DE69032713D1 - Verfahren zur Herstellung von Polyester-Biopolymeren - Google Patents

Verfahren zur Herstellung von Polyester-Biopolymeren

Info

Publication number
DE69032713D1
DE69032713D1 DE69032713T DE69032713T DE69032713D1 DE 69032713 D1 DE69032713 D1 DE 69032713D1 DE 69032713 T DE69032713 T DE 69032713T DE 69032713 T DE69032713 T DE 69032713T DE 69032713 D1 DE69032713 D1 DE 69032713D1
Authority
DE
Germany
Prior art keywords
phb
polymers
pha
polymerase
production
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69032713T
Other languages
English (en)
Other versions
DE69032713T2 (de
Inventor
Oliver Peoples
Anthony Sinskey
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Massachusetts Institute of Technology
Original Assignee
Massachusetts Institute of Technology
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=23491962&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DE69032713(D1) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Massachusetts Institute of Technology filed Critical Massachusetts Institute of Technology
Publication of DE69032713D1 publication Critical patent/DE69032713D1/de
Application granted granted Critical
Publication of DE69032713T2 publication Critical patent/DE69032713T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

Landscapes

  • Genetics & Genomics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Biological Depolymerization Polymers (AREA)
  • Materials For Medical Uses (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
DE69032713T 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren Expired - Lifetime DE69032713T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US37815589A 1989-07-10 1989-07-10
PCT/US1990/003851 WO1991000917A1 (en) 1989-07-10 1990-07-10 Method for producing novel polyester biopolymers

Publications (2)

Publication Number Publication Date
DE69032713D1 true DE69032713D1 (de) 1998-11-26
DE69032713T2 DE69032713T2 (de) 1999-04-08

Family

ID=23491962

Family Applications (3)

Application Number Title Priority Date Filing Date
DE69034017T Expired - Lifetime DE69034017T2 (de) 1989-07-10 1990-07-10 Eine zur Herstellung von Polyhydroxybutyrat oder einem anderen Polyhydroxyalkanoat geeignete Pflanze oder pflanzliche Zelle
DE69032713T Expired - Lifetime DE69032713T2 (de) 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren
DE0870837T Pending DE870837T1 (de) 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren

Family Applications Before (1)

Application Number Title Priority Date Filing Date
DE69034017T Expired - Lifetime DE69034017T2 (de) 1989-07-10 1990-07-10 Eine zur Herstellung von Polyhydroxybutyrat oder einem anderen Polyhydroxyalkanoat geeignete Pflanze oder pflanzliche Zelle

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE0870837T Pending DE870837T1 (de) 1989-07-10 1990-07-10 Verfahren zur Herstellung von Polyester-Biopolymeren

Country Status (8)

Country Link
EP (2) EP0482077B1 (de)
JP (8) JPH05500751A (de)
AT (2) ATE227340T1 (de)
CA (1) CA2062816C (de)
DE (3) DE69034017T2 (de)
DK (1) DK0482077T3 (de)
ES (2) ES2131489T3 (de)
WO (1) WO1991000917A1 (de)

Families Citing this family (59)

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US5480794A (en) * 1987-06-29 1996-01-02 Massachusetts Institute Of Technology And Metabolix, Inc. Overproduction and purification of soluble PHA synthase
GB9108756D0 (en) * 1991-04-24 1991-06-12 Ici Plc Production of polyalkanoate in plants
GB9115245D0 (en) 1991-07-16 1991-08-28 Ici Plc Production of polyalkanoate
EP0595896B1 (de) * 1991-07-19 2005-05-18 Michigan State University Transgene pflanzen die polyhydroxyalkanoate produzieren
US5610041A (en) * 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
US5569595A (en) * 1991-09-27 1996-10-29 Center For Innovative Technology Production of poly-β-hydroxybutyrate in prokaryotic host cells
GB9223332D0 (en) * 1992-11-06 1992-12-23 Ici Plc Production of polyhydroxyalkanoate in plants
CA2127807A1 (en) * 1992-11-20 1994-06-09 John Maliyakal Transgenic cotton plants producing heterologous bioplastic
WO1995021257A1 (en) * 1994-02-03 1995-08-10 Center For Innovative Technology Improved production of poly-beta-hydroxyalkanoates in transformed prokaryotic hosts
CN1079835C (zh) * 1994-06-01 2002-02-27 普罗克特和甘保尔公司 利用空气分级作用回收聚羟基链烷酸酯的方法
CA2191713C (en) * 1994-06-01 2000-08-29 Isao Noda Process for recovering polyhydroxyalkanoates using centrifugal fractionation
US6083729A (en) * 1995-10-26 2000-07-04 Metabolix, Inc. Methods for isolating polyhydroxyalkanoates from plants
EP0870053A4 (de) * 1995-12-19 2002-09-11 Univ Minnesota Metabolisches verfahren zur herstellung von polyhydroxyalkanoat-monomer synthasen
GB9605704D0 (en) * 1996-03-19 1996-05-22 Zeneca Ltd Microorganisms and processes using them
AU2304097A (en) * 1996-04-05 1997-10-29 Kieta Holding S.A. Compositions and methods relating to drug discovery and detection and treatment of gastrointestinal diseases
US5811272A (en) * 1996-07-26 1998-09-22 Massachusetts Institute Of Technology Method for controlling molecular weight of polyhydroxyalkanoates
JP3062459B2 (ja) * 1996-08-14 2000-07-10 理化学研究所 ポリエステル重合酵素遺伝子及びポリエステルの製造方法
WO1998036078A1 (en) * 1997-02-13 1998-08-20 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units
JPH10276781A (ja) * 1997-04-01 1998-10-20 Rikagaku Kenkyusho ポリエステル重合酵素及び該酵素をコードする遺伝子
US6391611B1 (en) 1997-04-01 2002-05-21 Japan Science And Technology Corporation Polyester synthase and a gene coding for the same
EP0881293A1 (de) * 1997-05-28 1998-12-02 Eidgenössische Technische Hochschule Zürich Institut für Biotechnologie Herstellung von mittelkettigen Poly-3-Hydroxyalkanoaten in E. coli und davon abgeleiteten Monomeren
DE69838768T2 (de) 1997-09-19 2008-10-30 Metabolix, Inc., Cambridge Biologische Systeme zur Herstellung von Polyhydroxyalkanoat-Polymeren die 4-Hy droxysäure enthalten
EP1044278A1 (de) * 1998-01-05 2000-10-18 Monsanto Company Biosynthese mittelkettiger polyhydroyalkanoaten
WO1999034687A1 (en) 1998-01-07 1999-07-15 Metabolix, Inc. Animal nutrition compositions
US6586658B1 (en) 1998-03-06 2003-07-01 Metabolix, Inc. Modification of fatty acid metabolism in plants
US6103956A (en) * 1998-03-31 2000-08-15 Regents Of The University Of Minnesota Polyhydroxyalkanoate synthesis in plants
US6143952A (en) * 1998-03-31 2000-11-07 Regents Of The University Of Minnesota Modified pseudomonas oleovorans phaC1 nucleic acids encoding bispecific polyhydroxyalkanoate polymerase
DE69942060D1 (de) 1998-04-08 2010-04-08 Metabolix Inc Verfahren für die trennung und reinigung von biopolymeren
WO1999061624A2 (en) * 1998-05-22 1999-12-02 Metabolix, Inc. Polyhydroxyalkanoate biopolymer compositions
WO2000006762A1 (en) * 1998-07-30 2000-02-10 Metabolix, Inc. Production of block copolymers of polyhydroxyalkanoates in biological systems
JP2002521060A (ja) * 1998-07-30 2002-07-16 メタボリックス，インコーポレイテッド 生体高分子生成のための酵素
WO2000008198A1 (en) * 1998-08-04 2000-02-17 Metabolix, Inc. Polyhydroxyalkanoate production from polyols
AU753132B2 (en) * 1998-08-18 2002-10-10 Metabolix, Inc. Transgenic microbial polyhydroxyalkanoate producers
US6448473B1 (en) 1999-03-05 2002-09-10 Monsanto Technology Llc Multigene expression vectors for the biosynthesis of products via multienzyme biological pathways
WO2001059091A2 (en) 2000-02-11 2001-08-16 Metabolix, Inc. Multi-gene expression constructs containing modified inteins
US6875596B2 (en) 2000-03-30 2005-04-05 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
JP3848046B2 (ja) * 2000-03-30 2006-11-22 キヤノン株式会社 ポリヒドロキシアルカノエート合成酵素及び該酵素をコードする遺伝子
JP3848048B2 (ja) * 2000-03-30 2006-11-22 キヤノン株式会社 ポリヒドロキシアルカノエート合成酵素及び該酵素をコードする遺伝子
US6812013B2 (en) 2000-03-30 2004-11-02 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same
US6803220B2 (en) 2000-03-30 2004-10-12 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
JP3848047B2 (ja) 2000-03-30 2006-11-22 キヤノン株式会社 ポリヒドロキシアルカノエート合成酵素及び該酵素をコードする遺伝子
US6803219B2 (en) 2000-03-30 2004-10-12 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
US6808910B2 (en) 2000-03-30 2004-10-26 Canon Kabushiki Kaisha Polyhydroxyalkanoate synthase and gene encoding the same enzyme
ES2340915T3 (es) 2000-11-17 2010-06-11 Metabolix, Inc. Produccion de polihidroxialcanoatos de longitud media de cadena por caminos de biosintesis de acidos grasos.
US6808907B2 (en) * 2001-03-27 2004-10-26 Canon Kabushiki Kaisha Method and apparatus for producing polyhydroxyalkanoate
AU2006227634B2 (en) 2005-03-16 2010-07-08 Metabolix, Inc. Chemically inducible expression of biosynthetic pathways
CA2678946C (en) 2007-03-16 2019-02-12 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
AU2009291825B2 (en) 2008-09-10 2016-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
BRPI1012685A2 (pt) 2009-03-05 2015-09-15 Metabolix Inc método para melhorar as características de uma planta, método para propagação de plantas transgênicas, método para supertransformação de plantas transgênicas, planta trasngênica produzida pelo método, semente da planta transgênica e matéria-prima de biorefinaria
BRPI1012639A2 (pt) 2009-03-05 2015-09-15 Metabolix Inc planta e semente de planta transplastômica, combustível de biorrefinaria ou matéria-prima de energia, método para produzir uma planta transplastômica que produz mais do que 10% de pha por unidade de peso seco em suas folhas e método para produzir uma planta transplastômica que produz pha em suas folhas.
EP3392340B1 (de) 2009-06-04 2022-01-05 Genomatica, Inc. Mikroorganismen zur herstellung von 1,4-butandiol und entsprechende verfahren
CA2773707A1 (en) 2009-09-15 2011-03-24 Metabolix, Inc. Generation of high polyhydroxybutrate producing oilseeds with improved germination and seedling establishment
WO2011052718A1 (ja) 2009-10-30 2011-05-05 ダイセル化学工業株式会社 １，３－ブタンジオール生産機能を付与された遺伝子組換え微生物及びその利用
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
BR112012020299A8 (pt) 2010-02-11 2017-10-03 Metabolix Inc Processo para produção de gama-butirolactona
HUE041589T2 (hu) 2011-10-25 2019-05-28 Marrone Bio Innovations Inc Chromobacterium-formulációk, -készítmények, -metabolitok és alkalmazásuk
WO2013184602A2 (en) 2012-06-04 2013-12-12 Genomatica, Inc. Microorganisms and methods for production of 4-hydroxybutyrate, 1,4-butanediol and related compounds
IT201800003441A1 (it) * 2018-03-12 2019-09-12 Bio On Spa Poliidrossialcanoati per l’uso nella prevenzione del cancro colorettale.
CN110699391B (zh) * 2019-11-01 2023-05-30 山东省农业科学院农产品研究所 一种微波辅助碱法预处理牡丹果荚制备生物塑料聚-β-羟丁酸的方法

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP1229123A3 (de) * 1987-06-29 2004-11-03 Massachusetts Institute Of Technology Verfahren zur Herstellung von Polyester-Biopolymeren

Also Published As

Publication number Publication date
WO1991000917A1 (en) 1991-01-24
CA2062816A1 (en) 1991-01-11
JP3703983B2 (ja) 2005-10-05
JP2004329219A (ja) 2004-11-25
ES2131489T1 (es) 1999-08-01
ES2125222T3 (es) 1999-03-01
EP0482077B1 (de) 1998-10-21
ATE227340T1 (de) 2002-11-15
JP3964436B2 (ja) 2007-08-22
EP0870837B1 (de) 2002-11-06
ATE172497T1 (de) 1998-11-15
JPH05500751A (ja) 1993-02-18
DE69034017T2 (de) 2003-07-31
EP0870837A1 (de) 1998-10-14
DE69032713T2 (de) 1999-04-08
CA2062816C (en) 2006-09-12
DE69034017D1 (de) 2002-12-12
JP2005278656A (ja) 2005-10-13
JP2001178482A (ja) 2001-07-03
EP0482077A1 (de) 1992-04-29
DK0482077T3 (da) 1999-06-28
JP3967371B2 (ja) 2007-08-29
JP3964437B2 (ja) 2007-08-22
JPH11332588A (ja) 1999-12-07
DE870837T1 (de) 1999-09-16
JP2007143567A (ja) 2007-06-14
JP2003189858A (ja) 2003-07-08
ES2131489T3 (es) 2003-05-16
JP2005287517A (ja) 2005-10-20

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8310 Action for declaration of annulment
8314 Invalidation rejected