DE10075400T8 - Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden - Google Patents

Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden Download PDF

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Publication number
DE10075400T8
DE10075400T8 DE10075400T DE10075400T DE10075400T8 DE 10075400 T8 DE10075400 T8 DE 10075400T8 DE 10075400 T DE10075400 T DE 10075400T DE 10075400 T DE10075400 T DE 10075400T DE 10075400 T8 DE10075400 T8 DE 10075400T8
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coa
organism
aldehyde dehydrogenase
dependent aldehyde
pha
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DE10075400T
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DE10075400T1 (de
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Frank A. Skraly
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Yield10 Bioscience Inc
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Metabolix Inc
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    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • C12N9/0004—Oxidoreductases (1.)
    • C12N9/0008—Oxidoreductases (1.) acting on the aldehyde or oxo group of donors (1.2)
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52—Genes encoding for enzymes or proenzymes
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P7/00—Preparation of oxygen-containing organic compounds
    • C12P7/62—Carboxylic acid esters
    • C12P7/625—Polyesters of hydroxy carboxylic acids

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Microbiology (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Plant Pathology (AREA)
  • Physics & Mathematics (AREA)
  • Biophysics (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Materials For Medical Uses (AREA)
  • Medicinal Preparation (AREA)
  • Breeding Of Plants And Reproduction By Means Of Culturing (AREA)
  • Adhesives Or Adhesive Processes (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
  • Enzymes And Modification Thereof (AREA)
DE10075400T 2002-09-12 2003-09-12 Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden Active DE10075400T8 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41008702P 2002-09-12 2002-09-12
US410067P 2002-09-12
EP10075400.1A EP2365088B1 (de) 2002-09-12 2003-09-12 Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden

Publications (2)

Publication Number Publication Date
DE10075400T1 DE10075400T1 (de) 2012-10-11
DE10075400T8 true DE10075400T8 (de) 2013-04-25

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Family Applications (2)

Application Number Title Priority Date Filing Date
DE10075400T Active DE10075400T8 (de) 2002-09-12 2003-09-12 Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden
DE60336757T Expired - Lifetime DE60336757D1 (de) 2002-09-12 2003-09-12 Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege

Family Applications After (1)

Application Number Title Priority Date Filing Date
DE60336757T Expired - Lifetime DE60336757D1 (de) 2002-09-12 2003-09-12 Produktion von polyhydroxyalkanoat mittels coenzym-a-abhängiger aldehyd-dehydrogenase-wege

Country Status (8)

Country Link
US (1) US8071355B2 (de)
EP (2) EP1581619B1 (de)
JP (2) JP4628103B2 (de)
AT (1) ATE505559T1 (de)
AU (1) AU2003267185A1 (de)
DE (2) DE10075400T8 (de)
ES (1) ES2395053T3 (de)
WO (1) WO2004024876A2 (de)

