IT1274735B - Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco - Google Patents
Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel seccoInfo
- Publication number
- IT1274735B IT1274735B ITMI941775A ITMI941775A IT1274735B IT 1274735 B IT1274735 B IT 1274735B IT MI941775 A ITMI941775 A IT MI941775A IT MI941775 A ITMI941775 A IT MI941775A IT 1274735 B IT1274735 B IT 1274735B
- Authority
- IT
- Italy
- Prior art keywords
- sucralphate
- inflammatory
- drug
- vector
- state
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/70—Carbohydrates; Sugars; Derivatives thereof
- A61K31/7024—Esters of saccharides
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
- A61K47/26—Carbohydrates, e.g. sugar alcohols, amino sugars, nucleic acids, mono-, di- or oligo-saccharides; Derivatives thereof, e.g. polysorbates, sorbitan fatty acid esters or glycyrrhizin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1617—Organic compounds, e.g. phospholipids, fats
- A61K9/1623—Sugars or sugar alcohols, e.g. lactose; Derivatives thereof; Homeopathic globules
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- General Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Biophysics (AREA)
- Biochemistry (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Abstract
Si descrive un procedimento che consente di preparare sucralfato gel allo stato secco senza che esso perda le proprietà colloidali. inoltre, in considerazione del particolare tropismo di sucralfato gel verso la mucosa gastrica e delle sue proprietà di bioadesione, viene anche rivendicato l'uso di sucralfato gel secco come vettore per farmaci destinati al trattamento delle infezioni di Helicobacter pylori come antibiotici, antibatterici, antiinfiammatori, oppure per mantenere il più a lungo possibile nell'ambiente gastrico farmaci antisecretori come cimetidina, ranitidina, prostaglandine, omeprazolo.
Priority Applications (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI941775A IT1274735B (it) | 1994-08-25 | 1994-08-25 | Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco |
PCT/EP1995/003189 WO1996005843A1 (en) | 1994-08-25 | 1995-08-11 | Pharmaceutical compositions comprising co-dried sucralfate gel and polyalcohol |
EP95930446A EP0769953A1 (en) | 1994-08-25 | 1995-08-11 | Pharmaceutical compositions comprising co-dried sucralfate gel and polyalcohol |
AU33831/95A AU3383195A (en) | 1994-08-25 | 1995-08-11 | Pharmaceutical compositions comprising co-dried sucralfate gel and polyalcohol |
JP8507751A JPH10505822A (ja) | 1994-08-25 | 1995-08-11 | 共−乾燥されたスクラルファートゲル及びポリアルコールを含む製薬学的組成物 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ITMI941775A IT1274735B (it) | 1994-08-25 | 1994-08-25 | Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco |
Publications (3)
Publication Number | Publication Date |
---|---|
ITMI941775A0 ITMI941775A0 (it) | 1994-08-25 |
ITMI941775A1 ITMI941775A1 (it) | 1996-02-25 |
IT1274735B true IT1274735B (it) | 1997-07-24 |
Family
ID=11369491
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ITMI941775A IT1274735B (it) | 1994-08-25 | 1994-08-25 | Farmaco e vettore per le patologie infiammatorie ed erosive del tratto gastrointestinale a base di sucralfato allo stato di gel secco |
Country Status (5)
Country | Link |
---|---|
EP (1) | EP0769953A1 (it) |
JP (1) | JPH10505822A (it) |
AU (1) | AU3383195A (it) |
IT (1) | IT1274735B (it) |
WO (1) | WO1996005843A1 (it) |
Families Citing this family (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1999033470A1 (fr) * | 1997-12-25 | 1999-07-08 | Toray Industries, Inc. | ANTI $i(HELICOBACTER PYLORI) |
IT1301969B1 (it) | 1998-07-30 | 2000-07-20 | Lisapharma Spa | Sucralfato gel secco granulare e poroso procedimento per la suapreparazione, e composizioni farmaceutiche solide che lo contengono |
WO2005042026A1 (ja) * | 2003-10-31 | 2005-05-12 | Wakamoto Pharmaceutical Co., Ltd. | 可逆性熱ゲル化水性組成物 |
JP2006176461A (ja) * | 2004-12-24 | 2006-07-06 | Dai Ichi Seiyaku Co Ltd | 粒状物 |
FR2927808B1 (fr) * | 2008-02-26 | 2011-04-29 | Fabre Pierre Dermo Cosmetique | Gel de sucralfate sterilise |
WO2023042900A1 (ja) * | 2021-09-17 | 2023-03-23 | 富士化学工業株式会社 | スクラルファート含有ゼリー状医薬組成物 |
Family Cites Families (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IT1203901B (it) * | 1987-04-15 | 1989-02-23 | Lisapharma Spa | Composizioni farmaceutiche sotto forma di sospensioni stabili di sucralfato esenti da agenti sospendenti |
US5013557A (en) * | 1989-10-03 | 1991-05-07 | Warner-Lambert Company | Taste masking compositions comprising spray dried microcapsules containing sucralfate and methods for preparing same |
AU665944B2 (en) * | 1991-04-04 | 1996-01-25 | Procter & Gamble Company, The | Chewable antacid compositions |
-
1994
- 1994-08-25 IT ITMI941775A patent/IT1274735B/it active IP Right Grant
-
1995
- 1995-08-11 JP JP8507751A patent/JPH10505822A/ja active Pending
- 1995-08-11 WO PCT/EP1995/003189 patent/WO1996005843A1/en not_active Application Discontinuation
- 1995-08-11 AU AU33831/95A patent/AU3383195A/en not_active Abandoned
- 1995-08-11 EP EP95930446A patent/EP0769953A1/en not_active Withdrawn
Also Published As
Publication number | Publication date |
---|---|
ITMI941775A0 (it) | 1994-08-25 |
WO1996005843A1 (en) | 1996-02-29 |
JPH10505822A (ja) | 1998-06-09 |
EP0769953A1 (en) | 1997-05-02 |
ITMI941775A1 (it) | 1996-02-25 |
AU3383195A (en) | 1996-03-14 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
0001 | Granted | ||
TA | Fee payment date (situation as of event date), data collected since 19931001 |
Effective date: 19970828 |