DE69739473D1 - Spezies-spezifische, genus-spezifische und universelle DNA Sonden und Amplifikationsprimer zur schnellen Erkennung und Identifizierung von pathogenen Bakterien und Pilzen und assoziierten Antibiotikaresistenzgenen aus klinischen Proben für die Diagnose in mikrobiologischen Laboratorien. - Google Patents

Spezies-spezifische, genus-spezifische und universelle DNA Sonden und Amplifikationsprimer zur schnellen Erkennung und Identifizierung von pathogenen Bakterien und Pilzen und assoziierten Antibiotikaresistenzgenen aus klinischen Proben für die Diagnose in mikrobiologischen Laboratorien.

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Publication number
DE69739473D1
DE69739473D1 DE69739473T DE69739473T DE69739473D1 DE 69739473 D1 DE69739473 D1 DE 69739473D1 DE 69739473 T DE69739473 T DE 69739473T DE 69739473 T DE69739473 T DE 69739473T DE 69739473 D1 DE69739473 D1 DE 69739473D1
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Prior art keywords
species
specific
resistance genes
identification
diagnosis
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DE69739473T
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Michel G Bergeron
Francois J Picard
Marc Ouellette
Paul H Roy
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GeneOhm Sciences Canada Inc
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GeneOhm Sciences Canada Inc
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/689Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for bacteria
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
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    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/21Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pseudomonadaceae (F)
    • C07K14/212Moraxellaceae, e.g. Acinetobacter, Moraxella, Oligella, Psychrobacter
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/245Escherichia (G)
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    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/24Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Enterobacteriaceae (F), e.g. Citrobacter, Serratia, Proteus, Providencia, Morganella, Yersinia
    • C07K14/26Klebsiella (G)
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    • C07ORGANIC CHEMISTRY
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/285Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Pasteurellaceae (F), e.g. Haemophilus influenza
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    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/315Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci
    • C07K14/3156Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Streptococcus (G), e.g. Enterococci from Streptococcus pneumoniae (Pneumococcus)
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    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6888Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms
    • C12Q1/6895Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for detection or identification of organisms for plants, fungi or algae
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00Oligonucleotides characterized by their use
    • C12Q2600/156Polymorphic or mutational markers

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  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Health & Medical Sciences (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Analytical Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • Communicable Diseases (AREA)
  • Botany (AREA)
  • Mycology (AREA)
  • Pulmonology (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69739473T 1996-11-04 1997-11-04 Spezies-spezifische, genus-spezifische und universelle DNA Sonden und Amplifikationsprimer zur schnellen Erkennung und Identifizierung von pathogenen Bakterien und Pilzen und assoziierten Antibiotikaresistenzgenen aus klinischen Proben für die Diagnose in mikrobiologischen Laboratorien. Expired - Lifetime DE69739473D1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US08/743,637 US5994066A (en) 1995-09-11 1996-11-04 Species-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
PCT/CA1997/000829 WO1998020157A2 (en) 1996-11-04 1997-11-04 Species-specific, genus-specific and universal dna probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories

Publications (1)

Publication Number Publication Date
DE69739473D1 true DE69739473D1 (de) 2009-08-06

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DE69739473T Expired - Lifetime DE69739473D1 (de) 1996-11-04 1997-11-04 Spezies-spezifische, genus-spezifische und universelle DNA Sonden und Amplifikationsprimer zur schnellen Erkennung und Identifizierung von pathogenen Bakterien und Pilzen und assoziierten Antibiotikaresistenzgenen aus klinischen Proben für die Diagnose in mikrobiologischen Laboratorien.

Country Status (14)

Country Link
US (1) US5994066A (de)
EP (8) EP0943009B1 (de)
JP (3) JP2001504330A (de)
CN (1) CN1248295A (de)
AT (2) ATE552352T1 (de)
AU (1) AU731850B2 (de)
BR (1) BR9713494A (de)
CA (4) CA2790915C (de)
DE (1) DE69739473D1 (de)
DK (1) DK0943009T3 (de)
ES (1) ES2329202T3 (de)
NO (1) NO991976L (de)
NZ (1) NZ335548A (de)
WO (1) WO1998020157A2 (de)

Families Citing this family (184)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US20020055101A1 (en) * 1995-09-11 2002-05-09 Michel G. Bergeron Specific and universal probes and amplification primers to rapidly detect and identify common bacterial pathogens and antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US6905670B2 (en) 1995-03-28 2005-06-14 The General Hospital Corporation Methods of screening compounds useful for prevention of infection or pathogenicity
ES2288760T3 (es) 1996-04-25 2008-01-16 Bioarray Solutions Ltd. Ensamblaje electrocinetico controlado por luz de particulas proximas a superficies.
