DE870837T1 - Verfahren zur Herstellung von Polyester-Biopolymeren - Google Patents

Verfahren zur Herstellung von Polyester-Biopolymeren

Info

Publication number
DE870837T1
DE870837T1 DE0870837T DE97203215T DE870837T1 DE 870837 T1 DE870837 T1 DE 870837T1 DE 0870837 T DE0870837 T DE 0870837T DE 97203215 T DE97203215 T DE 97203215T DE 870837 T1 DE870837 T1 DE 870837T1
Authority
DE
Germany
Prior art keywords
phb
polymers
pha
polymerase
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
DE0870837T
Other languages
English (en)
Other versions
DE29703215U1 (de
Inventor
Oliver P Peoples
Anthony J Sinskey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23491962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE870837(T1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of DE870837T1 publication Critical patent/DE870837T1/de
Pending legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE0870837T 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren Pending DE870837T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US37815589A 1989-07-10 1989-07-10

Publications (1)

Publication Number Publication Date
DE870837T1 true DE870837T1 (de) 1999-09-16

Family

ID=23491962

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69032713T Expired - Lifetime DE69032713T2 (de) 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren
DE69034017T Expired - Lifetime DE69034017T2 (de) 1989-07-10 1990-07-10 Eine zur Herstellung von Polyhydroxybutyrat oder einem anderen Polyhydroxyalkanoat geeignete Pflanze oder pflanzliche Zelle
DE0870837T Pending DE870837T1 (de) 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren

Family Applications Before (2)

Application Number Title Priority Date Filing Date
DE69032713T Expired - Lifetime DE69032713T2 (de) 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren
DE69034017T Expired - Lifetime DE69034017T2 (de) 1989-07-10 1990-07-10 Eine zur Herstellung von Polyhydroxybutyrat oder einem anderen Polyhydroxyalkanoat geeignete Pflanze oder pflanzliche Zelle

Country Status (8)

Country Link
EP (2) EP0870837B1 (de)
JP (8) JPH05500751A (de)
AT (2) ATE172497T1 (de)
CA (1) CA2062816C (de)
DE (3) DE69032713T2 (de)
DK (1) DK0482077T3 (de)
ES (2) ES2131489T3 (de)
WO (1) WO1991000917A1 (de)

Families Citing this family (59)

* Cited by examiner, † Cited by third party
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US5480794A (en) * 1987-06-29 1996-01-02 Massachusetts Institute Of Technology And Metabolix, Inc. Overproduction and purification of soluble PHA synthase
GB9108756D0 (en) 1991-04-24 1991-06-12 Ici Plc Production of polyalkanoate in plants
GB9115245D0 (en) * 1991-07-16 1991-08-28 Ici Plc Production of polyalkanoate
US5610041A (en) * 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
DE69233512T2 (de) * 1991-07-19 2005-10-13 Michigan State University, East Lansing Transgene pflanzen die polyhydroxyalkanoate produzieren
US5569595A (en) * 1991-09-27 1996-10-29 Center For Innovative Technology Production of poly-β-hydroxybutyrate in prokaryotic host cells
GB9223332D0 (en) * 1992-11-06 1992-12-23 Ici Plc Production of polyhydroxyalkanoate in plants
WO1994012014A1 (en) * 1992-11-20 1994-06-09 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
EP0742828A1 (de) * 1994-02-03 1996-11-20 Center For Innovative Technology Verbesserte produktion von poly-beta-hydroxyalkanoaten in transformierten prokaryotischen wirten
CN1079835C (zh) * 1994-06-01 2002-02-27 普罗克特和甘保尔公司 利用空气分级作用回收聚羟基链烷酸酯的方法
CA2191713C (en) * 1994-06-01 2000-08-29 Isao Noda Process for recovering polyhydroxyalkanoates using centrifugal fractionation
US6083729A (en) * 1995-10-26 2000-07-04 Metabolix, Inc. Methods for isolating polyhydroxyalkanoates from plants
WO1997022711A1 (en) * 1995-12-19 1997-06-26 Regents Of The University Of Minnesota Metabolic engineering of polyhydroxyalkanoate monomer synthases
GB9605704D0 (en) * 1996-03-19 1996-05-22 Zeneca Ltd Microorganisms and processes using them
WO1997038110A2 (en) * 1996-04-05 1997-10-16 Kieta Holding S.A. Compositions and methods relating to drug discovery and detection and treatment of gastrointestinal diseases
US5811272A (en) * 1996-07-26 1998-09-22 Massachusetts Institute Of Technology Method for controlling molecular weight of polyhydroxyalkanoates
JP3062459B2 (ja) * 1996-08-14 2000-07-10 理化学研究所 ポリエステル重合酵素遺伝子及びポリエステルの製造方法
AU6169498A (en) * 1997-02-13 1998-09-08 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
JPH10276781A (ja) * 1997-04-01 1998-10-20 Rikagaku Kenkyusho ポリエステル重合酵素及び該酵素をコードする遺伝子
US6391611B1 (en) 1997-04-01 2002-05-21 Japan Science And Technology Corporation Polyester synthase and a gene coding for the same
EP0881293A1 (de) * 1997-05-28 1998-12-02 Eidgenössische Technische Hochschule Zürich Institut für Biotechnologie Herstellung von mittelkettigen Poly-3-Hydroxyalkanoaten in E. coli und davon abgeleiteten Monomeren
DE69838768T2 (de) 1997-09-19 2008-10-30 Metabolix, Inc., Cambridge Biologische Systeme zur Herstellung von Polyhydroxyalkanoat-Polymeren die 4-Hy droxysäure enthalten
WO1999035278A1 (en) * 1998-01-05 1999-07-15 Monsanto Company Biosynthesis of medium chain length polyhydroxyalkanoates
DE69903792T2 (de) 1998-01-07 2003-08-14 Metabolix Inc Tierfutterzusammensetzungen
US6586658B1 (en) 1998-03-06 2003-07-01 Metabolix, Inc. Modification of fatty acid metabolism in plants
US6143952A (en) * 1998-03-31 2000-11-07 Regents Of The University Of Minnesota Modified pseudomonas oleovorans phaC1 nucleic acids encoding bispecific polyhydroxyalkanoate polymerase
US6103956A (en) * 1998-03-31 2000-08-15 Regents Of The University Of Minnesota Polyhydroxyalkanoate synthesis in plants
AU757682B2 (en) 1998-04-08 2003-02-27 Metabolix, Inc. Methods for separation and purification of biopolymers
ATE483023T1 (de) 1998-05-22 2010-10-15 Metabolix Inc Polyhydroxyalkanoatbiopolymere
WO2000006762A1 (en) * 1998-07-30 2000-02-10 Metabolix, Inc. Production of block copolymers of polyhydroxyalkanoates in biological systems
ATE317014T1 (de) * 1998-07-30 2006-02-15 Metabolix Inc Bifunktionelle enzyme zur biopolymerherstellung
EP1975236B1 (de) 1998-08-04 2015-05-06 Metabolix, Inc. Herstellung von Polyhydroxyalkanoat aus Polyolen
ATE319835T1 (de) * 1998-08-18 2006-03-15 Metabolix Inc Transgene polyhydroxyalkanoat produzierende mikroben
US6448473B1 (en) 1999-03-05 2002-09-10 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
ES2336641T3 (es) 2000-02-11 2010-04-15 Metabolix, Inc. Constructos de expresion multigenicos que contienen inteinas modificadas.
US6812013B2 (en) 2000-03-30 2004-11-02 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same
JP3848046B2 (ja) * 2000-03-30 2006-11-22 キヤノン株式会社 ポリヒドロキシアルカノエート合成酵素及び該酵素をコードする遺伝子
US6803220B2 (en) 2000-03-30 2004-10-12 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
JP3848048B2 (ja) * 2000-03-30 2006-11-22 キヤノン株式会社 ポリヒドロキシアルカノエート合成酵素及び該酵素をコードする遺伝子
US6875596B2 (en) 2000-03-30 2005-04-05 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
US6803219B2 (en) 2000-03-30 2004-10-12 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
JP3848047B2 (ja) * 2000-03-30 2006-11-22 キヤノン株式会社 ポリヒドロキシアルカノエート合成酵素及び該酵素をコードする遺伝子
US6808910B2 (en) 2000-03-30 2004-10-26 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
ATE461273T1 (de) 2000-11-17 2010-04-15 Metabolix Inc Herstellung von polyhydroxyalkanoaten mittlerer kettenlänge aus fettsäure-biosynthesewegen
US6808907B2 (en) 2001-03-27 2004-10-26 Canon Kabushiki Kaisha Method and apparatus for producing polyhydroxyalkanoate
CA2600882C (en) 2005-03-16 2013-02-26 Metabolix, Inc. Chemically inducible expression of biosynthetic pathways
JP5551448B2 (ja) 2007-03-16 2014-07-16 ジェノマティカ・インコーポレイテッド １，４−ブタンジオールおよびその前駆体の生合成のための組成物および方法
WO2010030711A2 (en) 2008-09-10 2010-03-18 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
WO2010102217A1 (en) 2009-03-05 2010-09-10 Metabolix, Inc. Stable, fertile, high polyhydroxyalkanoate producing plants and methods of producing them
CA2754108A1 (en) 2009-03-05 2010-09-10 Metabolix, Inc. Propagation of transgenic plants
CN107384846B (zh) 2009-06-04 2021-08-10 基因组股份公司 生产1,4-丁二醇的微生物和相关方法
US20120174253A1 (en) 2009-09-15 2012-07-05 Nii Patterson Generation of high polyhydroxybutrate producing oilseeds
WO2011052718A1 (ja) 2009-10-30 2011-05-05 ダイセル化学工業株式会社 １，３－ブタンジオール生産機能を付与された遺伝子組換え微生物及びその利用
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
BR112012020132B1 (pt) 2010-02-11 2021-09-28 Cj Cheiljedang Corporation Método para produzir um acrilato de alquila inferior e 2-buteno a partir de poli-3- hidroxibutirato de biomassa geneticamente modificada
BR112014009140B1 (pt) 2011-10-25 2020-01-28 Marrone Bio Innovations Inc método para modular a infestação de uma praga
TW201410865A (zh) 2012-06-04 2014-03-16 Genomatica Inc 製造４－羥基丁酸酯、１，４－丁二醇及相關化合物之微生物及方法
IT201800003441A1 (it) * 2018-03-12 2019-09-12 Bio On Spa Poliidrossialcanoati per l’uso nella prevenzione del cancro colorettale.
CN110699391B (zh) * 2019-11-01 2023-05-30 山东省农业科学院农产品研究所 一种微波辅助碱法预处理牡丹果荚制备生物塑料聚-β-羟丁酸的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1229123A3 (de) * 1987-06-29 2004-11-03 Massachusetts Institute Of Technology Verfahren zur Herstellung von Polyester-Biopolymeren

