5-phthalancarbonitrile compound, intermediate therefor and production method of the intermediate

Also Published As

Publication number Publication date
AU764161B2 (en) 2003-08-14
EA003057B1 (ru) 2002-12-26
PT1140886E (pt) 2003-08-29
EA200100696A1 (ru) 2001-12-24
BG105655A (en) 2002-01-31
ATE236145T1 (de) 2003-04-15
KR100454008B1 (ko) 2004-10-20
UA70979C2 (ru) 2004-11-15
CA2356188A1 (en) 2000-07-06
WO2000039112A1 (en) 2000-07-06
NO326516B1 (no) 2008-12-22
EP1140886A1 (en) 2001-10-10
PL203275B1 (pl) 2009-09-30
KR20010082370A (ko) 2001-08-29
DE69906580T2 (de) 2004-02-12
NO20013150D0 (no) 2001-06-22
SK8962001A3 (en) 2003-03-04
ZA200104262B (en) 2001-12-11
ES2195644T3 (es) 2003-12-01
CA2356188C (en) 2006-05-23
CZ20012335A3 (cs) 2001-12-12
BR9916955A (pt) 2001-09-11
CN1149208C (zh) 2004-05-12
PL348608A1 (en) 2002-06-03
HUP0104856A3 (en) 2003-01-28
HK1043130B (zh) 2005-03-04
CN1331686A (zh) 2002-01-16
CZ300408B6 (cs) 2009-05-13
ITMI992696A0 (it) 1999-12-23
TR200101796T2 (tr) 2001-11-21
HUP0104856A2 (hu) 2002-04-29
DE69906580D1 (de) 2003-05-08
HK1043130A1 (en) 2002-09-06
AU1774200A (en) 2000-07-31
IS5952A (is) 2001-05-22
IS2261B (is) 2007-06-15
US6392060B2 (en) 2002-05-21
ITMI992696A1 (it) 2001-06-23
SI1140886T1 (en) 2003-08-31
BG64986B1 (bg) 2006-11-30
IT1315269B1 (it) 2003-02-03
NO20013150L (no) 2001-08-20
IL143422A0 (en) 2002-04-21
AR019791A1 (es) 2002-03-13
EP1140886B1 (en) 2003-04-02
JP2002533450A (ja) 2002-10-08
NZ512073A (en) 2003-10-31
SK285530B6 (sk) 2007-03-01
US20020019546A1 (en) 2002-02-14

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