DE69232864D1 - Verwendung von Ranitidin-Wismut-Zitrat in Kombination mit Claritromyzin oder Claritromyzin und Tetrazyklin zur Herstellung eines Arzneimittels zur Behandlung gastrointestinaler Beschwerden - Google Patents

Verwendung von Ranitidin-Wismut-Zitrat in Kombination mit Claritromyzin oder Claritromyzin und Tetrazyklin zur Herstellung eines Arzneimittels zur Behandlung gastrointestinaler Beschwerden

Info

Publication number
DE69232864D1
DE69232864D1 DE69232864T DE69232864T DE69232864D1 DE 69232864 D1 DE69232864 D1 DE 69232864D1 DE 69232864 T DE69232864 T DE 69232864T DE 69232864 T DE69232864 T DE 69232864T DE 69232864 D1 DE69232864 D1 DE 69232864D1
Authority
DE
Germany
Prior art keywords
claritromycin
tetracycline
medicament
manufacture
treatment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69232864T
Other languages
English (en)
Other versions
DE69232864T2 (de
Inventor
Andrew Alexander Mccolm
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Application granted granted Critical
Publication of DE69232864D1 publication Critical patent/DE69232864D1/de
Publication of DE69232864T2 publication Critical patent/DE69232864T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/54Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame
    • A61K31/542Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one sulfur as the ring hetero atoms, e.g. sulthiame ortho- or peri-condensed with heterocyclic ring systems
    • A61K31/545Compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins, cefaclor, or cephalexine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/335Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/34Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having five-membered rings with one oxygen as the only ring hetero atom, e.g. isosorbide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/4151,2-Diazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/41Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
    • A61K31/425Thiazoles
    • A61K31/429Thiazoles condensed with heterocyclic ring systems
    • A61K31/43Compounds containing 4-thia-1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula, e.g. penicillins, penems
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/65Tetracyclines
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/70Carbohydrates; Sugars; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K45/00Medicinal preparations containing active ingredients not provided for in groups A61K31/00 - A61K41/00
    • A61K45/06Mixtures of active ingredients without chemical characterisation, e.g. antiphlogistics and cardiaca
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P33/00Antiparasitic agents
    • A61P33/02Antiprotozoals, e.g. for leishmaniasis, trichomoniasis, toxoplasmosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
DE69232864T 1991-09-20 1992-09-16 Verwendung von Ranitidin-Wismut-Zitrat in Kombination mit Claritromyzin oder Claritromyzin und Tetrazyklin zur Herstellung eines Arzneimittels zur Behandlung gastrointestinaler Beschwerden Expired - Fee Related DE69232864T2 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB919120131A GB9120131D0 (en) 1991-09-20 1991-09-20 Medicaments

Publications (2)

Publication Number Publication Date
DE69232864D1 true DE69232864D1 (de) 2003-01-16
DE69232864T2 DE69232864T2 (de) 2003-11-20

Family

ID=10701750

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69232864T Expired - Fee Related DE69232864T2 (de) 1991-09-20 1992-09-16 Verwendung von Ranitidin-Wismut-Zitrat in Kombination mit Claritromyzin oder Claritromyzin und Tetrazyklin zur Herstellung eines Arzneimittels zur Behandlung gastrointestinaler Beschwerden

Country Status (26)

Country Link
US (3) US5674858A (de)
EP (1) EP0533281B1 (de)
JP (1) JPH0692850A (de)
KR (1) KR100257367B1 (de)
AT (2) ATE228835T1 (de)
BE (1) BE1005808A5 (de)
CA (1) CA2078579A1 (de)
CH (1) CH685372A5 (de)
CY (1) CY2012A (de)
CZ (1) CZ282840B6 (de)
DE (1) DE69232864T2 (de)
ES (1) ES2188582T3 (de)
FR (1) FR2682040B1 (de)
GB (2) GB9120131D0 (de)
HK (1) HK78197A (de)
HU (1) HU211170A9 (de)
IE (1) IE922673A1 (de)
IL (1) IL103213A (de)
IT (1) IT1262993B (de)
MX (1) MX9205313A (de)
NO (1) NO301456B1 (de)
NZ (1) NZ244390A (de)
PT (1) PT533281E (de)
RU (1) RU2116071C1 (de)
SK (1) SK280283B6 (de)
ZA (1) ZA927157B (de)

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Publication number Priority date Publication date Assignee Title
DE68915272T2 (de) * 1988-10-31 1994-11-17 Sumitomo Cement Co Antireflexionsgegenstände, herstellungsverfahren und beschichtungszusammensetzungen.
AU6436394A (en) * 1993-06-15 1995-01-03 Pfizer Inc. H2-antagonists as immune stimulants in bacterial infections of cattle or swine
EP0995447A1 (de) * 1993-09-09 2000-04-26 Takeda Chemical Industries, Ltd. Formulierung enthaltend einen Antibakteriellen und einen Antiulcus Wirkstoff
TW420610B (en) * 1994-04-07 2001-02-01 Pfizer A pharmaceutical composition for treating a H. pylori infection or gastric or duodenal ulcers
EP0758549A4 (de) * 1994-04-26 1997-07-02 Nobuhiro Narita Medizinische zusammensetzung als medikament gegen nicht kleinzelligen lungenkrebs
HUP9900428A2 (hu) * 1995-01-26 1999-06-28 Nycomed Imaging A/S Bizmutvegyületek, ezeket tartalmazó diagnosztikai kontrasztanyag, ennek alkalmazása és ezt tartalmazó gyógyászati készítmény
GB9501560D0 (en) * 1995-01-26 1995-03-15 Nycomed Imaging As Contrast agents
US5981522A (en) * 1995-09-01 1999-11-09 Kaneka Corporation Treatment of disease caused by infection of Helicobacter
KR970032861A (ko) * 1995-12-29 1997-07-22 김준웅 헬리코박터 피로리 제거용 약제 투여방법
US5900410A (en) * 1996-08-27 1999-05-04 Hartmann; John F. Monotherapy of peptic ulcers and gastritis
DE19709897A1 (de) * 1997-03-11 1998-09-17 Hoechst Ag Wismutsalze von Antibiotika der Moenomycin-Gruppe, Verfahren zu ihrer Herstellung, ihre Verwendung und solche Salze enthaltende Arzneimittel
US6017950A (en) * 1997-08-05 2000-01-25 Millennium Pharmaceuticals, Inc. Methods for controlling gram negative bacteria in mammals
IT1296980B1 (it) * 1997-12-17 1999-08-03 Istituto Pirri S R L Capsula doppia come forma farmaceutica per la somministrazione di principi attivi in terapie multiple
AU3668000A (en) * 1999-04-29 2000-11-17 Russinsky Limited Compounds
AU2578701A (en) * 2000-02-29 2001-09-12 Teva Pharma Processes for preparing clarithromycin and clarithromycin intermediate, essentially oxime-free clarithromycin, and pharmaceutical composition comprising the same
US7670612B2 (en) 2002-04-10 2010-03-02 Innercap Technologies, Inc. Multi-phase, multi-compartment capsular delivery apparatus and methods for using same
BRPI0408442A (pt) 2003-03-17 2006-04-04 Japan Tobacco Inc método para aumento da biodisponibilidade oral de s-[2-([[1-(2-etilbutil)ciclohexil]carbonil]amino)fenil]2- metilpropanotioato
US20060194748A1 (en) * 2005-02-28 2006-08-31 National University Corporation Nagoya University Methods for treating disorders induced by H. pylori infections and pharmaceutical compositions for the same
EP2902023A4 (de) 2012-09-28 2016-03-30 Santen Pharmaceutical Co Ltd Therapeutikum oder prophylaktikum für meibomdrüsendysfunktion oder meibomdrüsenblockierung
US10201518B2 (en) 2016-09-28 2019-02-12 The University Of Hong Kong Bismuth(III) compounds and methods thereof
WO2020045807A1 (ko) 2018-08-31 2020-03-05 한국지질자원연구원 비흡수성 항생물질 및 점토광물의 복합체를 포함하는 조성물을 대상에게 경구투여하는 단계를 포함하는 헬리코박터 파일로리의 제균 방법