US20030049636A1 (en) * 1999-05-03 2003-03-13 Bergeron Michel G. Species-specific, genus-specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial and fungal pathogens and associated antibiotic resistance genes from clinical specimens for diagnosis in microbiology laboratories
US20100267012A1 (en) * 1997-11-04 2010-10-21 Bergeron Michel G Highly conserved genes and their use to generate probes and primers for detection of microorganisms
US6558901B1 (en) * 1997-05-02 2003-05-06 Biomerieux Vitek Nucleic acid assays
US6570001B1 (en) * 1997-06-20 2003-05-27 Institut Pasteur Polynucleotides and their use for detecting resistance to streptogramin A or to streptogramin B and related compounds
US6800744B1 (en) * 1997-07-02 2004-10-05 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Streptococcus pneumoniae for diagnostics and therapeutics
DE19731292A1 (de) * 1997-07-21 1999-01-28 Biotecon Ges Fuer Biotechnologische Entwicklung & Consulting Mbh Nucleinsäuremolekül, Kit und Verwendung
US7060458B1 (en) * 1997-08-14 2006-06-13 Wyeth Nucleic acid and amino acid sequences relating to Staphylococcus epidermidis for diagnostics and therapeutics
US6355411B1 (en) 1997-11-25 2002-03-12 The General Hospital Corporation Virulence-associated nucleic acid sequences and uses thereof
CA2318726C (en) 1998-01-23 2009-07-28 Pieter Oudshoorn Ef-tu mrna as a marker for viability of bacteria
US6468743B1 (en) * 1998-05-18 2002-10-22 Conagra Grocery Products Company PCR techniques for detecting microbial contaminants in foodstuffs
BR9910646A (pt) 1998-05-22 2001-01-30 Creatogen Ag Detecção de resistências aos antibióticos em microorganismos
AU5612099A (en) * 1998-09-03 2000-03-27 University Of British Columbia, The Method for the identification and speciation of bacteria of the (burkholderia cepacia) complex
US6242223B1 (en) * 1998-09-28 2001-06-05 Creighton University Primers for use in detecting beta-lactamases
US6451556B1 (en) 1998-12-21 2002-09-17 Smithkline Beecham Corporation EF-Tu
GB9904804D0 (en) * 1999-03-02 1999-04-28 King S College London Identification of bacteria
ES2535961T3 (es) * 1999-04-09 2015-05-19 Zoetis P&U Llc Bacteria pasteurelácea atenuada que tiene una mutación en un gen de virulencia
US6605709B1 (en) 1999-04-09 2003-08-12 Genome Therapeutics Corporation Nucleic acid and amino acid sequences relating to Proteus mirabilis for diagnostics and therapeutics
US6066461A (en) * 1999-04-12 2000-05-23 Becton Dickinson And Company Amplification and detection of Campylobacter jejuni and Campylobacter coli
US6821770B1 (en) * 1999-05-03 2004-11-23 Gen-Probe Incorporated Polynucleotide matrix-based method of identifying microorganisms
CA2811455C (en) * 1999-09-28 2015-12-08 Geneohm Sciences Canada Inc. Nucleic acids and methods for the detection of coagulase-negative staphylococcus
US20030134293A1 (en) * 1999-11-16 2003-07-17 Zhiping Liu Method for rapid and accurate identification of microorganisms
EP1261716A2 (de) * 1999-11-16 2002-12-04 Apollo Biotechnology, Inc. Methode zur schnellen und genauen identifizierung von mikroorganismen
EP1118677A1 (de) * 2000-01-17 2001-07-25 Novartis AG Oligonukleotide zum nachweis fungizid-resistenter pflanzenpathogener pilze
US8076063B2 (en) 2000-02-07 2011-12-13 Illumina, Inc. Multiplexed methylation detection methods
US7955794B2 (en) 2000-09-21 2011-06-07 Illumina, Inc. Multiplex nucleic acid reactions
US7582420B2 (en) 2001-07-12 2009-09-01 Illumina, Inc. Multiplex nucleic acid reactions
US7112716B2 (en) 2000-04-06 2006-09-26 The General Hospital Corporation Methods for screening and identifying host pathogen defense genes
US20020102678A1 (en) * 2000-04-14 2002-08-01 Solh Nevine El Staphylococcal gene, vgaC, conferring resistance to streptogramin A and related compounds
DE60133321T2 (de) * 2000-05-29 2009-03-05 Tosoh Corp. Methoden zur Detektion des mecA Gens beim methicillin-resistenten Staphylococcus Aureus
CA2635452A1 (en) 2000-06-21 2001-12-27 Bioarray Solutions, Ltd. Looped probe design to control hybridization stringency
US9709559B2 (en) 2000-06-21 2017-07-18 Bioarray Solutions, Ltd. Multianalyte molecular analysis using application-specific random particle arrays
US6261785B1 (en) 2000-07-27 2001-07-17 Becton, Dickinson And Company Amplification and detection of Bordetella pertussis
US20040005555A1 (en) * 2000-08-31 2004-01-08 Rothman Richard E. Molecular diagnosis of bactermia
GB0022017D0 (en) * 2000-09-08 2000-10-25 Univ Dundee Cell assays
