DE69816964D1 - Combination of glycosyl vitamin P and trehalose to improve blood circulation and muscle stiffness - Google Patents
Combination of glycosyl vitamin P and trehalose to improve blood circulation and muscle stiffnessInfo
- Publication number
- DE69816964D1 DE69816964D1 DE69816964T DE69816964T DE69816964D1 DE 69816964 D1 DE69816964 D1 DE 69816964D1 DE 69816964 T DE69816964 T DE 69816964T DE 69816964 T DE69816964 T DE 69816964T DE 69816964 D1 DE69816964 D1 DE 69816964D1
- Authority
- DE
- Germany
- Prior art keywords
- trehalose
- combination
- blood circulation
- improve blood
- muscle stiffness
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7042—Compounds having saccharide radicals and heterocyclic rings
- A61K31/7048—Compounds having saccharide radicals and heterocyclic rings having oxygen as a ring hetero atom, e.g. leucoglucosan, hesperidin, erythromycin, nystatin, digitoxin or digoxin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P21/00—Drugs for disorders of the muscular or neuromuscular system
- A61P21/02—Muscle relaxants, e.g. for tetanus or cramps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Molecular Biology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurology (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Biochemistry (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP35405997 | 1997-12-09 | ||
JP35405997A JP4295840B2 (en) | 1997-12-09 | 1997-12-09 | Blood circulation improving agent |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69816964D1 true DE69816964D1 (en) | 2003-09-11 |
DE69816964T2 DE69816964T2 (en) | 2004-06-17 |
Family
ID=18435025
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69816964T Expired - Lifetime DE69816964T2 (en) | 1997-12-09 | 1998-11-23 | Combination of glycosyl vitamin P and trehalose to improve blood circulation and muscle stiffness |
Country Status (6)
Country | Link |
---|---|
US (1) | US5981498A (en) |
EP (1) | EP0938899B1 (en) |
JP (1) | JP4295840B2 (en) |
KR (1) | KR100588952B1 (en) |
DE (1) | DE69816964T2 (en) |
TW (1) | TW533077B (en) |
Families Citing this family (22)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP4203159B2 (en) * | 1997-12-09 | 2008-12-24 | 株式会社林原生物化学研究所 | Nerve function regulator |
WO2001014396A1 (en) * | 1999-08-19 | 2001-03-01 | Korea Research Institute Of Bioscience And Biotechnology | Flavonoids derived from citrus peels as collagen-induced platelet aggregation inhibitor |
US6159943A (en) * | 1999-09-24 | 2000-12-12 | Bioenergy, Inc. | Use of ribose to prevent cramping and soreness in muscles |
EP1268305B1 (en) | 2000-03-21 | 2007-09-12 | Suzanne Jaffe Stillman | Infusion packet with useful and decorative elements, support member, delivery system and method |
US8642051B2 (en) | 2000-03-21 | 2014-02-04 | Suzanne Jaffe Stillman | Method of hydration; infusion packet system(s), support member(s), delivery system(s), and method(s); with business model(s) and Method(s) |
JP4754066B2 (en) * | 2000-12-22 | 2011-08-24 | 株式会社林原生物化学研究所 | Anti-joint disorder |
JP4397142B2 (en) * | 2001-11-20 | 2010-01-13 | 株式会社林原生物化学研究所 | Reactive oxygen scavenging reduction inhibitor |
US20050065030A1 (en) * | 2001-11-20 | 2005-03-24 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Reduction inhibitory agent for active oxygen eliminating activity |
