ATE323152T1 - Biologische systeme zur herstellung von polyhydroxyalkanoate polymeren die 4-hydroxysäure enthalten - Google Patents

Biologische systeme zur herstellung von polyhydroxyalkanoate polymeren die 4-hydroxysäure enthalten

Info

Publication number
ATE323152T1
ATE323152T1 AT98948384T AT98948384T ATE323152T1 AT E323152 T1 ATE323152 T1 AT E323152T1 AT 98948384 T AT98948384 T AT 98948384T AT 98948384 T AT98948384 T AT 98948384T AT E323152 T1 ATE323152 T1 AT E323152T1
Authority
AT
Austria
Prior art keywords
bacteria
production
contain
integrated
gene encoding
Prior art date
Application number
AT98948384T
Other languages
English (en)
Inventor
Gjalt W Huisman
Frank A Skraly
David P Martin
Oliver P Peoples
Original Assignee
Metabolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolix Inc filed Critical Metabolix Inc
Application granted granted Critical
Publication of ATE323152T1 publication Critical patent/ATE323152T1/de

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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08G—MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONS ONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS
    • C08G63/00—Macromolecular compounds obtained by reactions forming a carboxylic ester link in the main chain of the macromolecule
    • C08G63/02—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds
    • C08G63/06—Polyesters derived from hydroxycarboxylic acids or from polycarboxylic acids and polyhydroxy compounds derived from hydroxycarboxylic acids
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/82—Vectors or expression systems specially adapted for eukaryotic hosts for plant cells, e.g. plant artificial chromosomes (PACs)
    • C12N15/8241—Phenotypically and genetically modified plants via recombinant DNA technology
    • C12N15/8242—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits
    • C12N15/8243—Phenotypically and genetically modified plants via recombinant DNA technology with non-agronomic quality (output) traits, e.g. for industrial processing; Value added, non-agronomic traits involving biosynthetic or metabolic pathways, i.e. metabolic engineering, e.g. nicotine, caffeine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1025—Acyltransferases (2.3)
    • C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/10—Transferases (2.)
    • C12N9/1096—Transferases (2.) transferring nitrogenous groups (2.6)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cell Biology (AREA)
  • Nutrition Science (AREA)
  • Polymers & Plastics (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Biological Depolymerization Polymers (AREA)
AT98948384T 1997-09-19 1998-09-18 Biologische systeme zur herstellung von polyhydroxyalkanoate polymeren die 4-hydroxysäure enthalten ATE323152T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US5937397P 1997-09-19 1997-09-19

Publications (1)

Publication Number Publication Date
ATE323152T1 true ATE323152T1 (de) 2006-04-15

Family

ID=22022544

Family Applications (1)

Application Number Title Priority Date Filing Date
AT98948384T ATE323152T1 (de) 1997-09-19 1998-09-18 Biologische systeme zur herstellung von polyhydroxyalkanoate polymeren die 4-hydroxysäure enthalten

Country Status (8)

Country Link
US (6) US6316262B1 (de)
EP (1) EP1015565B1 (de)
JP (4) JP2001516574A (de)
AT (1) ATE323152T1 (de)
AU (1) AU725516B2 (de)
CA (1) CA2303070C (de)
DE (2) DE69838768T2 (de)
WO (1) WO1999014313A2 (de)