US20020086313A1 (en) * 2000-09-25 2002-07-04 Kilbane John J. Application of bioinformatics for direct study of unculturable microorganisms
AU2013231102B2 (en) * 2001-03-02 2016-04-28 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US7226739B2 (en) 2001-03-02 2007-06-05 Isis Pharmaceuticals, Inc Methods for rapid detection and identification of bioagents in epidemiological and forensic investigations
US20040121335A1 (en) 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents associated with host versus graft and graft versus host rejections
US7718354B2 (en) 2001-03-02 2010-05-18 Ibis Biosciences, Inc. Methods for rapid identification of pathogens in humans and animals
US20040121314A1 (en) * 2002-12-06 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in containers
AT410444B (de) * 2001-03-02 2003-04-25 Oesterr Forsch Seibersdorf Verfahren zur detektion von nukleinsäuremolekülen
US7666588B2 (en) 2001-03-02 2010-02-23 Ibis Biosciences, Inc. Methods for rapid forensic analysis of mitochondrial DNA and characterization of mitochondrial DNA heteroplasmy
US20040121310A1 (en) * 2002-12-18 2004-06-24 Ecker David J. Methods for rapid detection and identification of bioagents in forensic studies
US20030027135A1 (en) * 2001-03-02 2003-02-06 Ecker David J. Method for rapid detection and identification of bioagents
US7052837B2 (en) * 2001-03-13 2006-05-30 The Board Of Trustees Of The University Of Arkansas Histoplasma capsulatum catalase sequences and their use in the detection of Histoplamsa capsulatum and histoplasmosis
DE10124342A1 (de) * 2001-05-18 2002-11-28 Biotecon Diagnostics Gmbh Verfahren zum Nachweis von Mikroorganismen der Spezies Yersinia pestis/Yersinia pseudotuberculosis und/oder zur Differzierung zwischen Yersinia pestis und Yersinia pseudotuberculosis
CA2348042A1 (en) 2001-06-04 2002-12-04 Ann Huletsky Sequences for detection and identification of methicillin-resistant staphylococcus aureus
US7262063B2 (en) 2001-06-21 2007-08-28 Bio Array Solutions, Ltd. Directed assembly of functional heterostructures
EP1409738A4 (de) * 2001-06-22 2005-03-30 Marshfield Clinic Verfahren und oligonukleotide zum nachweis von salmonella sp.-,e.coli o157:h7- und listeria-monozytogenen
US7217510B2 (en) 2001-06-26 2007-05-15 Isis Pharmaceuticals, Inc. Methods for providing bacterial bioagent characterizing information
US8073627B2 (en) 2001-06-26 2011-12-06 Ibis Biosciences, Inc. System for indentification of pathogens
ATE323182T1 (de) * 2001-07-19 2006-04-15 Infectio Diagnostic Inc Universelle methode und zusammensetzung zur schnellen lysierung von zellen zur freisetzung von nukleinsäuren und ihre detektion
FR2829148B1 (fr) * 2001-09-06 2004-10-15 Univ Aix Marseille Ii Identification moleculaire des bacteries du genre staphylococcus
EP2722395B1 (de) 2001-10-15 2018-12-19 Bioarray Solutions Ltd Gemultiplexte Analyse polymorphischer Stellen durch gleichzeitige Abfrage und enzymvermittelte Detektion
US20040002080A1 (en) * 2001-12-14 2004-01-01 Creighton University Primers for use in detecting beta-lactamases
WO2003052128A1 (en) * 2001-12-19 2003-06-26 Quantibact A/S A method and a kit for determination of a microbial count
ES2223216B1 (es) * 2002-03-11 2006-04-16 Universidad De Sevilla Metodo para la deteccion e identificacion rapida de salmonella spp. mediante la reaccion en cadena de la polimerasa en tiempo real.
US6946267B2 (en) * 2002-03-13 2005-09-20 Dr. Chip Biotechnology Inc. Method for detecting Staphylococcus aureus
US7045291B2 (en) * 2002-05-17 2006-05-16 Creighton University Multiplex PCR for the detection of AmpC beta-lactamase genes
US7108976B2 (en) * 2002-06-17 2006-09-19 Affymetrix, Inc. Complexity management of genomic DNA by locus specific amplification
DE10244456A1 (de) * 2002-09-24 2004-04-15 Hain Lifescience Gmbh Verfahren zum Nachweis und Differenzierung von Bakterien
AU2003298655A1 (en) 2002-11-15 2004-06-15 Bioarray Solutions, Ltd. Analysis, secure access to, and transmission of array images
US7217519B1 (en) 2002-11-21 2007-05-15 The Board Of Trustees Of The University Of Arkansas Histoplasma capsulatum chitin synthase sequences and their use for detection of Histoplasma capsulatum and histoplasmosis
JP2006516193A (ja) 2002-12-06 2006-06-29 アイシス・ファーマシューティカルス・インコーポレーテッド ヒトおよび動物における病原体の迅速な同定方法
WO2004055205A2 (en) 2002-12-13 2004-07-01 Infectio Diagnostic (I.D.I.) Inc. Biological reagents and methods to verify the efficiency of sample preparation and nucleic acid amplification and/or detection
