DE69816964D1 - Kombination von Glycosyl-Vitamin P und Trehalose zur Verbesserung der Blutzirkulation und Muskelsteifheit - Google Patents

Kombination von Glycosyl-Vitamin P und Trehalose zur Verbesserung der Blutzirkulation und Muskelsteifheit

Info

Publication number
DE69816964D1
DE69816964D1 DE69816964T DE69816964T DE69816964D1 DE 69816964 D1 DE69816964 D1 DE 69816964D1 DE 69816964 T DE69816964 T DE 69816964T DE 69816964 T DE69816964 T DE 69816964T DE 69816964 D1 DE69816964 D1 DE 69816964D1
Authority
DE
Germany
Prior art keywords
trehalose
combination
blood circulation
improve blood
muscle stiffness
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69816964T
Other languages
English (en)
Other versions
DE69816964T2 (de
Inventor
Shigeharu Fukuda
Toshio Miyake
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Hayashibara Seibutsu Kagaku Kenkyujo KK
Original Assignee
Hayashibara Seibutsu Kagaku Kenkyujo KK
Hayashibara Biochemical Laboratories Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hayashibara Seibutsu Kagaku Kenkyujo KK, Hayashibara Biochemical Laboratories Co Ltd filed Critical Hayashibara Seibutsu Kagaku Kenkyujo KK
Application granted granted Critical
Publication of DE69816964D1 publication Critical patent/DE69816964D1/de
Publication of DE69816964T2 publication Critical patent/DE69816964T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
    • A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P21/00—Drugs for disorders of the muscular or neuromuscular system
    • A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Epidemiology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
DE69816964T 1997-12-09 1998-11-23 Kombination von Glycosyl-Vitamin P und Trehalose zur Verbesserung der Blutzirkulation und Muskelsteifheit Expired - Lifetime DE69816964T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP35405997 1997-12-09
JP35405997A JP4295840B2 (ja) 1997-12-09 1997-12-09 血行改善剤

Publications (2)

Publication Number Publication Date
DE69816964D1 true DE69816964D1 (de) 2003-09-11
DE69816964T2 DE69816964T2 (de) 2004-06-17

Family

ID=18435025

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69816964T Expired - Lifetime DE69816964T2 (de) 1997-12-09 1998-11-23 Kombination von Glycosyl-Vitamin P und Trehalose zur Verbesserung der Blutzirkulation und Muskelsteifheit

Country Status (6)

