DK0672162T3 - Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter - Google Patents

Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter

Info

Publication number
DK0672162T3
DK0672162T3 DK93906156T DK93906156T DK0672162T3 DK 0672162 T3 DK0672162 T3 DK 0672162T3 DK 93906156 T DK93906156 T DK 93906156T DK 93906156 T DK93906156 T DK 93906156T DK 0672162 T3 DK0672162 T3 DK 0672162T3
Authority
DK
Denmark
Prior art keywords
taxanes
taxol
taxus species
cell cultures
increased production
Prior art date
Application number
DK93906156T
Other languages
Danish (da)
English (en)
Inventor
Venkataraman Bringi
Prakash G Kadkade
Original Assignee
Phyton Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27126086&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0672162(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Phyton Inc filed Critical Phyton Inc
Application granted granted Critical
Publication of DK0672162T3 publication Critical patent/DK0672162T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P17/00—Preparation of heterocyclic carbon compounds with only O, N, S, Se or Te as ring hetero atoms
    • C12P17/02—Oxygen as only ring hetero atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/0018—Culture media for cell or tissue culture
    • C12N5/0025—Culture media for plant cell or plant tissue culture
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/04—Plant cells or tissues

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Botany (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Epoxy Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK93906156T 1992-02-20 1993-02-22 Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter DK0672162T3 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US83914492A 1992-02-20 1992-02-20
US07/874,344 US5407816A (en) 1992-02-20 1992-04-24 Enhanced production of taxol and taxanes by cell cultures of taxus species
PCT/US1993/001576 WO1993017121A1 (en) 1992-02-20 1993-02-22 Enhanced production of taxol and taxanes by cell cultures of taxus species

Publications (1)

Publication Number Publication Date
DK0672162T3 true DK0672162T3 (da) 2000-12-18

Family

ID=27126086

Family Applications (2)

Application Number Title Priority Date Filing Date
DK93906156T DK0672162T3 (da) 1992-02-20 1993-02-22 Forøget produktion af taxol og taxaner ved hjælp af cellekulturer af Taxus-arter
DK99202507T DK0960944T3 (da) 1992-02-20 1993-02-22 Forbedret produktion af taxol og taxaner fra cellekulturer af taxus-arter

Family Applications After (1)

Application Number Title Priority Date Filing Date
DK99202507T DK0960944T3 (da) 1992-02-20 1993-02-22 Forbedret produktion af taxol og taxaner fra cellekulturer af taxus-arter

Country Status (16)

Country Link
US (1) US5407816A (es)
EP (3) EP0672162B1 (es)
JP (5) JP3513151B2 (es)
KR (6) KR100285788B1 (es)
AT (3) ATE504659T1 (es)
AU (1) AU672194B2 (es)
CA (1) CA2130745C (es)
DE (3) DE69334352D1 (es)
DK (2) DK0672162T3 (es)
ES (3) ES2150938T3 (es)
GR (1) GR3034722T3 (es)
HK (2) HK1024936A1 (es)
NZ (1) NZ249734A (es)
PT (2) PT672162E (es)
SG (1) SG46427A1 (es)
WO (1) WO1993017121A1 (es)