US8046171B2 (en) 2003-04-18 2011-10-25 Ibis Biosciences, Inc. Methods and apparatus for genetic evaluation
US8057993B2 (en) 2003-04-26 2011-11-15 Ibis Biosciences, Inc. Methods for identification of coronaviruses
US7964343B2 (en) 2003-05-13 2011-06-21 Ibis Biosciences, Inc. Method for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
US8158354B2 (en) 2003-05-13 2012-04-17 Ibis Biosciences, Inc. Methods for rapid purification of nucleic acids for subsequent analysis by mass spectrometry by solution capture
EP2327720A1 (de) * 2003-05-30 2011-06-01 Intercell AG Enterokokken-Antigene
CN1296488C (zh) * 2003-06-19 2007-01-24 中国药品生物制品检定所 药品中主要病原微生物的检测
DE10339609A1 (de) * 2003-08-28 2005-03-24 Forschungszentrum Karlsruhe Gmbh Oligonukleotid, Verfahren und System zur Detektion von Antibiotikaresistenz-vermittelnden Genen in Mikroorganismen mittels der Echtzeit-PCR
JP4714148B2 (ja) 2003-09-04 2011-06-29 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド 核酸検出アッセイ
US20070248954A1 (en) * 2003-09-10 2007-10-25 Creighton University Primers for Use in Detecting Beta-Lactamases
US8546082B2 (en) 2003-09-11 2013-10-01 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8097416B2 (en) 2003-09-11 2012-01-17 Ibis Biosciences, Inc. Methods for identification of sepsis-causing bacteria
US8394945B2 (en) 2003-09-11 2013-03-12 Ibis Biosciences, Inc. Compositions for use in identification of bacteria
US20050058985A1 (en) * 2003-09-12 2005-03-17 Dodgson Kirsty Jane Method and kit for identifying vancomycin-resistant enterococcus
US7927796B2 (en) 2003-09-18 2011-04-19 Bioarray Solutions, Ltd. Number coding for identification of subtypes of coded types of solid phase carriers
CA2539824C (en) 2003-09-22 2015-02-03 Xinwen Wang Surface immobilized polyelectrolyte with multiple functional groups capable of covalently bonding to biomolecules
EP1692298A4 (de) 2003-10-28 2008-08-13 Bioarray Solutions Ltd Optimierung der genexpressionsanalyse unter verwendung immobilisierter fängersonden
US7049077B2 (en) 2003-10-29 2006-05-23 Bioarray Solutions Ltd. Multiplexed nucleic acid analysis by fragmentation of double-stranded DNA
US8163895B2 (en) 2003-12-05 2012-04-24 Ibis Biosciences, Inc. Compositions for use in identification of orthopoxviruses
US7666592B2 (en) 2004-02-18 2010-02-23 Ibis Biosciences, Inc. Methods for concurrent identification and quantification of an unknown bioagent
US8119336B2 (en) 2004-03-03 2012-02-21 Ibis Biosciences, Inc. Compositions for use in identification of alphaviruses
US8168777B2 (en) 2004-04-29 2012-05-01 Human Genetic Signatures Pty. Ltd. Bisulphite reagent treatment of nucleic acid
CA2566860A1 (en) * 2004-05-20 2005-12-01 Bioarray Solutions Ltd. Genotyping of multiple loci with pcr for different loci amplification at different temperatures
EP1766659A4 (de) 2004-05-24 2009-09-30 Ibis Biosciences Inc Massenspektrometrie mit selektiver ionenfiltrierung durch digitalen schwellenvergleich
US20050266411A1 (en) 2004-05-25 2005-12-01 Hofstadler Steven A Methods for rapid forensic analysis of mitochondrial DNA
CN100374577C (zh) * 2004-06-25 2008-03-12 吴秉铨 用于检测b族链球菌特有序列的引物、短柄圆环探针、试剂盒及方法
US7811753B2 (en) 2004-07-14 2010-10-12 Ibis Biosciences, Inc. Methods for repairing degraded DNA
JP2008507296A (ja) * 2004-07-26 2008-03-13 ナノスフェアー インコーポレイテッド 混合培養物中でメチシリン耐性黄色ブドウ球菌とメチシリン感受性黄色ブドウ球菌とを区別する方法
US7848889B2 (en) 2004-08-02 2010-12-07 Bioarray Solutions, Ltd. Automated analysis of multiplexed probe-target interaction patterns: pattern matching and allele identification
US20080305966A1 (en) * 2004-08-02 2008-12-11 Regis Peytavi Capture Probe Design for Efficient Hybridisation
US7309589B2 (en) 2004-08-20 2007-12-18 Vironix Llc Sensitive detection of bacteria by improved nested polymerase chain reaction targeting the 16S ribosomal RNA gene and identification of bacterial species by amplicon sequencing
US7803580B2 (en) 2004-09-10 2010-09-28 Human Genetic Signatures Pty. Ltd. Amplification blocker comprising intercalating nucleic acids (INA) containing intercalating pseudonucleotides (IPN)
FR2875240B1 (fr) * 2004-09-16 2006-11-17 Biomerieux Sa Procede de detection de streptococcus agalactiae en utilisant l'activite alpha-glucosidase
ES2399054T3 (es) 2004-12-03 2013-03-25 Human Genetic Signatures Pty Ltd Métodos para simplificar ácidos nucleicos microbianos mediante modificación química de citosinas
WO2006088860A2 (en) * 2005-02-14 2006-08-24 Beattie Kenneth L Universal fingerprinting chips and uses thereof
