DK0974366T3 - Orale, farmaceutiske præparater med nedsat bitterhed ved maskering - Google Patents
Orale, farmaceutiske præparater med nedsat bitterhed ved maskeringInfo
- Publication number
- DK0974366T3 DK0974366T3 DK98911029T DK98911029T DK0974366T3 DK 0974366 T3 DK0974366 T3 DK 0974366T3 DK 98911029 T DK98911029 T DK 98911029T DK 98911029 T DK98911029 T DK 98911029T DK 0974366 T3 DK0974366 T3 DK 0974366T3
- Authority
- DK
- Denmark
- Prior art keywords
- masking
- pharmaceutical preparations
- oral pharmaceutical
- reduced bitterness
- unpleasant
- Prior art date
Links
- 230000000873 masking effect Effects 0.000 title abstract 2
- 235000019658 bitter taste Nutrition 0.000 title 1
- 239000008183 oral pharmaceutical preparation Substances 0.000 title 1
- 239000003814 drug Substances 0.000 abstract 3
- 229940079593 drug Drugs 0.000 abstract 2
- 235000019640 taste Nutrition 0.000 abstract 2
- 125000000129 anionic group Chemical group 0.000 abstract 1
- 229940113118 carrageenan Drugs 0.000 abstract 1
- 235000010418 carrageenan Nutrition 0.000 abstract 1
- 229920001525 carrageenan Polymers 0.000 abstract 1
- 239000000679 carrageenan Substances 0.000 abstract 1
- 230000003247 decreasing effect Effects 0.000 abstract 1
- 239000008187 granular material Substances 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- 229940126701 oral medication Drugs 0.000 abstract 1
- 239000000843 powder Substances 0.000 abstract 1
- 239000000126 substance Substances 0.000 abstract 1
- 235000020357 syrup Nutrition 0.000 abstract 1
- 239000006188 syrup Substances 0.000 abstract 1
- UHVMMEOXYDMDKI-JKYCWFKZSA-L zinc;1-(5-cyanopyridin-2-yl)-3-[(1s,2s)-2-(6-fluoro-2-hydroxy-3-propanoylphenyl)cyclopropyl]urea;diacetate Chemical compound [Zn+2].CC([O-])=O.CC([O-])=O.CCC(=O)C1=CC=C(F)C([C@H]2[C@H](C2)NC(=O)NC=2N=CC(=CC=2)C#N)=C1O UHVMMEOXYDMDKI-JKYCWFKZSA-L 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Inorganic Chemistry (AREA)
- Neurosurgery (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP7856897 | 1997-03-28 | ||
| JP34326597 | 1997-12-12 | ||
| PCT/JP1998/001360 WO1998043675A1 (en) | 1997-03-28 | 1998-03-26 | Oral pharmaceutical preparations decreased in bitterness by masking |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0974366T3 true DK0974366T3 (da) | 2007-01-29 |
Family
ID=26419628
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK98911029T DK0974366T3 (da) | 1997-03-28 | 1998-03-26 | Orale, farmaceutiske præparater med nedsat bitterhed ved maskering |
Country Status (9)
| Country | Link |
|---|---|
| US (1) | US7727552B1 (da) |
| EP (1) | EP0974366B1 (da) |
| JP (1) | JP5053228B2 (da) |
| KR (1) | KR100693266B1 (da) |
| AT (1) | ATE342735T1 (da) |
| DE (1) | DE69836207T2 (da) |
| DK (1) | DK0974366T3 (da) |
| ES (1) | ES2273409T3 (da) |
| WO (1) | WO1998043675A1 (da) |
Families Citing this family (25)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100764520B1 (ko) * | 1998-08-28 | 2007-10-09 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 고미 등을 경감한 의약조성물 |
| KR20000046974A (ko) * | 1998-12-31 | 2000-07-25 | 윤재승 | 아세글루타미드 알루미늄의 경구 투여용 제제 조성물ㅇ |
| US6432448B1 (en) * | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
| US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
| US6932861B2 (en) | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
