DE69915301D1 - Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate - Google Patents

Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate

Info

Publication number
DE69915301D1
DE69915301D1 DE69915301T DE69915301T DE69915301D1 DE 69915301 D1 DE69915301 D1 DE 69915301D1 DE 69915301 T DE69915301 T DE 69915301T DE 69915301 T DE69915301 T DE 69915301T DE 69915301 D1 DE69915301 D1 DE 69915301D1
Authority
DE
Germany
Prior art keywords
sucralfate
grainy
producing
gel composition
dry gel
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69915301T
Other languages
English (en)
Other versions
DE69915301T2 (de
Inventor
Giorgio Zagnoli
Paolo Colombo
Loretta Maggi
Fabrizio Cudazzo
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
D.R. DRUG RESEARCH S.R.L., ERBA, IT
Original Assignee
Lisapharma SpA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lisapharma SpA filed Critical Lisapharma SpA
Publication of DE69915301D1 publication Critical patent/DE69915301D1/de
Application granted granted Critical
Publication of DE69915301T2 publication Critical patent/DE69915301T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2086—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat
    • A61K9/209—Layered tablets, e.g. bilayer tablets; Tablets of the type inert core-active coat containing drug in at least two layers or in the core and in at least one outer layer

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DE69915301T 1998-07-30 1999-06-04 Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate Expired - Fee Related DE69915301T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
ITMI981785 1998-07-30
IT1998MI001785A IT1301969B1 (it) 1998-07-30 1998-07-30 Sucralfato gel secco granulare e poroso procedimento per la suapreparazione, e composizioni farmaceutiche solide che lo contengono
PCT/EP1999/003879 WO2000006201A1 (en) 1998-07-30 1999-06-04 Process for the preparation of granular and porous sucralfate dry gel

Publications (2)

Publication Number Publication Date
DE69915301D1 true DE69915301D1 (de) 2004-04-08
DE69915301T2 DE69915301T2 (de) 2005-03-10

Family

ID=11380570

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69915301T Expired - Fee Related DE69915301T2 (de) 1998-07-30 1999-06-04 Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate

Country Status (9)

Country Link
US (2) US6706286B1 (de)
EP (1) EP1100540B1 (de)
AT (1) ATE260676T1 (de)
AU (1) AU4506999A (de)
DE (1) DE69915301T2 (de)
ES (1) ES2217766T3 (de)
IT (1) IT1301969B1 (de)
PT (1) PT1100540E (de)
WO (1) WO2000006201A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
HUP0300491A2 (en) * 2000-02-28 2003-07-28 Vectura Ltd Improvements in or relating to the delivery of oral drugs
US10716802B2 (en) 2013-03-15 2020-07-21 The Brigham And Women's Hospital, Inc. Compounds to modulate intestinal absorption of nutrients
US10973846B2 (en) 2015-09-24 2021-04-13 The Brigham And Women's Hospital, Inc. Water-activated mucoadhesive compositions to reduce intestinal absorption of nutrients
KR101749425B1 (ko) * 2015-11-17 2017-06-22 연세대학교 산학협력단 난용성 약물의 서방형 제제
JP6855732B2 (ja) * 2016-09-29 2021-04-07 ライオン株式会社 粉体組成物及びその製造方法
CN109431972B (zh) * 2018-11-20 2022-02-22 昆明积大制药股份有限公司 一种粒径为100nm—500nm的硫糖铝凝胶的成胶方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1196190B (it) * 1984-07-12 1988-11-10 Lisapharma Spa Forma farmaceutica solida orale ad azione sequenziale per la somministrazione di farmaci ad effetto collaterale ulcerogeno
IT1203901B (it) * 1987-04-15 1989-02-23 Lisapharma Spa Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti
IT1274735B (it) * 1994-08-25 1997-07-24 Enosys S P A Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco
US5585115A (en) * 1995-01-09 1996-12-17 Edward H. Mendell Co., Inc. Pharmaceutical excipient having improved compressability

Also Published As

Publication number Publication date
WO2000006201A1 (en) 2000-02-10
IT1301969B1 (it) 2000-07-20
US20030206950A1 (en) 2003-11-06
AU4506999A (en) 2000-02-21
ITMI981785A0 (it) 1998-07-30
EP1100540A1 (de) 2001-05-23
ATE260676T1 (de) 2004-03-15
ES2217766T3 (es) 2004-11-01
PT1100540E (pt) 2004-07-30
DE69915301T2 (de) 2005-03-10
US6706286B1 (en) 2004-03-16
ITMI981785A1 (it) 2000-01-30
US6773722B2 (en) 2004-08-10
EP1100540B1 (de) 2004-03-03

Similar Documents

Publication Publication Date Title
ATE65386T1 (de) Verwendung von poroesen fuellstoffen in polymerisierbaren dentalmassen, solche massen und deren verwendung zur herstellung von formkoerpern.
DE69704426T2 (de) Verfahren zur herstellung von medizinischem kaugummi mit einem guten geschmack, enthaltend eine einschlussverbindung
ATE79023T1 (de) Formulierung zur oralen arzneistoffabgabe, sowie verfahren zu deren herstellung.
DE60230079D1 (de) Trockene hämostatische Zusammensetzungen und Verfahren zu ihrer Herstellung
DE3060801D1 (en) 4-substituted-3-hydroxy-3-pyrroline-2,5-dione compounds, process for their preparation and pharmaceutical compositions containing the same
DE60020716D1 (de) Filmbildende zusammensetzungen aus pullulan
CA2277913A1 (en) New formulation for inhalation having a poured bulk density of 0.28 to 0.38 g/ml, a process for preparing the formulation and the use thereof
NZ301695A (en) use of aerogels which has been surface modified by silylation as carrier materials in agricultural and veterinary compositions
BR9306443A (pt) Plaquetas de sangue humano fixas e secas farmaceuticamento aceitáveis
DE69921941D1 (de) Verfahren zur Herstellung von pharmazeutischen Wirkstoffpartikeln
ATE2271T1 (de) 4-(substituierte thiazolyl)-3-hydroxy-3-pyrrolin2,5-dion-verbindungen, verfahren zur herstellung und sie enthaltende pharmazeutische zusammensetzung.
EE03039B1 (et) Meetod hüdrateeritud tsefalosporiini kuiva pulbrilise segu valmistamiseks, sellel meetodil valmistatud segu ja farmatseutilised kompositsioonid
AU8452991A (en) 1-aryl-3-pyridinyl-2-propene-1-ones
NO175406C (no) Fremgangsmåte ved fremstilling av piroxam i vandig opplösning
ATE268172T1 (de) Verfahren zur herstellung von fenofibrat- präparaten
DE69821119D1 (de) Neuartige formulierung zur inhalation mit einer bulkdichte zwischen 0.28 und 0.38 g/ml, mit formoterol
DE69915301D1 (de) Verfahren zur herstellung einer körnigen porösen trockenen gelzusammensetzung von sucralfate
ATE215817T1 (de) Feste miltefosin enthaltende arzneimittel zur oralen verabreichung bei der behandlung von leishmaniasis
ATE71808T1 (de) Verfahren zur herstellung von produkten mit kontrollierter freigabe fuer kaugummi.
GR1002034B (en) Process for the preparation of dry processed particles dry processed particles thus obtained and pharmaceutical compositions containing such particles.
HUT37857A (en) Insectide compositions containing cyclodextrin inclusion complex as active substance and process for preparing the active substances
JPS57118511A (en) Gradually releasing preparation
NO882255D0 (no) Fremgangsmaate for fremstilling av olefinmaleinsyreanhydrid-kopolymer i form av partikler.
NO913683L (no) Fremgangsmaate for fremstilling av kalsiumopptaksinhibitorer.
AU8452791A (en) 1-phenyl-3-aryl-2-propyne-1-ones

Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8327 Change in the person/name/address of the patent owner

Owner name: D.R. DRUG RESEARCH S.R.L., ERBA, IT

8339 Ceased/non-payment of the annual fee