DE3776620D1 - 3-propenylcephemderivate, ihre herstellung, zwischenverbindungen, pharmazeutische praeparate und anwendung. - Google Patents

3-propenylcephemderivate, ihre herstellung, zwischenverbindungen, pharmazeutische praeparate und anwendung.

Info

Publication number
DE3776620D1
DE3776620D1 DE8787114843T DE3776620T DE3776620D1 DE 3776620 D1 DE3776620 D1 DE 3776620D1 DE 8787114843 T DE8787114843 T DE 8787114843T DE 3776620 T DE3776620 T DE 3776620T DE 3776620 D1 DE3776620 D1 DE 3776620D1
Authority
DE
Germany
Prior art keywords
propenylcephemic
derivatives
production
application
pharmaceutical preparations
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE8787114843T
Other languages
English (en)
Inventor
Takashi Kamiya
Toshihiko Naito
Shigeto Negi
Yuuki Komatu
Yasunobu Kai
Takaharu Nakamura
Isao Sugiyama
Yoshimasa Machida
Seiichiro Nomoto
Kyosuke Kitoh
Kanemasa Katsu
Hiroshi Yamauchi
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Application granted granted Critical
Publication of DE3776620D1 publication Critical patent/DE3776620D1/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
DE8787114843T 1986-10-13 1987-10-12 3-propenylcephemderivate, ihre herstellung, zwischenverbindungen, pharmazeutische praeparate und anwendung. Expired - Fee Related DE3776620D1 (de)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
JP24148086 1986-10-13
JP26279986 1986-11-06
JP29257486 1986-12-10
JP2186687 1987-02-03
JP21923087 1987-09-03
JP22214787 1987-09-07

Publications (1)

Publication Number Publication Date
DE3776620D1 true DE3776620D1 (de) 1992-03-19

Family

ID=27549011

Family Applications (1)

Application Number Title Priority Date Filing Date
DE8787114843T Expired - Fee Related DE3776620D1 (de) 1986-10-13 1987-10-12 3-propenylcephemderivate, ihre herstellung, zwischenverbindungen, pharmazeutische praeparate und anwendung.

Country Status (14)

Country Link
US (4) US4921850A (de)
EP (1) EP0264091B1 (de)
CN (1) CN1020104C (de)
CA (1) CA1290748C (de)
DE (1) DE3776620D1 (de)
DK (1) DK174995B1 (de)
ES (1) ES2039223T3 (de)
FI (1) FI89169C (de)
GR (1) GR3003841T3 (de)
HU (1) HU207088B (de)
IL (1) IL84128A (de)
NO (1) NO170021C (de)
NZ (1) NZ222116A (de)
PT (1) PT85906B (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5373000A (en) * 1985-12-26 1994-12-13 Eisai Co., Ltd. 7Beta-(thiadiazolyl)-2-iminoacetamido-3cephem compounds
EP0764648B1 (de) * 1988-03-16 2002-01-16 Eisai Co., Ltd. Cephemderivate und Verfahren zu ihrer Herstellung
CS273349B2 (en) * 1988-03-31 1991-03-12 Hoffmann La Roche Method of cephalosporin's new derivatives production
ES2059947T3 (es) * 1989-09-30 1994-11-16 Eisai Co Ltd Preparados inyectables que contienen cefalosporina y utilizacion de los mismos.
FR2663332B1 (fr) * 1990-06-15 1997-11-07 Roussel Uclaf Nouvelles cephalosporines comportant en position 3 un radical propenyle substitue par un ammonium quaternaire, leur procede de preparation, leur application comme medicaments, les compositions les renfermant et les nouveaux intermediaires obtenus.
US5126336A (en) * 1990-08-23 1992-06-30 Bristol-Myers Squibb Company Antibiotic c-3 catechol-substituted cephalosporin compounds, compositions and method of use thereof
AT396108B (de) * 1991-08-21 1993-06-25 Biochemie Gmbh Neues verfahren und neue zwischenprodukte zur herstellung von 7-aminocephalosporansaeurederivaten
US5523400A (en) * 1993-04-16 1996-06-04 Hoffmann-La Roche Inc. Cephalosporin antibiotics
JPH07173168A (ja) * 1993-07-14 1995-07-11 Sumitomo Chem Co Ltd セフェム系化合物、その製法、およびそれのセフェム系抗生物質製造への利用
US6265394B1 (en) 1997-07-31 2001-07-24 Bristol-Myers Squibb Company Bis quaternary MRSA cephem derivatives
US7160537B2 (en) * 2003-12-15 2007-01-09 Siemens Medical Solutions Usa, Inc. Method for preparing radiolabeled thymidine having low chromophoric byproducts
US20110105488A1 (en) * 2008-03-21 2011-05-05 Chlorion Pharma, Inc. Substituted pyrrolidine and piperidine compounds, derivatives thereof, and methods for treating pain
CN114315872A (zh) * 2021-12-25 2022-04-12 海南海灵化学制药有限公司 一种盐酸头孢唑兰中间体的制备方法