US8084207B2 (en) 2005-03-03 2011-12-27 Ibis Bioscience, Inc. Compositions for use in identification of papillomavirus
US8182992B2 (en) 2005-03-03 2012-05-22 Ibis Biosciences, Inc. Compositions for use in identification of adventitious viruses
US20060210998A1 (en) * 2005-03-18 2006-09-21 Christiane Kettlitz Determination of antibiotic resistance in staphylococcus aureus
US7498136B2 (en) * 2005-03-18 2009-03-03 Eragen Biosciences, Inc. Methods for detecting multiple species and subspecies of Neisseria
US20060210999A1 (en) * 2005-03-18 2006-09-21 Verena Grimm Microarray and method for genotyping SHV beta lactamases
US20060246463A1 (en) * 2005-04-20 2006-11-02 Vevea Dirk N Methods and oligonucleotides for the detection of Salmonella SP., E coli 0157:H7, and Listeria monocytogenes
US20060240442A1 (en) * 2005-04-20 2006-10-26 Vevea Dirk N Methods and oligonucleotides for the detection of Salmonella SP., E coli 0157:H7, and Listeria monocytogenes
EP1883707B1 (de) 2005-05-26 2014-04-09 Human Genetic Signatures PTY Ltd Isothermische strangverdrängungsamplifikation unter verwendung von eine nichtreguläre base enthaltenden primern
US8486629B2 (en) 2005-06-01 2013-07-16 Bioarray Solutions, Ltd. Creation of functionalized microparticle libraries by oligonucleotide ligation or elongation
EP1904655A2 (de) 2005-07-21 2008-04-02 Isis Pharmaceuticals, Inc. Verfahren zur raschen identifizierung und quantifizierung von nukleinsäurevarianten
CA2621932A1 (en) 2005-09-14 2007-03-22 Human Genetic Signatures Pty Ltd Assay for hpv and methylated genomic dna targets to screen for cervical cancer
US11834720B2 (en) 2005-10-11 2023-12-05 Geneohm Sciences, Inc. Sequences for detection and identification of methicillin-resistant Staphylococcus aureus (MRSA) of MREJ types xi to xx
CN1814797B (zh) * 2005-12-02 2012-09-19 浙江大学 用于鉴定临床菌血症28种常见致病菌的特异性探针
EP2010679A2 (de) 2006-04-06 2009-01-07 Ibis Biosciences, Inc. Zusammensetzungen für die identifizierung von pilzen
KR100741375B1 (ko) 2006-07-24 2007-07-27 대한민국 기질확장형 β-락타마제의 신속분류를 위한 멀티플렉스PCR 기법 및 이를 위한 PCR 프라이머
AT504194B1 (de) * 2006-09-07 2008-07-15 Oesterr Rotes Kreuz Bakteriennachweis
JP5420412B2 (ja) 2006-09-14 2014-02-19 アイビス バイオサイエンシズ インコーポレイティッド 病原体の同定のための標的全ゲノム増幅方法
JP5680304B2 (ja) 2007-02-23 2015-03-04 アイビス バイオサイエンシズ インコーポレイティッド 迅速な法医学的dna分析法
WO2008124064A1 (en) 2007-04-04 2008-10-16 Network Biosystems, Inc. Plastic microfluidic separation and detection platforms
JP2010524454A (ja) 2007-04-19 2010-07-22 モレキュラー ディテクション インコーポレーテッド 抗生物質耐性細菌の検出および分析のための方法、組成物、およびキット
US9096849B2 (en) * 2007-05-21 2015-08-04 The United States Of America, As Represented By The Secretary Of The Navy Solid phase for capture of nucleic acids
US9598724B2 (en) 2007-06-01 2017-03-21 Ibis Biosciences, Inc. Methods and compositions for multiple displacement amplification of nucleic acids
US20090305252A1 (en) * 2007-06-05 2009-12-10 Yihong Li Methods and species-specific primers for detection and quantification of Streptococcus mutans and Streptococcus sanguinis in mixed bacterial samples
EP2183391A4 (de) * 2007-07-31 2010-10-27 Quest Diagnostics Invest Inc Nachweis von methicillin-resistenten und methicillin-sensitiven staphylococcus aureus-bakterien n biologischen proben
FR2922896B1 (fr) * 2007-10-30 2011-04-15 Biomerieux Sa Test biochimique pour confirmer la presence de l.monocytogenes
JP5431351B2 (ja) 2007-11-27 2014-03-05 ヒューマン ジェネティック シグネチャーズ ピーティーワイ リミテッド バイサルファイト修飾された核酸を増幅およびコピーするための酵素
FI20075976A0 (fi) 2007-12-31 2007-12-31 Finnzymes Oy Menetelmät ja oligonukleotidit utaretulehdusta aiheuttavien bakteerien osoittamiseksi
EP2344893B1 (de) 2008-09-16 2014-10-15 Ibis Biosciences, Inc. Mikroplatten-handhabungssysteme und verfahren
EP2349549B1 (de) 2008-09-16 2012-07-18 Ibis Biosciences, Inc. Mischpatronen, mischstationen und verwandte ausrüstungen, und system
WO2010033627A2 (en) 2008-09-16 2010-03-25 Ibis Biosciences, Inc. Sample processing units, systems, and related methods
US20100112643A1 (en) * 2008-11-04 2010-05-06 The Government Of The United States Of America, As Represented By The Secretary Of The Navy Method for direct capture of ribonucleic acid
GB0901707D0 (en) * 2009-02-03 2009-03-11 Q Chip Ltd Assay products, devices and method
WO2010093943A1 (en) 2009-02-12 2010-08-19 Ibis Biosciences, Inc. Ionization probe assemblies
JP5600880B2 (ja) * 2009-03-03 2014-10-08 東洋紡株式会社 改良された増幅試薬
WO2010104798A1 (en) 2009-03-08 2010-09-16 Ibis Biosciences, Inc. Bioagent detection methods
