ATE319835T1 - Transgene polyhydroxyalkanoat produzierende mikroben - Google Patents
Transgene polyhydroxyalkanoat produzierende mikrobenInfo
- Publication number
- ATE319835T1 ATE319835T1 AT99943723T AT99943723T ATE319835T1 AT E319835 T1 ATE319835 T1 AT E319835T1 AT 99943723 T AT99943723 T AT 99943723T AT 99943723 T AT99943723 T AT 99943723T AT E319835 T1 ATE319835 T1 AT E319835T1
- Authority
- AT
- Austria
- Prior art keywords
- pha
- genes
- incorporated
- stabilizing
- integrated
- Prior art date
Links
- 230000009261 transgenic effect Effects 0.000 title abstract 2
- 239000005014 poly(hydroxyalkanoate) Substances 0.000 title 1
- 229920000903 polyhydroxyalkanoate Polymers 0.000 title 1
- 108090000623 proteins and genes Proteins 0.000 abstract 4
- 230000015572 biosynthetic process Effects 0.000 abstract 2
- 238000004519 manufacturing process Methods 0.000 abstract 2
- 239000013612 plasmid Substances 0.000 abstract 2
- 230000000087 stabilizing effect Effects 0.000 abstract 2
- 229910019142 PO4 Inorganic materials 0.000 abstract 1
- 239000003242 anti bacterial agent Substances 0.000 abstract 1
- 229940088710 antibiotic agent Drugs 0.000 abstract 1
- 230000003115 biocidal effect Effects 0.000 abstract 1
- 210000004027 cell Anatomy 0.000 abstract 1
- 210000000349 chromosome Anatomy 0.000 abstract 1
- 238000000855 fermentation Methods 0.000 abstract 1
- 230000004151 fermentation Effects 0.000 abstract 1
- 238000010348 incorporation Methods 0.000 abstract 1
- 108020004999 messenger RNA Proteins 0.000 abstract 1
- 230000000813 microbial effect Effects 0.000 abstract 1
- 238000002703 mutagenesis Methods 0.000 abstract 1
- 231100000350 mutagenesis Toxicity 0.000 abstract 1
- NBIIXXVUZAFLBC-UHFFFAOYSA-K phosphate Chemical compound [O-]P([O-])([O-])=O NBIIXXVUZAFLBC-UHFFFAOYSA-K 0.000 abstract 1
- 239000010452 phosphate Substances 0.000 abstract 1
- 238000010561 standard procedure Methods 0.000 abstract 1
Classifications
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
- C12N9/1029—Acyltransferases (2.3) transferring groups other than amino-acyl groups (2.3.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/87—Introduction of foreign genetic material using processes not otherwise provided for, e.g. co-transformation
- C12N15/90—Stable introduction of foreign DNA into chromosome
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/0004—Oxidoreductases (1.)
- C12N9/0006—Oxidoreductases (1.) acting on CH-OH groups as donors (1.1)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/1025—Acyltransferases (2.3)
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/10—Transferases (2.)
