ATE505559T1 - Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege - Google Patents

Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege

Info

Publication number
ATE505559T1
ATE505559T1 AT03749656T AT03749656T ATE505559T1 AT E505559 T1 ATE505559 T1 AT E505559T1 AT 03749656 T AT03749656 T AT 03749656T AT 03749656 T AT03749656 T AT 03749656T AT E505559 T1 ATE505559 T1 AT E505559T1
Authority
AT
Austria
Prior art keywords
coa
organism
aldehyde dehydrogenase
dependent aldehyde
pha
Prior art date
Application number
AT03749656T
Other languages
English (en)
Inventor
Frank Skraly
Original Assignee
Metabolix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Metabolix Inc filed Critical Metabolix Inc
Application granted granted Critical
Publication of ATE505559T1 publication Critical patent/ATE505559T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • Plant Pathology (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
AT03749656T 2002-09-12 2003-09-12 Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege ATE505559T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US41008702P 2002-09-12 2002-09-12
PCT/US2003/028842 WO2004024876A2 (en) 2002-09-12 2003-09-12 Polyhydroxyalkanoate production by coenzyme a-dependent aldehyde dehydrogenase pathways

Publications (1)

Publication Number Publication Date
ATE505559T1 true ATE505559T1 (de) 2011-04-15

Family

ID=31994056

Family Applications (1)

Application Number Title Priority Date Filing Date
AT03749656T ATE505559T1 (de) 2002-09-12 2003-09-12 Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege

Country Status (8)

Country Link
US (1) US8071355B2 (de)
EP (2) EP2365088B1 (de)
JP (2) JP4628103B2 (de)
AT (1) ATE505559T1 (de)
AU (1) AU2003267185A1 (de)
DE (2) DE60336757D1 (de)
ES (1) ES2395053T3 (de)
WO (1) WO2004024876A2 (de)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
KR100979694B1 (ko) 2005-05-24 2010-09-02 한국과학기술원 폴리락테이트 또는 그 공중합체 생성능을 가지는 세포 또는식물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
AU2008229076B2 (en) 2007-03-16 2014-05-15 Genomatica, Inc. Compositions and methods for the biosynthesis of 1,4-butanediol and its precursors
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
CN102164986B (zh) * 2008-06-24 2013-12-25 Lg化学株式会社 用具有提高聚乳酸酯及其共聚物生产能力的微生物突变体制备聚乳酸酯及其共聚物的方法
AU2009291825B2 (en) * 2008-09-10 2016-05-05 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol
WO2010057022A1 (en) * 2008-11-14 2010-05-20 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
CN102317437B (zh) 2008-12-12 2013-08-21 麦特波力克斯公司 用于制备聚(5-羟基戊酸)和5碳化合物的绿色工艺和组合物
KR101293886B1 (ko) 2009-02-05 2013-08-07 주식회사 엘지화학 폴리락틱산 또는 폴리락틱산 공중합체 생성능을 지닌 재조합 랄스토니아 유트로파 및 이것을 이용하여 폴리락틱산 또는 폴리락틱산 공중합체를 제조하는 방법
VN29801A1 (de) 2009-06-04 2012-05-25
VN29235A1 (de) * 2009-06-04 2012-03-26
CN102762735B (zh) * 2009-10-13 2016-08-03 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
FR2964014B1 (fr) * 2010-08-31 2013-04-05 Ifremer Nucleus enrobe d'un revetement filmogene aux proprietes antibacteriennes et cicatrisantes et procede d'obtention.
FR2968506B1 (fr) * 2010-12-14 2013-02-08 Ifremer Nucleus recouvert de pha
CN102212501B (zh) * 2011-03-31 2013-06-12 山东大学 一种重组大肠杆菌及应用其以单一碳源生产phbv的方法
WO2012149162A2 (en) * 2011-04-29 2012-11-01 Metabolix, Inc. Green process for producing polyhydroxyalkanoates and chemicals using a renewable feedstock
CA2845681A1 (en) 2011-08-19 2013-02-28 Genomatica, Inc. Microorganisms and methods for producing 2,4-pentadienoate, butadiene, propylene, 1,3-butanediol and related alcohols
EP2773767A4 (de) 2011-11-02 2015-08-05 Genomatica Inc Mikroorganismen und verfahren zur herstellung von caprolacton
CN104685058B (zh) 2012-06-04 2020-07-07 基因组股份公司 制造4-羟基丁酸酯、1，4-丁二醇和相关化合物的微生物和方法
CA2888197C (en) 2012-10-15 2023-03-07 Genomatica, Inc. Microorganisms and methods for production of specific length fatty alcohols and related compounds
EP2971021A4 (de) 2013-03-15 2016-12-21 Genomatica Inc Mikroorganismen und verfahren zur herstellung von butadien und verwandten verbindungen mittels formatassimilation
EP3074504A4 (de) 2013-11-25 2017-05-03 Genomatica, Inc. Verfahren zur verbesserung der mikrobiellen herstellung von fettalkoholen mit bestimmter länge in gegenwart von methanol
WO2016007365A1 (en) 2014-07-11 2016-01-14 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-coa
DK3194604T3 (da) 2014-09-18 2020-05-25 Genomatica Inc Ikke-naturlig mikrobielle organismer med forbedret energisk effektivitet
US10941454B2 (en) 2015-05-30 2021-03-09 Genomatica, Inc. Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and crotyl alcohol dehydratases and methods for making and using them
US11059769B2 (en) 2017-10-26 2021-07-13 Noroo Ic Co., Ltd. Production and separation of 3-hydroxypropionic acid
US11566250B2 (en) 2017-10-26 2023-01-31 Noroo Ic Co., Ltd. Production and separation of 3-hydroxypropionic acid
WO2021085120A1 (ja) * 2019-10-31 2021-05-06 株式会社カネカ ポリヒドロキシアルカン酸の製造方法およびその利用

