ATE109145T1 - Heterozyklische acylaminothiazolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen. - Google Patents

Heterozyklische acylaminothiazolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.

Info

Publication number
ATE109145T1
ATE109145T1 AT90403458T AT90403458T ATE109145T1 AT E109145 T1 ATE109145 T1 AT E109145T1 AT 90403458 T AT90403458 T AT 90403458T AT 90403458 T AT90403458 T AT 90403458T AT E109145 T1 ATE109145 T1 AT E109145T1
Authority
AT
Austria
Prior art keywords
heterocyclic
preparation
pharmaceutical preparations
preparations containing
acylaminothiazole derivatives
Prior art date
Application number
AT90403458T
Other languages
English (en)
Inventor
Jean-Pierre Bras
Daniel Frehel
Danielle Gully
Gerard Valette
Original Assignee
Sanofi Elf
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=26227714&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=ATE109145(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Priority claimed from FR8916122A external-priority patent/FR2655344B1/fr
Priority claimed from FR9005669A external-priority patent/FR2661677B1/fr
Application filed by Sanofi Elf filed Critical Sanofi Elf
Application granted granted Critical
Publication of ATE109145T1 publication Critical patent/ATE109145T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/38—Nitrogen atoms
    • C07D277/44—Acylated amino or imino radicals
    • C07D277/46—Acylated amino or imino radicals by carboxylic acids, or sulfur or nitrogen analogues thereof
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425—Thiazoles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/12—Antidiarrhoeals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
AT90403458T 1989-12-06 1990-12-05 Heterozyklische acylaminothiazolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen. ATE109145T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR8916122A FR2655344B1 (fr) 1989-12-06 1989-12-06 Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.
FR9005669A FR2661677B1 (fr) 1990-05-04 1990-05-04 Derives heterocycliques d'acylaminothiazoles, leur preparation et compositions pharmaceutiques en contenant.

Publications (1)

Publication Number Publication Date
ATE109145T1 true ATE109145T1 (de) 1994-08-15

Family

ID=26227714

Family Applications (1)

Application Number Title Priority Date Filing Date
AT90403458T ATE109145T1 (de) 1989-12-06 1990-12-05 Heterozyklische acylaminothiazolderivate, ihre herstellung und diese enthaltende pharmazeutische zubereitungen.

Country Status (20)

Country Link
US (2) US5189049A (de)
EP (1) EP0432040B2 (de)
JP (2) JP2760903B2 (de)
KR (1) KR0147281B1 (de)
AR (1) AR248138A1 (de)
AT (1) ATE109145T1 (de)
AU (1) AU628696B2 (de)
CA (1) CA2031463C (de)
DE (1) DE69011059T3 (de)
DK (1) DK0432040T3 (de)
ES (1) ES2057490T5 (de)
FI (1) FI94249C (de)
GR (1) GR3025940T3 (de)
HK (1) HK1002030A1 (de)
HU (2) HU218276B (de)
IE (1) IE68593B1 (de)
IL (1) IL96577A (de)
LV (1) LV5802B4 (de)
MX (1) MX9203027A (de)
NO (1) NO179584C (de)

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FR2703995B1 (fr) * 1993-04-16 1995-07-21 Sanofi Elf 5-acylamino 1,2,4-thiadiazoles, leur preparation et compositions pharmaceutiques en contenant.
FR2754258B1 (fr) 1996-10-08 1998-12-31 Sanofi Sa Derives d'aminothiazole, leur procede de preparation et les compositions pharmaceutiques les contenant
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ID24372A (id) 1997-10-27 2000-07-13 Agouron Pharma SENYAWA-SENYAWA 4-AMINO-TIAZOL-2-IL SEBAGAI PENGHAMBAT-PENGHAMBAT CDKs
FR2781227B1 (fr) * 1998-07-20 2002-02-22 Sanofi Sa Procede pour la preparation du sel potassique du lintitript
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DE19908538A1 (de) * 1999-02-26 2000-08-31 Aventis Pharma Gmbh Polycyclische 2-Amino-Thiazol Systeme, Verfahren zu ihrer Herstellung und Arzneimittel enthaltend diese Verbindungen
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US6340683B1 (en) 1999-04-22 2002-01-22 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (triazines)
US6222040B1 (en) 1999-06-30 2001-04-24 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
US6214853B1 (en) 1999-06-30 2001-04-10 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (bicyclics)
US6225330B1 (en) 1999-06-30 2001-05-01 Synaptic Pharmaceutical Corporation Selective NPY (Y5) antagonists (tricyclics)
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CN105518005B (zh) 2013-07-02 2018-07-20 百时美施贵宝公司 作为rock抑制剂的三环吡啶-甲酰胺衍生物
CN113321640B (zh) * 2017-06-22 2023-06-09 中国科学院广州生物医药与健康研究院 一种吲哚类化合物及其应用
CN112040945A (zh) 2018-06-12 2020-12-04 Vtv治疗有限责任公司 葡萄糖激酶激活剂与胰岛素或胰岛素类似物组合的治疗用途

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Also Published As

Publication number Publication date
GR3025940T3 (en) 1998-04-30
AU6777990A (en) 1991-06-20
DK0432040T3 (da) 1994-10-31
IL96577A0 (en) 1991-09-16
FI94249C (fi) 1995-08-10
DE69011059T2 (de) 1995-03-02
IL96577A (en) 1994-06-24
NO179584B (no) 1996-07-29
NO905255D0 (no) 1990-12-05
CA2031463C (en) 2000-07-25
EP0432040A1 (de) 1991-06-12
FI94249B (fi) 1995-04-28
HUT59400A (en) 1992-05-28
ES2057490T5 (es) 1998-03-16
JP3035253B2 (ja) 2000-04-24
DE69011059T3 (de) 1998-04-09
NO905255L (no) 1991-06-07
MX9203027A (es) 1992-07-01
JPH10130147A (ja) 1998-05-19
FI905941A (fi) 1991-06-07
USRE37094E1 (en) 2001-03-13
HU908075D0 (en) 1991-06-28
HK1002030A1 (en) 1998-07-24
IE68593B1 (en) 1996-06-26
EP0432040B2 (de) 1997-12-17
LV5802B4 (lv) 1997-08-20
AR248138A1 (es) 1995-06-30
HU211866A9 (en) 1995-12-28
CA2031463A1 (en) 1991-06-07
HU218276B (en) 2000-07-28
JP2760903B2 (ja) 1998-06-04
FI905941A0 (fi) 1990-12-03
EP0432040B1 (de) 1994-07-27
ES2057490T3 (es) 1994-10-16
NO179584C (no) 1996-11-06
KR910011814A (ko) 1991-08-07
AU628696B2 (en) 1992-09-17
IE904310A1 (en) 1991-06-19
KR0147281B1 (ko) 1998-08-17
US5189049A (en) 1993-02-23
JPH03279374A (ja) 1991-12-10
LV5802A4 (lv) 1997-02-20
DE69011059D1 (de) 1994-09-01

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