Also Published As

Publication number Publication date
EP0870837B1 (de) 2002-11-06
JP2001178482A (ja) 2001-07-03
DE69032713T2 (de) 1999-04-08
JPH11332588A (ja) 1999-12-07
JP3964436B2 (ja) 2007-08-22
ATE227340T1 (de) 2002-11-15
ES2131489T1 (es) 1999-08-01
JP3964437B2 (ja) 2007-08-22
ES2125222T3 (es) 1999-03-01
DE69034017D1 (de) 2002-12-12
DE69032713D1 (de) 1998-11-26
ATE172497T1 (de) 1998-11-15
JP3967371B2 (ja) 2007-08-29
EP0870837A1 (de) 1998-10-14
JP2004329219A (ja) 2004-11-25
ES2131489T3 (es) 2003-05-16
DK0482077T3 (da) 1999-06-28
CA2062816C (en) 2006-09-12
CA2062816A1 (en) 1991-01-11
JP2005287517A (ja) 2005-10-20
JP3703983B2 (ja) 2005-10-05
JP2007143567A (ja) 2007-06-14
JPH05500751A (ja) 1993-02-18
JP2005278656A (ja) 2005-10-13
EP0482077A1 (de) 1992-04-29
DE69034017T2 (de) 2003-07-31
EP0482077B1 (de) 1998-10-21
WO1991000917A1 (en) 1991-01-24
JP2003189858A (ja) 2003-07-08

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