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KR100979694B1 (ko) 2005-05-24 2010-09-02 한국과학기술원 폴리락테이트 또는 그 공중합체 생성능을 가지는 세포 또는식물 및 이를 이용한 폴리락테이트 또는 그 공중합체의제조방법
EP3214179B1 (de) 2007-03-16 2021-03-03 Genomatica, Inc. Zusammensetzungen und verfahren für die biosynthese von 1,4-butandiol und dessen vorläufern
US7947483B2 (en) 2007-08-10 2011-05-24 Genomatica, Inc. Methods and organisms for the growth-coupled production of 1,4-butanediol
JP5541809B2 (ja) * 2008-06-24 2014-07-09 エルジー・ケム・リミテッド ポリラクテートとその共重合体生成能が改善された変異微生物を利用したポリラクテートとその共重合体の製造方法
EP3514242A3 (de) 2008-09-10 2019-08-28 Genomatica, Inc. Mikroorganismen zur herstellung von 1,4-butandiol
US20100184173A1 (en) * 2008-11-14 2010-07-22 Genomatica, Inc. Microorganisms for the production of methyl ethyl ketone and 2-butanol
MY183971A (en) 2008-12-12 2021-03-17 Metabolix Inc Green process and compositions for producing poly(5hv) and 5 carbon chemicals
KR101293886B1 (ko) 2009-02-05 2013-08-07 주식회사 엘지화학 폴리락틱산 또는 폴리락틱산 공중합체 생성능을 지닌 재조합 랄스토니아 유트로파 및 이것을 이용하여 폴리락틱산 또는 폴리락틱산 공중합체를 제조하는 방법
WO2010141920A2 (en) 2009-06-04 2010-12-09 Genomatica, Inc. Microorganisms for the production of 1,4-butanediol and related methods
EP3199511B1 (de) * 2009-06-04 2020-01-29 Genomatica, Inc. Verfahren zur trennung von komponenten einer fermentierungsbrühe
CN105441374A (zh) * 2009-10-13 2016-03-30 基因组股份公司 生产1,4-丁二醇、4-羟基丁醛、4-羟基丁酰-coa、腐胺和相关化合物的微生物及其相关方法
US8530210B2 (en) 2009-11-25 2013-09-10 Genomatica, Inc. Microorganisms and methods for the coproduction 1,4-butanediol and gamma-butyrolactone
US8048661B2 (en) * 2010-02-23 2011-11-01 Genomatica, Inc. Microbial organisms comprising exogenous nucleic acids encoding reductive TCA pathway enzymes
US8445244B2 (en) 2010-02-23 2013-05-21 Genomatica, Inc. Methods for increasing product yields
FR2964014B1 (fr) * 2010-08-31 2013-04-05 Ifremer Nucleus enrobe d'un revetement filmogene aux proprietes antibacteriennes et cicatrisantes et procede d'obtention.
FR2968506B1 (fr) * 2010-12-14 2013-02-08 Ifremer Nucleus recouvert de pha
CN102212501B (zh) * 2011-03-31 2013-06-12 山东大学 一种重组大肠杆菌及应用其以单一碳源生产phbv的方法
WO2012149162A2 (en) * 2011-04-29 2012-11-01 Metabolix, Inc. Green process for producing polyhydroxyalkanoates and chemicals using a renewable feedstock
BR112014003708A2 (pt) 2011-08-19 2017-03-07 Genomatica Inc microorganismos métodos para a produção de 2,4-pentadienoato, butadieno, propileno, 1,3-butanodiol e álcoois relacionados
WO2013067432A1 (en) 2011-11-02 2013-05-10 Genomatica, Inc. Microorganisms and methods for the production of caprolactone
CN104685058B (zh) 2012-06-04 2020-07-07 基因组股份公司 制造4-羟基丁酸酯、1，4-丁二醇和相关化合物的微生物和方法
CN115960720A (zh) 2012-10-15 2023-04-14 基因组股份公司 用于生产特定长度脂肪醇及相关化合物的微生物和方法
WO2014152434A2 (en) 2013-03-15 2014-09-25 Genomatica, Inc. Microorganisms and methods for producing butadiene and related compounds by formate assimilation
EP3074504A4 (de) 2013-11-25 2017-05-03 Genomatica, Inc. Verfahren zur verbesserung der mikrobiellen herstellung von fettalkoholen mit bestimmter länge in gegenwart von methanol
US10487342B2 (en) 2014-07-11 2019-11-26 Genomatica, Inc. Microorganisms and methods for the production of butadiene using acetyl-CoA
EP4421181A2 (de) 2014-09-18 2024-08-28 Genomatica, Inc. Nichtnatürliche mikrobielle organismen mit verbesserter energieeffizienz
WO2016196233A1 (en) 2015-05-30 2016-12-08 Genomatica, Inc. Vinylisomerase-dehydratases, alkenol dehydratases, linalool dehydratases and/ crotyl alcohol dehydratases and methods for making and using them
US11059769B2 (en) 2017-10-26 2021-07-13 Noroo Ic Co., Ltd. Production and separation of 3-hydroxypropionic acid
US11566250B2 (en) 2017-10-26 2023-01-31 Noroo Ic Co., Ltd. Production and separation of 3-hydroxypropionic acid
JP7209434B2 (ja) * 2019-10-31 2023-01-20 株式会社カネカ ポリヒドロキシアルカン酸の製造方法およびその利用

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US4477654A (en) 1981-07-07 1984-10-16 Imperial Chemical Industries Plc 3-Hydroxybutyrate polymers
EP0145233B2 (de) 1983-11-23 1991-11-06 Imperial Chemical Industries Plc Trennungsverfahrenfür ein 3-hydroxybutyrat-Polymer
US5480794A (en) * 1987-06-29 1996-01-02 Massachusetts Institute Of Technology And Metabolix, Inc. Overproduction and purification of soluble PHA synthase
US5229279A (en) 1987-06-29 1993-07-20 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5245023A (en) * 1987-06-29 1993-09-14 Massachusetts Institute Of Technology Method for producing novel polyester biopolymers
US5250430A (en) * 1987-06-29 1993-10-05 Massachusetts Institute Of Technology Polyhydroxyalkanoate polymerase
GB9325952D0 (en) * 1993-12-20 1994-02-23 Zeneca Ltd Process for preparing films and coatings
PL181098B1 (pl) * 1994-01-28 2001-05-31 Procter & Gamble Wyrób absorbujący i kopolimer ulegający biodegradacji
ZA95627B (en) * 1994-01-28 1995-10-05 Procter & Gamble Biodegradable copolymers and plastic articles comprising biodegradable copolymers
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US5563239A (en) * 1994-11-09 1996-10-08 Eastman Chemical Company Composition and process for the production of poly(3-hydroxyalkanoates)
EP0958367B1 (de) * 1997-03-03 2005-06-08 Metabolix, Inc. Verfahren zur polyestern-biosynthese
AU725516B2 (en) * 1997-09-19 2000-10-12 Metabolix, Inc. Biological systems for manufacture of polyhydroxyalkanoate polymers containing 4-hydroxyacids
US7455999B2 (en) 1998-01-22 2008-11-25 Metabolix, Inc. Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate)
MXPA01001111A (es) * 1998-08-04 2002-04-24 Metabolix Inc Produccion de polihidroxialcanoato a partir de polioles.
EP1105499B1 (de) * 1998-08-18 2006-03-08 Metabolix, Inc. Transgene polyhydroxyalkanoat produzierende mikroben
EP2305324B1 (de) * 1999-03-25 2014-09-17 Metabolix, Inc. Medizinische Geräte und Anwendungen aus Polyhydroxyalkanoat-Polymeren
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AU2002225827A1 (en) * 2000-10-27 2002-05-06 Metabolix, Inc. Compositions comprising low molecular weight polyhydroxyalkanoates and methods employing same

Also Published As

Publication number Publication date
EP1581619B1 (de) 2011-04-13
DE10075400T1 (de) 2012-10-11
ATE505559T1 (de) 2011-04-15
EP2365088B1 (de) 2015-05-27
JP4628103B2 (ja) 2011-02-09
EP2365088A2 (de) 2011-09-14
EP1581619A2 (de) 2005-10-05
JP2006507811A (ja) 2006-03-09
ES2395053T3 (es) 2015-10-08
AU2003267185A1 (en) 2004-04-30
US20040106176A1 (en) 2004-06-03
ES2395053T1 (es) 2013-02-07
WO2004024876A3 (en) 2006-05-26
US8071355B2 (en) 2011-12-06
EP2365088A3 (de) 2012-01-11
AU2003267185A8 (en) 2004-04-30
DE60336757D1 (de) 2011-05-26
JP2010268797A (ja) 2010-12-02
WO2004024876A2 (en) 2004-03-25
EP1581619A4 (de) 2007-02-14

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