Country Link
US (1) US5981498A (de)
EP (1) EP0938899B1 (de)
JP (1) JP4295840B2 (de)
KR (1) KR100588952B1 (de)
DE (1) DE69816964T2 (de)
TW (1) TW533077B (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP4203159B2 (ja) * 1997-12-09 2008-12-24 株式会社林原生物化学研究所 神経機能調節剤
WO2001014396A1 (en) * 1999-08-19 2001-03-01 Korea Research Institute Of Bioscience And Biotechnology Flavonoids derived from citrus peels as collagen-induced platelet aggregation inhibitor
US6159943A (en) * 1999-09-24 2000-12-12 Bioenergy, Inc. Use of ribose to prevent cramping and soreness in muscles
US8642051B2 (en) 2000-03-21 2014-02-04 Suzanne Jaffe Stillman Method of hydration; infusion packet system(s), support member(s), delivery system(s), and method(s); with business model(s) and Method(s)
EP1268305B1 (de) 2000-03-21 2007-09-12 Suzanne Jaffe Stillman Aufgussbeutel mit dekorativen gebrauchsmitteln, trägerelementen, abgabevorrichtung und verfahren
JP4754066B2 (ja) * 2000-12-22 2011-08-24 株式会社林原生物化学研究所 抗関節障害剤
JP4397142B2 (ja) * 2001-11-20 2010-01-13 株式会社林原生物化学研究所 活性酸素消去能低減抑制剤
US20050065030A1 (en) * 2001-11-20 2005-03-24 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Reduction inhibitory agent for active oxygen eliminating activity
FR2841472B1 (fr) * 2002-06-28 2006-02-24 Agronomique Inst Nat Rech Composition nutritionnelle ou therapeutique contenant le compose hesperidine ou l'un de ses derives
KR101054913B1 (ko) * 2003-12-31 2011-08-05 주식회사 삼양제넥스 식물스테롤, 헤스페리딘 및 루틴을 포함하는 고지혈증,동맥경화증 및 간질환 예방 및 치료용 조성물
JP5000884B2 (ja) * 2004-12-02 2012-08-15 江崎グリコ株式会社 へスペレチン包接化合物およびナリンゲニン包接化合物の合成方法
AT501682A1 (de) * 2005-01-14 2006-10-15 Hermine Dr Engl Verfahren zur herstellung einer wirkstoffmischung
AT501221A1 (de) * 2005-01-14 2006-07-15 Hermine Dr Engl Wirkstoffmischung
JP5781727B2 (ja) * 2007-02-23 2015-09-24 株式会社ネクスト２１ 血管攣縮の治療剤又は予防剤
JP2009007256A (ja) * 2007-06-26 2009-01-15 Kao Corp Ｎａｄｈ／ｎａｄｐｈオキシダーゼ抑制剤
JP2009007313A (ja) * 2007-06-29 2009-01-15 Lion Corp 筋萎縮抑制剤
JPWO2010029913A1 (ja) * 2008-09-11 2012-02-02 株式会社林原生物化学研究所 気力改善剤
JP6195848B2 (ja) 2012-01-27 2017-09-13 ザ、リージェンツ、オブ、ザ、ユニバーシティ、オブ、カリフォルニアＴｈｅ Ｒｅｇｅｎｔｓ Ｏｆ Ｔｈｅ Ｕｎｉｖｅｒｓｉｔｙ Ｏｆ Ｃａｌｉｆｏｒｎｉａ 糖ポリマーを用いた生体分子の安定化
US9392814B2 (en) 2014-06-06 2016-07-19 Nicholas J. Singer Delivery system for drinks
USD773313S1 (en) 2015-06-23 2016-12-06 Nicholas J. Singer Package
JP7140533B2 (ja) * 2017-08-30 2022-09-21 東洋精糖株式会社 眼精疲労改善用または目のピント調節力低下改善用組成物
JP6826347B2 (ja) * 2018-05-23 2021-02-03 長崎県公立大学法人 冷え性改善用、肩こり改善用、疲労回復用又は睡眠改善用の組成物、それを含む食品、薬剤、組成物キット、及び、その組成物の製造方法