Family Cites Families (19)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4477654A (en) 1981-07-07 1984-10-16 Imperial Chemical Industries Plc 3-Hydroxybutyrate polymers
EP0145233B2 (de) 1983-11-23 1991-11-06 Imperial Chemical Industries Plc Trennungsverfahrenfür ein 3-hydroxybutyrat-Polymer
US5480794A (en) 1987-06-29 1996-01-02 Massachusetts Institute Of Technology And Metabolix, Inc. Overproduction and purification of soluble PHA synthase
US5250430A (en) 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
US5229279A (en) 1987-06-29 1993-07-20 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5245023A (en) 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
GB9325952D0 (en) * 1993-12-20 1994-02-23 Zeneca Ltd Process for preparing films and coatings
PL181098B1 (pl) 1994-01-28 2001-05-31 Procter & Gamble Wyrób absorbujący i kopolimer ulegający biodegradacji
ZA95627B (en) 1994-01-28 1995-10-05 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers
FR2719012B1 (fr) 1994-04-22 1996-07-12 Pomagalski Sa Pince débrayable d'un véhicule tracté par câble.
US5563239A (en) 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
AU2324097A (en) * 1997-03-03 1998-09-22 Monsanto Company Methods for the biosynthesis of polyesters
WO1999014313A2 (en) 1997-09-19 1999-03-25 Metabolix, Inc. Biological systems for manufacture of polyhydroxylalkanoate polymers containing 4-hydroxyacids
US7455999B2 (en) 1998-01-22 2008-11-25 Metabolix, Inc. Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)
DE69938105T2 (de) 1998-08-04 2009-01-29 Metabolix, Inc., Cambridge Herstellung von polyhydroxyalkanoaten aus polyolen
US6593116B1 (en) * 1998-08-18 2003-07-15 Metabolix, Inc. Transgenic microbial polyhydroxyalkanoate producers
PT1163019E (pt) * 1999-03-25 2007-12-06 Metabolix Inc Dispositivos médicos e aplicações de polímeros de poli-hidroxialcanoato
DE60120415T2 (de) 2000-07-21 2007-01-04 Metabolix, Inc., Cambridge Herstellung von polyhydroxyalkanoaten aus polyolen
AU2002225827A1 (en) * 2000-10-27 2002-05-06 Metabolix, Inc. Compositions comprising low molecular weight polyhydroxyalkanoates and methods employing same

Also Published As

Publication number Publication date
EP2365088A3 (de) 2012-01-11
EP1581619A4 (de) 2007-02-14
WO2004024876A3 (en) 2006-05-26
EP2365088B1 (de) 2015-05-27
EP2365088A2 (de) 2011-09-14
US20040106176A1 (en) 2004-06-03
ES2395053T3 (es) 2015-10-08
AU2003267185A1 (en) 2004-04-30
ES2395053T1 (es) 2013-02-07
US8071355B2 (en) 2011-12-06
EP1581619A2 (de) 2005-10-05
DE10075400T8 (de) 2013-04-25
JP2010268797A (ja) 2010-12-02
DE10075400T1 (de) 2012-10-11
WO2004024876A2 (en) 2004-03-25
AU2003267185A8 (en) 2004-04-30
JP2006507811A (ja) 2006-03-09
DE60336757D1 (de) 2011-05-26
JP4628103B2 (ja) 2011-02-09
EP1581619B1 (de) 2011-04-13

Similar Documents

Publication Publication Date Title
ES2395053T3 (es) Producción de polihidroxialcanoato mediante las vías de la aldehído deshidrogenasa dependiente de la coenzima A
KR101042242B1 (ko) 1,4-부탄디올 생성능을 가지는 변이체 및 이를 이용한1,4-부탄디올의 제조방법
JP3967812B2 (ja) ピルビン酸カルボキシラーゼ遺伝子組み換え菌体による有機酸の製造法
York et al. Ralstonia eutropha H16 encodes two and possibly three intracellular poly [d-(−)-3-hydroxybutyrate] depolymerase genes
AU2013317782B2 (en) Compositions and methods for producing chemicals and derivatives thereof
ATE385521T1 (de) Herstellung von polyhydroxyalkanoaten aus polyolen
JP2019513007A (ja) ナノポアシーケンシングのためのポリメラーゼ−鋳型複合体
KR20070096348A (ko) 1,4―ｂｕｔａｎｅｄｉｏｌ〔１，４―ＢＤＯ〕생성능을가지는 변이체 및 이를 이용한 １，４―ＢＤＯ의 제조방법
JP4264819B2 (ja) 生分解性ポリエステルの製造方法
ES2917190T3 (es) ADN-polimerasas marinas
Takehara et al. Draft genome sequence of the nylon oligomer-degrading bacterium Arthrobacter sp. strain KI72
WO2006033333A1 (ja) アルドン酸類の製造方法およびアルドース脱水素酵素
JP2005060447A (ja) ポリアミド樹脂
Genser et al. Molecular cloning, sequencing and expression in Escherichia coli of the poly (3-hydroxyalkanoate) synthesis genes from Alcaligenes latus DSM1124
AU2018382619B2 (en) DNA polymerases
CN109536466B (zh) 醛脱氢酶及其基因、重组菌构建及其在呋喃羧酸合成中的应用
Prangishvili et al. Nucleotide sequence of the gene for a 74 kDa DNA polymerase from the archaeon Sulfolobus solfataricus.
CA2408847A1 (en) Cng3b: a novel cyclic nucleotide-gated cation channel
JP2007125030A (ja) ピルビン酸カルボキシラーゼ遺伝子組み換え菌体による有機酸の製造法
Yuliastri et al. Cloning of acetyl-CoA acetyltransferase gene from Halomonas elongata BK-AG18 and in silico analysis of its gene product
CN110577961B (zh) 一种热稳定性苹果酸脱氢酶基因的构建方法、编码蛋白及其应用
Yaoi et al. Roles of Arg231 and Tyr284 of Thermus thermophilus isocitrate dehydrogenase in the coenzyme specificity
Solaiman et al. Synthesis of poly (hydroxyalkanoates) by Escherichia coli expressing mutated and chimeric PHA synthase genes
JPH1132772A (ja) 耐熱性リボヌクレアーゼｈ及びそれをコードするｄｎａ
KR20230098486A (ko) 포스포에놀피루브산 카복실화효소를 코딩하는 유전자의 5'utr 변이 서열 및 이의 용도

Legal Events

Date Code Title Description
RER Ceased as to paragraph 5 lit. 3 law introducing patent treaties