Family Cites Families (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB772567A (en) * 1954-05-06 1957-04-17 Siegfried Fischl Preparation of stable, injectable bismuth-containing pharmaceutical compositions and the compositions formed thereby
WO1986005981A1 (en) * 1985-04-18 1986-10-23 Borody Thomas J Treatment of non-ulcer dyspepsia with bismuth salts
US5256684A (en) * 1985-06-13 1993-10-26 The Procter & Gamble Company Methods and compositions for the treatment of gastrointestinal disorders
DE3686836T2 (de) * 1985-06-13 1993-03-04 Marshall Barry James Zusammensetzungen zur behandlung von magen-darmstoerungen.
US4959384A (en) * 1985-10-24 1990-09-25 Norwich Eaton Pharmaceuticals, Inc. Use of nitrofurantoin for the treatment and prophylaxis of gastrointestinal disorders
DE3874917T2 (de) * 1987-03-09 1993-03-04 Procter & Gamble Zusammensetzungen und ihre verwendung zur behandlung von magen-darmstoerungen.
IL85472A (en) * 1987-03-09 1991-06-30 Procter & Gamble Pharmaceutical compositions for treating gastrointestinal disorders
EP0439453B1 (de) * 1987-10-12 1994-01-19 Exomed Australia Pty. Ltd. (ACN 051 976 446) Behandlungsverfahren für magen-darm-krankheiten
CH679582A5 (de) * 1988-07-18 1992-03-13 Glaxo Group Ltd
FI910088A (fi) * 1990-01-09 1991-07-10 Gist Brocades Nv Oral farmaceutisk komposition.
YU45590A (sh) * 1990-03-07 1992-07-20 PLIVA FARMACEVTSKA, KEMIJSKA, PREHRAMBENA I KOZMETIČKA INDUSTRIJA s.p.o. Novi kompleksi odnosno helati antibiotika s dvovalentnim i/ili trovalentnim metalima i postupci za njihovo dobijanje
GB9019875D0 (en) * 1990-09-11 1990-10-24 Glaxo Group Ltd Pharmaceutical compositions
AU8941891A (en) * 1990-12-04 1992-07-08 Anton Jenni Sprinkler installation for the floors of riding halls, hothouses, etc.
US5176698A (en) * 1991-01-09 1993-01-05 Scimed Life Systems, Inc. Vented dilatation cathether and method for venting
US5128140A (en) * 1991-01-14 1992-07-07 The Procter & Gamble Company Swallowable pharmaceutical compositions

Also Published As

Publication number Publication date
ATA186692A (de) 1997-09-15
IL103213A (en) 2000-02-29
IT1262993B (it) 1996-07-23
IE922673A1 (en) 1993-03-24
US5629297A (en) 1997-05-13
NO923643D0 (no) 1992-09-18
SK280283B6 (sk) 1999-11-08
JPH0692850A (ja) 1994-04-05
DE69232864T2 (de) 2003-11-20
US5674858A (en) 1997-10-07
US5668130A (en) 1997-09-16
HU211170A9 (en) 1995-11-28
GB2259647B (en) 1995-11-29
ATE228835T1 (de) 2002-12-15
CA2078579A1 (en) 1993-03-21
FR2682040A1 (fr) 1993-04-09
AU2458492A (en) 1993-03-25
ES2188582T3 (es) 2003-07-01
CY2012A (en) 1998-02-20
CH685372A5 (fr) 1995-06-30
SK287892A3 (en) 1995-06-07
GB9120131D0 (en) 1991-11-06
IL103213A0 (en) 1993-02-21
FR2682040B1 (fr) 1994-10-28
NO923643L (no) 1993-03-22
CZ282840B6 (cs) 1997-10-15
CZ287892A3 (en) 1993-12-15
MX9205313A (es) 1993-04-01
GB2259647A (en) 1993-03-24
GB9219749D0 (en) 1992-10-28
EP0533281B1 (de) 2002-12-04
NZ244390A (en) 1997-06-24
KR100257367B1 (ko) 2000-05-15
AT403656B (de) 1998-04-27
NO301456B1 (no) 1997-11-03
ITRM920681A1 (it) 1994-03-18
KR930005619A (ko) 1993-04-20
ITRM920681A0 (it) 1992-09-18
ZA927157B (en) 1993-06-15
RU2116071C1 (ru) 1998-07-27
AU663520B2 (en) 1995-10-12
EP0533281A1 (de) 1993-03-24
BE1005808A5 (fr) 1994-02-01
PT533281E (pt) 2003-04-30
HK78197A (en) 1997-06-20

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