Families Citing this family (161)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7455999B2 (en) * 1998-01-22 2008-11-25 Metabolix, Inc. Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)
US6323010B1 (en) 1998-05-22 2001-11-27 Metabolix, Inc. Polyhydroxyalkanoate biopolymer compositions
ATE385521T1 (de) 1998-08-04 2008-02-15 Metabolix Inc Herstellung von polyhydroxyalkanoaten aus polyolen
EP1105499B1 (de) * 1998-08-18 2006-03-08 Metabolix, Inc. Transgene polyhydroxyalkanoat produzierende mikroben
EP1700908B1 (de) * 1998-08-18 2016-01-06 Metabolix, Inc. Transgene Polyhydroxyalkanoat produzierende Mikroben
DE60036863T2 (de) 1999-03-25 2008-07-31 Metabolix, Inc., Cambridge Medizinische vorrichtungen und verwendungen von polyhydroxyalkanoatpolymeren
DE60019435T2 (de) 1999-09-14 2006-02-23 Tepha, Inc., Cambridge Therapeutische anwendung von polymere die gamma-hydroxybutyrat enthalten
ES2336641T3 (es) 2000-02-11 2010-04-15 Metabolix, Inc. Constructos de expresion multigenicos que contienen inteinas modificadas.
US20020164729A1 (en) 2000-07-21 2002-11-07 Skraly Frank A. Production of polyhydroxyalkanoates from polyols
US6933404B2 (en) 2001-12-18 2005-08-23 Metabolix Inc. Methods of making intermediates from polyhydroxyalkanoates
AU2002360695A1 (en) 2001-12-19 2003-07-09 Nmt Medical, Inc. Septal occluder and associated methods
US7318833B2 (en) 2001-12-19 2008-01-15 Nmt Medical, Inc. PFO closure device with flexible thrombogenic joint and improved dislodgement resistance
AU2003210510A1 (en) * 2002-01-14 2003-07-30 Nmt Medical, Inc. Patent foramen ovale (pfo) closure method and device
AU2003220502A1 (en) 2002-03-25 2003-10-13 Nmt Medical, Inc. Patent foramen ovale (pfo) closure clips
WO2003103476A2 (en) 2002-06-05 2003-12-18 Nmt Medical, Inc. Patent foramen ovale (pfo) closure device with radial and circumferential support
AUPS318202A0 (en) * 2002-06-26 2002-07-18 Cochlear Limited Parametric fitting of a cochlear implant
ATE505559T1 (de) 2002-09-12 2011-04-15 Metabolix Inc Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege
AU2003284976A1 (en) 2002-10-25 2004-05-13 Nmt Medical, Inc. Expandable sheath tubing
EP1562653A1 (de) * 2002-11-06 2005-08-17 NMT Medical, Inc. Medizinischevorrichtungen bestehend aus veränderten formgedächtnislegierungen
US9017373B2 (en) 2002-12-09 2015-04-28 W.L. Gore & Associates, Inc. Septal closure devices
EP1591531B1 (de) 2003-01-22 2016-03-23 Showa Denko K.K. Verfahren für acylübertragungsenzymreaktionen mit acyl-coenzym a
DK1638615T3 (en) 2003-05-08 2015-01-12 Tepha Inc MEDICAL POLYHYDROXYALKANOATE TEXTILES AND FIBERS
EP2481356B1 (de) 2003-07-14 2013-09-11 W.L. Gore & Associates, Inc. Rohrförmige Verschlussvorrichtung mit Sperrsystem für persistierendes Foramen ovale (PFO)
US8480706B2 (en) 2003-07-14 2013-07-09 W.L. Gore & Associates, Inc. Tubular patent foramen ovale (PFO) closure device with catch system
US9861346B2 (en) 2003-07-14 2018-01-09 W. L. Gore & Associates, Inc. Patent foramen ovale (PFO) closure device with linearly elongating petals
US7963952B2 (en) 2003-08-19 2011-06-21 Wright Jr John A Expandable sheath tubing
US8071342B2 (en) * 2003-10-15 2011-12-06 Newlight Technologies, Llc Process for the treatment of methane emissions