- C12N9/13—Transferases (2.) transferring sulfur containing groups (2.8)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
- C12N9/88—Lyases (4.)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P7/00—Preparation of oxygen-containing organic compounds
- C12P7/62—Carboxylic acid esters
- C12P7/625—Polyesters of hydroxy carboxylic acids
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/829—Alcaligenes
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- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/831—Azotobacter
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
- Y10S435/877—Pseudomonas putida
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Genetics & Genomics (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biotechnology (AREA)
- General Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Microbiology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Medicinal Chemistry (AREA)
- Plant Pathology (AREA)
- General Chemical & Material Sciences (AREA)
- Mycology (AREA)
- Physics & Mathematics (AREA)
- Biophysics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Virology (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Polyesters Or Polycarbonates (AREA)
- Biological Depolymerization Polymers (AREA)
- Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9685298P | 1998-08-18 | 1998-08-18 |
Publications (1)
Publication Number | Publication Date |
---|---|
ATE319835T1 true ATE319835T1 (de) | 2006-03-15 |
Family
ID=22259400
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
AT99943723T ATE319835T1 (de) | 1998-08-18 | 1999-08-17 | Transgene polyhydroxyalkanoat produzierende mikroben |
Country Status (10)
Country | Link |
---|---|
US (4) | US6593116B1 (de) |
EP (1) | EP1105499B1 (de) |
JP (2) | JP4623829B2 (de) |
KR (1) | KR100662896B1 (de) |
AT (1) | ATE319835T1 (de) |
AU (1) | AU753132B2 (de) |
CA (1) | CA2339421C (de) |
DE (1) | DE69930276T2 (de) |
MX (1) | MXPA01001750A (de) |
WO (1) | WO2000011188A1 (de) |
Families Citing this family (53)
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US6759219B2 (en) * | 1997-03-03 | 2004-07-06 | Metabolix, Inc. | Methods for the biosynthesis of polyesters |
US7455999B2 (en) * | 1998-01-22 | 2008-11-25 | Metabolix, Inc. | Transgenic systems for the manufacture of poly (3-hydroxy-butyrate-co-3-hydroxyhexanoate) |
ATE319835T1 (de) * | 1998-08-18 | 2006-03-15 | Metabolix Inc | Transgene polyhydroxyalkanoat produzierende mikroben |
AU2001275996B2 (en) * | 2000-07-21 | 2005-08-04 | Cj Cheiljedang Corporation | Production of polyhydroxyalkanoates from polyols |
CA2424178A1 (en) * | 2000-09-30 | 2002-04-11 | Diversa Corporation | Whole cell engineering by mutagenizing a substantial portion of a starting genome, combining mutations, and optionally repeating |
JP2003015168A (ja) * | 2001-04-27 | 2003-01-15 | Canon Inc | 電気泳動粒子、電気泳動粒子の製造方法、および電気泳動表示素子 |
DE10075400T8 (de) * | 2002-09-12 | 2013-04-25 | Metabolix, Inc. | Polyhydroxyalkanoatherstellung mittels Coenzym a-abhängigen Aldehyddehydrogenasepfaden |
US20070161097A1 (en) * | 2005-02-28 | 2007-07-12 | The Procter & Gamble Company | Deregulated bacteria with improved polyhydroxyalkanoate production |
CA2600882C (en) * | 2005-03-16 | 2013-02-26 | Metabolix, Inc. | Chemically inducible expression of biosynthetic pathways |
US20090130731A1 (en) * | 2005-03-24 | 2009-05-21 | Kaneka Corporation | Microorganism capable of accumulating ultra high molecular weight polyester |
CN101501182A (zh) | 2006-07-21 | 2009-08-05 | 株式会社钟化 | 基因取代微生物及使用该微生物的聚酯制造方法 |
US7384766B2 (en) * | 2006-07-26 | 2008-06-10 | Kaneka Corporation | Gene-substituted microorganisms, and production method of polyesters using the same |
JP5551448B2 (ja) | 2007-03-16 | 2014-07-16 | ジェノマティカ・インコーポレイテッド | 1,4−ブタンジオールおよびその前駆体の生合成のための組成物および方法 |
US7947483B2 (en) | 2007-08-10 | 2011-05-24 | Genomatica, Inc. | Methods and organisms for the growth-coupled production of 1,4-butanediol |
KR200453669Y1 (ko) * | 2007-12-07 | 2011-05-19 | 원정제관(주) | 용기 손잡이 |
