DE60219319D1 - Trockene hämostatische zusammensetzungen und verfahren zu ihrer herstellung - Google Patents
Trockene hämostatische zusammensetzungen und verfahren zu ihrer herstellungInfo
- Publication number
- DE60219319D1 DE60219319D1 DE60219319T DE60219319T DE60219319D1 DE 60219319 D1 DE60219319 D1 DE 60219319D1 DE 60219319 T DE60219319 T DE 60219319T DE 60219319 T DE60219319 T DE 60219319T DE 60219319 D1 DE60219319 D1 DE 60219319D1
- Authority
- DE
- Germany
- Prior art keywords
- cross
- linked gelatin
- powder
- linked
- production
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
- A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- A61K38/43—Enzymes; Proenzymes; Derivatives thereof
- A61K38/46—Hydrolases (3)
- A61K38/48—Hydrolases (3) acting on peptide bonds (3.4)
- A61K38/482—Serine endopeptidases (3.4.21)
- A61K38/4833—Thrombin (3.4.21.5)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/001—Use of materials characterised by their function or physical properties
- A61L24/0031—Hydrogels or hydrocolloids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L24/00—Surgical adhesives or cements; Adhesives for colostomy devices
- A61L24/04—Surgical adhesives or cements; Adhesives for colostomy devices containing macromolecular materials
- A61L24/10—Polypeptides; Proteins
- A61L24/104—Gelatin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/04—Antihaemorrhagics; Procoagulants; Haemostatic agents; Antifibrinolytic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2400/00—Materials characterised by their function or physical properties
- A61L2400/04—Materials for stopping bleeding
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Public Health (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Surgery (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Gastroenterology & Hepatology (AREA)
- Immunology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Materials Engineering (AREA)
- Dispersion Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Materials For Medical Uses (AREA)
- Medicinal Preparation (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Processes Of Treating Macromolecular Substances (AREA)
- Compositions Of Macromolecular Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US908464 | 2001-07-17 | ||
US09/908,464 US7435425B2 (en) | 2001-07-17 | 2001-07-17 | Dry hemostatic compositions and methods for their preparation |
PCT/US2002/020022 WO2003007845A1 (en) | 2001-07-17 | 2002-06-21 | Dry hemostatic compositions and methods for their preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE60219319D1 true DE60219319D1 (de) | 2007-05-16 |
DE60219319T2 DE60219319T2 (de) | 2008-01-03 |
Family
ID=25425842
Family Applications (2)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60230079T Expired - Lifetime DE60230079D1 (de) | 2001-07-17 | 2002-06-21 | Trockene hämostatische Zusammensetzungen und Verfahren zu ihrer Herstellung |
DE60219319T Expired - Lifetime DE60219319T2 (de) | 2001-07-17 | 2002-06-21 | Trockene hämostatische zusammensetzungen und verfahren zu ihrer herstellung |
Family Applications Before (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE60230079T Expired - Lifetime DE60230079D1 (de) | 2001-07-17 | 2002-06-21 | Trockene hämostatische Zusammensetzungen und Verfahren zu ihrer Herstellung |
Country Status (16)
Country | Link |