JP5593037B2 (ja) * 2009-03-12 2014-09-17 東洋水産株式会社 細菌測定用プライマーおよび細菌測定方法
WO2010114842A1 (en) 2009-03-30 2010-10-07 Ibis Biosciences, Inc. Bioagent detection systems, devices, and methods
US9550985B2 (en) 2009-06-15 2017-01-24 Netbio, Inc. Methods for forensic DNA quantitation
WO2011008972A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Systems for bioagent identification
WO2011008971A1 (en) 2009-07-17 2011-01-20 Ibis Biosciences, Inc. Lift and mount apparatus
WO2011014811A1 (en) 2009-07-31 2011-02-03 Ibis Biosciences, Inc. Capture primers and capture sequence linked solid supports for molecular diagnostic tests
EP3098325A1 (de) 2009-08-06 2016-11-30 Ibis Biosciences, Inc. Basenzusammensetzungen ohne massenbestimmung zur nukleinsäureerkennung
EP2473630B1 (de) * 2009-09-04 2017-11-08 QIAGEN GmbH Optimierte sonden und primer sowie verfahren zu deren verwendung zum nachweis, zum screening, zur isolation und zur sequenzierung von vancomycin-resistenzgenen und vancomycinresistenten enterokokken
ES2628739T3 (es) 2009-10-15 2017-08-03 Ibis Biosciences, Inc. Amplificación por desplazamiento múltiple
WO2011115840A2 (en) 2010-03-14 2011-09-22 Ibis Biosciences, Inc. Parasite detection via endosymbiont detection
JP2011223940A (ja) * 2010-04-21 2011-11-10 Asahi Breweries Ltd 偽陰性を排除するpcr検査方法およびそれに使用するプライマー
US8877909B2 (en) 2011-04-04 2014-11-04 Intelligent Medical Devices, Inc. Optimized oligonucleotides and methods of using same for the detection, isolation, amplification, quantitation, monitoring, screening, and sequencing of group B Streptococcus
CA2835620C (en) 2011-05-12 2021-02-23 Netbio, Inc. Methods and compositions for rapid multiplex amplification of str loci
WO2013033749A1 (en) 2011-09-07 2013-03-14 Human Genetic Signatures Pty Ltd Molecular detection assay
US20140242587A1 (en) * 2011-10-03 2014-08-28 University Of Florida Research Foundation, Inc. Rapid and Reliable Detection of Infectious Agents
US10167520B2 (en) 2011-12-06 2019-01-01 Scot E. Dowd Universal or broad range assays and multi-tag sample specific diagnostic process using non-optical sequencing
EP3074539B1 (de) * 2014-06-13 2018-01-10 Q-Linea AB Verfahren für den nachweis und die charakterisierung eines mikroorganismus
WO2016037051A1 (en) * 2014-09-04 2016-03-10 Theranos, Inc. Pathogen and antimicrobial resistance testing
CN104313167A (zh) * 2014-10-31 2015-01-28 广东医学院 快速鉴定b族链球菌兼检测其耐药性的引物及方法及引物应用
GB201507026D0 (en) 2015-04-24 2015-06-10 Linea Ab Q Medical sample transportation container
US11773455B2 (en) * 2015-09-09 2023-10-03 Psomagen, Inc. Method and system for microbiome-derived diagnostics and therapeutics infectious disease and other health conditions associated with antibiotic usage
CN105936931A (zh) * 2016-04-15 2016-09-14 山东畜牧兽医职业学院 一种荧光定量pcr检测养禽场肠杆菌科耐药基因的试剂盒及其检测方法
GB2554767A (en) 2016-04-21 2018-04-11 Q Linea Ab Detecting and characterising a microorganism
CA3042525A1 (en) * 2016-11-01 2018-05-11 Synthetic Biologics, Inc. Methods and compositions for attenuating antibiotic resistance
CN106480219A (zh) * 2016-12-15 2017-03-08 贵州大学 一种畜禽葡萄球菌大环内酯类药物耐药基因多重pcr检测试剂盒及使用方法
WO2022178142A1 (en) * 2021-02-17 2022-08-25 CAP Diagnostics, LLC, dba Pathnostics Methods and systems for determining suitability of compositions for inhibiting growth of polymicrobial samples
CN108456738B (zh) * 2017-05-15 2021-08-31 中国农业科学院兰州兽医研究所 一种TaqMan实时荧光定量PCR检测腐生葡萄球菌的方法
CN110129459B (zh) * 2018-02-05 2023-02-24 首都医科大学附属北京朝阳医院 一种用于检测眼内液中5种革兰氏阳性细菌的lamp引物组合及应用
CN108624704B (zh) * 2018-06-22 2021-08-10 上海孚清生物科技有限公司 一种荧光定量pcr探针技术联合检测沙眼衣原体、淋球菌、生殖道支原体的方法和试剂盒
SG11202102098WA (en) * 2018-09-03 2021-04-29 Visby Medical Inc Devices and methods for antibiotic susceptibility testing
CN109402277A (zh) * 2018-12-13 2019-03-01 博奥生物集团有限公司 用于快速检测粪肠球菌和屎肠球菌的lamp引物组合及应用
CN111693657A (zh) * 2019-03-15 2020-09-22 烟台欣和企业食品有限公司 评估调味品防腐能力的方法
US20220348986A1 (en) * 2019-06-19 2022-11-03 T2 Biosystems, Inc. Methods and compositions for comprehensive and high sensitivity detection of pathogens and drug resistance markers
CN110257540A (zh) * 2019-07-23 2019-09-20 中国疾病预防控制中心传染病预防控制所 检测变形杆菌属及奇异变形杆菌的pcr引物、引物组、探针及其试剂盒和检测方法
CN110951895B (zh) * 2019-12-24 2021-03-23 重庆市畜牧科学院 检测和区分奇异变形杆菌、普通变形杆菌和潘氏变形杆菌的系统和方法
CN111705118B (zh) * 2020-06-23 2023-01-10 宁夏医科大学总医院 一种基于靶基因高通量测序的血流感染检测试剂盒
CN112863606B (zh) * 2021-03-08 2022-07-26 杭州微数生物科技有限公司 细菌鉴定和分型分析基因组数据库及鉴定和分型分析方法
WO2022253741A1 (en) 2021-06-02 2022-12-08 Syngulon S.A. Cerein 7b bacteriocin for new application