US8735113B2 (en) 2003-10-15 2014-05-27 Newlight Technologies, Llc Methods and systems for production of polyhydroxyalkanoate
US7579176B2 (en) 2003-10-15 2009-08-25 Newlight Technologies, Llc Method for the production of polyhydroxyalkanoic acid
US7745197B1 (en) 2003-10-15 2010-06-29 Newlight Technologies, Llc Process for the utilization of ruminant animal methane emissions
US20050273119A1 (en) * 2003-12-09 2005-12-08 Nmt Medical, Inc. Double spiral patent foramen ovale closure clamp
US7871419B2 (en) 2004-03-03 2011-01-18 Nmt Medical, Inc. Delivery/recovery system for septal occluder
US20050267524A1 (en) 2004-04-09 2005-12-01 Nmt Medical, Inc. Split ends closure device
US8361110B2 (en) 2004-04-26 2013-01-29 W.L. Gore & Associates, Inc. Heart-shaped PFO closure device
US8308760B2 (en) 2004-05-06 2012-11-13 W.L. Gore & Associates, Inc. Delivery systems and methods for PFO closure device with two anchors
US7842053B2 (en) 2004-05-06 2010-11-30 Nmt Medical, Inc. Double coil occluder
CA2563298A1 (en) 2004-05-07 2005-11-24 Nmt Medical, Inc. Catching mechanisms for tubular septal occluder
JP4720114B2 (ja) * 2004-05-20 2011-07-13 三菱化学株式会社 オキザロ酢酸またはオキザロ酢酸誘導体の製造方法
PT1778305E (pt) 2004-08-03 2010-07-27 Tepha Inc Suturas de poli-hidroxialcanoato que n†o se enrolam
WO2006036837A2 (en) 2004-09-24 2006-04-06 Nmt Medical, Inc. Occluder device double securement system for delivery/recovery of such occluder device
JP2008532553A (ja) * 2005-03-16 2008-08-21 メタボリックス， インコーポレイテッド 生合成経路の化学的に誘導可能な発現
US8277480B2 (en) 2005-03-18 2012-10-02 W.L. Gore & Associates, Inc. Catch member for PFO occluder
KR100979694B1 (ko) 2005-05-24 2010-09-02 한국과학기술원 폴리락테이트 또는 그 공중합체 생성능을 가지는 세포 또는식물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
CA2627285A1 (en) * 2005-10-24 2007-10-25 Nmt Medical, Inc. Radiopaque bioabsorbable occluder
EP1962695A1 (de) * 2005-12-22 2008-09-03 NMT Medical, Inc. Fangglieder für verschlussvorrichtungen
US8016883B2 (en) * 2006-02-07 2011-09-13 Tepha, Inc. Methods and devices for rotator cuff repair
US9592325B2 (en) * 2006-02-07 2017-03-14 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
US8979921B2 (en) * 2006-02-07 2015-03-17 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
US7618448B2 (en) * 2006-02-07 2009-11-17 Tepha, Inc. Polymeric, degradable drug-eluting stents and coatings
CA2647505C (en) 2006-03-31 2014-07-29 Nmt Medical, Inc. Deformable flap catch mechanism for occluder device
US8870913B2 (en) 2006-03-31 2014-10-28 W.L. Gore & Associates, Inc. Catch system with locking cap for patent foramen ovale (PFO) occluder
US8551135B2 (en) 2006-03-31 2013-10-08 W.L. Gore & Associates, Inc. Screw catch mechanism for PFO occluder and method of use
US9089627B2 (en) 2006-07-11 2015-07-28 Abbott Cardiovascular Systems Inc. Stent fabricated from polymer composite toughened by a dispersed phase
JP5468779B2 (ja) * 2006-07-21 2014-04-09 株式会社カネカ 遺伝子置換微生物およびそれを用いたポリエステルの製造方法
US20080082083A1 (en) * 2006-09-28 2008-04-03 Forde Sean T Perforated expandable implant recovery sheath
EP4047033A1 (de) * 2006-11-21 2022-08-24 LG Chem, Ltd. Copolymer mit einer 4-hydroxybutyrateinheit und einer laktateinheit und verfahren zu seiner herstellung
US7943683B2 (en) 2006-12-01 2011-05-17 Tepha, Inc. Medical devices containing oriented films of poly-4-hydroxybutyrate and copolymers
JP2010517638A (ja) * 2007-02-02 2010-05-27 トアニエ， インコーポレイテッド 腱および靱帯を修復するシステムおよび方法
TWI488964B (zh) 2007-03-16 2015-06-21 Genomatica Inc 用於１，４丁二醇及其前驅物之生物合成的組合物及方法
US9005242B2 (en) 2007-04-05 2015-04-14 W.L. Gore & Associates, Inc. Septal closure device with centering mechanism
US9138562B2 (en) 2007-04-18 2015-09-22 W.L. Gore & Associates, Inc. Flexible catheter system
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
US8581040B2 (en) 2007-08-30 2013-11-12 Plant Sensory Systems, Llc Methods of producing GABA
US8581041B2 (en) 2007-08-30 2013-11-12 Plant Sensory Systems, Llc Methods of producing GABA
BRPI0816083A2 (pt) * 2007-08-30 2017-05-16 Plant Sensory System Llc métodos alternativos para a biossíntese de gaba
TWI356705B (en) * 2007-10-25 2012-01-21 Internat Chlorella Co Ltd Extracts from chlorella sorokiniana
WO2009078973A2 (en) * 2007-12-13 2009-06-25 Glycos Biotechnologies, Incorporated Microbial conversion of oils and fatty acids to high-value chemicals
WO2009085823A1 (en) * 2007-12-19 2009-07-09 Tepha, Inc. Medical devices containing melt-blown non-wovens of poly-r-hydroxybutyrate and copolymers
KR20090078925A (ko) * 2008-01-16 2009-07-21 주식회사 엘지화학 폴리락테이트 또는 그 공중합체 생성능을 가지는 재조합미생물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
US20130165967A1 (en) 2008-03-07 2013-06-27 W.L. Gore & Associates, Inc. Heart occlusion devices
US20090253154A1 (en) * 2008-04-02 2009-10-08 Immunosciences Lab., Inc. Blood and saliva test for detection of delayed food allergy and intolerance against modified foods
US8487159B2 (en) * 2008-04-28 2013-07-16 Metabolix, Inc. Production of polyhydroxybutyrate in switchgrass
US20110190513A1 (en) * 2008-07-08 2011-08-04 Lynch Michael D Methods, compositions and systems for biosynthetic bio-production of 1,4-butanediol
AU2009291825B2 (en) 2008-09-10 2016-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
KR101886012B1 (ko) 2008-12-12 2018-08-06 씨제이제일제당 (주) 폴리（5ｈｖ）및 5 탄소 화학물질의 생산을 위한 녹색 공정 및 조성물
US9023622B2 (en) * 2009-02-10 2015-05-05 Kyowa Hakko Bio Co., Ltd. Method for producing L-amino acid using a microorganism with decreased aspartate aminotransferase activity
WO2010102220A1 (en) 2009-03-05 2010-09-10 Metabolix, Inc. Propagation of transgenic plants
MY187676A (en) 2009-06-04 2021-10-08 Genomatica Inc Microorganisms for the production of 1,4-butanediol and related methods
BRPI1010582B1 (pt) 2009-06-04 2018-11-06 Genomatica Inc processo de separação de componentes de um caldo de fermentação
US8956389B2 (en) 2009-06-22 2015-02-17 W. L. Gore & Associates, Inc. Sealing device and delivery system
US20120029556A1 (en) 2009-06-22 2012-02-02 Masters Steven J Sealing device and delivery system
WO2011031566A1 (en) 2009-08-27 2011-03-17 Newlight Technologies, Llc Process for the production of polyhydroxyalkanoates
CA2773703A1 (en) 2009-09-15 2011-03-24 Metabolix, Inc. Generation of high polyhydroxybutrate producing oilseeds
CA2777459A1 (en) * 2009-10-13 2011-04-21 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol, 4-hydroxybutanal, 4-hydroxybutyryl-coa, putrescine and related compounds, and methods related thereto
WO2011063363A2 (en) * 2009-11-20 2011-05-26 Opx Biotechnologies, Inc. Production of an organic acid and/or related chemicals
WO2011066076A1 (en) 2009-11-25 2011-06-03 Genomatica, Inc. Microorganisms and methods for the coproduction of 1,4-butanediol and gamma-butyrolactone
US20110166598A1 (en) * 2009-12-02 2011-07-07 Entrigue Surgical, Inc. Devices and methods for tongue stabilization
MX2012009134A (es) 2010-02-11 2012-11-30 Metabolix Inc Proceso para producir componente monomerico de biomasa de polihidroxialcanoato geneticamente modificado.
US8048661B2 (en) 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8637286B2 (en) 2010-02-23 2014-01-28 Genomatica, Inc. Methods for increasing product yields
GB2478588A (en) * 2010-03-12 2011-09-14 G5 Internat Holdings Pte Ltd Microbial production of polyhydroxyalkanoates (PHAs) using culture medium containing hydrogen
PT2558133T (pt) 2010-03-26 2020-04-23 Tepha Inc Revestimentos para o fabrico e aplicação de dispositivos médicos de polihidroxialcanqato
EP2582866B1 (de) 2010-06-15 2014-09-17 Tepha, Inc. Medizinprodukte mit trockengesponnen vliesstoffe aus poly-4-hydroxybutyrat und copolymere
US9511169B2 (en) 2010-06-15 2016-12-06 Tepha, Inc. Medical devices containing dry spun non-wovens of poly-4-hydroxybutyrate and copolymers with anisotropic properties
EP2425865A1 (de) 2010-08-06 2012-03-07 Aesculap AG Medizinisches Gewinde mit Polyhydroxyalkanoatbeschichtung
WO2012037324A2 (en) 2010-09-15 2012-03-22 Metabolix, Inc. Increasing carbon flow for polyhydroxybutyrate production in biomass crops
WO2012064526A1 (en) 2010-11-09 2012-05-18 Tepha, Inc. Drug eluting cochlear implants
US8956835B2 (en) 2010-11-24 2015-02-17 Suny Research Foundation Methods for producing polyhydroxyalkanoates from biodiesel-glycerol
CA2825624C (en) 2011-01-27 2020-01-14 Osa Holdings, Inc. Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
WO2012122343A2 (en) 2011-03-08 2012-09-13 Newlight Technologies, Llc Polyhydroxyalkanoate production method
BR112013027641A2 (pt) * 2011-04-29 2016-11-29 Metabolix Inc processo verde para produzir poli-hidroxialcanoatos e produtos químicos com o uso de uma matéria-prima renovável
EP2702091B1 (de) 2011-04-29 2019-02-13 CJ CheilJedang Corporation Verfahren zur latexherstellung durch schmelzemulgierung
WO2012170793A1 (en) 2011-06-08 2012-12-13 Metabolix, Inc. Biorefinery process for thf production
DK2738247T3 (en) 2011-07-29 2017-01-09 Mitsui Chemicals Inc MICROORGANISM WITH CARBON Dioxide FIXING CYCLE INTRODUCED THERE
WO2013023140A1 (en) 2011-08-10 2013-02-14 Metabolix, Inc. Post process purification for gamma-butyrolactone production
US9770232B2 (en) 2011-08-12 2017-09-26 W. L. Gore & Associates, Inc. Heart occlusion devices
EP2754717A4 (de) * 2011-09-05 2015-08-05 Riken Verfahren zur herstellung von polyhydroxyalkanoat mit langer hauptkettenstruktur
WO2013049161A1 (en) 2011-09-27 2013-04-04 Tepha, Inc. Controlled hydrolysis of poly-4-hydroxybutyrate and copolymers
PH12014500549B1 (en) 2011-10-25 2018-09-14 Marrone Bio Innovations Inc Chromobacterium formulations, compositions, metabolites and their uses
BR112014010448A2 (pt) 2011-11-02 2017-04-18 Genomatica Inc microorganismos e métodos para a produção de caprolactona
US12060597B2 (en) 2011-12-02 2024-08-13 Newlight Technologies, Inc. Polyhydroxyalkanoate production methods and systems for same
US20200347417A1 (en) 2012-03-29 2020-11-05 Newlight Technologies, Inc Polyhydroxyalkanoate production methods and materials and microorganisms used in same
US9085784B1 (en) 2012-03-29 2015-07-21 Newlight Technologies, Llc Polyhydroxyalkanoate production methods and materials and microorganisms used in same
HK1206787A1 (en) * 2012-04-11 2016-01-15 Helmholtz-Zentrum Fuer Infektionsforschung Gmbh Pha-producing genetically engineered
ES2734126T3 (es) 2012-05-21 2019-12-04 Tepha Inc Composiciones biocerámicas reabsorbibles de poli-4-hidroxibutirato y copolímeros
TW201410865A (zh) 2012-06-04 2014-03-16 Genomatica Inc 製造４－羥基丁酸酯、１，４－丁二醇及相關化合物之微生物及方法
US9850192B2 (en) 2012-06-08 2017-12-26 Cj Cheiljedang Corporation Renewable acrylic acid production and products made therefrom
WO2014028943A1 (en) 2012-08-17 2014-02-20 Metabolix, Inc. Biobased rubber modifiers for polymer blends
ES2747230T3 (es) 2012-10-10 2020-03-10 Cj Cheiljedang Corp Método de elaboración de copolímeros de polihidroxialcanoato (3HB-co-4HB)
EP2961738B1 (de) 2012-11-14 2019-12-25 CJ CheilJedang Corporation Herstellung von salzen von 4-hydroxybutyrate mittels biobasierter rohstoffe
WO2014113268A1 (en) 2013-01-15 2014-07-24 Tepha, Inc. Implants for soft and hard tissue regeneration
US10828019B2 (en) 2013-01-18 2020-11-10 W.L. Gore & Associates, Inc. Sealing device and delivery system
US9828618B2 (en) 2013-01-24 2017-11-28 Mitsui Chemicals, Inc. Microorganism having carbon dioxide fixation cycle introduced thereinto
WO2014127053A2 (en) 2013-02-13 2014-08-21 Metabolix, Inc. Process for ultra pure chemical production from biobased raw starting materials
US10201640B2 (en) 2013-03-13 2019-02-12 Tepha, Inc. Ultrafine electrospun fibers of poly-4-hydroxybutyrate and copolymers thereof
EP3036277B1 (de) 2013-08-20 2021-05-26 Tepha, Inc. Geschlossenzellige schaumstoffe mit poly-4-hydroxybutyrat und copolymere davon
US9687585B2 (en) 2013-08-20 2017-06-27 Tepha, Inc. Thermoformed poly-4-hydroxybutyrate medical implants
US9302029B2 (en) 2013-10-31 2016-04-05 Tepha, Inc. Pultrusion of poly-4-hydroxybutyrate and copolymers thereof
EP3065789B1 (de) 2013-11-05 2018-10-24 Tepha, Inc. Zusammensetzungen und vorrichtungen aus poly-4-hydroxybutyrat
US10485535B2 (en) 2013-12-19 2019-11-26 Tornier, Inc. High-strength bioabsorbable suture
ES2834498T3 (es) 2013-12-26 2021-06-17 Tepha Inc Implantes médicos que incluyen laminados de poli-4-hidroxibutirato y copolímeros del mismo
ES2685963T3 (es) 2014-03-18 2018-10-15 Tepha, Inc. Bandas de microfibras de poli-4-hidroxibutirato y sus copolímeros producidas por hilado centrífugo
CA2947141C (en) 2014-04-30 2019-01-15 Tepha, Inc. Three-dimensional resorbable implants for tissue reinforcement and hernia repair
EP3142716B1 (de) 2014-05-16 2018-04-25 Tepha, Inc. Medizinische vorrichtungen mit trockengesponnenen vliesstoffen aus poly-4-hydroxybutyrat und copolymeren mit anisotropen eigenschaften
US9808230B2 (en) 2014-06-06 2017-11-07 W. L. Gore & Associates, Inc. Sealing device and delivery system
WO2016025329A1 (en) 2014-08-15 2016-02-18 Tepha, Inc. Self-retaining sutures of poly-4-hydroxybutyrate and copolymers thereof
ES2661648T3 (es) 2014-08-20 2018-04-02 Tepha, Inc. Implantes médicos de poli-4-hidroxibutirato termoformados
ES2802383T3 (es) 2014-09-22 2021-01-19 Tepha Inc Implantes de P4HB orientados que contienen agentes antimicrobianos
WO2016053741A1 (en) 2014-10-01 2016-04-07 Cryosa, Llc Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues
US10626521B2 (en) 2014-12-11 2020-04-21 Tepha, Inc. Methods of manufacturing mesh sutures from poly-4-hydroxybutyrate and copolymers thereof
EP3230500B1 (de) 2014-12-11 2025-06-18 Tepha, Inc. Verfahren zum orientieren von multifilamentgarn und monofilamente aus poly-4-hydroxybutyrat und copolymere davon
EP3365427B1 (de) 2015-10-23 2020-08-19 Metabolic Explorer Modifizierter mikroorganismus zur assimilierung von levulinsäure
EP3400100B1 (de) 2016-01-06 2020-09-23 Archer Daniels Midland Company Verfahren zur herstellung von 1,3-butandiol und zur optionalen weiteren herstellung von (r)-3-hydroxybutyl (r)-3-hydroxybutyrat
KR101774431B1 (ko) * 2016-01-28 2017-09-05 한국과학기술원 자일로즈로부터 폴리(락테이트-co-글라이콜레이트) 또는 그 공중합체 생산능을 가지는 재조합 미생물 및 이를 이용한 폴리(락테이트-co-글라이콜레이트) 또는 그 공중합체의 제조방법
WO2018217574A1 (en) 2017-05-25 2018-11-29 Tepha, Inc. Continuous formation of tubes of poly-4-hydroxybutyrate and copolymers thereof
CN109112151B (zh) * 2017-06-23 2021-10-29 北京蓝晶微生物科技有限公司 一种精细调控共聚物中4-羟基丁酸组成比例的基因盒及其应用
CA3074733C (en) 2017-09-06 2022-06-21 Tepha, Inc. Calendered surgical meshes comprising polyhydroxyalkanoates
EP3720514B1 (de) 2017-12-04 2022-04-13 Tepha, Inc. Vakuummembran-thermogeformte medizinische poly-4-hydroxybutyrat-implantate
EP3802062B1 (de) 2018-06-11 2024-09-18 Tepha, Inc. Verfahren zum 3d-drucken von poly-4-hydroxybutyrat
ES2956815T3 (es) 2018-10-29 2023-12-28 Tepha Inc Procedimientos de fabricación de suturas de malla a partir de poli-4-hidroxibutirato y sus copolímeros
TWI827804B (zh) * 2019-03-06 2024-01-01 日商三菱商事生命科學股份有限公司 蕈菌絲體之製造方法、含有蕈菌絲體的組成物、以及使用了蕈菌絲體之食品材料
WO2020251932A1 (en) 2019-06-10 2020-12-17 Yield10 Bioscience, Inc. Transgenic land plants that express a polyhydroxyalkanoate synthase seed specifically with cytosolic localization
CA3168812A1 (en) 2020-02-19 2021-08-26 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
FR3109290B1 (fr) 2020-04-17 2025-04-11 Ph Tech Dispositif médical comprenant une matrice biologique acellulaire et au moins un polymère
FR3110077B1 (fr) 2020-05-12 2024-12-06 Ph Tech Procédé de fabrication d’un dispositif médical en trois dimensions et dispositif médical obtenu
FR3113371A1 (fr) 2020-08-12 2022-02-18 Ph Tech Dispositif médical comprenant un assemblage d’éléments de matrices biologiques acellulaires et au moins un polymère
JP2024510182A (ja) 2021-03-11 2024-03-06 テファ， インコーポレイテッド 乳房再建インプラント
CN113832084B (zh) * 2021-09-29 2024-01-05 北京化工大学 一种生产聚羟基脂肪酸酯的溶藻弧菌及其应用
AU2022424121A1 (en) 2021-12-30 2024-06-20 Cryosa, Inc. Systems and methods for treatment of obstructive sleep apnea
WO2024072953A1 (en) * 2022-09-30 2024-04-04 Kimberly-Clark Worldwide, Inc. In vitro bioproduction of specific chain length poly(hydroxyalkanoate) monomers
FR3165166A1 (fr) 2024-08-05 2026-02-06 Ph Tech Utilisation de l’Éther de dipropylène glycol monométhylique pour purifier un biomatériau