---|---|
US (4) | US7435425B2 (de) |
EP (2) | EP1414370B1 (de) |
JP (1) | JP4316374B2 (de) |
KR (1) | KR100904582B1 (de) |
CN (2) | CN101284146B (de) |
AT (2) | ATE358455T1 (de) |
AU (1) | AU2002345846B2 (de) |
BR (1) | BRPI0211258B8 (de) |
CA (1) | CA2453592C (de) |
DE (2) | DE60230079D1 (de) |
DK (2) | DK1414370T3 (de) |
ES (2) | ES2284883T3 (de) |
HK (2) | HK1060277A1 (de) |
MX (1) | MXPA04000514A (de) |
PT (2) | PT1414370E (de) |
WO (1) | WO2003007845A1 (de) |
Families Citing this family (77)
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US7871637B2 (en) | 1996-08-27 | 2011-01-18 | Baxter International Inc. | Dry hemostatic compositions and methods for their preparation |
US8303981B2 (en) | 1996-08-27 | 2012-11-06 | Baxter International Inc. | Fragmented polymeric compositions and methods for their use |
US8603511B2 (en) | 1996-08-27 | 2013-12-10 | Baxter International, Inc. | Fragmented polymeric compositions and methods for their use |
US7923431B2 (en) * | 2001-12-21 | 2011-04-12 | Ferrosan Medical Devices A/S | Haemostatic kit, a method of preparing a haemostatic agent and a method of promoting haemostatis |
CA2509914A1 (en) | 2002-12-11 | 2004-06-24 | Ferrosan A/S | Gelatine-based materials as swabs |
US8834864B2 (en) | 2003-06-05 | 2014-09-16 | Baxter International Inc. | Methods for repairing and regenerating human dura mater |
US7927626B2 (en) * | 2003-08-07 | 2011-04-19 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
US20060019868A1 (en) * | 2004-01-30 | 2006-01-26 | Pendharkar Sanyog M | Hemostatic compositions and devices |
US8440225B2 (en) * | 2003-08-07 | 2013-05-14 | Ethicon, Inc. | Process of making flowable hemostatic compositions and devices containing such compositions |
WO2005072700A2 (en) * | 2004-01-30 | 2005-08-11 | Ferrosan A/S | Haemostatic sprays and compositions |
US7109163B2 (en) * | 2004-01-30 | 2006-09-19 | Ethicon, Inc. | Hemostatic compositions and devices |
US8119160B2 (en) * | 2004-06-29 | 2012-02-21 | Ethicon, Inc. | Hemostatic compositions and devices |
CN101001649B (zh) | 2004-07-09 | 2011-08-31 | 弗罗桑医疗设备公司 | 包括透明质酸的止血组合物及其制备方法 |
FR2881651A1 (fr) * | 2005-02-09 | 2006-08-11 | Urodelia Sa | Nouveau produit pharmaceutique et procede de fabrication de ce produit pharmaceutique |
EP2093256A3 (de) * | 2005-07-28 | 2009-10-14 | Carnegie Mellon University | Biokompatible Polymere und Verwendungsverfahren |
JP5558002B2 (ja) * | 2005-12-16 | 2014-07-23 | オクセラ インコーポレイテッド | シュウ酸塩低減化のための組成物および方法 |
CA2651941C (en) | 2006-05-31 | 2015-02-17 | Baxter International Inc. | Method for directed cell in-growth and controlled tissue regeneration in spinal surgery |
TWI436793B (zh) | 2006-08-02 | 2014-05-11 | Baxter Int | 快速作用之乾密封膠及其使用和製造方法 |
AU2007334394B2 (en) | 2006-12-15 | 2013-06-06 | Lifebond Ltd. | Gelatin-transglutaminase hemostatic dressings and sealants |
US8133484B2 (en) | 2006-12-15 | 2012-03-13 | Lifebond Ltd | Hemostatic materials and dressing |
US20100143447A1 (en) * | 2006-12-19 | 2010-06-10 | Ferrosan A/S | Wound or tissue dressing comprising lactic acid bacteria |
DE102007038125A1 (de) | 2007-08-03 | 2009-02-05 | Aesculap Ag | Kombination zum Verkleben von biologischen Geweben |
MX2010004838A (es) | 2007-10-30 | 2010-05-21 | Baxter Int | Uso de una biomatriz de colageno biofuncional regenerativa para tratar defectos viscerales o parietales. |
EP3338549A1 (de) * | 2007-11-20 | 2018-06-27 | Pioneer Surgical Orthobiologics, Inc. | Kryokonservierung von zellen mittels kreuzvernetzter bioaktiver hydrogel-matrixpartikel |
CA2716872C (en) | 2008-02-29 | 2015-02-10 | Ferrosan Medical Devices A/S | Device for promotion of hemostasis and/or wound healing |
US9629798B2 (en) | 2008-04-03 | 2017-04-25 | Mallinckrodt Pharma Ip Trading D.A.C. | Hemostatic microspheres |
CN102124058B (zh) | 2008-06-18 | 2014-05-28 | 生命连结有限公司 | 改进的交联组合物 |
US8110208B1 (en) | 2009-03-30 | 2012-02-07 | Biolife, L.L.C. | Hemostatic compositions for arresting blood flow from an open wound or surgical site |
US9039783B2 (en) | 2009-05-18 | 2015-05-26 | Baxter International, Inc. | Method for the improvement of mesh implant biocompatibility |
JP5719355B2 (ja) | 2009-06-16 | 2015-05-20 | バクスター・インターナショナル・インコーポレイテッドBaxter International Incorp0Rated | 止血スポンジ |
US20110081398A1 (en) * | 2009-10-01 | 2011-04-07 | Tyco Healthcare Group Lp | Multi-mechanism surgical compositions |
US8968785B2 (en) * | 2009-10-02 | 2015-03-03 | Covidien Lp | Surgical compositions |
US20110081701A1 (en) * | 2009-10-02 | 2011-04-07 | Timothy Sargeant | Surgical compositions |
KR101811070B1 (ko) | 2009-12-16 | 2017-12-20 | 백스터 인터내셔널 인코포레이티드 | 지혈 스폰지 |
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EP2575775B1 (de) | 2010-06-01 | 2018-04-04 | Baxter International Inc. | Verfahren zur herstellung von trockenen und stabilen hämostatischen zusammensetzungen |
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CA2801120C (en) | 2010-06-01 | 2019-08-20 | Baxter International Inc. | Process for making dry and stable hemostatic compositions |
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ES2938541T3 (es) | 2011-10-11 | 2023-04-12 | Baxter Int | Composición hemostática |
KR102102002B1 (ko) | 2011-10-11 | 2020-04-20 | 백스터 인터내셔널 인코포레이티드 | 지혈 조성물 |
ES2938566T3 (es) | 2011-10-11 | 2023-04-12 | Baxter Int | Composiciones hemostaticas |
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RU2700162C2 (ru) | 2013-06-21 | 2019-09-13 | Ферросан Медикал Дивайсиз А/С | Расширенная под вакуумом сухая композиция и шприц для ее сохранения |
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CN107206165B (zh) | 2014-12-24 | 2020-10-23 | 弗罗桑医疗设备公司 | 用于保持并混合第一和第二物质的注射器 |
EP3270985B1 (de) | 2015-03-19 | 2021-02-24 | The Brigham and Women's Hospital, Inc. | Polypeptidzusammensetzungen und verfahren zur verwendung davon |
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CN108495658B (zh) | 2015-09-01 | 2021-09-03 | 巴克斯特国际公司 | 止血材料 |
JP6887435B2 (ja) | 2016-02-08 | 2021-06-16 | ザ ブリガム アンド ウィメンズ ホスピタル インコーポレイテッドThe Brigham and Women’s Hospital, Inc. | 角膜修復のための生体接着剤 |
CN105879109A (zh) * | 2016-03-31 | 2016-08-24 | 武汉华同信生物科技有限公司 | 一种医用胶粘剂及其制备方法 |
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JP7173447B2 (ja) | 2017-11-03 | 2022-11-16 | バクスター・インターナショナル・インコーポレイテッド | ポリマー組成物、送達デバイス、及び方法 |
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CN116744983A (zh) | 2021-01-08 | 2023-09-12 | 西拉格国际有限公司 | 生物可吸收性密封粉末 |
CN113144277B (zh) * | 2021-04-13 | 2022-06-14 | 武汉理工大学 | 一种可注射流体明胶及其制备方法和应用 |
CN113209357B (zh) * | 2021-05-14 | 2023-02-17 | 南方科技大学 | 复合止血粉 |
CN117940173A (zh) * | 2021-09-16 | 2024-04-26 | 爱惜康股份有限公司 | 用于组织道密封的组合物的试剂盒 |
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