EP4346870A1 (de) 2021-06-02 2024-04-10 Syngulon S.A. Bakteriocin zur neuen anwendung
CN113493847B (zh) * 2021-06-24 2022-04-19 北京工业大学 基于PMA高通量测序和PICRUSt的抗生素抗性基因及潜在宿主细菌的鉴定方法
CN113481310B (zh) * 2021-07-27 2023-05-05 河北农业大学 一种检测生姜腐烂病病原的lamp引物组、lamp试剂盒及其应用
CN113817810A (zh) * 2021-08-09 2021-12-21 宁波大学 一种检测发酵乳中乳酸菌的新型qPCR方法
WO2023049273A1 (en) * 2021-09-22 2023-03-30 Biomedit, Llc Methods for preserving healthy intestinal microbiome during growth promoter administration
WO2023081770A1 (en) * 2021-11-03 2023-05-11 T2 Biosystems, Inc. Methods and systems for amplification and detection in biological samples
CN114214399A (zh) * 2021-12-17 2022-03-22 山东博弘基因科技有限公司 一种解脲脲原体pcr检测试剂盒
WO2024036158A1 (en) * 2022-08-08 2024-02-15 North Carolina State University Methods and compositions for detecting the fungal pathogen ceratocystis fimbriata
CN116287330B (zh) * 2022-12-30 2023-12-05 中国科学院生态环境研究中心 一种可检测多种毒力基因的高通量实时荧光定量pcr芯片及其检测方法

Family Cites Families (53)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL71715A0 (en) * 1983-08-05 1984-09-30 Miles Lab Method,gene probes and test kit for detecting bacteria by nucleic acid hybridization
FR2567541B1 (fr) * 1984-07-13 1987-02-06 Pasteur Institut Sonde d'adn et procede pour la detection de " shigelles " et des souches entero-invasives de escherichia coli
FR2584419B1 (fr) * 1985-07-08 1987-11-13 Pasteur Institut Sonde et procede pour la detection de facteurs de resistance a l'erythromycine dans des cultures cellulaires, notamment bacteriennes
FR2599743B1 (fr) * 1986-06-10 1988-09-30 Pasteur Institut Fragment d'adn comprenant au moins une partie d'un gene de resistance a l'erythromycine, son procede d'obtention et ses applications biochimiques
EP0277237A4 (de) * 1986-07-10 1990-02-22 Toray Industries Verfahren, sowie sonde zum nachweis von bakterien in mustern.
DE3752172T3 (de) * 1986-11-24 2008-04-10 Gen-Probe Inc., San Diego Nukleinsäuresonden zum Nachweis und/oder zur Quantifizierung von nicht-viralen Organismen
DE3718591A1 (de) * 1987-06-03 1988-12-15 Behringwerke Ag Aeusseres membranprotein f von pseudomonas aeruginosa
US5089386A (en) 1987-09-11 1992-02-18 Gene-Trak Systems Test for listeria
JP2801322B2 (ja) * 1988-01-13 1998-09-21 インスティチュート・パスツール 溶血性リステリア属に特異的なdnaプローブ
CA1339261C (en) 1988-04-15 1997-08-12 Rudi Rossau Hybridization probes for detecting neisseria strains
US5523205A (en) * 1988-08-02 1996-06-04 Institut Pasteur DNA probes specific for hemolytic listeria
US5084565A (en) * 1988-08-18 1992-01-28 Gene-Trak Systems Probes for the specific detection of escherichia coli and shigella
FR2636075B1 (fr) * 1988-09-07 1991-11-15 Biotechnologie Ste Europ Procede de detection des bacteries, levures, parasites et autres eucaryotes, notamment dans les produits alimentaires
US5041372A (en) * 1988-11-02 1991-08-20 The United States Of America As Represented By The Department Of Health And Human Services Probe to identify enteroinvasive E. coli and Shigella species
US5030556A (en) * 1989-03-30 1991-07-09 Danielle Beaulieu Species-specific DNNA probe for the detection of Branhamella catarrhalis
WO1990014444A1 (en) * 1989-05-23 1990-11-29 Gene-Trak Systems Nucleic acid probes for the detection of staphylococcus aureus
JP3258658B2 (ja) * 1989-05-31 2002-02-18 ジーン−トラック・システムス ユニバーサル ユーバクテリア核酸プローブ及び方法
DE3925613A1 (de) 1989-06-22 1991-01-03 Boehringer Mannheim Gmbh Neisseria-spezifische dna-sonde
US5334501A (en) * 1989-07-11 1994-08-02 Microprobe Corporation Quantification of bacteria using a nucleic acid hybridization assay
NL9002157A (nl) * 1989-11-27 1991-06-17 U Gene Research Bv Dna fragmenten en daarop gebaseerde dna-probes en primers.
CA2033718A1 (en) * 1990-01-19 1991-07-20 Ronald M. Atlas Process for detection of water-borne microbial pathogens and indicators of human fecal contamination in water samples and kits therefor
CA2075186A1 (en) * 1990-02-02 1991-08-03 Rudi Rossau Hybridization probes for the detection of branhamella catarrhalis strains
EP0452596A1 (de) * 1990-04-18 1991-10-23 N.V. Innogenetics S.A. Hibridizierungssonden aus dem Abstandsbereich zwischen den 16S- und 23S-rRNA-Genen und Nachweis von nichtviralen Mikroorganismen
SE466259B (sv) * 1990-05-31 1992-01-20 Arne Forsgren Protein d - ett igd-bindande protein fraan haemophilus influenzae, samt anvaendning av detta foer analys, vacciner och uppreningsaendamaal
ES2168250T3 (es) * 1990-10-05 2002-06-16 Hoffmann La Roche Metodos y reactivos para la identificacion de bacterias gram negativas.
EP0571538B1 (de) * 1991-02-15 1998-07-08 The Uab Research Foundation Strukturgen von pneumokokken-protein
US5980909A (en) * 1991-02-15 1999-11-09 Uab Research Foundation Epitopic regions of pneumococcal surface protein A
US5472843A (en) * 1991-04-25 1995-12-05 Gen-Probe Incorporated Nucleic acid probes to Haemophilus influenzae
US5232831A (en) * 1991-06-28 1993-08-03 Gen-Probe Incorporated Nucleic acid probes to streptococcus pyogenes
CA2116543C (en) * 1991-07-31 2007-10-02 Kay S. Greisen Methods and reagents for detection of bacteria in cerebrospinal fluid
JPH0549477A (ja) * 1991-08-05 1993-03-02 Wakunaga Pharmaceut Co Ltd スタフイロコツカス属細菌類の検出
CA2075423A1 (en) * 1991-08-13 1993-02-14 Paul Luther Skatrud Rapid method for detection of methicillin resistant staphylococci
US5292874A (en) * 1991-09-04 1994-03-08 Gen-Probe Incorporated Nucleic acid probes to Staphylococcus aureus
FR2685334B1 (fr) * 1991-12-23 1995-05-05 Bio Merieux Polypeptides contenant des sequences caracteristiques de pyrrolidone carboxylyl peptidases, polynucleotides contenant une sequence codant pour de tels polypeptides, et leur utilisation.
JPH0690798A (ja) * 1992-02-05 1994-04-05 Toagosei Chem Ind Co Ltd 黄色ブドウ球菌検出用プローブ及び検出方法
FR2687168B1 (fr) * 1992-02-10 1994-03-25 Bio Merieux Fragment de l'adn genomique de streptococcus pneumoniae, sonde d'hybridation, amorce d'amplification, reactif et procede de detection de streptococcus pneumoniae.
JPH0654700A (ja) * 1992-05-19 1994-03-01 Mitsui Toatsu Chem Inc 耐性菌の高感度検出法
EP1167543B1 (de) * 1992-07-07 2005-10-19 Fuso Pharmaceutical Industries Ltd. Sonde zur Diagnose einer ansteckenden Krankheit verursacht durch Staphylococcus Epidermidis
IL106273A0 (en) * 1992-07-17 1993-11-15 Res Dev Foundation Rapid detection of biopolymers in stained specimens
JPH06165681A (ja) * 1992-12-02 1994-06-14 Toyobo Co Ltd メチシリン耐性ブドウ球菌検出用オリゴヌクレオチド、メチシリン耐性ブドウ球菌の検出法および検出用試薬キット
FR2699539B1 (fr) * 1992-12-18 1995-02-17 Pasteur Institut Protéine conférant une résistance de type inductible, à des glycopeptides, notamment chez des bactéries à gram-positif. Séquence de nucléotides codant pour cette protéine.
DE69433107T2 (de) * 1993-06-23 2004-07-08 Beckman Coulter, Inc., Fullerton Rekombinante dnase b aus streptococcus pyogenes
JP3499263B2 (ja) * 1993-09-03 2004-02-23 株式会社紀文食品 クレブシエラ属菌の検出及び塩基配列
US5426026A (en) * 1993-09-15 1995-06-20 University Of Pittsburgh PCR identification of four medically important candida species using one primer pair and four species-specific probes
US5712118A (en) * 1993-09-29 1998-01-27 Research Foundation Of State University Of New York Vaccine for branhamella catarrhalis
JP3525475B2 (ja) * 1994-01-10 2004-05-10 恵 河野 新規な ’mecAタンパク質、それをコードするDNA、およびそれを用いたメチシリン耐性黄色ブドウ球菌の検出方法
US5582978A (en) * 1994-01-21 1996-12-10 Amoco Corporation Nucleic acid probes for the detection of Haemophilus influenzae
ATE423853T1 (de) * 1994-06-24 2009-03-15 Innogenetics Nv Gleichzeitiger nachweis, identifizierung und differenzierung von mykobakterium spezies unter verwendung eines hybridisierungs-assays
WO1996002648A1 (en) * 1994-07-19 1996-02-01 American Cyanamid Company Lkp pilin structural genes and operon of nontypable haemophilus influenzae
US6001564A (en) * 1994-09-12 1999-12-14 Infectio Diagnostic, Inc. Species specific and universal DNA probes and amplification primers to rapidly detect and identify common bacterial pathogens and associated antibiotic resistance genes from clinical specimens for routine diagnosis in microbiology laboratories
US5668263A (en) * 1994-12-16 1997-09-16 Smithkline Beecham Corporation Conserved yeast nucleic acid sequences
US5827515A (en) * 1995-08-30 1998-10-27 Sandoz Ltd. Bacillus thuringiensis sporulation gene
US6737248B2 (en) * 1996-01-05 2004-05-18 Human Genome Sciences, Inc. Staphylococcus aureus polynucleotides and sequences

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CA2715575C (en) 2012-12-18
DK0943009T3 (da) 2009-10-05
WO1998020157A3 (en) 1998-08-13
EP2336364A1 (de) 2011-06-22
CA2789369A1 (en) 1998-05-14
EP2345746B1 (de) 2014-10-15
CA2270281C (en) 2010-12-21
EP2336364B1 (de) 2015-04-08
JP2001504330A (ja) 2001-04-03
EP2128268B1 (de) 2012-04-04
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