FR2841472B1 (en) * | 2002-06-28 | 2006-02-24 | Agronomique Inst Nat Rech | NUTRITIONAL OR THERAPEUTIC COMPOSITION CONTAINING THE HESPERIDINE COMPOUND OR ONE OF ITS DERIVATIVES |
KR101054913B1 (en) * | 2003-12-31 | 2011-08-05 | 주식회사 삼양제넥스 | Composition for preventing and treating hyperlipidemia, arteriosclerosis and liver disease, including phytosterol, hesperidin and rutin |
JP5000884B2 (en) * | 2004-12-02 | 2012-08-15 | 江崎グリコ株式会社 | Method for synthesizing hesperetin inclusion compound and naringenin inclusion compound |
AT501221A1 (en) * | 2005-01-14 | 2006-07-15 | Hermine Dr Engl | ACTIVE COMPOUND |
AT501682A1 (en) * | 2005-01-14 | 2006-10-15 | Hermine Dr Engl | METHOD FOR PRODUCING AN ACTIVE SUBSTANCE MIXTURE |
WO2008102563A1 (en) | 2007-02-23 | 2008-08-28 | Next21 K.K. | Therapeutic or prophylactic agent for vasoconstriction |
JP2009007256A (en) * | 2007-06-26 | 2009-01-15 | Kao Corp | Nadh/nadph oxidase inhibitor |
JP2009007313A (en) * | 2007-06-29 | 2009-01-15 | Lion Corp | Amyotrophy inhibitor |
JPWO2010029913A1 (en) * | 2008-09-11 | 2012-02-02 | 株式会社林原生物化学研究所 | Kiln improver |
US9901648B2 (en) | 2012-01-27 | 2018-02-27 | The Regents Of The University Of California | Stabilization of biomolecules using sugar polymers |
US9392814B2 (en) | 2014-06-06 | 2016-07-19 | Nicholas J. Singer | Delivery system for drinks |
USD773313S1 (en) | 2015-06-23 | 2016-12-06 | Nicholas J. Singer | Package |
JP7140533B2 (en) * | 2017-08-30 | 2022-09-21 | 東洋精糖株式会社 | Composition for ameliorating asthenopia or for ameliorating decreased focusing ability of eyes |
JP6826347B2 (en) * | 2018-05-23 | 2021-02-03 | 長崎県公立大学法人 | Compositions for improving poor circulation, improving stiff shoulders, recovering from fatigue or improving sleep, foods, drugs, composition kits containing them, and methods for producing the compositions. |
Family Cites Families (30)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
FR8012M (en) * | 1967-10-20 | 1970-07-27 | ||
SU681841A1 (en) * | 1978-03-06 | 1981-03-07 | Московский Ордена Ленина И Ордена Трудового Коасного Знаменимедецинский Институт Им.И.M.Сеченова | Method of rutin production |
ATE118550T1 (en) * | 1989-03-08 | 1995-03-15 | Hayashibara Biochem Lab | PREPARATION AND USES OF ALPHA-GLYCOSYL RUTIN. |
JP3177892B2 (en) * | 1989-04-15 | 2001-06-18 | 株式会社林原生物化学研究所 | Production method of α-glycosylrutin and its use |
JP2926411B2 (en) * | 1989-03-08 | 1999-07-28 | 株式会社林原生物化学研究所 | Production method of α-glycosyl rutin and its use |
JP3060227B2 (en) * | 1989-06-03 | 2000-07-10 | 株式会社林原生物化学研究所 | α-Glycosyl hesperidin, its production method and use |
JP3194145B2 (en) * | 1989-09-28 | 2001-07-30 | 株式会社林原生物化学研究所 | 4G-α-D-glucopyranosylrutin, production method and use thereof |
JP2926432B2 (en) * | 1990-06-11 | 1999-07-28 | 株式会社林原生物化学研究所 | Hair restorer |
JP2896598B2 (en) * | 1990-10-06 | 1999-05-31 | 株式会社林原生物化学研究所 | Lactoneotrehalose, its production method and use |
JP3082094B2 (en) * | 1990-11-15 | 2000-08-28 | 株式会社林原生物化学研究所 | Method for producing neotrehalose and its use |
US5494667A (en) * | 1992-06-04 | 1996-02-27 | Kabushiki Kaisha Hayahibara | Topically applied hair restorer containing pine extract |
ES2136115T3 (en) * | 1992-12-28 | 1999-11-16 | Hayashibara Biochem Lab | ENZYME FORMING NON-REDUCING SUCCARIDS, AND THEIR PREPARATION AND USES. |
JP3559585B2 (en) * | 1993-06-03 | 2004-09-02 | 株式会社林原生物化学研究所 | Trehalose-releasing enzyme, its production method and use |