| TR200300731T2 (tr) | 2000-11-28 | 2004-08-23 | Fmc Corporation | Yenebilir PGA kaplama bileşimi |
| US7125565B2 (en) * | 2000-12-01 | 2006-10-24 | Kyowa Hakko Kogyo Co., Ltd. | Composition improved in the solubility or oral absorbability |
| WO2003097102A1 (fr) * | 2002-05-22 | 2003-11-27 | Shionogi & Co., Ltd. | Preparation pharmaceutique dans laquelle la propriete de dissolution d'un medicament faiblement soluble dans l'eau est amelioree |
| US20050232990A1 (en) * | 2003-12-31 | 2005-10-20 | Garth Boehm | Donepezil formulations |
| CN101951923B (zh) | 2007-12-20 | 2013-10-30 | N.V.努特里奇亚 | 含核苷酸/核苷的液态产品 |
| CN102105154B (zh) * | 2008-07-30 | 2013-03-27 | 三得利控股株式会社 | 含有含硫酸软骨素的水系溶剂提取物以及槲皮素糖苷的口服给药用制剂 |
| US8715715B2 (en) * | 2008-11-03 | 2014-05-06 | Nal Pharmaceuticals Ltd. | Dosage form for insertion into the mouth |
| EP2243473B1 (en) | 2009-04-17 | 2018-08-08 | Hexal AG | Tablets comprising a taste masking agent |
| EP2366378A1 (en) | 2010-03-01 | 2011-09-21 | Dexcel Pharma Technologies Ltd. | Sustained-release donepezil formulations |
| JP5491943B2 (ja) * | 2010-04-28 | 2014-05-14 | ゼリア新薬工業株式会社 | ビタミンb1類含有経口ゼリー剤 |
| SG10201507554RA (en) | 2010-09-13 | 2015-10-29 | Bev Rx Inc | Aqueous drug delivery system comprising off - flavor masking agent |
| EP2468254A1 (en) | 2010-12-15 | 2012-06-27 | Hexal AG | Orally disintegrating tablet having a taste masking effect |
| CA2821919C (en) * | 2010-12-23 | 2015-12-15 | Colgate-Palmolive Company | Fluid oral care composition comprising gellan gum, xanthan gum and a sodium salt |
| JP6506692B2 (ja) * | 2012-10-25 | 2019-04-24 | ネステク ソシエテ アノニム | カプセル化された苦味ペプチド、苦味ペプチドをカプセル化する方法、及びカプセル化された苦味ペプチドを含む栄養組成物 |
| ES2888074T3 (es) | 2013-08-16 | 2021-12-30 | Univ Maastricht | Tratamiento del deterioro cognitivo con inhibidor de PDE4 |
| CN106727272A (zh) * | 2016-12-08 | 2017-05-31 | 星康桥医药科技(南京)有限公司 | 一种漱口制剂及漱口方法 |
| US10849880B2 (en) | 2016-12-28 | 2020-12-01 | Fujifilm Toyama Chemical Co., Ltd. | Pharmaceutical composition |
| KR20200064951A (ko) | 2018-11-29 | 2020-06-08 | 동국제약 주식회사 | 약리학적 활성 성분을 함유한 구강붕해필름 및 그의 제조방법 |
| AU2022215028A1 (en) | 2021-01-28 | 2023-06-29 | Galvita Ag | Solid pharmaceutical compositions and methods of producing the same |
| EP4311543A1 (en) | 2022-07-27 | 2024-01-31 | Galvita AG | Methods for loading template inverted carriers |
Family Cites Families (57)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5176413A (ja) | 1974-12-25 | 1976-07-02 | Toyo Jozo Kk | Hifukuzainoseizoho |
| JPS5476818A (en) * | 1977-11-25 | 1979-06-19 | Egyt Gyogyszervegyeszeti Gyar | Pharmaceutical composition having prolonged effect and production thereof |
| JPS5565741A (en) * | 1978-11-10 | 1980-05-17 | Tokico Ltd | Shock absorber |
| GB2122892B (en) | 1982-07-02 | 1986-01-29 | Squibb & Sons Inc | Nystantin pastille formulation |
| JPS60204712A (ja) | 1984-03-29 | 1985-10-16 | Ss Pharmaceut Co Ltd | 塩酸メクリジンの安定化液状組成物 |
| JPS61130239A (ja) | 1984-11-30 | 1986-06-18 | Dai Ichi Seiyaku Co Ltd | 複合体 |
| US5286489A (en) * | 1985-08-26 | 1994-02-15 | The Procter & Gamble Company | Taste masking compositions |
| JPS63309150A (ja) * | 1987-06-11 | 1988-12-16 | San Ei Chem Ind Ltd | 即席ゲル状物の製造法 |
| JPH0717498B2 (ja) | 1989-05-31 | 1995-03-01 | 興和株式会社 | 鎮咳去痰ソフトカプセル剤 |
| US5084278A (en) | 1989-06-02 | 1992-01-28 | Nortec Development Associates, Inc. | Taste-masked pharmaceutical compositions |
