DE69736185T2 - Zusammensetzung eines polynucleotid-impfstoffes für katzen - Google Patents

Zusammensetzung eines polynucleotid-impfstoffes für katzen Download PDF

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Publication number
DE69736185T2
DE69736185T2 DE69736185T DE69736185T DE69736185T2 DE 69736185 T2 DE69736185 T2 DE 69736185T2 DE 69736185 T DE69736185 T DE 69736185T DE 69736185 T DE69736185 T DE 69736185T DE 69736185 T2 DE69736185 T2 DE 69736185T2
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Prior art keywords
vaccine
plasmid
promoter
virus
vivo
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Expired - Lifetime
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DE69736185T
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German (de)
English (en)
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DE69736185D1 (de
Inventor
Jean-Christophe Audonnet
Annabelle Bouchardon
Philippe Baudu
Michel Riviere
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Boehringer Ingelheim Animal Health France SAS
Boehringer Ingelheim Animal Health USA Inc
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Merial SAS
Merial Inc
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    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
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    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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  • Health & Medical Sciences (AREA)
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  • Virology (AREA)
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  • Animal Behavior & Ethology (AREA)
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  • Microbiology (AREA)
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  • General Engineering & Computer Science (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • Pulmonology (AREA)
  • Plant Pathology (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
DE69736185T 1996-07-19 1997-07-15 Zusammensetzung eines polynucleotid-impfstoffes für katzen Expired - Lifetime DE69736185T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
FR9609337A FR2751223B1 (fr) 1996-07-19 1996-07-19 Formule de vaccin polynucleotidique felin
FR9609337 1996-07-19
PCT/FR1997/001315 WO1998003660A1 (fr) 1996-07-19 1997-07-15 Formule de vaccin polynucleotidique felin

Publications (2)

Publication Number Publication Date
DE69736185D1 DE69736185D1 (de) 2006-08-03
DE69736185T2 true DE69736185T2 (de) 2007-04-19

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Application Number Title Priority Date Filing Date
DE69736185T Expired - Lifetime DE69736185T2 (de) 1996-07-19 1997-07-15 Zusammensetzung eines polynucleotid-impfstoffes für katzen

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US (2) US6348196B1 (enExample)
EP (1) EP0934416B1 (enExample)
JP (1) JP2001500112A (enExample)
KR (1) KR100687509B1 (enExample)
AR (1) AR007861A1 (enExample)
AU (1) AU3699297A (enExample)
BR (2) BR9715228B1 (enExample)
CA (1) CA2261345C (enExample)
CZ (2) CZ298613B6 (enExample)
DE (1) DE69736185T2 (enExample)
FR (1) FR2751223B1 (enExample)
NZ (1) NZ333781A (enExample)
PL (1) PL191551B1 (enExample)
RU (1) RU2312676C2 (enExample)
WO (1) WO1998003660A1 (enExample)
ZA (1) ZA976286B (enExample)

Families Citing this family (45)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2223029A1 (en) 1997-02-12 1998-08-12 Akzo Nobel Nv Canine parvovirus dna vaccines
EP0863151A1 (en) * 1997-02-12 1998-09-09 Akzo Nobel N.V. "Canine parvovirus dna vaccines"
US6770282B1 (en) * 1998-10-23 2004-08-03 Heska Corporation Cationic lipid-mediated enhancement of nucleic acid immunization of cats
FR2794648B1 (fr) * 1999-06-10 2003-03-07 Merial Sas Vaccins adn pour animaux de compagnie et de sport
BR0011732B1 (pt) * 1999-06-10 2014-02-04 Vacinas de dna para animais de companhia e de esporte
EP1074625A3 (en) * 1999-06-14 2002-01-02 Pfizer Products Inc. DNA vaccine against feline immunodeficiency virus
WO2001004280A2 (de) * 1999-07-08 2001-01-18 Mologen Forschungs-, Entwicklungs- Und Vertriebs Gmbh Impfstoff gegen infektionen mit lentiviren, wie dem felinen immunschwäche-virus der katze
FR2796396A1 (fr) * 1999-07-16 2001-01-19 Merial Sas Gene de calicivirus felin et vaccin recombine les incorporant
US6541458B1 (en) 1999-07-16 2003-04-01 Merial Feline calicivirus genes and vaccines in particular recombinant vaccines
FR2796397B1 (fr) * 1999-07-16 2006-09-01 Merial Sas Genes de calicivirus felin et vaccins notamment vaccins recombines
US7078388B2 (en) 2000-01-21 2006-07-18 Merial DNA vaccines for farm animals, in particular bovines and porcines
FR2829498B1 (fr) * 2001-09-11 2003-11-28 Merial Sas Igf-1 comme adjuvant de vaccin felin, notamment contre les retrovirus felins
WO2004028562A2 (de) * 2002-09-23 2004-04-08 Mologen Ag Impfstoff gegen infektionen mit onkoviren, wie dem felinen leukosevirus der katze
EP2390352A1 (en) 2003-03-18 2011-11-30 Quantum Genetics Ireland Limited Systems and methods for improving protein and milk production of dairy herds
US7468273B2 (en) 2003-05-01 2008-12-23 Meial Limited Canine GHRH gene, polypeptides and methods of use
MXPA06005424A (es) 2003-11-13 2007-01-25 Univ Georgia Res Found Metodos para caracterizar virus de enfermedad bursal infecciosa.
CA2556911C (en) 2004-02-19 2013-07-30 The Governors Of The University Of Alberta Leptin promoter polymorphisms and uses thereof
ES2343270T3 (es) 2005-04-25 2010-07-27 Merial Ltd. Vacunas contra el virus nipah.
US20080241184A1 (en) 2005-08-25 2008-10-02 Jules Maarten Minke Canine influenza vaccines
EP1951751B1 (en) 2005-11-14 2017-11-01 Merial, Inc. Gene therapy for renal failure
US7771995B2 (en) 2005-11-14 2010-08-10 Merial Limited Plasmid encoding human BMP-7
US7862821B2 (en) 2006-06-01 2011-01-04 Merial Limited Recombinant vaccine against bluetongue virus
UA100692C2 (ru) 2007-05-02 2013-01-25 Мериал Лимитед Днк-плазмиды, имеющие повышенную экспрессию и стабильность
US8871220B2 (en) 2009-04-03 2014-10-28 Merial Limited Newcastle disease virus vectored avian vaccines
US8986706B2 (en) 2010-08-31 2015-03-24 Merial, Inc. Newcastle disease virus vectored herpesvirus vaccines
WO2012090073A2 (en) 2010-12-30 2012-07-05 The Netherlands Cancer Institute Methods and compositions for predicting chemotherapy sensitivity
WO2012138789A2 (en) 2011-04-04 2012-10-11 Netherlands Cancer Institute Methods and compositions for predicting resistance to anticancer treatment
US20140296248A1 (en) 2011-04-04 2014-10-02 Stichting het Nederlands Kanker Instiuut-Antoni van Leeuwenhoek ziekenhuis Methods and compositions for predicting resistance to anticancer treatment
US9216213B2 (en) 2011-04-20 2015-12-22 Merial, Inc. Adjuvanted rabies vaccine with improved viscosity profile
JP6407714B2 (ja) 2011-04-25 2018-10-17 アドヴァンスド バイオサイエンス ラボラトリーズ インコーポレイテッド 短縮型ｈｉｖエンベロープタンパク質（ｅｎｖ）、前記に関連する方法及び組成物
ES2674439T3 (es) 2011-06-01 2018-06-29 Merial, Inc. Administración sin aguja de vacunas contra el VSRRP
CA2844927C (en) 2011-08-12 2017-10-31 Merial Limited Vacuum-assisted preservation of biological products, in particular of vaccines
WO2013093629A2 (en) 2011-12-20 2013-06-27 Netherlands Cancer Institute Modular vaccines, methods and compositions related thereto
WO2013138776A1 (en) 2012-03-16 2013-09-19 Merial Limited Novel methods for providing long-term protective immunity against rabies in animals, based upon administration of replication-deficient flavivirus expressing rabies g
US9556419B2 (en) 2013-03-12 2017-01-31 Merial Inc. Reverse genetics Schmallenberg virus vaccine compositions, and methods of use thereof
AU2015343369B2 (en) 2014-11-03 2018-11-22 Georgia Tech Research Corporation Methods of using microneedle vaccine formulations to elicit in animals protective immunity against rabies virus
RU2586504C1 (ru) * 2015-04-29 2016-06-10 Федеральное государственное бюджетное образовательное учреждение высшего профессионального образования "Саратовский государственный аграрный университет имени Н.И. Вавилова" Набор синтетических олигонуклеотидных праймеров и способ его применения для индикации вирусов иммунодефицита и лейкемии кошек в клиническом материале методом мультиплексной полимеразной цепной реакции
PH12017502380B1 (en) 2015-06-23 2022-10-26 Merial Inc Prrsv minor protein-containing recombinant viral vectors and methods of making and use thereof
FR3044016A1 (fr) * 2015-11-24 2017-05-26 Glaxosmithkline Ip Dev Ltd Lignees cellulaires stables pour la production retrovirale
KR102067352B1 (ko) * 2015-11-24 2020-01-16 글락소스미스클라인 인털렉츄얼 프로퍼티 디벨로프먼트 리미티드 레트로바이러스 생산을 위한 일시적인 형질감염 방법
CN112921122A (zh) * 2021-03-26 2021-06-08 广西大学 猫常见病毒多重pcr快速检测试剂盒及其引物组
CN112921123B (zh) * 2021-04-06 2022-11-04 中国农业科学院哈尔滨兽医研究所（中国动物卫生与流行病学中心哈尔滨分中心） 快速检测猫杯状病毒的方法及检测用引物和试剂盒
CN115894716B (zh) * 2022-11-23 2024-02-09 华中农业大学 一种重组融合蛋白纳米颗粒及其制备方法
CN116218889A (zh) * 2022-12-13 2023-06-06 浙江大学 一种表达猫细小病毒VP2蛋白的mRNA疫苗及其制备方法
CN116121282B (zh) * 2023-01-10 2023-09-22 浙江大学 一种表达猫疱疹病毒蛋白的mRNA疫苗及其制备方法

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5631154A (en) * 1988-06-10 1997-05-20 Therion Biologics, Incorporated Self assembled, defective, non-self-propagating lentivirus particles
HUT54733A (en) * 1989-07-12 1991-03-28 Duphar Int Res Process for producing new, antigenically active proteins and peptides, as well as feline infectious peritonitis virus (fipv) vaccines
ES2069742T3 (es) * 1989-07-21 1995-05-16 Upjohn Co Proteina de la capsida del calicivirus felino y secuencia nucleotida.
US5665362A (en) * 1990-09-25 1997-09-09 Cantab Pharmaceuticals Research Limited Viral vaccines
JPH07504897A (ja) * 1992-02-18 1995-06-01 パーヘリオン　コーポレーション ネコ感染性腹膜炎ワクチンおよび調製方法
WO1994006921A1 (en) * 1992-09-21 1994-03-31 Viagene, Inc. Recombinant retroviral vector against felv and/or fiv
GB2282601B (en) * 1993-09-16 1998-04-15 Solvay Antigenically-active proteins/polypeptides and coronavirus vaccines containing the same
US6348449B1 (en) * 1993-09-21 2002-02-19 The Trustees Of The University Of Pennsylvania Methods of inducing mucosal immunity
TW377373B (en) * 1993-09-22 1999-12-21 Wyeth Corp Recombinant raccoon pox viruses and their use as an effective vaccine against feline infectious peritonitis virus disease
ATE475668T1 (de) * 1994-01-27 2010-08-15 Univ Massachusetts Medical Immunisierung durch impfung von dns transkriptionseinheit
US5529780A (en) * 1994-03-30 1996-06-25 Virogenetics Corporation Nucleotide and amino acid sequences of canine herpesvirus gB and gC
US5833993A (en) * 1994-04-29 1998-11-10 Pharmacia & Upjohn Company Feline immunodeficiency virus vaccine
FR2724385B1 (fr) * 1994-08-29 1996-12-13 Rhone Merieux Vaccin de la peritonite infectieuse feline.

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EP0934416A1 (fr) 1999-08-11
AR007861A1 (es) 1999-11-24
DE69736185D1 (de) 2006-08-03
US20030017172A1 (en) 2003-01-23
RU2312676C2 (ru) 2007-12-20
CA2261345A1 (en) 1998-01-29
BR9710497A (pt) 1999-08-17
CZ304126B6 (cs) 2013-11-06
KR20000065257A (ko) 2000-11-06
CA2261345C (en) 2010-09-14
PL191551B1 (pl) 2006-06-30
NZ333781A (en) 2000-09-29
BR9710497B1 (pt) 2011-04-05
FR2751223A1 (fr) 1998-01-23
CZ298613B6 (cs) 2007-11-21
RU2002132832A (ru) 2005-01-20
BR9715228B1 (pt) 2011-10-04
US6348196B1 (en) 2002-02-19
EP0934416B1 (fr) 2006-06-21
PL331247A1 (en) 1999-07-05
US7534559B2 (en) 2009-05-19
CZ15999A3 (cs) 1999-06-16
KR100687509B1 (ko) 2007-10-12
FR2751223B1 (fr) 1998-12-04
ZA976286B (en) 1999-01-19

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