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KR102176554B1 (ko) * | 2009-06-04 | 2020-11-09 | 게노마티카 인코포레이티드 | 발효액 성분들의 분리 방법 |
CN107384846B (zh) | 2009-06-04 | 2021-08-10 | 基因组股份公司 | 生产1,4-丁二醇的微生物和相关方法 |
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BR112014002859A2 (pt) | 2011-08-10 | 2017-06-13 | Metabolix Inc | purificação pós-processamento para produção de gama-butiro lactona |
BR112014009140B1 (pt) | 2011-10-25 | 2020-01-28 | Marrone Bio Innovations Inc | método para modular a infestação de uma praga |
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EP3101129B1 (de) * | 2014-01-31 | 2020-10-28 | Kaneka Corporation | Mikroorganismus mit angepasster expression von r-spezifischem enoyl-coa-hydratasegen und verfahren zur herstellung eines polyhydroxyalkanoat-copolymers damit |
EP2993228B1 (de) | 2014-09-02 | 2019-10-09 | Cargill, Incorporated | Herstellung von fettsäureestern |
CA2962920C (en) | 2014-10-01 | 2023-03-14 | Cryosa, Llc | Apparatus and methods for treatment of obstructive sleep apnea utilizing cryolysis of adipose tissues |
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US5811272A (en) * | 1996-07-26 | 1998-09-22 | Massachusetts Institute Of Technology | Method for controlling molecular weight of polyhydroxyalkanoates |
AU6169498A (en) * | 1997-02-13 | 1998-09-08 | James Madison University | Methods of making polyhydroxyalkanoates comprising 4-hydroxybutyrate monomer units |
DE69838768T2 (de) * | 1997-09-19 | 2008-10-30 | Metabolix, Inc., Cambridge | Biologische Systeme zur Herstellung von Polyhydroxyalkanoat-Polymeren die 4-Hy droxysäure enthalten |
EP1975236B1 (de) * | 1998-08-04 | 2015-05-06 | Metabolix, Inc. | Herstellung von Polyhydroxyalkanoat aus Polyolen |
ATE319835T1 (de) * | 1998-08-18 | 2006-03-15 | Metabolix Inc | Transgene polyhydroxyalkanoat produzierende mikroben |
-
1999
- 1999-08-17 AT AT99943723T patent/ATE319835T1/de not_active IP Right Cessation
- 1999-08-17 US US09/375,975 patent/US6593116B1/en not_active Expired - Lifetime
- 1999-08-17 KR KR1020017002093A patent/KR100662896B1/ko not_active IP Right Cessation
- 1999-08-17 DE DE69930276T patent/DE69930276T2/de not_active Expired - Lifetime
- 1999-08-17 WO PCT/US1999/018673 patent/WO2000011188A1/en active IP Right Grant
- 1999-08-17 JP JP2000566442A patent/JP4623829B2/ja not_active Expired - Fee Related
- 1999-08-17 AU AU56761/99A patent/AU753132B2/en not_active Ceased
- 1999-08-17 EP EP99943723A patent/EP1105499B1/de not_active Expired - Lifetime
- 1999-08-17 CA CA2339421A patent/CA2339421C/en not_active Expired - Fee Related
- 1999-08-17 MX MXPA01001750A patent/MXPA01001750A/es not_active IP Right Cessation
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2003
- 2003-06-13 US US10/461,069 patent/US6913911B2/en not_active Expired - Lifetime
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2005
- 2005-02-08 US US11/053,551 patent/US20050170480A1/en not_active Abandoned
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2007
- 2007-10-26 US US11/925,482 patent/US20100267016A1/en not_active Abandoned
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2010
- 2010-06-16 JP JP2010137239A patent/JP2010279358A/ja not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
DE69930276D1 (de) | 2006-05-04 |
AU753132B2 (en) | 2002-10-10 |
AU5676199A (en) | 2000-03-14 |
EP1105499A1 (de) | 2001-06-13 |
DE69930276T2 (de) | 2006-10-05 |
US20030228669A1 (en) | 2003-12-11 |
WO2000011188A9 (en) | 2002-04-11 |
US6593116B1 (en) | 2003-07-15 |
US20050170480A1 (en) | 2005-08-04 |
JP4623829B2 (ja) | 2011-02-02 |
EP1105499B1 (de) | 2006-03-08 |
MXPA01001750A (es) | 2002-04-08 |
CA2339421C (en) | 2011-10-11 |
KR100662896B1 (ko) | 2006-12-28 |
CA2339421A1 (en) | 2000-03-02 |
JP2002523050A (ja) | 2002-07-30 |
US6913911B2 (en) | 2005-07-05 |
KR20010082176A (ko) | 2001-08-29 |
WO2000011188A1 (en) | 2000-03-02 |
US20100267016A1 (en) | 2010-10-21 |
JP2010279358A (ja) | 2010-12-16 |
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