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US5850032A (en) * 1992-04-01 1998-12-15 Union Camp Corporation Method for production of plant biological products in precocious neomorphic embryoids
CA2434692A1 (en) * 1992-04-07 1993-10-08 Paul M. Cino Callus cell induction and the preparation of taxanes
CA2136213A1 (en) * 1992-05-21 1993-11-25 Richard N. Arteca Cultured taxu tissues as a source of taxol, related taxanes and other novel anti-tumor/anti-viral compounds
JP2967532B2 (ja) * 1992-06-11 1999-10-25 日石三菱株式会社 タキサン類化合物の製造方法
US5981568A (en) 1993-01-28 1999-11-09 Neorx Corporation Therapeutic inhibitor of vascular smooth muscle cells
KR950005081B1 (ko) * 1993-07-06 1995-05-18 산림청임목육종연구소 주목 종자의 씨눈 유래의 체세포배 및 체세포배성세포 혹은 그 배양배지로부터 택솔(Taxol) 및 그 유도체를 생산하는 방법
DE69431135T2 (de) * 1993-11-15 2003-03-27 Mitsui Chemicals Inc Methode zur Herstellung von Taxan-Typ Diterpen und Methode zur Gewinnung von Kulturzellen die Taxan-Typ Diterpen in hohen Ausbeuten herstellen
IL113447A (en) * 1994-04-22 1999-01-26 Us Agriculture Attractant for controlling insects and apparatus containing the same
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US5900367A (en) * 1995-04-29 1999-05-04 Samyang Genex Co., Ltd. Method for purifying taxol from taxus biomass
WO1996034522A1 (en) * 1995-05-05 1996-11-07 Union Camp Corporation Method for production of plant biological products in precocious neomorphic embryoids
AU724476B2 (en) * 1995-05-19 2000-09-21 Galileo Pharmaceuticals, Inc. Manipulation of plant cell and tissue cultures
EP1538214A1 (en) * 1996-05-24 2005-06-08 Phyton, Inc. Enhanced production of taxanes by cell cultures of taxus species
EP1512398A1 (en) 1997-03-31 2005-03-09 Boston Scientific Limited Intravascular stent with cytoskeletal inhibitors for the prevention of restenosis
US5801193A (en) * 1997-04-15 1998-09-01 Immune Modulation, Inc. Compositions and methods for immunosuppressing
KR100287465B1 (ko) 1997-06-25 2001-05-02 나까니시 히로유끼 탁산형 디테르펜의 제조방법
KR100266448B1 (ko) * 1997-06-26 2000-09-15 박종헌 식물세포 배양 중의 온도변화에 의한 택솔의 대량생산 방법
WO1999036413A1 (en) 1998-01-14 1999-07-22 Bristol-Myers Squibb Company Novel crystalline complexes of baccatin iii with imidazole, 2-methylimidazole or isopropanol
US6093422A (en) * 1998-01-23 2000-07-25 Zodiac Pool Care, Inc. Biocidal compositions for treating water
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FR2800740B1 (fr) * 1999-11-08 2002-10-11 Lorraine Inst Nat Polytech Procede de production de metabolites a partir de vegetaux en culture hors sol
JP2004501143A (ja) 2000-06-22 2004-01-15 ニトロメド　インコーポレーテッド ニトロソ化およびニトロシル化タキサン、組成物および使用方法
US7045354B2 (en) * 2000-11-14 2006-05-16 The Regents Of The University Of California Process for scaled-up production of recombinant proteins using transgenic plant suspension cultures
US6365407B1 (en) * 2001-03-05 2002-04-02 Council Of Scientific & Industrial Research Culture medium composition useful for induction and proliferation of Taxus calli
US20030091659A1 (en) * 2001-11-09 2003-05-15 Avon Products, Inc. Topical composition having undifferentiated plant seed cells and method for using same
US20030124205A1 (en) * 2001-12-28 2003-07-03 Avon Products, Inc. Topical cosmetic composition having a natural plant active ingredient and method of using same
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JP5211296B2 (ja) 2005-10-31 2013-06-12 株式会社ウンファ 同期化した植物細胞培養による二次代謝産物の大量生産の安定化
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CN101319199B (zh) * 2007-06-08 2010-10-27 中国科学院大连化学物理研究所 一种利用中国红豆杉细胞诱导产生紫杉烷的方法
KR101064518B1 (ko) * 2007-09-21 2011-09-19 주식회사 운화 저장근을 가지는 초본식물의 형성층 유래 식물줄기세포주 및 이의 분리방법
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KR101100867B1 (ko) * 2008-05-14 2012-01-02 주식회사 운화 주목의 형성층 또는 전형성층 유래 식물줄기세포주를 유효성분으로 함유하는 항산화, 항염증 또는 항노화용 조성물
US8713329B2 (en) * 2009-02-26 2014-04-29 Red Hat, Inc. Authenticated secret sharing
JP5789595B2 (ja) 2009-04-03 2015-10-07 ダイアナプラントサイエンシズ エス．アー．エス． 植物の細胞培養物からのプロシアニジンの産生および抽出
WO2010137879A2 (ko) * 2009-05-26 2010-12-02 주식회사 운화 버드나무과의 형성층 유래 식물줄기세포 및 이의 분리배양방법
WO2010137877A2 (ko) * 2009-05-26 2010-12-02 주식회사 운화 국화과의 형성층 유래 식물줄기세포 및 이의 분리배양방법
EP2436759A2 (en) * 2009-05-28 2012-04-04 Unhwa Corporation Plant stem cell derived from cambium of family solanaceae, and method for isolating and culturing same
CN101671319B (zh) * 2009-09-18 2012-02-29 应成杰 红豆杉无毒提取物的提取工艺
JP2013538590A (ja) 2010-10-04 2013-10-17 ダイアナプラントサイエンシズ エス．アー．エス． 植物の細胞培養物由来のプロシアニジンの生産及び抽出
JP2012217441A (ja) * 2011-04-14 2012-11-12 Housetec Inc タキサン類の生産方法、およびカルス誘導方法
CN102715086B (zh) * 2012-06-19 2014-04-16 湖南农业大学 一种红豆杉试管苗诱导获得愈伤组织和悬浮细胞的方法
CN102715085B (zh) * 2012-06-19 2014-04-16 湖南农业大学 一种诱导红豆杉种子种胚获得愈伤组织和悬浮细胞的方法
CN103058961B (zh) * 2013-01-28 2015-04-29 普洱市红宝生物科技有限公司 从云南红豆杉中提取紫杉醇的方法
CN103570647A (zh) * 2013-11-06 2014-02-12 湖南农业大学 从红豆杉细胞培养液中制备高纯度紫杉醇的方法
KR101603539B1 (ko) * 2014-08-11 2016-03-15 영남대학교 산학협력단 택솔을 생산하는 콜레토트리쿰 데마티움 균주 및 그 용도
KR101786448B1 (ko) 2015-08-24 2017-10-18 영남대학교 산학협력단 택솔을 생산하는 트라이코더마 비리데슨스 tx1 균주 및 이의 용도
CN109022510A (zh) * 2018-08-23 2018-12-18 吉首大学 一种利用南方红豆杉菌根菌与活组织细胞共培养生产紫杉醇及10-dabⅲ的方法
CN110441439B (zh) * 2019-07-01 2022-03-01 杭州师范大学 区分密叶红豆杉和云南红豆杉的代谢标志物及其检测方法
WO2022162101A1 (en) * 2021-01-28 2022-08-04 Phyto-Technics Bv Production of taxol from taxus cuttings