| US5013557A (en) * | 1989-10-03 | 1991-05-07 | Warner-Lambert Company | Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same |
| US5077053A (en) | 1990-02-12 | 1991-12-31 | Warner-Lambert Company | Zein as a moisture barrier for sugarless edible compositions and method for preparing same |
| JPH03287535A (ja) | 1990-03-31 | 1991-12-18 | Bairon Boeki Kk | プラノプロフェン水溶液 |
| JPH0418015A (ja) | 1990-05-10 | 1992-01-22 | Fujikawa Kk | 安定なフマル酸クレマスチン水溶液 |
| JP2508547B2 (ja) | 1991-01-08 | 1996-06-19 | 株式会社紀文食品 | 苦味低減方法及び苦味低減化組成物 |
| JP3073544B2 (ja) * | 1991-02-18 | 2000-08-07 | 三栄源エフ・エフ・アイ株式会社 | 塩化カリウムの脱苦味方法 |
| JPH04282312A (ja) | 1991-03-08 | 1992-10-07 | Eisai Co Ltd | コ−ティング層を有する粒状物 |
| JP2508555B2 (ja) | 1991-05-24 | 1996-06-19 | 株式会社紀文食品 | 苦味低減方法 |
| CA2068402C (en) | 1991-06-14 | 1998-09-22 | Michael R. Hoy | Taste mask coatings for preparation of chewable pharmaceutical tablets |
| DE4122217C2 (de) | 1991-07-04 | 1997-02-13 | Merz & Co Gmbh & Co | Verfahren zur Herstellung mechanisch stabiler, gut zerfallender Komprimate aus kleinen wirkstoffhaltigen Formkörpern |
| JPH05163154A (ja) | 1991-12-13 | 1993-06-29 | Kanebo Ltd | 経口液剤 |
| DE69227467T2 (de) | 1991-12-24 | 1999-04-22 | Yamanouchi Pharmaceutical Co., Ltd., Tokio/Tokyo | Intrabukkal desintegrierende zubereitung und ihre herstellung |
| EP0553777B1 (en) | 1992-01-29 | 2002-04-24 | Takeda Chemical Industries, Ltd. | Fast dissolving tablet and its production |
| JPH06218028A (ja) | 1992-10-02 | 1994-08-09 | Eisai Co Ltd | 湿製錠の成型方法とその装置及び湿製錠 |
| WO1994013257A1 (en) | 1992-12-16 | 1994-06-23 | Creative Products Resource Associates, Ltd. | Occlusive/semi-occlusive lotion for treatment of a skin disease or disorder |
| DE69419281T2 (de) * | 1993-04-28 | 2000-03-23 | Takeda Chemical Industries, Ltd. | Geschmacksmaskierte feste Zubereitung und Verfahren zur Herstellung |
| CN1070896C (zh) | 1993-10-01 | 2001-09-12 | 花王株式会社 | 屏蔽紫外线复合微粒及其生产方法和化妆品 |
| US5576014A (en) | 1994-01-31 | 1996-11-19 | Yamanouchi Pharmaceutical Co., Ltd | Intrabuccally dissolving compressed moldings and production process thereof |
| JPH07267850A (ja) | 1994-03-28 | 1995-10-17 | Eisai Co Ltd | 不快味を防止した医薬組成物及びその製造方法 |
| US5672364A (en) | 1994-07-07 | 1997-09-30 | Sankyo Seisakusho Co. & Eisai Co., Ltd. | Apparatus for manufacturing tablets |
| JP3187657B2 (ja) | 1994-07-08 | 2001-07-11 | 株式会社三共製作所 | 錠剤製造方法およびその装置 |
| DE4432757A1 (de) | 1994-09-14 | 1996-03-21 | Boehringer Mannheim Gmbh | Pharmazeutische Zubereitung enthaltend Metformin und Verfahren zu deren Herstellung |
| US5656284A (en) * | 1995-04-24 | 1997-08-12 | Balkin; Michael S. | Oral transmucosal delivery tablet and method of making it |
| JPH08333245A (ja) | 1995-06-07 | 1996-12-17 | Taisho Pharmaceut Co Ltd | イブプロフェン懸濁液剤 |
| SK74396A3 (en) | 1995-06-13 | 1997-04-09 | American Home Prod | Organoleptically acceptable oral pharmaceutical compositions |
| TW442287B (en) | 1995-06-13 | 2001-06-23 | American Home Produits Corp | Organoleptically acceptable oral pharmaceutical composition comprising the S(+)1,8-diethyl-1-1,3,4,9-tetrahydropyrano[3,4-b] indole-1-acetic acid (Etodolac) |
| JPH0948726A (ja) | 1995-08-07 | 1997-02-18 | Tanabe Seiyaku Co Ltd | 口腔内速崩壊性製剤およびその製法 |
| JPH09143100A (ja) | 1995-11-20 | 1997-06-03 | Sumitomo Pharmaceut Co Ltd | 服用感の改善された固形製剤 |
| US6214386B1 (en) | 1995-11-22 | 2001-04-10 | Recordati, S.A. | Prompt-release oral pharmaceutical compositions for extemporaneous suspensions |
