ATE233752T1 - Liponsaürederivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen - Google Patents
Liponsaürederivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungenInfo
- Publication number
- ATE233752T1 ATE233752T1 AT00918930T AT00918930T ATE233752T1 AT E233752 T1 ATE233752 T1 AT E233752T1 AT 00918930 T AT00918930 T AT 00918930T AT 00918930 T AT00918930 T AT 00918930T AT E233752 T1 ATE233752 T1 AT E233752T1
- Authority
- AT
- Austria
- Prior art keywords
- production
- pharmaceutical compositions
- compositions containing
- acid derivatives
- liponic acid
- Prior art date
Links
- AGBQKNBQESQNJD-UHFFFAOYSA-N lipoic acid Chemical class OC(=O)CCCCC1CCSS1 AGBQKNBQESQNJD-UHFFFAOYSA-N 0.000 title 1
- 239000008194 pharmaceutical composition Substances 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/08—Drugs for disorders of the alimentary tract or the digestive system for nausea, cinetosis or vertigo; Antiemetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P15/00—Drugs for genital or sexual disorders; Contraceptives
- A61P15/10—Drugs for genital or sexual disorders; Contraceptives for impotence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/04—Centrally acting analgesics, e.g. opioids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/14—Drugs for disorders of the nervous system for treating abnormal movements, e.g. chorea, dyskinesia
- A61P25/16—Anti-Parkinson drugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/32—Alcohol-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
- A61P25/36—Opioid-abuse
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P39/00—General protective or antinoxious agents
- A61P39/06—Free radical scavengers or antioxidants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
- C07C323/50—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton
- C07C323/51—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton
- C07C323/60—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups containing thio groups and carboxyl groups bound to the same carbon skeleton having the sulfur atoms of the thio groups bound to acyclic carbon atoms of the carbon skeleton with the carbon atom of at least one of the carboxyl groups bound to nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D339/00—Heterocyclic compounds containing rings having two sulfur atoms as the only ring hetero atoms
- C07D339/02—Five-membered rings
- C07D339/04—Five-membered rings having the hetero atoms in positions 1 and 2, e.g. lipoic acid
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Neurosurgery (AREA)
- Psychiatry (AREA)
- Immunology (AREA)
- Addiction (AREA)
- Pain & Pain Management (AREA)
- Endocrinology (AREA)
- Reproductive Health (AREA)
- Oncology (AREA)
- Toxicology (AREA)
- Heart & Thoracic Surgery (AREA)
- Hospice & Palliative Care (AREA)
- Communicable Diseases (AREA)
- Cardiology (AREA)
- Vascular Medicine (AREA)
- Psychology (AREA)
- Transplantation (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Biochemistry (AREA)
- Otolaryngology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Urology & Nephrology (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
FR9904132A FR2791677B1 (fr) | 1999-04-02 | 1999-04-02 | Nouveaux derives de l'acide lipoique, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
