GR3033591T3 - Novel taxoids, preparation thereof, and pharmaceutical compositions containing same - Google Patents

Novel taxoids, preparation thereof, and pharmaceutical compositions containing same

Info

Publication number
GR3033591T3
GR3033591T3 GR20000400102T GR20000400102T GR3033591T3 GR 3033591 T3 GR3033591 T3 GR 3033591T3 GR 20000400102 T GR20000400102 T GR 20000400102T GR 20000400102 T GR20000400102 T GR 20000400102T GR 3033591 T3 GR3033591 T3 GR 3033591T3
Authority
GR
Greece
Prior art keywords
preparation
pharmaceutical compositions
compositions containing
containing same
novel taxoids
Prior art date
Application number
GR20000400102T
Other languages
English (en)
Inventor
Herve Bouchard
Alain Commercon
Original Assignee
Rhone Poulenc Rorer Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of GR3033591T3 publication Critical patent/GR3033591T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
GR20000400102T 1995-04-14 2000-06-01 Novel taxoids, preparation thereof, and pharmaceutical compositions containing same GR3033591T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9504559A FR2732968B1 (fr) 1995-04-14 1995-04-14 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent
PCT/FR1996/000559 WO1996032387A1 (fr) 1995-04-14 1996-04-12 Nouveaux taxoides, leur preparation et les compositions pharmaceutiques qui les contiennent

Publications (1)

Publication Number Publication Date
GR3033591T3 true GR3033591T3 (en) 2000-09-29

Family

ID=9478163

Family Applications (1)

Application Number Title Priority Date Filing Date
GR20000400102T GR3033591T3 (en) 1995-04-14 2000-06-01 Novel taxoids, preparation thereof, and pharmaceutical compositions containing same

Country Status (16)

Country Link
US (1) US5906990A (el)
EP (1) EP0820448B1 (el)
JP (1) JP4308905B2 (el)
AR (1) AR002041A1 (el)
AT (1) ATE193533T1 (el)
AU (1) AU5652296A (el)
DE (1) DE69608680T2 (el)
DK (1) DK0820448T3 (el)
ES (1) ES2148758T3 (el)
FR (1) FR2732968B1 (el)
GR (1) GR3033591T3 (el)
IL (1) IL117878A (el)
PT (1) PT820448E (el)
TW (1) TW349095B (el)
WO (1) WO1996032387A1 (el)
ZA (1) ZA962900B (el)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU7360396A (en) 1995-09-11 1997-04-01 Enzymed, Inc. Biocatalytic methods for synthesizing and identifying biologically active compounds
US6156789A (en) * 1998-03-17 2000-12-05 Rhone-Poulenc Rorer S.A. Method for treating abnormal cell proliferation in the brain
JP2002523364A (ja) * 1998-08-20 2002-07-30 アベンテイス・フアルマ・ソシエテ・アノニム タキソイド誘導体の新規な使用
EP0982028A1 (en) * 1998-08-20 2000-03-01 Aventis Pharma S.A. New use of taxoid derivatives
CA2365776A1 (en) * 1999-05-03 2000-11-09 Alain Renard Method for treating abnormal cell proliferation in the brain
CN1186340C (zh) * 2000-02-02 2005-01-26 佛罗里达州立大学研究基金有限公司 用作抗肿瘤剂的c10碳酸酯取代的紫杉烷
US6649632B2 (en) 2000-02-02 2003-11-18 Fsu Research Foundation, Inc. C10 ester substituted taxanes
CZ20013520A3 (cs) * 2000-02-02 2002-03-13 Florida State University Research Foundation, Inc. C10 - Karbamoyloxy substituované taxany jako protinádorová činidla
WO2002066448A1 (en) * 2001-02-20 2002-08-29 Dabur India Limited Method of preparation of paclitaxel (taxol) using 3-(alk-2-ynyloxy) carbonyl-5-oxazolidine carboxylic acid
FR2853651B1 (fr) * 2003-04-14 2005-05-20 Aventis Pharma Sa Procede de preparation du 4,10 beta-diacetoxy-2 alpha- benzoyloxy-5 beta, 20-epoxy-1, 13 alpha-dihydroxy-9-oxo-19- norcyclopropa[g]tax-11-ene
US6956124B2 (en) 2003-04-14 2005-10-18 Aventis Pharma S.A. Process for the preparation of 4,10β-diacetoxy-2α-benzoyloxy-5β,20-epoxy-1,13α-dihydroxy-9-oxo-19-norcyclopropa[g]tax-11-ene
WO2004103344A1 (en) * 2003-05-20 2004-12-02 Aronex Pharmaceuticals, Inc. Combination chemotherapy comprising a liposomal platinum complex
US7064980B2 (en) * 2003-09-17 2006-06-20 Sandisk Corporation Non-volatile memory and method with bit line coupled compensation
PE20050693A1 (es) * 2004-02-13 2005-09-27 Univ Florida State Res Found Taxanos sustituidos con esteres de ciclopentilo en c10
JP2008530122A (ja) * 2005-02-14 2008-08-07 フロリダ・ステイト・ユニバーシティ・リサーチ・ファウンデイション・インコーポレイテッド Ｃ１０シクロプロピルエステル置換タキサン組成物
US20090076127A1 (en) * 2007-09-19 2009-03-19 Protia, Llc Deuterium-enriched larotaxel
CA2718567A1 (en) * 2008-03-31 2009-12-03 Florida State University Research Foundation, Inc. C(10) ethyl ester and c(10) cyclopropyl ester substituted taxanes
EP2177630A1 (en) * 2008-10-02 2010-04-21 Institut Gustave Roussy Methods for predicting or monitoring whether a patient affected by a cancer is responsive to a treatment with a molecule of the taxoid family

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5294637A (en) * 1992-07-01 1994-03-15 Bristol-Myers Squibb Company Fluoro taxols
US5254580A (en) * 1993-01-19 1993-10-19 Bristol-Myers Squibb Company 7,8-cyclopropataxanes
FR2698871B1 (fr) * 1992-12-09 1995-02-24 Rhone Poulenc Rorer Sa Nouveau taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
FR2710642B1 (fr) * 1993-09-29 1995-11-17 Rhone Poulenc Rorer Sa Nouveaux taxoïdes, leur préparation et les compositions pharmaceutiques qui les contiennent.
US5395850A (en) * 1994-03-10 1995-03-07 Bristol-Myers Squibb Company 6,7-epoxy paclitaxels
FR2718135B1 (fr) * 1994-04-05 1996-04-26 Rhone Poulenc Rorer Sa Procédé de préparation d'hydroxy-7 taxanes.

Also Published As

Publication number Publication date
AU5652296A (en) 1996-10-30
FR2732968B1 (fr) 1997-05-16
TW349095B (en) 1999-01-01
ES2148758T3 (es) 2000-10-16
JPH11503443A (ja) 1999-03-26
AR002041A1 (es) 1998-01-07
FR2732968A1 (fr) 1996-10-18
WO1996032387A1 (fr) 1996-10-17
DE69608680T2 (de) 2000-10-19
DE69608680D1 (de) 2000-07-06
EP0820448B1 (fr) 2000-05-31
PT820448E (pt) 2000-09-29
ZA962900B (en) 1996-07-30
US5906990A (en) 1999-05-25
JP4308905B2 (ja) 2009-08-05
IL117878A (en) 2001-03-19
ATE193533T1 (de) 2000-06-15
DK0820448T3 (da) 2000-08-21
EP0820448A1 (fr) 1998-01-28
IL117878A0 (en) 1996-08-04

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