ATE193533T1 - Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen - Google Patents
Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungenInfo
- Publication number
- ATE193533T1 ATE193533T1 AT96913578T AT96913578T ATE193533T1 AT E193533 T1 ATE193533 T1 AT E193533T1 AT 96913578 T AT96913578 T AT 96913578T AT 96913578 T AT96913578 T AT 96913578T AT E193533 T1 ATE193533 T1 AT E193533T1
- Authority
- AT
- Austria
- Prior art keywords
- taxal
- derivatives
- production
- pharmaceutical compositions
- compositions containing
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
- C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
- C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
- C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Epoxy Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| FR9504559A FR2732968B1 (fr) | 1995-04-14 | 1995-04-14 | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
| PCT/FR1996/000559 WO1996032387A1 (fr) | 1995-04-14 | 1996-04-12 | Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ATE193533T1 true ATE193533T1 (de) | 2000-06-15 |
Family
ID=9478163
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| AT96913578T ATE193533T1 (de) | 1995-04-14 | 1996-04-12 | Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5906990A (de) |
| EP (1) | EP0820448B1 (de) |
| JP (1) | JP4308905B2 (de) |
| AR (1) | AR002041A1 (de) |
| AT (1) | ATE193533T1 (de) |
| AU (1) | AU5652296A (de) |
| DE (1) | DE69608680T2 (de) |
| DK (1) | DK0820448T3 (de) |
| ES (1) | ES2148758T3 (de) |
| FR (1) | FR2732968B1 (de) |
| GR (1) | GR3033591T3 (de) |
| IL (1) | IL117878A (de) |
| PT (1) | PT820448E (de) |
| TW (1) | TW349095B (de) |
| WO (1) | WO1996032387A1 (de) |
| ZA (1) | ZA962900B (de) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0871620A4 (de) | 1995-09-11 | 1999-10-27 | Enzymed Inc | Biokatalytische methoden zur sythese und zur identifikation von biologisch aktiven verbindungen |
| US6156789A (en) * | 1998-03-17 | 2000-12-05 | Rhone-Poulenc Rorer S.A. | Method for treating abnormal cell proliferation in the brain |
| EP0982028A1 (de) * | 1998-08-20 | 2000-03-01 | Aventis Pharma S.A. | Neue Verwendung von Taxoidverbindungen |
| EE200100082A (et) * | 1998-08-20 | 2002-06-17 | Aventis Pharma S.A. | Taksoidi derivaatide kasutamine ravimi valmistamiseks, mis on ette nähtud rakkude ebaloomuliku proliferatsiooni raviks laiaspektrilise ravimresistentsusega P-glükoproteiini ekspresseerivates rakuliinides |
| EP1176957A1 (de) * | 1999-05-03 | 2002-02-06 | Aventis Pharma S.A. | Verfahren zur behandlung von abnormaler zellproliferation des gehirns |
| GEP20043239B (en) | 2000-02-02 | 2004-05-25 | Florida State Univ Research Foundation Us | C10 Carbonate Substituted Taxanes as Antitumor Agents |
| US6649632B2 (en) | 2000-02-02 | 2003-11-18 | Fsu Research Foundation, Inc. | C10 ester substituted taxanes |
| US6596737B2 (en) * | 2000-02-02 | 2003-07-22 | Fsu Research Foundation, Inc. | C10 carbamoyloxy substituted taxanes |
| WO2002066448A1 (en) * | 2001-02-20 | 2002-08-29 | Dabur India Limited | Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid |
| US6956124B2 (en) | 2003-04-14 | 2005-10-18 | Aventis Pharma S.A. | Process for the preparation of 4,10β-diacetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene |
| FR2853651B1 (fr) * | 2003-04-14 | 2005-05-20 | Aventis Pharma Sa | Procede de preparation du 4,10 beta-diacetoxy-2 alpha- benzoyloxy-5 beta, 20-epoxy-1, 13 alpha-dihydroxy-9-oxo-19- norcyclopropa[g]tax-11-ene |
| US20080107721A1 (en) * | 2003-05-20 | 2008-05-08 | Jonathan Lewis | Combination Chemotherapy Comprising A Liposomal Platinum Complex |