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE439312B (sv) * 1977-03-25 1985-06-10 Roussel Uclaf Sett att framstella nya oximderivat av 3-acetoximetyl-7-aminotiazolylacetamido cefalosporansyra
FR2494280A1 (fr) * 1980-11-20 1982-05-21 Rhone Poulenc Ind Nouveaux derives de la cephalosporine et leur preparation
US4408515A (en) * 1981-07-13 1983-10-11 Sciuto Michael N Stringed instrument conversion kit employing combined bridge/tuning mechanism
US4406899A (en) * 1982-03-04 1983-09-27 Bristol-Myers Company Cephalosporins
US4457929A (en) * 1982-03-29 1984-07-03 Bristol-Myers Company 3-Quaternary ammonium methyl)-substituted cephalosporin derivatives
DE3247613A1 (de) * 1982-12-23 1984-07-05 Hoechst Ag, 6230 Frankfurt Cephalosporinderivate und verfahren zu ihrer herstellung
US4486586A (en) * 1983-02-10 1984-12-04 Bristol-Myers Company Cephalosporin derivatives
US4525473A (en) * 1983-03-30 1985-06-25 Bristol-Myers Company Cephalosporins
ZA847825B (en) * 1983-10-08 1985-05-29 Hoechst Ag Caphalosporin derivatives and processes for their preparations
GB8406231D0 (en) * 1984-03-09 1984-04-11 Fujisawa Pharmaceutical Co Cephem compounds
JPS60197692A (ja) * 1984-03-19 1985-10-07 Eisai Co Ltd ７−アミノチアゾリルアセトアミドセフエム誘導体
JPS60197693A (ja) * 1984-03-19 1985-10-07 Eisai Co Ltd ３−（キヌクリジニウム）メチル−３−セフエム誘導体
US4751295A (en) * 1984-04-09 1988-06-14 Bristol-Myers Company Cephalosporin derivatives
CA1276929C (en) * 1984-04-09 1990-11-27 Masahisa Oka Cephalosporin antibacterial agents
DK500285A (da) * 1984-11-02 1986-05-03 Glaxo Group Ltd Cephalosporinantibiotika
US4761410A (en) * 1985-01-14 1988-08-02 Fujisawa Pharmaceutical Co., Ltd. Cephem Compounds
GB2177691A (en) * 1985-07-18 1987-01-28 Glaxo Group Ltd Cephalosporin antibiotics

Also Published As

Publication number Publication date
FI89169C (fi) 1993-08-25
PT85906A (en) 1987-11-01
NO170021B (no) 1992-05-25
IL84128A0 (en) 1988-03-31
US4921850A (en) 1990-05-01
EP0264091A2 (de) 1988-04-20
EP0264091A3 (en) 1989-12-27
NO170021C (no) 1992-09-02
NO874255D0 (no) 1987-10-12
US5066812A (en) 1991-11-19
US5006649A (en) 1991-04-09
PT85906B (pt) 1990-08-31
US5089491A (en) 1992-02-18
CA1290748C (en) 1991-10-15
ES2039223T3 (es) 1993-09-16
EP0264091B1 (de) 1992-02-05
CN87107610A (zh) 1988-06-01
FI874492A (fi) 1988-04-14
CN1020104C (zh) 1993-03-17
IL84128A (en) 1992-12-01
FI874492A0 (fi) 1987-10-12
GR3003841T3 (de) 1993-03-16
HU207088B (en) 1993-03-01
FI89169B (fi) 1993-05-14
NZ222116A (en) 1990-08-28
DK531387D0 (da) 1987-10-12
NO874255L (no) 1988-04-14
DK174995B1 (da) 2004-04-13
DK531387A (da) 1988-04-14
HUT47119A (en) 1989-01-30

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee