DK0680488T3 - 2,6-Diaminopurinderivater - Google Patents
2,6-DiaminopurinderivaterInfo
- Publication number
- DK0680488T3 DK0680488T3 DK94905100T DK94905100T DK0680488T3 DK 0680488 T3 DK0680488 T3 DK 0680488T3 DK 94905100 T DK94905100 T DK 94905100T DK 94905100 T DK94905100 T DK 94905100T DK 0680488 T3 DK0680488 T3 DK 0680488T3
- Authority
- DK
- Denmark
- Prior art keywords
- diaminopurine derivatives
- diaminopurine
- derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
- A61P35/04—Antineoplastic agents specific for metastasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
- C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
- C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
- C07H19/16—Purine radicals
- C07H19/167—Purine radicals with ribosyl as the saccharide radical
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Molecular Biology (AREA)
- Immunology (AREA)
- Genetics & Genomics (AREA)
- Biotechnology (AREA)
- Biochemistry (AREA)
- Pulmonology (AREA)
- Oncology (AREA)
- Cardiology (AREA)
- Transplantation (AREA)
- Heart & Thoracic Surgery (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Saccharide Compounds (AREA)
- Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
- Hydrogenated Pyridines (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB939301000A GB9301000D0 (en) | 1993-01-20 | 1993-01-20 | Chemical compounds |
PCT/EP1994/000145 WO1994017090A1 (en) | 1993-01-20 | 1994-01-18 | 2,6-diaminopurine derivatives |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0680488T3 true DK0680488T3 (da) | 1999-01-25 |
Family
ID=10728948
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK94905100T DK0680488T3 (da) | 1993-01-20 | 1994-01-18 | 2,6-Diaminopurinderivater |
Country Status (29)
Country | Link |
---|---|
US (2) | US5925624A (cs) |
EP (1) | EP0680488B1 (cs) |
JP (1) | JP3768232B2 (cs) |
KR (1) | KR960700261A (cs) |
CN (1) | CN1043997C (cs) |
AP (1) | AP457A (cs) |
AT (1) | ATE164849T1 (cs) |
AU (1) | AU679714B2 (cs) |
CA (1) | CA2153688A1 (cs) |
CZ (1) | CZ187995A3 (cs) |
DE (1) | DE69409503T2 (cs) |
DK (1) | DK0680488T3 (cs) |
EC (1) | ECSP941104A (cs) |
ES (1) | ES2117249T3 (cs) |
FI (1) | FI953489L (cs) |
GB (1) | GB9301000D0 (cs) |
HU (1) | HU211914A9 (cs) |
IL (1) | IL108372A (cs) |
IS (1) | IS4121A (cs) |
NO (1) | NO305603B1 (cs) |
NZ (1) | NZ259880A (cs) |
PE (1) | PE54194A1 (cs) |
PL (1) | PL309975A1 (cs) |
RU (1) | RU2129561C1 (cs) |
SI (1) | SI9400021A (cs) |
SK (1) | SK281229B6 (cs) |
TW (1) | TW267168B (cs) |
WO (1) | WO1994017090A1 (cs) |
ZA (1) | ZA94335B (cs) |
Families Citing this family (101)
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US6413974B1 (en) | 1998-02-26 | 2002-07-02 | Aventis Pharmaceuticals Inc. | 6,9,-disubstituted 2-[trans-(4-aminocyclohexyl) amino] purines |
US6479487B1 (en) | 1998-02-26 | 2002-11-12 | Aventis Pharmaceuticals Inc. | 6, 9-disubstituted 2-[trans-(4-aminocyclohexyl)amino] purines |
AU748178B2 (en) * | 1998-02-26 | 2002-05-30 | Aventis Holdings Inc. | 6,9-disubstituted 2-(trans-(4- aminocyclohexyl) amino)purines |
AU763658B2 (en) | 1998-06-02 | 2003-07-31 | Osi Pharmaceuticals, Inc. | Pyrrolo(2,3d)pyrimidine compositions and their use |
US6686366B1 (en) | 1998-06-02 | 2004-02-03 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
US6878716B1 (en) | 1998-06-02 | 2005-04-12 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A1 receptor and uses thereof |
GB9813540D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
GB9813565D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
GB9813554D0 (en) * | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
GB9813535D0 (en) | 1998-06-23 | 1998-08-19 | Glaxo Group Ltd | Chemical compounds |
HRP20000894A2 (en) | 1998-06-23 | 2001-12-31 | Glaxo Group Ltd | 2-(purin-9-yl)-tetrahydrofuran-3,4-diol derivatives |
RU2258071C2 (ru) * | 1999-05-24 | 2005-08-10 | Юниверсити Оф Вирджиния Пэйтент Фаундейшн | Производные 2-алкиниладенозина для борьбы с воспалительной реакцией |
US7160890B2 (en) | 1999-12-02 | 2007-01-09 | Osi Pharmaceuticals, Inc. | Compounds specific to adenosine A3 receptor and uses thereof |
US6664252B2 (en) | 1999-12-02 | 2003-12-16 | Osi Pharmaceuticals, Inc. | 4-aminopyrrolo[2,3-d]pyrimidine compounds specific to adenosine A2a receptor and uses thereof |
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BE789773A (fr) * | 1971-10-08 | 1973-04-06 | Schering Ag | Adenosines n6 -substituees et leur procede de |
CA1239397A (en) * | 1983-08-01 | 1988-07-19 | James A. Bristol | N.sup.6-substituted adenosines |
DE3406533A1 (de) * | 1984-02-23 | 1985-08-29 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verwendung von adenosin-derivaten als antiallergica und arzneimittel, die diese enthalten |
EP0300145A3 (en) * | 1984-04-18 | 1989-08-30 | Whitby Research Incorporated | N-6 phenyl substituted adenosine derivatives as cardiac vasodilators |
US4663313A (en) * | 1984-10-26 | 1987-05-05 | Warner-Lambert Company | N6 -tricyclic adenosines for treating hypertension |
US4738954A (en) | 1985-11-06 | 1988-04-19 | Warner-Lambert Company | Novel N6 -substituted-5'-oxidized adenosine analogs |
US5106837A (en) * | 1988-03-16 | 1992-04-21 | The Scripps Research Institute | Adenosine derivatives with therapeutic activity |
US4757747A (en) * | 1986-04-08 | 1988-07-19 | Vickers, Incorporated | Power transmission |
AU8274187A (en) * | 1986-10-31 | 1988-05-25 | Warner-Lambert Company | Heteroaromatic derivatives of adenosine |
FI880405A7 (fi) * | 1987-02-04 | 1988-08-05 | Ciba Geigy Ag | Adenosin-5'-karboxamidderivat. |
US4968697A (en) * | 1987-02-04 | 1990-11-06 | Ciba-Geigy Corporation | 2-substituted adenosine 5'-carboxamides as antihypertensive agents |
LU87181A1 (fr) * | 1987-04-06 | 1988-11-17 | Sandoz Sa | Nouveaux derives de l'acide furannuronique,leur preparation et leur utilisation comme medicaments |
DE3810551A1 (de) * | 1987-04-06 | 1988-11-03 | Sandoz Ag | Neue ribofuranuronsaeure-derivate |
US5219840A (en) * | 1987-04-06 | 1993-06-15 | Sandoz Ltd. | Antihypertensive 9-(2,N6 -disubstituted adenyl) ribofuranuronic acid derivatives |
KR0138996B1 (ko) * | 1988-03-16 | 1998-04-30 | 레이몬드 에이치. 칸 | 치환된 아데닌 유도체 및 이를 함유하는 약제학적 조성물 |
JPH0725785B2 (ja) * | 1989-01-11 | 1995-03-22 | 日本臓器製薬株式会社 | アデノシン誘導体及び該化合物を有効成分として含有する医薬組成物 |
DE3924424A1 (de) * | 1989-07-24 | 1991-01-31 | Boehringer Mannheim Gmbh | Nucleosid-derivate, verfahren zu deren herstellung, deren verwendung als arzneimittel sowie deren verwendung bei der nucleinsaeure-sequenzierung |
CA2028002A1 (en) * | 1989-10-19 | 1991-04-20 | Daniel P. Becker | Method of treating gastrointestinal motility disorders |
US5459255A (en) * | 1990-01-11 | 1995-10-17 | Isis Pharmaceuticals, Inc. | N-2 substituted purines |
DE4025879A1 (de) * | 1990-08-16 | 1992-02-20 | Sandoz Ag | Neue adenosin derivate, deren herstellung und verwendung |
FR2687678B1 (fr) * | 1992-01-31 | 1995-03-31 | Union Pharma Scient Appl | Nouveaux derives de l'adenosine, leurs procedes de preparation, compositions pharmaceutiques les contenant. |
EP0708781B1 (en) * | 1993-07-13 | 2001-10-04 | THE UNITED STATES OF AMERICA, as represented by THE SECRETARY, Department of Health and Human Services | A 3 adenosine receptor agonists |
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1993
- 1993-01-20 GB GB939301000A patent/GB9301000D0/en active Pending
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1994
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- 1994-01-18 AP APAP/P/1994/000613A patent/AP457A/en active
- 1994-01-18 JP JP51665294A patent/JP3768232B2/ja not_active Expired - Fee Related
- 1994-01-18 CN CN94191527A patent/CN1043997C/zh not_active Expired - Fee Related
- 1994-01-18 CZ CZ951879A patent/CZ187995A3/cs unknown
- 1994-01-18 AT AT94905100T patent/ATE164849T1/de not_active IP Right Cessation
- 1994-01-18 RU RU95122754A patent/RU2129561C1/ru active
- 1994-01-18 DE DE69409503T patent/DE69409503T2/de not_active Expired - Lifetime
- 1994-01-18 SK SK918-95A patent/SK281229B6/sk unknown
- 1994-01-18 ZA ZA94335A patent/ZA94335B/xx unknown
- 1994-01-18 ES ES94905100T patent/ES2117249T3/es not_active Expired - Lifetime
- 1994-01-18 AU AU58851/94A patent/AU679714B2/en not_active Ceased
- 1994-01-18 PL PL94309975A patent/PL309975A1/xx unknown
- 1994-01-18 KR KR1019950702963A patent/KR960700261A/ko not_active Abandoned
- 1994-01-18 NZ NZ259880A patent/NZ259880A/en unknown
- 1994-01-18 FI FI953489A patent/FI953489L/fi unknown
- 1994-01-18 CA CA002153688A patent/CA2153688A1/en not_active Abandoned
- 1994-01-18 DK DK94905100T patent/DK0680488T3/da active
- 1994-01-18 EP EP94905100A patent/EP0680488B1/en not_active Expired - Lifetime
- 1994-01-18 WO PCT/EP1994/000145 patent/WO1994017090A1/en not_active Application Discontinuation
- 1994-01-18 US US08/446,727 patent/US5925624A/en not_active Expired - Fee Related
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- 1994-05-30 TW TW083104895A patent/TW267168B/zh active
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1995
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1997
- 1997-09-22 US US08/934,540 patent/US5889178A/en not_active Expired - Lifetime
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