FR0002315A FR2805537A1 (fr) | 2000-02-24 | 2000-02-24 | Nouveaux derives de l'acide lipoique, leur preparation, leur application a titre de medicaments et les compositions pharmaceutiques les contenant |
PCT/FR2000/000814 WO2000059899A1 (fr) | 1999-04-02 | 2000-03-31 | Nouveaux derives de l'acide lipoïque et les compositions pharmaceutiques les contenant |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE233752T1 true ATE233752T1 (de) | 2003-03-15 |
Family
ID=26212205
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT00918930T ATE233752T1 (de) | 1999-04-02 | 2000-03-31 | Liponsaürederivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen |
Country Status (20)
Country | Link |
---|---|
US (2) | US6605637B1 (de) |
EP (1) | EP1169316B9 (de) |
JP (1) | JP2003505341A (de) |
KR (1) | KR100758763B1 (de) |
CN (1) | CN1173969C (de) |
AR (1) | AR042572A1 (de) |
AT (1) | ATE233752T1 (de) |
AU (1) | AU763572B2 (de) |
CA (1) | CA2369071A1 (de) |
DE (1) | DE60001546T9 (de) |
DK (1) | DK1169316T3 (de) |
ES (1) | ES2193949T3 (de) |
HK (1) | HK1046134B (de) |
HU (1) | HUP0200863A3 (de) |
MY (1) | MY119231A (de) |
NZ (1) | NZ514888A (de) |
PL (1) | PL350994A1 (de) |
PT (1) | PT1169316E (de) |
TW (1) | TWI269794B (de) |
WO (1) | WO2000059899A1 (de) |
Families Citing this family (37)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE19941217A1 (de) * | 1999-08-30 | 2001-03-15 | Asta Medica Ag | Behandlung der Migräne durch Verabreichung von alpha-Liponsäure oder Derivaten derselben |
EP1265891B1 (de) * | 2000-03-16 | 2004-12-29 | Societe De Conseils De Recherches Et D'applications Scientifiques (S.C.R.A.S.) | Heterozyclische oder benzol derivate von liponsäure, deren herstellung und deren verwendung als heilmittel |
IT1319196B1 (it) * | 2000-10-10 | 2003-09-26 | Laboratorio Chimico Int Spa | Sintesi dell'acido r(+)alfa-lipoico. |
EP1339705B1 (de) | 2000-11-30 | 2006-06-07 | Basf Aktiengesellschaft | Verfahren zur herstellung von liponsäure und dihydroliponsaüre |
DE10137381A1 (de) * | 2001-07-31 | 2003-02-13 | Viatris Gmbh | Neue Modifikationen des Trometamolsalzes der R-Thioctsäure sowie Verfahren zu ihrer Herstellung |
CA2461934A1 (en) * | 2001-09-28 | 2003-04-03 | Meagan Medical, Inc. | Method and apparatus for controlling percutaneous electrical signals |
JP2006505290A (ja) * | 2002-11-10 | 2006-02-16 | インスティテュート オブ セル バイオフィジクス ロシアン アカデミー オブ サイエンシーズ | 抗酸化医薬化合物、ポリペプチドの産生方法、治療方法 |
US7202270B2 (en) * | 2003-06-20 | 2007-04-10 | Sami Labs Limited | Convenient stable non-hygroscopic crystalline solid forms of racemic and chiral LA-plus salts: process for their manufacture and uses |
US8916546B2 (en) | 2003-08-29 | 2014-12-23 | Therapeutic Research Llc | Materials and methods for treatment and diagnosis of disorders associated with oxidative stress |
US20070299093A1 (en) * | 2005-01-27 | 2007-12-27 | Alma Mater Studiorum-Universitá Di Bologna | Organic Compounds Useful for the Treatment of Alzheimer's Disease, Their Use and Method of Preparation |
EA200701584A1 (ru) | 2005-01-27 | 2008-02-28 | Альма Матер Студиорум - Университа' Ди Болонья | Органические соединения, применяемые для лечения болезни альцгеймера, их применение и способ получения |
ATE418976T1 (de) | 2005-08-04 | 2009-01-15 | Extarma Ag | Flüssige zusammensetzung enthaltend arginine und alpha-liponsäure zur verbesserung der sexuellen funktion |
FR2908769B1 (fr) * | 2006-11-17 | 2008-12-26 | Oreal | Nouveaux composes derives dithiolanes silicies et leur utilisation |
JP2010520333A (ja) * | 2007-03-01 | 2010-06-10 | セダーズ−シナイ メディカル センター | 〔1,2〕−ジチオラン部分を含有する抗酸化剤重合体およびその使用 |
KR101644192B1 (ko) | 2007-04-18 | 2016-07-29 | 코너스톤 파마슈티칼스, 인크. | 리포산 유도체 |
MX2009013683A (es) | 2007-06-13 | 2010-04-07 | Jay Pravda | Materiales y metodos para el tratamiento y diagnostico de trastornos asociados con estres oxidativo. |
DE102007038849A1 (de) | 2007-08-16 | 2009-02-19 | Adscil Gmbh | Verwendung von R(+)-alpha-Liponsäure zur Behandlung der kryptogenen Neuropathie |
US9028874B2 (en) * | 2008-01-03 | 2015-05-12 | Cedars-Sinai Medical Center | Antioxidant nanosphere comprising [1,2]-dithiolane moieties |
CN102056605A (zh) * | 2008-04-04 | 2011-05-11 | 罗伯特·绍尔 | 药物组合物 |
US8603531B2 (en) | 2008-06-02 | 2013-12-10 | Cedars-Sinai Medical Center | Nanometer-sized prodrugs of NSAIDs |
FR2937035B1 (fr) * | 2008-10-10 | 2010-12-31 | Oreal | Composes dithiolanes ; compositions les contenant ; utilisations pour la photoprotection de la peau |
JP5795961B2 (ja) | 2008-10-21 | 2015-10-14 | ザ ジェネラル ホスピタル コーポレイション | 細胞移植 |
ES2529060T3 (es) | 2008-11-24 | 2015-02-16 | Cedars-Sinai Medical Center | Derivados antioxidantes de la camptotecina y nanoesferas antineoplásicas antioxidantes de los mismos |
WO2010096677A2 (en) * | 2009-02-17 | 2010-08-26 | Invasc Therapeutics, Inc. | Dihydrolipoic acid derivatives comprising nitric oxide and therapeutic uses thereof |
US8632512B2 (en) | 2010-04-09 | 2014-01-21 | Kci Licensing, Inc. | Apparatuses, methods, and compositions for the treatment and prophylaxis of chronic wounds |
US10184110B2 (en) | 2010-08-06 | 2019-01-22 | The General Hospital Corporation | System and apparatus for cell treatment |
US8529873B2 (en) | 2011-08-24 | 2013-09-10 | Los Alamos National Security, Llc | SE-72/AS-72 generator system based on Se extraction/ As reextraction |
US8809308B2 (en) | 2012-11-09 | 2014-08-19 | Scidose, Llc | Enema composition for treatment of ulcerative colitis having long term stability |
WO2015195071A1 (en) | 2014-06-19 | 2015-12-23 | Robert Shorr | Pharmaceutical compounds |
AU2014398232B2 (en) | 2014-06-19 | 2019-11-28 | Rafael Pharmaceuticals, Inc. | Pharmaceutical compounds |
CN105949180B (zh) * | 2016-05-10 | 2018-07-10 | 中山大学 | 治疗中枢神经系统退行性疾病的化合物及其应用 |
CN106279136B (zh) * | 2016-08-15 | 2019-06-21 | 中山大学 | 治疗中枢神经系统退行性疾病或脑肿瘤的化合物及其应用 |
CN106957298B (zh) * | 2017-04-18 | 2019-07-16 | 湖南中医药大学 | 一种硫辛酸苯酚酯衍生物及其制备方法和应用 |
CN107382987A (zh) * | 2017-07-19 | 2017-11-24 | 佛山市第五人民医院 | 一种具有预防和治疗创伤性脑损伤活性的化合物及其制备方法和用途 |
CN111683976B (zh) | 2018-02-05 | 2022-11-18 | 生物辐射实验室股份有限公司 | 具有阴离子交换-疏水混合模式配体的色谱树脂 |
CN112999220B (zh) * | 2021-04-07 | 2022-12-13 | 中国人民解放军南部战区总医院 | α-硫辛酸在作为和/或制备金属β-内酰胺酶抑制剂中的应用 |
CN115778930B (zh) * | 2022-12-08 | 2024-02-27 | 陕西中医药大学 | 一种具有血管舒张活性的二硫缩醛类化合物在制备具有血管舒张活性药物方面的应用 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1205972B (de) | 1963-08-20 | 1965-12-02 | Merck Ag E | Verfahren zur Herstellung eines Liponsaeure-derivates |
US4938636A (en) | 1988-11-14 | 1990-07-03 | Aidlin Automation Corp. | Method and apparatus for feeding container bodies |
JPH06250330A (ja) * | 1993-03-01 | 1994-09-09 | Konica Corp | 写真フィルムの加工方法 |
CZ96798A3 (cs) * | 1997-04-02 | 1998-10-14 | Sankyo Company Limited | Deriváty dithiolanu, jejich příprava a jejich terapeutické účinky |
WO2000006550A1 (fr) * | 1998-07-31 | 2000-02-10 | Nippon Soda Co., Ltd. | Composes phenylazole, procede de production desdits composes et medicaments pour le traitement de l'hyperlipidemie |
BR9914789A (pt) * | 1998-10-26 | 2001-10-02 | Univ New York State Res Found | Derivados de ácido lipóico e seus usos no tratamento de doença |
US6369098B1 (en) * | 1999-10-05 | 2002-04-09 | Bethesda Pharmaceuticals, Inc. | Dithiolane derivatives |
US6492405B2 (en) * | 1999-12-30 | 2002-12-10 | Yissum Research Development Company Of The Hebrew University Of Jerusalem | Nitric oxide donors and pharmaceutical compositions containing them |
US6387945B2 (en) * | 2000-04-11 | 2002-05-14 | The Regents Of The University Of California | Lipoic acid analogs |
-
2000
- 2000-03-30 AR ARP000101441A patent/AR042572A1/es active IP Right Grant
- 2000-03-31 EP EP00918930A patent/EP1169316B9/de not_active Expired - Lifetime
- 2000-03-31 US US09/937,823 patent/US6605637B1/en not_active Expired - Fee Related
- 2000-03-31 JP JP2000609410A patent/JP2003505341A/ja active Pending
- 2000-03-31 PL PL00350994A patent/PL350994A1/xx unknown
- 2000-03-31 WO PCT/FR2000/000814 patent/WO2000059899A1/fr active IP Right Grant
- 2000-03-31 ES ES00918930T patent/ES2193949T3/es not_active Expired - Lifetime
- 2000-03-31 CA CA002369071A patent/CA2369071A1/fr not_active Abandoned
- 2000-03-31 AT AT00918930T patent/ATE233752T1/de not_active IP Right Cessation
- 2000-03-31 AU AU39709/00A patent/AU763572B2/en not_active Ceased
- 2000-03-31 DK DK00918930T patent/DK1169316T3/da active
- 2000-03-31 DE DE60001546T patent/DE60001546T9/de not_active Expired - Fee Related
- 2000-03-31 CN CNB008069778A patent/CN1173969C/zh not_active Expired - Fee Related
- 2000-03-31 MY MYPI20001317A patent/MY119231A/en unknown
- 2000-03-31 PT PT00918930T patent/PT1169316E/pt unknown
- 2000-03-31 NZ NZ514888A patent/NZ514888A/xx not_active IP Right Cessation
- 2000-03-31 KR KR1020017012615A patent/KR100758763B1/ko not_active IP Right Cessation
- 2000-03-31 HU HU0200863A patent/HUP0200863A3/hu unknown
- 2000-04-01 TW TW089106172A patent/TWI269794B/zh active
-
2002
- 2002-10-10 HK HK02107396.3A patent/HK1046134B/zh not_active IP Right Cessation
-
2003
- 2003-04-21 US US10/419,671 patent/US6887891B2/en not_active Expired - Fee Related
Also Published As
Publication number | Publication date |
---|---|
CN1349523A (zh) | 2002-05-15 |
MY119231A (en) | 2005-04-30 |
KR20010108444A (ko) | 2001-12-07 |
AR042572A1 (es) | 2005-06-29 |
ES2193949T3 (es) | 2003-11-16 |
EP1169316A1 (de) | 2002-01-09 |
AU763572B2 (en) | 2003-07-24 |
AU3970900A (en) | 2000-10-23 |
TWI269794B (en) | 2007-01-01 |
KR100758763B1 (ko) | 2007-09-14 |
NZ514888A (en) | 2002-12-20 |
DK1169316T3 (da) | 2003-06-30 |
WO2000059899A8 (fr) | 2001-03-22 |
US6887891B2 (en) | 2005-05-03 |
PT1169316E (pt) | 2003-07-31 |
CA2369071A1 (fr) | 2000-10-12 |
DE60001546T9 (de) | 2004-11-04 |
PL350994A1 (en) | 2003-02-24 |
HUP0200863A3 (en) | 2005-02-28 |
CN1173969C (zh) | 2004-11-03 |
WO2000059899A1 (fr) | 2000-10-12 |
US6605637B1 (en) | 2003-08-12 |
HK1046134B (zh) | 2005-04-22 |
EP1169316B9 (de) | 2003-10-29 |
EP1169316B1 (de) | 2003-03-05 |
US20040019084A1 (en) | 2004-01-29 |
DE60001546D1 (de) | 2003-04-10 |
DE60001546T2 (de) | 2004-02-19 |
HUP0200863A2 (en) | 2002-08-28 |
JP2003505341A (ja) | 2003-02-12 |
HK1046134A1 (en) | 2002-12-27 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DE60001546D1 (de) | Liponsaürederivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen | |
ATE478840T1 (de) | 3-aminoazetidinderivate enthaltende pharmazeutische zusammensetzungen, diese derivate und deren herstellung | |
ATE252562T1 (de) | Pyrazolcarbonsäurederivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
DE69630145D1 (de) | Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen | |
ATE309206T1 (de) | Schwefel-substituierte sulfonylaminocarbonsäure n-arylamide, ihre herstellung, ihre anwendung und diese enthaltende pharmazeutische zusammensetzungen | |
DE69606028D1 (de) | Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammensetzung | |
ATE432919T1 (de) | Azetidinderivate, ihre herstellung und sie enthaltende pharmazeutische zusammensetzungen | |
ATE507246T1 (de) | Wasserlösliche eisen-kohlenhydrat-komplexe, deren herstellung und diese enthaltende arzneimittel | |
EE200200130A (et) | Uued farmatseutiliste omadustega aminodikarboksüülhappe derivaadid | |
EE04464B1 (et) | Indalüülasendatud benseenkarboksamiidid, nende valmistamismeetod, kasutamine ja farmatseutilised kompositsioonid | |
DE69902535D1 (de) | Phenoxypropanolamin-derivate, verfahren zu ihrer herstellung und diese enthaltenden pharmazeutischen zusammensetzungen | |
ATE337311T1 (de) | Heterocyclylalkylpiperidinderivate, deren herstellung und zusammensetzungen, die diese derivate enthalten | |
ATE380023T1 (de) | Orale feste pharmazeutische zusammensetzungen zur ph-abhängig mehrphasigen freisetzung | |
DE60045402D1 (de) | Silylalkylplatin (IV) Verbindungen und deren Herstellung | |
DE69927033T2 (de) | 4-aminopyridinderivate, ihre verwendung als arzneimittel und diese enthaltende pharmazeutische zusammensetzungen | |
DE69608680D1 (de) | Taxal derivate, deren herstellung und diese enthaltende pharmazeutische zusammenstellungen | |
DE60304599D1 (de) | Pyridopyrimidinon-derivate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
DE69610085D1 (de) | Taxol derivate,deren herstellung und diese enthaltende pharmazeutische zusammenstellungen | |
ATE204266T1 (de) | Taxoide, ihre herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
ATE222586T1 (de) | Benzolsulfonamidderivate und verfahren zu ihrer herstellung und diese enthaltende pharmazeutische zusammensetzungen | |
DE60200089D1 (de) | Octahydro-2H-pyrido[1,2-a]pyrazinderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen | |
ATE290543T1 (de) | Pharmazeutische zusammensetzungen mit oligosacchariden und deren herstellung | |
DE60300571D1 (de) | [3,4-a:3,4-c]Carbazolderivate, Verfahren zu ihrer Herstellung und diese enthaltende pharmazeutische Zubereitungen | |
DE60126046D1 (de) | Bizyklische Amino-Pyrazon Derivate, deren Herstellung und pharmazeutische Zusammensetzungen | |
DE60210595D1 (de) | Neue 5-thio-ss-d-xylopyranosidderivate, verfahren zu deren herstellung, diese enthaltende pharmazeutische zusammensetzungen und deren therapeutische verwendung |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
UEP | Publication of translation of european patent specification |
Ref document number: 1169316 Country of ref document: EP |
|
EEIH | Change in the person of patent owner | ||
REN | Ceased due to non-payment of the annual fee |