| US7064980B2 (en) * | 2003-09-17 | 2006-06-20 | Sandisk Corporation | Non-volatile memory and method with bit line coupled compensation |
| HN2005000054A (es) * | 2004-02-13 | 2009-02-18 | Florida State University Foundation Inc | Taxanos sustituidos con esteres de ciclopentilo en c10 |
| MX2007009748A (es) * | 2005-02-14 | 2007-09-26 | Univ Florida State Res Found | Composiciones de taxano sustituidas con esteres ciclopropilicos en c10. |
| US20090076127A1 (en) * | 2007-09-19 | 2009-03-19 | Protia, Llc | Deuterium-enriched larotaxel |
| US8242166B2 (en) * | 2008-03-31 | 2012-08-14 | Florida State University Research Foundation, Inc. | C(10) ethyl ester and C(10) cyclopropyl ester substituted taxanes |
| EP2177630A1 (de) * | 2008-10-02 | 2010-04-21 | Institut Gustave Roussy | Verfahren für die Prognose oder Überwachung, ob ein Patient mit Krebsleiden auf eine Behandlung mit einem Molekül aus der Taxoid-Familie anspricht |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5294637A (en) * | 1992-07-01 | 1994-03-15 | Bristol-Myers Squibb Company | Fluoro taxols |
| US5254580A (en) * | 1993-01-19 | 1993-10-19 | Bristol-Myers Squibb Company | 7,8-cyclopropataxanes |
| FR2698871B1 (fr) * | 1992-12-09 | 1995-02-24 | Rhone Poulenc Rorer Sa | Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2710642B1 (fr) * | 1993-09-29 | 1995-11-17 | Rhone Poulenc Rorer Sa | Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent. |
| US5395850A (en) * | 1994-03-10 | 1995-03-07 | Bristol-Myers Squibb Company | 6,7-epoxy paclitaxels |
| FR2718135B1 (fr) * | 1994-04-05 | 1996-04-26 | Rhone Poulenc Rorer Sa | Procédé de préparation d'hydroxy-7 taxanes. |
-
1995
- 1995-04-14 FR FR9504559A patent/FR2732968B1/fr not_active Expired - Fee Related
-
1996
- 1996-04-10 TW TW085104260A patent/TW349095B/zh active
- 1996-04-11 ZA ZA962900A patent/ZA962900B/xx unknown
- 1996-04-11 IL IL11787896A patent/IL117878A/xx not_active IP Right Cessation
- 1996-04-12 ES ES96913578T patent/ES2148758T3/es not_active Expired - Lifetime
- 1996-04-12 WO PCT/FR1996/000559 patent/WO1996032387A1/fr active IP Right Grant
- 1996-04-12 PT PT96913578T patent/PT820448E/pt unknown
- 1996-04-12 AR ARP960102178A patent/AR002041A1/es unknown
- 1996-04-12 EP EP96913578A patent/EP0820448B1/de not_active Expired - Lifetime
- 1996-04-12 DK DK96913578T patent/DK0820448T3/da active
- 1996-04-12 US US08/930,814 patent/US5906990A/en not_active Expired - Lifetime
- 1996-04-12 DE DE69608680T patent/DE69608680T2/de not_active Expired - Lifetime
- 1996-04-12 AU AU56522/96A patent/AU5652296A/en not_active Abandoned
- 1996-04-12 JP JP53077796A patent/JP4308905B2/ja not_active Expired - Fee Related
- 1996-04-12 AT AT96913578T patent/ATE193533T1/de active
-
2000
- 2000-06-01 GR GR20000400102T patent/GR3033591T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| DE69608680T2 (de) | 2000-10-19 |
| FR2732968A1 (fr) | 1996-10-18 |
| AR002041A1 (es) | 1998-01-07 |
| EP0820448B1 (de) | 2000-05-31 |
| AU5652296A (en) | 1996-10-30 |
| FR2732968B1 (fr) | 1997-05-16 |
| TW349095B (en) | 1999-01-01 |
| DE69608680D1 (de) | 2000-07-06 |
| JPH11503443A (ja) | 1999-03-26 |
| ES2148758T3 (es) | 2000-10-16 |
| WO1996032387A1 (fr) | 1996-10-17 |
| JP4308905B2 (ja) | 2009-08-05 |
| EP0820448A1 (de) | 1998-01-28 |
| US5906990A (en) | 1999-05-25 |
| IL117878A0 (en) | 1996-08-04 |
| ZA962900B (en) | 1996-07-30 |
| PT820448E (pt) | 2000-09-29 |
| DK0820448T3 (da) | 2000-08-21 |
| GR3033591T3 (en) | 2000-09-29 |
| IL117878A (en) | 2001-03-19 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| UEP | Publication of translation of european patent specification |