| US5612026A (en) * | 1996-01-25 | 1997-03-18 | The Procter & Gamble Company | Cholesterol lowering drink mix compositons |
| JPH103629A (ja) | 1996-06-14 | 1998-01-06 | Asahi Komagu Kk | 薄膜磁気ヘッドスライダーの製造方法 |
| ATE291930T1 (de) | 1996-07-12 | 2005-04-15 | Daiichi Seiyaku Co | Schnell zerfallende, druckgeformte materialien sowie prozess zu deren herstellung |
| US5763449A (en) | 1996-08-07 | 1998-06-09 | Ascent Pediatrics, Inc. | Pleasant-tasting aqueous liquid composition of a bitter-tasting drug |
| JPH10114683A (ja) | 1996-10-11 | 1998-05-06 | Kobayashi Seiyaku Kogyo Kk | 非ステロイド性解熱鎮痛消炎剤を含む固形製剤及びその製造方法 |
| US5962535A (en) | 1997-01-17 | 1999-10-05 | Takeda Chemical Industries, Ltd. | Composition for alzheimer's disease |
| JP4234666B2 (ja) | 1997-03-28 | 2009-03-04 | エーザイ・アール・アンド・ディー・マネジメント株式会社 | 苦味等を隠蔽した経口薬剤 |
| JP3770518B2 (ja) | 1997-03-28 | 2006-04-26 | エーザイ株式会社 | 苦味等を隠蔽した経口薬剤 |
| TW580397B (en) | 1997-05-27 | 2004-03-21 | Takeda Chemical Industries Ltd | Solid preparation |
| JP3797764B2 (ja) | 1997-10-01 | 2006-07-19 | エーザイ株式会社 | 光安定化組成物 |
| TW527195B (en) | 1997-10-09 | 2003-04-11 | Ssp Co Ltd | Fast-soluble solid pharmaceutical combinations |
| JPH11199517A (ja) | 1997-10-31 | 1999-07-27 | Meiji Seika Kaisha Ltd | 口腔内速崩壊性錠剤 |
| US6368625B1 (en) | 1998-08-12 | 2002-04-09 | Cima Labs Inc. | Orally disintegrable tablet forming a viscous slurry |
| KR100764520B1 (ko) | 1998-08-28 | 2007-10-09 | 에자이 알앤드디 매니지먼트 가부시키가이샤 | 고미 등을 경감한 의약조성물 |
| US6743443B1 (en) | 1998-10-05 | 2004-06-01 | Eisai Co., Ltd. | Tablets immediately disintegrating in the oral cavity |
| WO2000025754A2 (en) | 1998-11-04 | 2000-05-11 | Mcneil-Ppc, Inc. | Solid oral dosage forms containing alginic acid and famotidine |
| US6656492B2 (en) | 2000-06-30 | 2003-12-02 | Yamanouchi Pharmaceutical Co., Ltd. | Quick disintegrating tablet in buccal cavity and manufacturing method thereof |
| ITMI20020686A1 (it) | 2002-04-03 | 2003-10-03 | Sitma Spa | Dispositivo di stiro di una pellicola in una macchina confezionatriceautomatica di prodotti |
-
1998
- 1998-03-26 DK DK98911029T patent/DK0974366T3/da active
- 1998-03-26 ES ES98911029T patent/ES2273409T3/es not_active Expired - Lifetime
- 1998-03-26 KR KR1019997008568A patent/KR100693266B1/ko not_active Expired - Lifetime
- 1998-03-26 EP EP98911029A patent/EP0974366B1/en not_active Expired - Lifetime
- 1998-03-26 AT AT98911029T patent/ATE342735T1/de active
- 1998-03-26 WO PCT/JP1998/001360 patent/WO1998043675A1/ja not_active Ceased
- 1998-03-26 DE DE69836207T patent/DE69836207T2/de not_active Expired - Lifetime
- 1998-03-26 US US09/380,310 patent/US7727552B1/en not_active Expired - Fee Related
-
2008
- 2008-10-20 JP JP2008270138A patent/JP5053228B2/ja not_active Expired - Lifetime
Also Published As
| Publication number | Publication date |
|---|---|
| EP0974366A4 (en) | 2003-03-26 |
| US7727552B1 (en) | 2010-06-01 |
| DE69836207D1 (de) | 2006-11-30 |
| ES2273409T3 (es) | 2007-05-01 |
| ATE342735T1 (de) | 2006-11-15 |
| DE69836207T2 (de) | 2007-08-30 |
| EP0974366B1 (en) | 2006-10-18 |
| JP5053228B2 (ja) | 2012-10-17 |
| JP2009051855A (ja) | 2009-03-12 |
| EP0974366A1 (en) | 2000-01-26 |
| KR100693266B1 (ko) | 2007-03-27 |
| WO1998043675A1 (en) | 1998-10-08 |
| KR20010005510A (ko) | 2001-01-15 |
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