JPH0725761A (en) * | 1993-07-09 | 1995-01-27 | Kureha Chem Ind Co Ltd | Agent for protecting cartilage |
JP3557272B2 (en) * | 1994-02-23 | 2004-08-25 | 株式会社林原生物化学研究所 | Recombinant enzyme, its production method and use |
DE69510116T2 (en) * | 1994-02-23 | 1999-11-18 | Hayashibara Biochem Lab | Non-reducing saccharide-forming enzyme, this coding DNA, and their preparations and uses |
EP0671470B9 (en) * | 1994-03-07 | 2004-11-03 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Trehalose releasing enzyme, DNA encoding therefor, their preparation and uses |
JP3559609B2 (en) * | 1994-03-07 | 2004-09-02 | 株式会社林原生物化学研究所 | Recombinant enzyme, its production method and use |
JP3557277B2 (en) * | 1994-06-25 | 2004-08-25 | 株式会社林原生物化学研究所 | Thermostable trehalose releasing enzyme, its production method and use |
JP3793590B2 (en) * | 1994-06-27 | 2006-07-05 | 株式会社林原生物化学研究所 | Non-reducing saccharides, production method and use thereof |
JP3557287B2 (en) * | 1994-06-24 | 2004-08-25 | 株式会社林原生物化学研究所 | Thermostable non-reducing saccharide-forming enzyme, its production method and use |
US5714368A (en) * | 1994-06-24 | 1998-02-03 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Thermostable non-reducing saccharide-forming enzyme its production and uses |
EP0693558B1 (en) * | 1994-07-19 | 2002-12-04 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Trehalose and its production and use |
JP3616166B2 (en) * | 1994-07-19 | 2005-02-02 | 株式会社林原生物化学研究所 | Trehalose and its production method and use |
JP3557288B2 (en) * | 1994-07-21 | 2004-08-25 | 株式会社林原生物化学研究所 | Recombinant thermostable enzyme that produces non-reducing carbohydrates with terminal trehalose structure from reducing starch sugars |
JP3557289B2 (en) * | 1994-07-21 | 2004-08-25 | 株式会社林原生物化学研究所 | Recombinant thermostable enzyme that releases trehalose from non-reducing carbohydrates |
JP3810457B2 (en) * | 1994-10-01 | 2006-08-16 | 株式会社林原生物化学研究所 | Recombinant thermostable enzyme that converts maltose to trehalose |
KR0182395B1 (en) * | 1995-12-08 | 1999-04-01 | 권계홍 | Heat treatment of protein liquid using trehalose as a stabilizer |
EP0868916A3 (en) * | 1997-03-04 | 2004-09-15 | Kabushiki Kaisha Hayashibara Seibutsu Kagaku Kenkyujo | Reduction inhibitory agent for active-oxygen eliminating activity |
JP4203159B2 (en) * | 1997-12-09 | 2008-12-24 | 株式会社林原生物化学研究所 | Nerve function regulator |
-
1997
- 1997-12-09 JP JP35405997A patent/JP4295840B2/en not_active Expired - Lifetime
-
1998
- 1998-11-10 US US09/188,405 patent/US5981498A/en not_active Expired - Lifetime
- 1998-11-16 TW TW087118928A patent/TW533077B/en not_active IP Right Cessation
- 1998-11-23 EP EP98309544A patent/EP0938899B1/en not_active Expired - Lifetime
- 1998-11-23 DE DE69816964T patent/DE69816964T2/en not_active Expired - Lifetime
- 1998-11-24 KR KR1019980050406A patent/KR100588952B1/en active IP Right Grant
Also Published As
Publication number | Publication date |
---|---|
EP0938899A2 (en) | 1999-09-01 |
JP4295840B2 (en) | 2009-07-15 |
US5981498A (en) | 1999-11-09 |
EP0938899A3 (en) | 2000-09-20 |
KR100588952B1 (en) | 2006-10-13 |
DE69816964T2 (en) | 2004-06-17 |
KR19990062596A (en) | 1999-07-26 |
JPH11171778A (en) | 1999-06-29 |
TW533077B (en) | 2003-05-21 |
EP0938899B1 (en) | 2003-08-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |