DE69617431T2 - Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalator - Google Patents
Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalatorInfo
- Publication number
- DE69617431T2 DE69617431T2 DE69617431T DE69617431T DE69617431T2 DE 69617431 T2 DE69617431 T2 DE 69617431T2 DE 69617431 T DE69617431 T DE 69617431T DE 69617431 T DE69617431 T DE 69617431T DE 69617431 T2 DE69617431 T2 DE 69617431T2
- Authority
- DE
- Germany
- Prior art keywords
- dosing
- inhaler
- powder
- cartridge
- powder cartridge
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
- 239000000843 powder Substances 0.000 title claims description 373
- 239000003814 drug Substances 0.000 claims description 113
- 229940079593 drug Drugs 0.000 claims description 95
- 238000003860 storage Methods 0.000 claims description 40
- 238000003825 pressing Methods 0.000 claims description 11
- 239000011888 foil Substances 0.000 claims description 10
- 230000015572 biosynthetic process Effects 0.000 claims description 6
- 230000000007 visual effect Effects 0.000 claims description 6
- 238000011010 flushing procedure Methods 0.000 claims description 5
- 230000005484 gravity Effects 0.000 claims description 3
- 239000003795 chemical substances by application Substances 0.000 claims description 2
- 239000012815 thermoplastic material Substances 0.000 claims 1
- 238000013461 design Methods 0.000 description 24
- 238000000034 method Methods 0.000 description 15
- 230000008569 process Effects 0.000 description 15
- 239000002245 particle Substances 0.000 description 9
- 230000000694 effects Effects 0.000 description 8
- 239000004033 plastic Substances 0.000 description 8
- 229920003023 plastic Polymers 0.000 description 8
- 238000010926 purge Methods 0.000 description 7
- 239000004480 active ingredient Substances 0.000 description 6
- 230000007246 mechanism Effects 0.000 description 6
- -1 polyethylene Polymers 0.000 description 5
- 230000002028 premature Effects 0.000 description 5
- 230000009471 action Effects 0.000 description 4
- 239000006185 dispersion Substances 0.000 description 4
- 238000004519 manufacturing process Methods 0.000 description 4
- 239000000203 mixture Substances 0.000 description 4
- 239000002985 plastic film Substances 0.000 description 4
- 229920006255 plastic film Polymers 0.000 description 4
- 238000011282 treatment Methods 0.000 description 4
- 239000004743 Polypropylene Substances 0.000 description 3
- 239000004793 Polystyrene Substances 0.000 description 3
- 230000005540 biological transmission Effects 0.000 description 3
- 238000009472 formulation Methods 0.000 description 3
- 238000003780 insertion Methods 0.000 description 3
- 230000037431 insertion Effects 0.000 description 3
- 229920001155 polypropylene Polymers 0.000 description 3
- 229920002223 polystyrene Polymers 0.000 description 3
- 239000005538 withdrawn drug Substances 0.000 description 3
- 239000004698 Polyethylene Substances 0.000 description 2
- 229920000122 acrylonitrile butadiene styrene Polymers 0.000 description 2
- 239000000853 adhesive Substances 0.000 description 2
- 230000001070 adhesive effect Effects 0.000 description 2
- 208000006673 asthma Diseases 0.000 description 2
- 210000000621 bronchi Anatomy 0.000 description 2
- 230000008859 change Effects 0.000 description 2
- 239000011362 coarse particle Substances 0.000 description 2
- 238000000354 decomposition reaction Methods 0.000 description 2
- 238000006073 displacement reaction Methods 0.000 description 2
- 238000001746 injection moulding Methods 0.000 description 2
- 230000003993 interaction Effects 0.000 description 2
- 230000002093 peripheral effect Effects 0.000 description 2
- 229920000058 polyacrylate Polymers 0.000 description 2
- 229920000515 polycarbonate Polymers 0.000 description 2
- 239000004417 polycarbonate Substances 0.000 description 2
- 229920000573 polyethylene Polymers 0.000 description 2
- 229920002635 polyurethane Polymers 0.000 description 2
- 239000004814 polyurethane Substances 0.000 description 2
- 239000011164 primary particle Substances 0.000 description 2
- 230000001225 therapeutic effect Effects 0.000 description 2
- 229920001169 thermoplastic Polymers 0.000 description 2
- 239000004416 thermosoftening plastic Substances 0.000 description 2
- 230000001960 triggered effect Effects 0.000 description 2
- 208000014085 Chronic respiratory disease Diseases 0.000 description 1
- 241001484259 Lacuna Species 0.000 description 1
- 230000004913 activation Effects 0.000 description 1
- 239000008186 active pharmaceutical agent Substances 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 230000000903 blocking effect Effects 0.000 description 1
- 238000004140 cleaning Methods 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 238000007906 compression Methods 0.000 description 1
- 230000006835 compression Effects 0.000 description 1
- 238000011109 contamination Methods 0.000 description 1
- 230000003111 delayed effect Effects 0.000 description 1
- 230000008021 deposition Effects 0.000 description 1
- 229940088679 drug related substance Drugs 0.000 description 1
- 230000009977 dual effect Effects 0.000 description 1
- 239000010419 fine particle Substances 0.000 description 1
- 238000011866 long-term treatment Methods 0.000 description 1
- 210000004072 lung Anatomy 0.000 description 1
- 229910052751 metal Inorganic materials 0.000 description 1
- 239000002184 metal Substances 0.000 description 1
- 229910001092 metal group alloy Inorganic materials 0.000 description 1
- 150000002739 metals Chemical class 0.000 description 1
- 230000003287 optical effect Effects 0.000 description 1
- 238000004806 packaging method and process Methods 0.000 description 1
- 229920000642 polymer Polymers 0.000 description 1
- 238000002360 preparation method Methods 0.000 description 1
- 230000009467 reduction Effects 0.000 description 1
- 230000002040 relaxant effect Effects 0.000 description 1
- 230000003068 static effect Effects 0.000 description 1
- 238000012546 transfer Methods 0.000 description 1
- 230000007704 transition Effects 0.000 description 1
- 238000009423 ventilation Methods 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M11/00—Sprayers or atomisers specially adapted for therapeutic purposes
- A61M11/001—Particle size control
- A61M11/002—Particle size control by flow deviation causing inertial separation of transported particles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0065—Inhalators with dosage or measuring devices
- A61M15/0068—Indicating or counting the number of dispensed doses or of remaining doses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0096—Hindering inhalation before activation of the dispenser
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M15/00—Inhalators
- A61M15/0091—Inhalators mechanically breath-triggered
- A61M15/0095—Preventing manual activation in absence of inhalation
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61M—DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY; DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROM THE BODY; DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR
- A61M2202/00—Special media to be introduced, removed or treated
- A61M2202/06—Solids
- A61M2202/064—Powder
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Animal Behavior & Ethology (AREA)
- Anesthesiology (AREA)
- Public Health (AREA)
- Heart & Thoracic Surgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pulmonology (AREA)
- Biophysics (AREA)
- Medical Preparation Storing Or Oral Administration Devices (AREA)
- Containers And Packaging Bodies Having A Special Means To Remove Contents (AREA)
- External Artificial Organs (AREA)
- Infusion, Injection, And Reservoir Apparatuses (AREA)
- Basic Packing Technique (AREA)
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE69617431T DE69617431T2 (de) | 1995-06-21 | 1996-06-03 | Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalator |
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE19522415A DE19522415C2 (de) | 1995-06-21 | 1995-06-21 | Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone |
| DE1995122416 DE19522416C2 (de) | 1995-06-21 | 1995-06-21 | Vorrichtung zum Dispergieren von Pulver in einem Luftstrom zur Verwendung mit Pulver-Inhalatoren |
| DE69617431T DE69617431T2 (de) | 1995-06-21 | 1996-06-03 | Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalator |
| PCT/EP1996/002396 WO1997000703A1 (en) | 1995-06-21 | 1996-06-03 | Pharmaceutical powder cartridge with integrated metering device and inhaler for powdered medicaments |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69617431D1 DE69617431D1 (de) | 2002-01-10 |
| DE69617431T2 true DE69617431T2 (de) | 2002-08-01 |
Family
ID=26016125
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69617431T Expired - Lifetime DE69617431T2 (de) | 1995-06-21 | 1996-06-03 | Arzneipulverkartusche mit integrierter dosiereinrichtung, sowie pulverinhalator |
Country Status (29)
| Country | Link |
|---|---|
| US (2) | US5840279A (enExample) |
| EP (1) | EP0837710B1 (enExample) |
| JP (1) | JP3299971B2 (enExample) |
| KR (1) | KR100269060B1 (enExample) |
| CN (2) | CN1181896C (enExample) |
| AR (1) | AR002534A1 (enExample) |
| AT (1) | ATE209518T1 (enExample) |
| AU (1) | AU719449B2 (enExample) |
| BR (1) | BR9608997A (enExample) |
| CA (2) | CA2378713C (enExample) |
| CZ (2) | CZ294700B6 (enExample) |
| DE (1) | DE69617431T2 (enExample) |
| DK (1) | DK0837710T3 (enExample) |
| ES (1) | ES2168488T3 (enExample) |
| HR (1) | HRP960294B1 (enExample) |
| HU (1) | HU220227B (enExample) |
| ID (1) | ID17207A (enExample) |
| IL (1) | IL122494A (enExample) |
| IN (1) | IN189233B (enExample) |
| NO (1) | NO314879B1 (enExample) |
| NZ (2) | NZ502870A (enExample) |
| PL (2) | PL182715B1 (enExample) |
| PT (1) | PT837710E (enExample) |
| RU (1) | RU2162346C2 (enExample) |
| SI (1) | SI9620081B (enExample) |
| SK (1) | SK284303B6 (enExample) |
| TR (1) | TR199701665T1 (enExample) |
| TW (1) | TW325409B (enExample) |
| WO (1) | WO1997000703A1 (enExample) |
Families Citing this family (178)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP3299971B2 (ja) * | 1995-06-21 | 2002-07-08 | アスタ メディカ アクチエンゲゼルシャフト | 一体的に形成された調量装置を備えた薬用粉末カートリッジおよび粉末薬剤吸入器 |
| SE9700940D0 (sv) * | 1997-03-14 | 1997-03-14 | Astra Ab | Powder inhaler IV |
| US6293279B1 (en) | 1997-09-26 | 2001-09-25 | Trudell Medical International | Aerosol medication delivery apparatus and system |
| US6345617B1 (en) | 1997-09-26 | 2002-02-12 | 1263152 Ontario Inc. | Aerosol medication delivery apparatus and system |
| US6257233B1 (en) | 1998-06-04 | 2001-07-10 | Inhale Therapeutic Systems | Dry powder dispersing apparatus and methods for their use |
| US9006175B2 (en) | 1999-06-29 | 2015-04-14 | Mannkind Corporation | Potentiation of glucose elimination |
| ES2165768B1 (es) | 1999-07-14 | 2003-04-01 | Almirall Prodesfarma Sa | Nuevos derivados de quinuclidina y composiciones farmaceuticas que los contienen. |
| DE19961300A1 (de) * | 1999-12-18 | 2001-06-21 | Asta Medica Ag | Vorratssystem für Arzneimittel in Pulverform und damit ausgestatteter Inhalator |
| BR0108730A (pt) * | 2000-02-28 | 2002-11-05 | Vectura Ltd | Sistema, dispositivo e método para administração de uma droga, bocal de um dispositivo de administração de droga, dispositivo para administração de doses unitárias múltiplas de uma droga, métodos para preparação de um sistema de administração de droga e de uma formulação de droga e para tratamento de um paciente que necessita de doses múltiplas de uma droga, formulação de droga e multiparticulados |
| FI20000810A0 (fi) * | 2000-04-06 | 2000-04-06 | Orion Yhtymae Oyj | Jauheinhalaattori |
| WO2001076671A2 (en) | 2000-04-11 | 2001-10-18 | Trudell Medical International | Aerosol delivery apparatus with positive expiratory pressure capacity |
| PE20020074A1 (es) | 2000-06-23 | 2002-02-05 | Norton Healthcare Ltd | Sistema dosificador para inhalador de medicamento |
| US6629524B1 (en) * | 2000-07-12 | 2003-10-07 | Ponwell Enterprises Limited | Inhaler |
| JP4412901B2 (ja) * | 2001-03-02 | 2010-02-10 | ウッドウェルディング・アクチェンゲゼルシャフト | 組織部、特に骨格部への接続を作製するためのインプラント、ならびにインプラントの埋込のための装置および方法 |
| US6698422B2 (en) | 2001-03-12 | 2004-03-02 | Birdsong Medical Devices, Inc. | Canister inhaler having a spacer and easy to operate lever mechanism and a flexible, elastic mouthpiece |
| US6523536B2 (en) | 2001-03-12 | 2003-02-25 | Birdsong Medical Devices, Inc. | Dual-canister inhaler having a spacer and easy to operate lever mechanism |
| US6681768B2 (en) | 2001-06-22 | 2004-01-27 | Sofotec Gmbh & Co. Kg | Powder formulation disintegrating system and method for dry powder inhalers |
| DE10129703A1 (de) * | 2001-06-22 | 2003-01-02 | Sofotec Gmbh & Co Kg | Zerstäubungssystem für eine Pulvermischung und Verfahren für Trockenpulverinhalatoren |
| US7258118B2 (en) | 2002-01-24 | 2007-08-21 | Sofotec Gmbh & Co, Kg | Pharmaceutical powder cartridge, and inhaler equipped with same |
| DE10202940A1 (de) * | 2002-01-24 | 2003-07-31 | Sofotec Gmbh & Co Kg | Patrone für einen Pulverinhalator |
| EP1494732B1 (en) | 2002-03-20 | 2008-01-30 | MannKind Corporation | Inhalation apparatus |
| US20030205226A1 (en) | 2002-05-02 | 2003-11-06 | Pre Holding, Inc. | Aerosol medication inhalation system |
| US6904908B2 (en) | 2002-05-21 | 2005-06-14 | Trudell Medical International | Visual indicator for an aerosol medication delivery apparatus and system |
| CA2694183C (en) * | 2002-10-11 | 2013-06-25 | Otsuka Techno Corporation | Powder inhalator |
| DE10300032B3 (de) * | 2003-01-03 | 2004-05-27 | E. Braun Gmbh | Pulverinhalator |
| GB2398254B (en) * | 2003-02-11 | 2005-12-07 | Bespak Plc | Dispensing Apparatus |
| US20060231096A1 (en) * | 2003-06-11 | 2006-10-19 | Hitachi, Ltd. | Inhalation type medication apparatus |
| GB0315509D0 (en) * | 2003-07-02 | 2003-08-06 | Meridica Ltd | Dispensing device |
| SE0303569L (sv) * | 2003-12-03 | 2005-06-04 | Microdrug Ag | DPI för avlämning av fuktkänsliga medikament |
| ES2257152B1 (es) | 2004-05-31 | 2007-07-01 | Laboratorios Almirall S.A. | Combinaciones que comprenden agentes antimuscarinicos y agonistas beta-adrenergicos. |
| NZ551669A (en) | 2004-05-31 | 2010-07-30 | Almirall Lab | Combinations comprising antimuscarinic agents and PDE4 inhibitors |
| RU2413544C2 (ru) | 2004-07-16 | 2011-03-10 | Алмиралл, С.А. | Ингалятор и картридж для лекарственного порошкового препарата и способ работы ингалятора |
| DK1786784T3 (da) | 2004-08-20 | 2011-02-14 | Mannkind Corp | Katalyse af diketopiperazinsyntese |
| CN104436170B (zh) | 2004-08-23 | 2018-02-23 | 曼金德公司 | 用于药物输送的二酮哌嗪盐 |
| DK2486942T3 (en) | 2004-11-24 | 2019-01-28 | Meda Pharmaceuticals Inc | COMPOSITIONS CONTAINING AZELASTINE AND PROCEDURES FOR USING IT |
| US20070020330A1 (en) * | 2004-11-24 | 2007-01-25 | Medpointe Healthcare Inc. | Compositions comprising azelastine and methods of use thereof |
| US8758816B2 (en) | 2004-11-24 | 2014-06-24 | Meda Pharmaceuticals Inc. | Compositions comprising azelastine and methods of use thereof |
| GB0507100D0 (en) | 2005-04-08 | 2005-05-11 | Team Holdings Uk Ltd | Improvements in or relating to inhalers |
| NZ563417A (en) | 2005-05-18 | 2012-01-12 | Mpex Pharmaceuticals Inc | Aerosolized fluoroquinolones and uses thereof |
| US8524735B2 (en) | 2005-05-18 | 2013-09-03 | Mpex Pharmaceuticals, Inc. | Aerosolized fluoroquinolones and uses thereof |
| ES2265276B1 (es) | 2005-05-20 | 2008-02-01 | Laboratorios Almirall S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor beta2 adrenergico. |
| AU2006290227B2 (en) | 2005-09-14 | 2012-08-02 | Mannkind Corporation | Method of drug formulation based on increasing the affinity of crystalline microparticle surfaces for active agents |
| KR20080096809A (ko) | 2006-02-22 | 2008-11-03 | 맨카인드 코포레이션 | 디케토피페라진 및 활성제를 포함하는 마이크로입자의 약학특성의 개선 방법 |
| JP5188991B2 (ja) * | 2006-03-03 | 2013-04-24 | エスティーシー．ユーエヌエム | 空力弾性分配メカニズムを有するドライパウダー吸入器 |
| ES2319596B1 (es) | 2006-12-22 | 2010-02-08 | Laboratorios Almirall S.A. | Nuevos derivados de los acidos amino-nicotinico y amino-isonicotinico. |
| ES2378786T3 (es) * | 2006-12-22 | 2012-04-17 | Almirall, S.A. | Dispositivo de inhalación para fármacos en forma de polvo |
| ES2306595B1 (es) | 2007-02-09 | 2009-09-11 | Laboratorios Almirall S.A. | Sal de napadisilato de 5-(2-((6-(2,2-difluoro-2-feniletoxi)hexil)amino)-1-hidroxietil)-8-hidroxiquinolin-2(1h)-ona como agonista del receptor adrenergico beta2. |
| ES2320955B1 (es) | 2007-03-02 | 2010-03-16 | Laboratorios Almirall S.A. | Nuevos derivados de 3-((1,2,4)triazolo(4,3-a)piridin-7-il)benzamida. |
| CA2693771A1 (en) * | 2007-07-13 | 2009-01-22 | Abbott Biotechnology Ltd. | Methods and compositions for pulmonary administration of a tnf.alpha. inhibitor |
| UY31272A1 (es) | 2007-08-10 | 2009-01-30 | Almirall Lab | Nuevos derivados de ácido azabifenilaminobenzoico |
| DE102007056263A1 (de) * | 2007-11-22 | 2009-05-28 | Siegfried Generics International Ag | Dosiervorrichtung zur Inhalierung einer pulverförmigen Substanz |
| ES2320961B1 (es) | 2007-11-28 | 2010-03-17 | Laboratorios Almirall, S.A. | Derivados de 4-(2-amino-1-hidroxietil)fenol como agonistas del receptor adrenergico beta2. |
| ES2394589T3 (es) | 2007-12-14 | 2013-02-04 | Aerodesigns, Inc | Suministro de productos alimenticios transformables en aerosol |
| EP2096105A1 (en) | 2008-02-28 | 2009-09-02 | Laboratorios Almirall, S.A. | Derivatives of 4-(2-amino-1-hydroxyethyl)phenol as agonists of the b2 adrenergic receptor |
| EP2100599A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2100598A1 (en) | 2008-03-13 | 2009-09-16 | Laboratorios Almirall, S.A. | Inhalation composition containing aclidinium for treatment of asthma and chronic obstructive pulmonary disease |
| EP2108641A1 (en) | 2008-04-11 | 2009-10-14 | Laboratorios Almirall, S.A. | New substituted spiro[cycloalkyl-1,3'-indo]-2'(1'H)-one derivatives and their use as p38 mitogen-activated kinase inhibitors |
| EP2113503A1 (en) | 2008-04-28 | 2009-11-04 | Laboratorios Almirall, S.A. | New substituted indolin-2-one derivatives and their use as p39 mitogen-activated kinase inhibitors |
| SG10201507036TA (en) | 2008-06-13 | 2015-10-29 | Mannkind Corp | A dry powder inhaler and system for drug delivery |
| US8485180B2 (en) | 2008-06-13 | 2013-07-16 | Mannkind Corporation | Dry powder drug delivery system |
| US20190262557A1 (en) * | 2010-03-04 | 2019-08-29 | Mannkind Corporation | Dry powder drug delivery system |
| EP2135610A1 (en) | 2008-06-20 | 2009-12-23 | Laboratorios Almirall, S.A. | Combination comprising DHODH inhibitors and methotrexate |
| EP2609954B1 (en) | 2008-06-20 | 2021-12-29 | MannKind Corporation | An interactive apparatus for real-time profiling of inhalation efforts |
| TWI614024B (zh) | 2008-08-11 | 2018-02-11 | 曼凱公司 | 超快起作用胰島素之用途 |
| CA2739897C (en) | 2008-10-07 | 2017-10-03 | Mpex Pharmaceuticals, Inc. | Aerosol fluoroquinolone formulations for improved pharmacokinetics |
| US8629139B2 (en) | 2008-10-07 | 2014-01-14 | Mpex Pharmaceuticals, Inc. | Topical use of Levofloxacin for reducing lung inflammation |
| EP2177521A1 (en) | 2008-10-14 | 2010-04-21 | Almirall, S.A. | New 2-Amidothiadiazole Derivatives |
| EP2196465A1 (en) | 2008-12-15 | 2010-06-16 | Almirall, S.A. | (3-oxo)pyridazin-4-ylurea derivatives as PDE4 inhibitors |
| UY32297A (es) | 2008-12-22 | 2010-05-31 | Almirall Sa | Sal mesilato de 5-(2-{[6-(2,2-difluoro-2-fenilitoxi) hexil]amino}-1-hidroxietil)-8-hidroxiquinolin-2( 1h)-ona como agonista del receptor b(beta)2 acrenérgico |
| EP2202232A1 (en) | 2008-12-26 | 2010-06-30 | Laboratorios Almirall, S.A. | 1,2,4-oxadiazole derivatives and their therapeutic use |
| US8314106B2 (en) | 2008-12-29 | 2012-11-20 | Mannkind Corporation | Substituted diketopiperazine analogs for use as drug delivery agents |
| DE202008017185U1 (de) | 2008-12-30 | 2010-05-12 | Siegfried Generics International Ag | Dosiervorrichtung |
| EP2210890A1 (en) | 2009-01-19 | 2010-07-28 | Almirall, S.A. | Oxadiazole derivatives as S1P1 receptor agonists |
| EP2210615A1 (en) | 2009-01-21 | 2010-07-28 | Almirall, S.A. | Combinations comprising methotrexate and DHODH inhibitors |
| EP2221055A1 (en) | 2009-02-18 | 2010-08-25 | Almirall, S.A. | 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one for the treatment of lung function |
| EP2221297A1 (en) | 2009-02-18 | 2010-08-25 | Almirall, S.A. | 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one and its use in the treatment of pulmonary diseases |
| EP2226323A1 (en) | 2009-02-27 | 2010-09-08 | Almirall, S.A. | New tetrahydropyrazolo[3,4-c]isoquinolin-5-amine derivatives |
| MX2011009512A (es) | 2009-03-11 | 2011-11-29 | Mannkind Corp | Aparato, sistema y metodo para medir la resistencia de un inhalador. |
| EP2228368A1 (en) | 2009-03-12 | 2010-09-15 | Almirall, S.A. | Process for manufacturing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-hydroxyethyl)-8-hydroxyquinolin-2(1H)-one |
| EP2239256A1 (en) | 2009-03-13 | 2010-10-13 | Almirall, S.A. | Sodium salt of 5-cyclopropyl-2-{[2-(2,6-difluorophenyl)pyrimidin-5-yl]amino}benzoic acid as DHODH inhibitor |
| MY157166A (en) | 2009-06-12 | 2016-05-13 | Mankind Corp | Diketopiperazine microparticles with defined specific surface areas |
| DK2473170T3 (da) | 2009-09-04 | 2019-08-12 | Horizon Orphan Llc | Anvendelse af aerosoliseret levofloxacin til behandling af cystisk fibrose |
| EP2305660A1 (en) | 2009-09-25 | 2011-04-06 | Almirall, S.A. | New thiadiazole derivatives |
| EP2314577A1 (en) | 2009-10-16 | 2011-04-27 | Almirall, S.A. | Process for manufacturing 2-[(3,5-difluoro-3'-methoxy-1,1'-biphenyl-4-yl)amino]nicotinic acid |
| CA2778698A1 (en) | 2009-11-03 | 2011-05-12 | Mannkind Corporation | An apparatus and method for simulating inhalation efforts |
| EP2322176A1 (en) | 2009-11-11 | 2011-05-18 | Almirall, S.A. | New 7-phenyl-[1,2,4]triazolo[4,3-a]pyridin-3(2H)-one derivatives |
| CA2779488A1 (en) | 2009-11-12 | 2011-05-19 | Stc.Unm | Dry powder inhaler with flutter dispersion member |
| EP2343287A1 (en) | 2009-12-10 | 2011-07-13 | Almirall, S.A. | New 2-aminothiadiazole derivatives |
| EP2338888A1 (en) | 2009-12-24 | 2011-06-29 | Almirall, S.A. | Imidazopyridine derivatives as JAK inhibitors |
| EP2360158A1 (en) | 2010-02-18 | 2011-08-24 | Almirall, S.A. | Pyrazole derivatives as jak inhibitors |
| UY33213A (es) | 2010-02-18 | 2011-09-30 | Almirall Sa | Derivados de pirazol como inhibidores de jak |
| EP2366702A1 (en) | 2010-03-18 | 2011-09-21 | Almirall, S.A. | New oxadiazole derivatives |
| EP2380890A1 (en) | 2010-04-23 | 2011-10-26 | Almirall, S.A. | New 7,8-dihydro-1,6-naphthyridin-5(6h)-one-derivatives as PDE4 inhibitors |
| EP2386555A1 (en) | 2010-05-13 | 2011-11-16 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and m3 muscarinic antagonist activities |
| EP2390252A1 (en) | 2010-05-19 | 2011-11-30 | Almirall, S.A. | New pyrazole derivatives |
| EP2394998A1 (en) | 2010-05-31 | 2011-12-14 | Almirall, S.A. | 3-(5-Amino-6-oxo-1,6-dihydropyridazin-3-yl)-biphenyl derivatives as PDE4 inhibitors |
| EP2397482A1 (en) | 2010-06-15 | 2011-12-21 | Almirall, S.A. | Heteroaryl imidazolone derivatives as jak inhibitors |
| IL223742A (en) | 2010-06-21 | 2016-06-30 | Mannkind Corp | A dry powder inhaler and preparation for it |
| EP2441755A1 (en) | 2010-09-30 | 2012-04-18 | Almirall, S.A. | Pyridine- and isoquinoline-derivatives as Syk and JAK kinase inhibitors |
| EP2455081A1 (en) | 2010-11-23 | 2012-05-23 | Almirall, S.A. | S1P1 receptor agonists for use in the treatment of crohn's disease |
| EP2455080A1 (en) | 2010-11-23 | 2012-05-23 | Almirall, S.A. | S1P1 receptor agonists for use in the treatment of multiple sclerosis |
| EP2457900A1 (en) | 2010-11-25 | 2012-05-30 | Almirall, S.A. | New pyrazole derivatives having CRTh2 antagonistic behaviour |
| EP2463289A1 (en) | 2010-11-26 | 2012-06-13 | Almirall, S.A. | Imidazo[1,2-b]pyridazine derivatives as JAK inhibitors |
| JP6050758B2 (ja) | 2010-12-07 | 2016-12-21 | レスピラ セラピューティクス インコーポレイテッドＲｅｓｐｉｒａ Ｔｈｅｒａｐｅｕｔｉｃｓ，Ｉｎｃ． | 乾燥粉末吸入器及びその作動方法 |
| ES2913095T3 (es) | 2011-01-31 | 2022-05-31 | Avalyn Pharma Inc | Compuestos de pirfenidona y análogos de piridona en aerosol y usos de los mismos |
| EP2489663A1 (en) | 2011-02-16 | 2012-08-22 | Almirall, S.A. | Compounds as syk kinase inhibitors |
| EP2694402B1 (en) | 2011-04-01 | 2017-03-22 | MannKind Corporation | Blister package for pharmaceutical cartridges |
| EP2510928A1 (en) | 2011-04-15 | 2012-10-17 | Almirall, S.A. | Aclidinium for use in improving the quality of sleep in respiratory patients |
| EP2518071A1 (en) | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Imidazopyridine derivatives as PI3K inhibitors |
| EP2518070A1 (en) | 2011-04-29 | 2012-10-31 | Almirall, S.A. | Pyrrolotriazinone derivatives as PI3K inhibitors |
| EP2527344A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | Pyridin-2(1H)-one derivatives useful as medicaments for the treatment of myeloproliferative disorders, transplant rejection, immune-mediated and inflammatory diseases |
| EP2526945A1 (en) | 2011-05-25 | 2012-11-28 | Almirall, S.A. | New CRTH2 Antagonists |
| WO2012174472A1 (en) | 2011-06-17 | 2012-12-20 | Mannkind Corporation | High capacity diketopiperazine microparticles |
| EP2548863A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists. |
| EP2548876A1 (en) | 2011-07-18 | 2013-01-23 | Almirall, S.A. | New CRTh2 antagonists |
| EP2554544A1 (en) | 2011-08-01 | 2013-02-06 | Almirall, S.A. | Pyridin-2(1h)-one derivatives as jak inhibitors |
| WO2013045996A1 (en) | 2011-09-26 | 2013-04-04 | Trudell Medical International | Dose counter and medication delivery device |
| EP2578570A1 (en) | 2011-10-07 | 2013-04-10 | Almirall, S.A. | Novel process for preparing 5-(2-{[6-(2,2-difluoro-2-phenylethoxy)hexyl]amino}-1(r)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one via novel intermediates of synthesis. |
| HK1200318A1 (en) | 2011-10-24 | 2015-08-07 | 曼金德公司 | Methods and compositions for treating pain |
| GB201118845D0 (en) * | 2011-11-01 | 2011-12-14 | Euro Celtique Sa | Dispenser |
| EP2592077A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| EP2592078A1 (en) | 2011-11-11 | 2013-05-15 | Almirall, S.A. | New cyclohexylamine derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activities |
| EP2617448A1 (en) * | 2012-01-20 | 2013-07-24 | Almirall S.A. | Inhalation device for powdered drugs |
| EP2617449A1 (en) | 2012-01-20 | 2013-07-24 | Almirall S.A. | Inhalation device for powdered drugs |
| EP2617450A1 (en) | 2012-01-20 | 2013-07-24 | Almirall S.A. | Inhaltion device for powdered drugs |
| US9603906B2 (en) | 2012-02-01 | 2017-03-28 | Protalix Ltd. | Inhalable liquid formulations of DNase I |
| US10463815B2 (en) | 2012-02-21 | 2019-11-05 | Respira Therapeutics, Inc. | Inhaler to deliver substances for prophylaxis or prevention of disease or injury caused by the inhalation of biological or chemical agents |
| EP3421042B1 (en) | 2012-03-07 | 2024-04-17 | Beyond Air Ltd | Inhalation of nitric oxide for treating respiratory diseases |
| EP2641900A1 (en) | 2012-03-20 | 2013-09-25 | Almirall, S.A. | Novel polymorphic Crystal forms of 5-(2-{[6-(2,2-difluoro-2-phenylethoxy) hexyl]amino}-1-(R)-hydroxyethyl)-8-hydroxyquinolin-2(1h)-one, heminapadisylate as agonist of the ß2 adrenergic receptor. |
| EP2647627A1 (en) | 2012-04-02 | 2013-10-09 | Almirall, S.A. | Salts of 5-[(1r)-2-({2-[4-(2,2-difluoro-2-phenylethoxy)phenyl] ethyl}amino)-1-hydroxyethyl]-8-hydroxyquinolin-2(1h)-one. |
| EP2666465A1 (en) | 2012-05-25 | 2013-11-27 | Almirall, S.A. | Novel dosage and formulation |
| EP2668941A1 (en) | 2012-05-31 | 2013-12-04 | Almirall, S.A. | Novel dosage form and formulation of abediterol |
| EP2872205B1 (en) | 2012-07-12 | 2017-02-08 | MannKind Corporation | Dry powder drug delivery systems |
| WO2014060431A1 (en) | 2012-10-16 | 2014-04-24 | Almirall, S.A. | Pyrrolotriazinone derivatives as pi3k inhibitors |
| US10159644B2 (en) | 2012-10-26 | 2018-12-25 | Mannkind Corporation | Inhalable vaccine compositions and methods |
| EP2738172A1 (en) | 2012-11-28 | 2014-06-04 | Almirall, S.A. | New bicyclic compounds as crac channel modulators |
| AU2013363837A1 (en) | 2012-12-17 | 2015-06-11 | Almirall, S.A. | New use of aclidinium |
| AU2013360866A1 (en) | 2012-12-18 | 2015-07-02 | Almirall, S.A. | New cyclohexyl and quinuclidinyl carbamate derivatives having beta2 adrenergic agonist and M3 muscarinic antagonist activity |
| UY35332A (es) | 2013-02-15 | 2014-11-28 | Almirall Sa | Derivados de pirrolotriazina como inhibidores de pi3k |
| WO2014144895A1 (en) | 2013-03-15 | 2014-09-18 | Mannkind Corporation | Microcrystalline diketopiperazine compositions and methods |
| EP2848615A1 (en) | 2013-07-03 | 2015-03-18 | Almirall, S.A. | New pyrazole derivatives as CRAC channel modulators |
| KR102465025B1 (ko) | 2013-07-18 | 2022-11-09 | 맨카인드 코포레이션 | 열-안정성 건조 분말 약제학적 조성물 및 방법 |
| JP6799201B2 (ja) | 2013-07-31 | 2020-12-16 | アヴァリン ファーマ インク． | エアロゾルチロシンキナーゼ阻害剤の化合物、及びその使用 |
| EP3030294B1 (en) | 2013-08-05 | 2020-10-07 | MannKind Corporation | Insufflation apparatus |
| WO2015091287A1 (en) | 2013-12-19 | 2015-06-25 | Almirall S.A. | Dosage formulation comprising salmeterol and fluticasone propionate |
| EP4491180A1 (en) | 2014-01-10 | 2025-01-15 | Avalyn Pharma Inc. | Aerosol pirfenidone and pyridone analog compounds and uses thereof |
| US10307464B2 (en) | 2014-03-28 | 2019-06-04 | Mannkind Corporation | Use of ultrarapid acting insulin |
| PE20170080A1 (es) | 2014-06-06 | 2017-03-16 | Univ Groningen | Inhalador de polvo seco activado por la respiracion |
| US10561806B2 (en) | 2014-10-02 | 2020-02-18 | Mannkind Corporation | Mouthpiece cover for an inhaler |
| WO2016057693A1 (en) | 2014-10-10 | 2016-04-14 | Alnylam Pharmaceuticals, Inc. | Methods and compositions for inhalation delivery of conjugated oligonucleotide |
| CN107427650A (zh) | 2015-01-14 | 2017-12-01 | 瑞必治公司 | 粉末分散方法和装置 |
| EP3061501A1 (en) | 2015-02-27 | 2016-08-31 | Rottapharm Ltd. | Composition for the treatment of acne |
| MA41938A (fr) | 2015-04-21 | 2018-02-28 | Almirall Sa | Dérivés hétérocycliques amino-substitués utilisés comme inhibiteurs des canaux sodiques |
| WO2016202800A1 (en) | 2015-06-16 | 2016-12-22 | Almirall, S.A. | Pyrrolotriazinone derivatives as pi3k inhibitors |
| EP3117825A1 (en) | 2015-07-16 | 2017-01-18 | Rottapharm S.p.A. | Oral formulation comprising berberine and morus alba extract |
| WO2017076990A1 (en) | 2015-11-05 | 2017-05-11 | Almirall, S.A. | Addition salts of n-[4-(4-{[(1s)-1-(5-methyl-4-oxo-3-phenyl-3,4-dihydropyrrolo[2,1-f][1,2,4]triazin-2-yl)ethyl]amino}-7h-pyrrolo[2,3-d]pyrimidin-5-yl)-1h-indol-6-yl]sulfamide |
| GB201605102D0 (en) | 2016-03-24 | 2016-05-11 | Nicoventures Holdings Ltd | Mechanical connector for electronic vapour provision system |
| WO2017192782A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Systems and methods comprising a droplet delivery device and a breathing assist device for therapeutic treatment |
| KR102122887B1 (ko) | 2016-05-03 | 2020-06-16 | 뉴마 레스퍼러토리 인코포레이티드 | 유체들의 폐기관계로의 전달을 위한 액적 전달 디바이스 및 사용 방법 |
| WO2017192774A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for the systemic delivery of therapeutic agents to the pulmonary system using a droplet delivery device |
| EP4624054A3 (en) | 2016-05-03 | 2025-11-19 | Pneuma Respiratory, Inc. | Methods for generating and delivering droplets to the pulmonary system using a droplet delivery device |
| WO2017192773A1 (en) | 2016-05-03 | 2017-11-09 | Pneuma Respiratory, Inc. | Methods for treatment of pulmonary lung diseases with improved therapeutic efficacy and improved dose efficiency |
| EP4223335A3 (en) | 2017-05-19 | 2023-11-08 | Pneuma Respiratory, Inc. | Dry powder delivery device and methods of use |
| TW201919682A (zh) | 2017-08-08 | 2019-06-01 | 西班牙商阿爾米雷爾有限公司 | 活化Ｎｒｆ２路徑的新穎化合物 |
| CN118203735A (zh) | 2017-10-04 | 2024-06-18 | 精呼吸股份有限公司 | 电子呼吸致动式直线型液滴输送装置及其使用方法 |
| EP3697481B1 (en) | 2017-10-17 | 2024-05-22 | Pneuma Respiratory, Inc. | Nasal drug delivery apparatus and methods of use |
| FR3072294B1 (fr) * | 2017-10-18 | 2019-10-11 | Aptar France Sas | Dispositif de distribution de produit fluide synchronise avec l'inhalation. |
| CA3082192A1 (en) | 2017-11-08 | 2019-05-16 | Pneuma Respiratory, Inc. | Electronic breath actuated in-line droplet delivery device with small volume ampoule and methods of use |
| CN110201278B (zh) * | 2018-02-28 | 2021-07-30 | 张江 | 用于吸入给药的药盒和吸入给药组合结构 |
| EP3773840B1 (en) * | 2018-04-02 | 2024-11-06 | Pneuma Respiratory, Inc. | Handheld digital nebulizer device and methods of use |
| RU189757U1 (ru) * | 2019-01-09 | 2019-06-03 | Федеральное государственное бюджетное учреждение "48 Центральный научно-исследовательский институт" Министерства обороны Российской Федерации | Дисковый распылитель для получения полидисперсных аэрозолей из порошкообразных материалов |
| WO2022240897A1 (en) | 2021-05-10 | 2022-11-17 | Sepelo Therapeutics, Llc | Pharmaceutical composition comprising delafloxacin for administration into the lung |
| WO2022271848A1 (en) | 2021-06-22 | 2022-12-29 | Pneuma Respiratory, Inc. | Droplet delivery device with push ejection |
| WO2023028364A1 (en) | 2021-08-27 | 2023-03-02 | Sepelo Therapeutics, Llc | Targeted compositions and uses therof |
| CN118414185A (zh) * | 2021-12-21 | 2024-07-30 | 凯西制药公司 | 粉末吸入器 |
| KR102795270B1 (ko) * | 2022-07-01 | 2025-04-15 | 주식회사 케이티앤지 | 인헤일러 |
| US20260033533A1 (en) | 2022-07-18 | 2026-02-05 | Pneuma Respiratory, Inc. | Small step size and high resolution aerosol generation system and method |
| CN117771490B (zh) * | 2023-12-20 | 2025-07-18 | 上海新黄河制药有限公司 | 一种双储库粉雾剂装置 |
Family Cites Families (37)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE483136A (enExample) * | 1947-09-04 | 1942-06-30 | ||
| US2587215A (en) * | 1949-04-27 | 1952-02-26 | Frank P Priestly | Inhalator |
| US3972123A (en) * | 1973-10-04 | 1976-08-03 | Black Robert B | Air-abrasive prophylaxis equipment |
| US4125969A (en) * | 1977-01-25 | 1978-11-21 | A. Long & Company Limited | Wet abrasion blasting |
| US4274403A (en) * | 1979-08-29 | 1981-06-23 | Struve Roger L | Inhaler |
| DE3043377A1 (de) * | 1980-11-17 | 1982-07-01 | Brugger, Inge, 8130 Starnberg | Zerstaeuber |
| EP0079478A1 (en) * | 1981-11-03 | 1983-05-25 | Miles Laboratories, Inc. | Medicament inhalation device |
| US4570630A (en) * | 1983-08-03 | 1986-02-18 | Miles Laboratories, Inc. | Medicament inhalation device |
| DE3335745C1 (de) * | 1983-10-01 | 1985-01-17 | Sanitätshaus Ulrich Klimt, 7910 Neu-Ulm | Inhalationsgerät |
| FI69963C (fi) * | 1984-10-04 | 1986-09-12 | Orion Yhtymae Oy | Doseringsanordning |
| DK481884D0 (da) * | 1984-10-09 | 1984-10-09 | Karl Holm | Medicinsk mund- eller svaelgsprayapparat |
| SE448277B (sv) * | 1985-04-12 | 1987-02-09 | Draco Ab | Indikeringsanordning vid en doseringsanordning for lekemedel |
| DE4004904A1 (de) * | 1990-02-16 | 1990-09-13 | Gerhard Brendel | Trommel-applikator |
| US5020527A (en) * | 1990-02-20 | 1991-06-04 | Texax-Glynn Corporation | Inhaler device with counter/timer means |
| GB9015522D0 (en) * | 1990-07-13 | 1990-08-29 | Braithwaite Philip W | Inhaler |
| DE4027391A1 (de) * | 1990-08-30 | 1992-03-12 | Boehringer Ingelheim Kg | Treibgasfreies inhalationsgeraet |
| DE69129188T2 (de) * | 1990-09-26 | 1998-07-30 | Pharmachemie B.V., Haarlem | Inhalator mit einem reservoir für mehrere dosierte inhalationsmittel, mit transportvorrichtung und mit wirbelkammer |
| GB9026025D0 (en) * | 1990-11-29 | 1991-01-16 | Boehringer Ingelheim Kg | Inhalation device |
| GB9107806D0 (en) * | 1991-04-12 | 1991-05-29 | Rochester N J Ltd | Gas extraction |
| BR9106690A (pt) * | 1991-04-15 | 1993-06-29 | Huhtamaeki Yhthymae Oy | Disposicao para medir uma dose de medicamentos pulverulento para inalacao e aparelho de inalacao dotado do mesmo |
| US5161524A (en) * | 1991-08-02 | 1992-11-10 | Glaxo Inc. | Dosage inhalator with air flow velocity regulating means |
| HUT64242A (en) * | 1991-08-15 | 1993-12-28 | Bon Del | Inhalator and method for inhaling |
| EP0826386B1 (en) * | 1991-08-26 | 2003-11-26 | Minnesota Mining And Manufacturing Company | Powder dispenser |
| US5341801A (en) * | 1991-12-03 | 1994-08-30 | Sandoz Ltd. | Inhaler |
| FR2684732B1 (fr) * | 1991-12-10 | 1994-02-18 | Somfy | Reducteur planetaire pour moteur tubulaire. |
| DE4211475A1 (de) * | 1991-12-14 | 1993-06-17 | Asta Medica Ag | Pulverinhalator |
| GB2262452B (en) * | 1991-12-19 | 1995-12-20 | Minnesota Mining & Mfg | Inhalation device |
| KR970004121B1 (ko) * | 1991-12-27 | 1997-03-25 | 마쯔시다덴기산교 가부시기가이샤 | 필름콘덴서와 그 제조방법 |
| GB9203761D0 (en) * | 1992-02-21 | 1992-04-08 | Innovata Biomed Ltd | Inhaler |
| US5284133A (en) * | 1992-07-23 | 1994-02-08 | Armstrong Pharmaceuticals, Inc. | Inhalation device with a dose-timer, an actuator mechanism, and patient compliance monitoring means |
| DE4239402A1 (de) * | 1992-11-24 | 1994-05-26 | Bayer Ag | Pulverinhalator |
| CA2152088C (en) * | 1992-12-18 | 1999-12-07 | Thomas J. Ambrosio | Inhaler for powdered medications |
| DE4319514C2 (de) * | 1993-06-14 | 2003-06-18 | Sofotec Gmbh & Co Kg | Pulverinhalator |
| DE4340768A1 (de) * | 1993-11-30 | 1995-06-01 | Bayer Ag | Vorrichtung zum Inhalieren |
| ZA942721B (en) * | 1994-04-20 | 1995-01-09 | Dieter Koehler | Process and apparatus for producing an aerosol from a pulverulent substance |
| FI942196A7 (fi) * | 1994-05-11 | 1995-11-12 | Orion Yhtymae Oy | Jauheinhalaattori |
| JP3299971B2 (ja) * | 1995-06-21 | 2002-07-08 | アスタ メディカ アクチエンゲゼルシャフト | 一体的に形成された調量装置を備えた薬用粉末カートリッジおよび粉末薬剤吸入器 |
-
1996
- 1996-06-03 JP JP50354297A patent/JP3299971B2/ja not_active Expired - Lifetime
- 1996-06-03 EP EP96920776A patent/EP0837710B1/en not_active Expired - Lifetime
- 1996-06-03 AU AU62211/96A patent/AU719449B2/en not_active Expired
- 1996-06-03 PL PL96343227A patent/PL182715B1/pl unknown
- 1996-06-03 BR BR9608997A patent/BR9608997A/pt not_active IP Right Cessation
- 1996-06-03 DK DK96920776T patent/DK0837710T3/da active
- 1996-06-03 ES ES96920776T patent/ES2168488T3/es not_active Expired - Lifetime
- 1996-06-03 PL PL96324504A patent/PL182198B1/pl unknown
- 1996-06-03 SK SK1725-97A patent/SK284303B6/sk not_active IP Right Cessation
- 1996-06-03 TR TR97/01665T patent/TR199701665T1/xx unknown
- 1996-06-03 SI SI9620081A patent/SI9620081B/sl unknown
- 1996-06-03 IL IL12249496A patent/IL122494A/en not_active IP Right Cessation
- 1996-06-03 PT PT96920776T patent/PT837710E/pt unknown
- 1996-06-03 AT AT96920776T patent/ATE209518T1/de active
- 1996-06-03 WO PCT/EP1996/002396 patent/WO1997000703A1/en not_active Ceased
- 1996-06-03 CA CA002378713A patent/CA2378713C/en not_active Expired - Lifetime
- 1996-06-03 HU HU9802201A patent/HU220227B/hu unknown
- 1996-06-03 CA CA002225396A patent/CA2225396C/en not_active Expired - Lifetime
- 1996-06-03 CN CNB96194885XA patent/CN1181896C/zh not_active Expired - Lifetime
- 1996-06-03 CN CNB2004100014871A patent/CN1325129C/zh not_active Expired - Lifetime
- 1996-06-03 CZ CZ19974139A patent/CZ294700B6/cs not_active IP Right Cessation
- 1996-06-03 RU RU98101190/14A patent/RU2162346C2/ru active
- 1996-06-03 CZ CZ19991894A patent/CZ294782B6/cs not_active IP Right Cessation
- 1996-06-03 NZ NZ502870A patent/NZ502870A/en not_active IP Right Cessation
- 1996-06-03 KR KR1019970709638A patent/KR100269060B1/ko not_active Expired - Lifetime
- 1996-06-03 DE DE69617431T patent/DE69617431T2/de not_active Expired - Lifetime
- 1996-06-03 NZ NZ310990A patent/NZ310990A/xx not_active IP Right Cessation
- 1996-06-17 IN IN1120CA1996 patent/IN189233B/en unknown
- 1996-06-18 TW TW085107360A patent/TW325409B/zh not_active IP Right Cessation
- 1996-06-20 ID IDP961768A patent/ID17207A/id unknown
- 1996-06-20 AR ARP960103232A patent/AR002534A1/es unknown
- 1996-06-20 HR HR960294A patent/HRP960294B1/xx not_active IP Right Cessation
- 1996-06-21 US US08/667,414 patent/US5840279A/en not_active Expired - Lifetime
-
1997
- 1997-12-17 NO NO19975945A patent/NO314879B1/no not_active IP Right Cessation
-
1998
- 1998-07-10 US US09/113,652 patent/US6071498A/en not_active Expired - Lifetime
Also Published As
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| EP0865302B1 (de) | Inhalator zur mehrfachen dosisweisen abgabe eines pharmakologischen trockenpulvers | |
| DE69102928T2 (de) | Einrichtung zur Verabreichung pulverisierter medizinischer Substanzen. | |
| DE102014005646B4 (de) | Pulverinhalator und Pulverinhalationsset | |
| EP0547429B1 (de) | Pulverinhalator | |
| DE69515536T2 (de) | Vorrichtung zum Inhalieren von Pulverarzneimitteln | |
| DE69521472T2 (de) | Inhaliervorrichtung für pulverförmige Substanzen | |
| DE69101600T2 (de) | Inhalationsvorrichtung zur mehrfachen Ausgabe von Einzeldosen pulverförmiger Arzneimittel. | |
| DE60017886T2 (de) | Pulverinhalator für ein kombiniertes medikament | |
| DE102014005647B4 (de) | Pulverinhalator und Pulverinhalatorset | |
| DE69103281T2 (de) | Inhaliergerät. | |
| DE69108929T2 (de) | Aerosol-abgabevorrichtung mit anzeigeanordnung. | |
| DE69004749T2 (de) | Einrichtung zur Inhalation eines Medikaments. | |
| DE69416245T2 (de) | Vorrichtung und verfahren zur dosierten abgabe von pulverförmigen arzneistoffen | |
| AT396872B (de) | Gerät zur verabreichung von medikamenten in pulverform | |
| DE69215994T2 (de) | Inhalator | |
| DE69607015T2 (de) | Inhalationsvorrichtung zur genauen und reproduzierbaren, datierten abgabe von pulverförmigen arzneistoffen | |
| DE60211507T2 (de) | Pulverinhalator | |
| DE69333554T2 (de) | Pulverinhalator | |
| DE69133101T2 (de) | Pulverinhalator | |
| EP1590027B1 (de) | Vorrichtung zum einnehmen von pulverförmigen, körnigen oder granulatförmigen Substanzen | |
| DE60020575T2 (de) | Abgabevorrichtung für Medizin | |
| DE69226444T2 (de) | Inhalationsgerat | |
| CH629102A5 (de) | Inhalationsgeraet. | |
| KR19990028323A (ko) | 일체된 미터링 장치를 가진 약제 분말 카트리지 및 분말 약 흡입기 | |
| DE19522415C2 (de) | Arzneimittelpulverpatrone mit integrierter Dosiereinrichtung und Pulverinhalator mit Mitteln zum Betätigen der Dosiereinrichtung der Arzneimittelpulverpatrone |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SOFOTEC GMBH & CO. KG, 60314 FRANKFURT, DE |
|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: SOFOTEC GMBH & CO. KG, 61352 BAD HOMBURG, DE |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: MEDA PHARMA GMBH & CO. KG, 61352 BAD HOMBURG, DE |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: LABORATORIOS ALLMIRALL,S.A., BARCELONA, ES |
|
| 8328 | Change in the person/name/address of the agent |
Representative=s name: FLEISCHER, GODEMEYER, KIERDORF & PARTNER, PATENTAN |
|
| 8327 | Change in the person/name/address of the patent owner |
Owner name: ALMIRALL S.A., BARCELONA, ES |
|
| R082 | Change of representative |
Ref document number: 837710 Country of ref document: EP Representative=s name: FLEISCHER, GODEMEYER, KIERDORF & PARTNER, PATE, DE |