Family Cites Families (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS575693A (en) 1980-06-13 1982-01-12 Ajinomoto Co Inc Production of l-arginine through fermentation process
IE50442B1 (en) * 1980-11-21 1986-04-16 Loctite Corp Two part adhesive composition
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
US5245023A (en) 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US4876331A (en) 1987-08-18 1989-10-24 Mitsubishi Kasei Corporation Copolyester and process for producing the same
US4876831A (en) * 1988-03-14 1989-10-31 Runyon John F Folding modular building structure
US5004664A (en) 1989-02-27 1991-04-02 Xerox Corporation Toner and developer compositions containing biodegradable semicrystalline polyesters
US5371002A (en) * 1989-06-07 1994-12-06 James Madison University Method of production of poly-beta-hydroxyalkanoate copolymers
WO1991000917A1 (en) 1989-07-10 1991-01-24 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
IE893328A1 (en) 1989-10-16 1991-04-24 Mcdaid Denis Telephone lock
GB9108756D0 (en) 1991-04-24 1991-06-12 Ici Plc Production of polyalkanoate in plants
US5286842A (en) 1991-07-01 1994-02-15 Mitsubishi Kasei Corporation Process for producing a biodegradable polymer
GB9115245D0 (en) 1991-07-16 1991-08-28 Ici Plc Production of polyalkanoate
US5610041A (en) 1991-07-19 1997-03-11 Board Of Trustees Operating Michigan State University Processes for producing polyhydroxybutyrate and related polyhydroxyalkanoates in the plastids of higher plants
AU671953B2 (en) 1991-07-19 1996-09-19 Michigan State University Transgenic plants producing polyhydroxyalkanoates
FR2680178B1 (fr) 1991-08-07 1994-10-14 Ajinomoto Kk Procede pour produire l'acide l-glutamique par fermentation.
JP2777757B2 (ja) 1991-09-17 1998-07-23 鐘淵化学工業株式会社 共重合体およびその製造方法
GB9223332D0 (en) * 1992-11-06 1992-12-23 Ici Plc Production of polyhydroxyalkanoate in plants
AU5676394A (en) 1992-11-20 1994-06-22 Agracetus, Inc. Transgenic cotton plants producing heterologous bioplastic
JP3263710B2 (ja) 1992-12-11 2002-03-11 高砂香料工業株式会社 生分解性光学活性ポリマー及びその製造方法
IL108947A0 (en) 1993-03-12 1994-06-24 Osteopharm Ltd Bone stimulating factor
US6849427B1 (en) 1993-03-12 2005-02-01 Immulogic Pharmaceutical Corp. Nucleic acids encoding a house dust mite allergen, Der p VII, and uses therefor
JP3241505B2 (ja) 1993-08-11 2001-12-25 高砂香料工業株式会社 生分解性光学活性コポリマー及びその製造方法
WO1995020615A1 (en) 1994-01-28 1995-08-03 The Procter & Gamble Company Biodegradable copolymers and plastic articles comprising biodegradable copolymers of 3-hydroxyhexanoate
ID23491A (id) 1994-01-28 1995-09-07 Procter & Gamble Kopolimer-kopolimer yang dapat dibiodegradasi dan baha-bahan plastik yang terdiri dari kopolimer-kopolimer yang dapat dibiodegradasi
CA2125313A1 (en) * 1994-06-07 1995-12-08 Gerald E. O'grady Method and apparatus for producing electrical energy within the body of a ruminant
US5563239A (en) 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
BE1008983A6 (fr) 1994-12-30 1996-10-01 Faco Sa Bigoudi.
US5763270A (en) 1995-06-07 1998-06-09 Genemedicine, Inc. Plasmid for delivery of nucleic acids to cells and methods of use
GB9602796D0 (en) 1996-02-12 1996-04-10 Innes John Centre Innov Ltd Genetic control of plant growth and development
AU6169498A (en) * 1997-02-13 1998-09-08 James Madison University Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units

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US6689589B2 (en) 2004-02-10
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US20100093043A1 (en) 2010-04-15
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US7229804B2 (en) 2007-06-12
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