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
JPH03216123A (ja) * 1990-01-17 1991-09-24 Nitsusen Kagaku Kogyo Kk 培養植物体の増殖促進方法
CA2080000A1 (en) * 1991-02-12 1992-08-13 Koji Saito Process for producing taxol by cell culture of taxus species
US5407816A (en) * 1992-02-20 1995-04-18 Phyton Catalytic, Inc. Enhanced production of taxol and taxanes by cell cultures of taxus species

Also Published As

Publication number Publication date
KR100392036B1 (ko) 2003-07-16
KR20110079863A (ko) 2011-07-08
DE69333358T2 (de) 2004-08-19
KR950700996A (ko) 1995-02-20
WO1993017121A1 (en) 1993-09-02
JP2008131955A (ja) 2008-06-12
EP0960944A1 (en) 1999-12-01
KR20090116792A (ko) 2009-11-11
CA2130745A1 (en) 1993-09-02
ATE256197T1 (de) 2003-12-15
HK1024936A1 (en) 2000-10-27
KR20070104684A (ko) 2007-10-26
JP3513151B2 (ja) 2004-03-31
SG46427A1 (en) 1998-02-20
DK0960944T3 (da) 2004-04-05
JPH07506721A (ja) 1995-07-27
PT960944E (pt) 2004-04-30
JP2004000285A (ja) 2004-01-08
PT672162E (pt) 2001-01-31
HK1003718A1 (en) 1998-11-06
GR3034722T3 (en) 2001-01-31
KR20040000390A (ko) 2004-01-03
DE69329154D1 (de) 2000-09-07
ATE195146T1 (de) 2000-08-15
ATE504659T1 (de) 2011-04-15
EP0672162A4 (en) 1995-11-29
JP2009183305A (ja) 2009-08-20
EP1378574A1 (en) 2004-01-07
DE69334352D1 (de) 2011-05-19
EP0672162B1 (en) 2000-08-02
ES2213328T3 (es) 2004-08-16
EP1378574B1 (en) 2011-04-06
KR100285788B1 (ko) 2001-05-02
DE69333358D1 (de) 2004-01-22
EP0672162A1 (en) 1995-09-20
DE69329154T2 (de) 2001-06-07
AU672194B2 (en) 1996-09-26
EP0960944B1 (en) 2003-12-10
ES2361150T3 (es) 2011-06-14
AU3729193A (en) 1993-09-13
JP2005348751A (ja) 2005-12-22
NZ249734A (en) 1996-08-27
US5407816A (en) 1995-04-18
ES2150938T3 (es) 2000-12-16
CA2130745C (en) 2008-01-22

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