IT1262993B - Complesso di bismuto citrato di ranitidina ed antibiotico, composizione che lo contiene e relativo metodo di produzione ed impiego - Google Patents

Complesso di bismuto citrato di ranitidina ed antibiotico, composizione che lo contiene e relativo metodo di produzione ed impiego

Info

Publication number
IT1262993B
IT1262993B ITRM920681A ITRM920681A IT1262993B IT 1262993 B IT1262993 B IT 1262993B IT RM920681 A ITRM920681 A IT RM920681A IT RM920681 A ITRM920681 A IT RM920681A IT 1262993 B IT1262993 B IT 1262993B
Authority
IT
Italy
Prior art keywords
ritnitine
bismuto
antibiotic
production
composition containing
Prior art date
Application number
ITRM920681A
Other languages
English (en)
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ITRM920681A0 publication Critical patent/ITRM920681A0/it
Publication of ITRM920681A1 publication Critical patent/ITRM920681A1/it
Application granted granted Critical
Publication of IT1262993B publication Critical patent/IT1262993B/it

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)

Abstract

E' descritto l'impiego sia di (i) bismuto citrato di ranitidina che (ii) di uno o più antibiotici che inibiscono Helicobacter pylori nel trattamento o prevenzione di disturbi gastrointestinali.Sono descritti anche composizioni farmaceutiche contenenti sia (i) che (ii) e metodi per la preparazione di composizioni farmaceutiche contenenti (i) e (ii).
ITRM920681A 1991-09-20 1992-09-18 Complesso di bismuto citrato di ranitidina ed antibiotico, composizione che lo contiene e relativo metodo di produzione ed impiego IT1262993B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919120131A GB9120131D0 (en) 1991-09-20 1991-09-20 Medicaments

Publications (3)

Publication Number Publication Date
ITRM920681A0 ITRM920681A0 (it) 1992-09-18
ITRM920681A1 ITRM920681A1 (it) 1994-03-18
IT1262993B true IT1262993B (it) 1996-07-23

Family

ID=10701750

Family Applications (1)

Application Number Title Priority Date Filing Date
ITRM920681A IT1262993B (it) 1991-09-20 1992-09-18 Complesso di bismuto citrato di ranitidina ed antibiotico, composizione che lo contiene e relativo metodo di produzione ed impiego

Country Status (26)