Family Cites Families (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR8012M (de) * 1967-10-20 1970-07-27
SU681841A1 (ru) * 1978-03-06 1981-03-07 Московский Ордена Ленина И Ордена Трудового Коасного Знаменимедецинский Институт Им.И.M.Сеченова Способ получени рутина
JP2926411B2 (ja) * 1989-03-08 1999-07-28 株式会社林原生物化学研究所 α―グリコシル ルチンの製造方法とその用途
JP3177892B2 (ja) * 1989-04-15 2001-06-18 株式会社林原生物化学研究所 α―グリコシルルチンの製造法とその用途
US5145781A (en) * 1989-03-08 1992-09-08 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Preparation and uses of alpha-glycosyl rutin
JP3060227B2 (ja) * 1989-06-03 2000-07-10 株式会社林原生物化学研究所 α―グリコシル ヘスペリジンとその製造方法並びに用途
JP3194145B2 (ja) * 1989-09-28 2001-07-30 株式会社林原生物化学研究所 ４Ｇ―α―Ｄ―グルコピラノシルルチンとその製造方法並びに用途
JP2926432B2 (ja) * 1990-06-11 1999-07-28 株式会社林原生物化学研究所 養毛剤
JP2896598B2 (ja) * 1990-10-06 1999-05-31 株式会社林原生物化学研究所 ラクトネオトレハロースとその製造方法並びに用途
JP3082094B2 (ja) * 1990-11-15 2000-08-28 株式会社林原生物化学研究所 ネオトレハロースの製造方法とその用途
US5494667A (en) * 1992-06-04 1996-02-27 Kabushiki Kaisha Hayahibara Topically applied hair restorer containing pine extract
EP0691344B1 (de) * 1992-12-28 2003-03-19 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Reinigung von Trehalose
JP3559585B2 (ja) * 1993-06-03 2004-09-02 株式会社林原生物化学研究所 トレハロース遊離酵素とその製造方法並びに用途
JPH0725761A (ja) * 1993-07-09 1995-01-27 Kureha Chem Ind Co Ltd 軟骨保護剤
DE69510116T2 (de) * 1994-02-23 1999-11-18 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo, Okayama Nicht reduzierendes Saccharid bildendes Enzym, dieses kodierende DNA, und deren Herstellungen und Verwendungen
JP3557272B2 (ja) * 1994-02-23 2004-08-25 株式会社林原生物化学研究所 組換え型酵素とその製造方法並びに用途
JP3559609B2 (ja) * 1994-03-07 2004-09-02 株式会社林原生物化学研究所 組換え型酵素とその製造方法並びに用途
DE69532485T2 (de) * 1994-03-07 2004-11-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose-freisetzendes Enzym, dafür kodierende DNA, Herstellung und Verwendung
JP3557277B2 (ja) * 1994-06-25 2004-08-25 株式会社林原生物化学研究所 耐熱性トレハロース遊離酵素とその製造方法並びに用途
JP3793590B2 (ja) * 1994-06-27 2006-07-05 株式会社林原生物化学研究所 非還元性糖質とその製造方法並びに用途
JP3557287B2 (ja) * 1994-06-24 2004-08-25 株式会社林原生物化学研究所 耐熱性非還元性糖質生成酵素とその製造方法並びに用途
AU695080B2 (en) * 1994-06-24 1998-08-06 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Thermostable non-reducing saccharide-forming enzyme, its production and uses
JP3616166B2 (ja) * 1994-07-19 2005-02-02 株式会社林原生物化学研究所 トレハロースとその製造方法並びに用途
EP0693558B1 (de) * 1994-07-19 2002-12-04 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Trehalose, ihre Herstellung und ihre Verwendung
JP3557289B2 (ja) * 1994-07-21 2004-08-25 株式会社林原生物化学研究所 非還元性糖質からトレハロースを遊離する組換え型耐熱性酵素
JP3557288B2 (ja) * 1994-07-21 2004-08-25 株式会社林原生物化学研究所 還元性澱粉糖から末端にトレハロース構造を有する非還元性糖質を生成する組換え型耐熱性酵素
JP3810457B2 (ja) * 1994-10-01 2006-08-16 株式会社林原生物化学研究所 マルトースをトレハロースに変換する組換え型耐熱性酵素
KR0182395B1 (ko) * 1995-12-08 1999-04-01 권계홍 트레할로스를 안정제로 이용한 단백질용액의 액상가열처리방법
EP0868916A3 (de) * 1997-03-04 2004-09-15 Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo Reduktionshemmungsmittel für Aktiv-Sauerstoff entfernende Aktivität
JP4203159B2 (ja) * 1997-12-09 2008-12-24 株式会社林原生物化学研究所 神経機能調節剤

Also Published As

Publication number Publication date
EP0938899A2 (de) 1999-09-01
EP0938899B1 (de) 2003-08-06
JP4295840B2 (ja) 2009-07-15
US5981498A (en) 1999-11-09
DE69816964T2 (de) 2004-06-17
KR19990062596A (ko) 1999-07-26
JPH11171778A (ja) 1999-06-29
KR100588952B1 (ko) 2006-10-13
EP0938899A3 (de) 2000-09-20
TW533077B (en) 2003-05-21

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