Country Link
US (3) US5668130A (it)
EP (1) EP0533281B1 (it)
JP (1) JPH0692850A (it)
KR (1) KR100257367B1 (it)
AT (2) ATE228835T1 (it)
BE (1) BE1005808A5 (it)
CA (1) CA2078579A1 (it)
CH (1) CH685372A5 (it)
CY (1) CY2012A (it)
CZ (1) CZ282840B6 (it)
DE (1) DE69232864T2 (it)
ES (1) ES2188582T3 (it)
FR (1) FR2682040B1 (it)
GB (2) GB9120131D0 (it)
HK (1) HK78197A (it)
HU (1) HU211170A9 (it)
IE (1) IE922673A1 (it)
IL (1) IL103213A (it)
IT (1) IT1262993B (it)
MX (1) MX9205313A (it)
NO (1) NO301456B1 (it)
NZ (1) NZ244390A (it)
PT (1) PT533281E (it)
RU (1) RU2116071C1 (it)
SK (1) SK280283B6 (it)
ZA (1) ZA927157B (it)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0402473B1 (en) * 1988-10-31 1994-05-11 Sumitomo Cement Co. Ltd. Antireflection articles, process for their production and coating composition
JPH08506353A (ja) * 1993-06-15 1996-07-09 フアイザー・インコーポレイテツド ウシもしくはブタの細菌感染における免疫刺激剤としてのh2−拮抗剤
EP0642797B1 (en) * 1993-09-09 2000-05-17 Takeda Chemical Industries, Ltd. Formulation comprising antibacterial substance and antiulcer substance
TW420610B (en) * 1994-04-07 2001-02-01 Pfizer A pharmaceutical composition for treating a H. pylori infection or gastric or duodenal ulcers
KR970702725A (ko) * 1994-04-26 1997-06-10 노부히로 나리따 비소세포 폐암 치료용 의약 조성물(Medicinal Composition as a Remedy for Nonsmall Cell Lung Cancer)
GB9501560D0 (en) 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
HUP9900428A2 (hu) * 1995-01-26 1999-06-28 Nycomed Imaging A/S Bizmutvegyületek, ezeket tartalmazó diagnosztikai kontrasztanyag, ennek alkalmazása és ezt tartalmazó gyógyászati készítmény
US5981522A (en) * 1995-09-01 1999-11-09 Kaneka Corporation Treatment of disease caused by infection of Helicobacter
KR970032861A (ko) * 1995-12-29 1997-07-22 김준웅 헬리코박터 피로리 제거용 약제 투여방법
US5900410A (en) * 1996-08-27 1999-05-04 Hartmann; John F. Monotherapy of peptic ulcers and gastritis
DE19709897A1 (de) * 1997-03-11 1998-09-17 Hoechst Ag Wismutsalze von Antibiotika der Moenomycin-Gruppe, Verfahren zu ihrer Herstellung, ihre Verwendung und solche Salze enthaltende Arzneimittel
US6017950A (en) * 1997-08-05 2000-01-25 Millennium Pharmaceuticals, Inc. Methods for controlling gram negative bacteria in mammals
IT1296980B1 (it) * 1997-12-17 1999-08-03 Istituto Pirri S R L Capsula doppia come forma farmaceutica per la somministrazione di principi attivi in terapie multiple
AU3668000A (en) * 1999-04-29 2000-11-17 Russinsky Limited Compounds
WO2001064224A1 (en) * 2000-02-29 2001-09-07 Teva Pharmaceutical Industries Ltd. Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
EP1603554A1 (en) 2003-03-17 2005-12-14 Japan Tobacco Inc. Method for increasing the oral bioavailability of s-[2-([[1-(2-ethylbutyl)cyclohexyl]carbonyl]amino)phenyl]-2-methylpropanethioate
US20060194748A1 (en) * 2005-02-28 2006-08-31 National University Corporation Nagoya University Methods for treating disorders induced by H. pylori infections and pharmaceutical compositions for the same
CA2886042C (en) 2012-09-28 2015-11-24 Santen Pharmaceutical Co., Ltd. Therapeutic or preventive agent for meibomian gland dysfunction or meibomian gland blockage
US10201518B2 (en) 2016-09-28 2019-02-12 The University Of Hong Kong Bismuth(III) compounds and methods thereof
WO2020045807A1 (ko) 2018-08-31 2020-03-05 한국지질자원연구원 비흡수성 항생물질 및 점토광물의 복합체를 포함하는 조성물을 대상에게 경구투여하는 단계를 포함하는 헬리코박터 파일로리의 제균 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB772567A (en) * 1954-05-06 1957-04-17 Siegfried Fischl Preparation of stable, injectable bismuth-containing pharmaceutical compositions and the compositions formed thereby
AU590578B2 (en) * 1985-04-18 1989-11-09 Procter & Gamble Company, The Treatment of non-ulcer dyspepsia with bismuth salts
ATE318144T1 (de) * 1985-06-13 2006-03-15 Barry James Marshall Pharmazeutische zusammensetzung zur behandlung gastrointestinaler beschwerden, die wismut und ein antimikrobielles mittel enthält
US5256684A (en) * 1985-06-13 1993-10-26 The Procter & Gamble Company Methods and compositions for the treatment of gastrointestinal disorders
US4959384A (en) * 1985-10-24 1990-09-25 Norwich Eaton Pharmaceuticals, Inc. Use of nitrofurantoin for the treatment and prophylaxis of gastrointestinal disorders
IL85472A (en) * 1987-03-09 1991-06-30 Procter & Gamble Pharmaceutical compositions for treating gastrointestinal disorders
ATE81011T1 (de) * 1987-03-09 1992-10-15 Procter & Gamble Zusammensetzungen und ihre verwendung zur behandlung von magen-darmstoerungen.
JP2733849B2 (ja) * 1987-10-12 1998-03-30 ボロディー,ソーマス・ユリウス 胃腸障害治療のための改良された方法
CH679582A5 (it) * 1988-07-18 1992-03-13 Glaxo Group Ltd
FI910088A (fi) * 1990-01-09 1991-07-10 Gist Brocades Nv Oral farmaceutisk komposition.
YU45590A (sh) * 1990-03-07 1992-07-20 PLIVA FARMACEVTSKA, KEMIJSKA, PREHRAMBENA I KOZMETIČKA INDUSTRIJA s.p.o. Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje
GB9019875D0 (en) * 1990-09-11 1990-10-24 Glaxo Group Ltd Pharmaceutical compositions
AU8941891A (en) * 1990-12-04 1992-07-08 Anton Jenni Sprinkler installation for the floors of riding halls, hothouses, etc.
US5176698A (en) * 1991-01-09 1993-01-05 Scimed Life Systems, Inc. Vented dilatation cathether and method for venting
US5128140A (en) * 1991-01-14 1992-07-07 The Procter & Gamble Company Swallowable pharmaceutical compositions

Also Published As

Publication number Publication date
IL103213A (en) 2000-02-29
US5668130A (en) 1997-09-16
ZA927157B (en) 1993-06-15
SK280283B6 (sk) 1999-11-08
GB9219749D0 (en) 1992-10-28
MX9205313A (es) 1993-04-01
AU663520B2 (en) 1995-10-12
KR930005619A (ko) 1993-04-20
ES2188582T3 (es) 2003-07-01
DE69232864D1 (de) 2003-01-16
GB9120131D0 (en) 1991-11-06
ITRM920681A1 (it) 1994-03-18
ITRM920681A0 (it) 1992-09-18
GB2259647B (en) 1995-11-29
AT403656B (de) 1998-04-27
US5629297A (en) 1997-05-13
HK78197A (en) 1997-06-20
CH685372A5 (fr) 1995-06-30
ATA186692A (de) 1997-09-15
CZ282840B6 (cs) 1997-10-15
KR100257367B1 (ko) 2000-05-15
AU2458492A (en) 1993-03-25
SK287892A3 (en) 1995-06-07
NO301456B1 (no) 1997-11-03
IE922673A1 (en) 1993-03-24
NO923643D0 (no) 1992-09-18
EP0533281B1 (en) 2002-12-04
NZ244390A (en) 1997-06-24
NO923643L (no) 1993-03-22
CZ287892A3 (en) 1993-12-15
CA2078579A1 (en) 1993-03-21
PT533281E (pt) 2003-04-30
GB2259647A (en) 1993-03-24
CY2012A (en) 1998-02-20
JPH0692850A (ja) 1994-04-05
FR2682040B1 (fr) 1994-10-28
RU2116071C1 (ru) 1998-07-27
FR2682040A1 (fr) 1993-04-09
ATE228835T1 (de) 2002-12-15
DE69232864T2 (de) 2003-11-20
EP0533281A1 (en) 1993-03-24
IL103213A0 (en) 1993-02-21
US5674858A (en) 1997-10-07
BE1005808A5 (fr) 1994-02-01
HU211170A9 (en) 1995-11-28

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TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19970929