DE60205693T2 - Verfahren zur schnellen Synthese von Peptiden in Lösung - Google Patents
Verfahren zur schnellen Synthese von Peptiden in Lösung Download PDFInfo
- Publication number
- DE60205693T2 DE60205693T2 DE60205693T DE60205693T DE60205693T2 DE 60205693 T2 DE60205693 T2 DE 60205693T2 DE 60205693 T DE60205693 T DE 60205693T DE 60205693 T DE60205693 T DE 60205693T DE 60205693 T2 DE60205693 T2 DE 60205693T2
- Authority
- DE
- Germany
- Prior art keywords
- peptides
- solution
- rapid synthesis
- synthesis
- rapid
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
- C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Analytical Chemistry (AREA)
- Peptides Or Proteins (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP01202753 | 2001-07-19 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE60205693D1 DE60205693D1 (de) | 2005-09-29 |
| DE60205693T2 true DE60205693T2 (de) | 2006-06-14 |
Family
ID=8180656
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE60205693T Expired - Lifetime DE60205693T2 (de) | 2001-07-19 | 2002-07-15 | Verfahren zur schnellen Synthese von Peptiden in Lösung |
Country Status (25)
| Country | Link |
|---|---|
| US (4) | US20030018164A1 (enExample) |
| EP (1) | EP1291356B1 (enExample) |
| JP (1) | JP4142907B2 (enExample) |
| KR (1) | KR100861031B1 (enExample) |
| CN (1) | CN1254483C (enExample) |
| AR (1) | AR034869A1 (enExample) |
| AT (1) | ATE302792T1 (enExample) |
| BR (1) | BRPI0202783B1 (enExample) |
| CA (1) | CA2390358C (enExample) |
| DE (1) | DE60205693T2 (enExample) |
| DK (1) | DK1291356T3 (enExample) |
| EC (1) | ECSP024291A (enExample) |
| ES (1) | ES2248485T3 (enExample) |
| HR (1) | HRP20020609B1 (enExample) |
| HU (1) | HUP0202369A2 (enExample) |
| IL (1) | IL150601A (enExample) |
| MX (1) | MXPA02006998A (enExample) |
| NO (1) | NO324245B1 (enExample) |
| PE (1) | PE20030214A1 (enExample) |
| PL (1) | PL205559B1 (enExample) |
| PT (1) | PT1291356E (enExample) |
| RU (1) | RU2237673C2 (enExample) |
| SG (1) | SG119160A1 (enExample) |
| TW (1) | TWI247012B (enExample) |
| ZA (1) | ZA200205409B (enExample) |
Families Citing this family (21)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IL150601A (en) * | 2001-07-19 | 2010-06-30 | Organon Nv | Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component |
| EP1790656A1 (en) | 2005-11-25 | 2007-05-30 | Nanokem S.A. | Solution-phase synthesis of leuprolide |
| EP1801086A1 (en) * | 2005-11-25 | 2007-06-27 | Synthacon GmbH | Synthesis of carbon acid amides |
| US20090093016A1 (en) * | 2006-01-17 | 2009-04-09 | N.V. Organon | Selective Enzymatic Hydrolysis of C-Terminal Tert-Butyl Esters of Peptides |
| US8716439B2 (en) | 2006-03-01 | 2014-05-06 | Kaneka Corporation | Method of producing peptide |
| US8124372B2 (en) | 2007-06-25 | 2012-02-28 | N.V. Organon | Selective enzymatic amidation of C-terminal esters or acids of peptides |
| DE602008004350D1 (de) * | 2007-06-25 | 2011-02-17 | Organon Nv | Verfahren zur umsetzung von c-terminalen peptidestern oder -säuren zu amiden unter verwendung von subtilisin in gegenwart von ammoniumsalzen |
| RU2482127C2 (ru) * | 2008-12-30 | 2013-05-20 | Гкл-Биотек Аг | Комбинация пептидов |
| KR101032399B1 (ko) * | 2010-02-11 | 2011-05-03 | 주식회사 이너트론 | 밴드패스필터의 철재하우징 및 그 제조방법 |
| EP2409982A3 (en) * | 2010-02-25 | 2012-02-08 | Corning Incorporated | Chemical processes generating solid(s) carried out continuously within microreactors |
| WO2013089241A1 (ja) | 2011-12-15 | 2013-06-20 | 味の素株式会社 | Ｆｍｏｃ基の除去方法 |
| CN107406480B (zh) | 2015-03-04 | 2022-06-24 | Jitsubo株式会社 | 肽合成方法 |
| CA3009065C (en) | 2015-12-21 | 2022-01-25 | Texas Tech University System | System and method for solution phase gap peptide synthesis |
| CN111971293B (zh) | 2018-04-13 | 2024-07-30 | Jitsubo株式会社 | 肽合成方法 |
| US12024537B2 (en) | 2018-05-31 | 2024-07-02 | Sederma | Compositions and methods for chemical synthesis |
| FR3090636B1 (fr) * | 2018-12-24 | 2021-01-01 | Strainchem | Procédé de synthèse de peptides |
| CA3126705A1 (en) | 2019-02-01 | 2020-08-06 | Gap Peptides Llc | Synthesis strategy for gap protecting group |
| EP4023661B1 (en) * | 2019-08-30 | 2024-09-04 | Nissan Chemical Corporation | Method for producing peptide compound |
| WO2021132545A1 (ja) * | 2019-12-27 | 2021-07-01 | 中外製薬株式会社 | ペプチド化合物の合成法 |
| WO2021192488A1 (ja) * | 2020-03-27 | 2021-09-30 | 株式会社カネカ | アミド結合含有化合物の製造方法 |
| JP7063408B1 (ja) | 2021-07-02 | 2022-05-09 | ペプチスター株式会社 | 液相ペプチド製造方法 |
Family Cites Families (20)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US1991A (en) * | 1841-02-23 | Manner of fastening bedsteads | ||
| US5221754A (en) * | 1989-06-09 | 1993-06-22 | Research Corporation Technologies, Inc. | Reagents for rapid peptide synthesis |
| US5101059A (en) * | 1989-12-05 | 1992-03-31 | Research Corporation Technologies, Inc. | Amino acid protecting groups |
| US5877278A (en) | 1992-09-24 | 1999-03-02 | Chiron Corporation | Synthesis of N-substituted oligomers |
| US5516892A (en) | 1992-12-28 | 1996-05-14 | Indiana University Foundation | Polymer-bound mixed carboxylic anhdrides as a stable form of activated carboxylic acids |
| US6310180B1 (en) * | 1993-06-21 | 2001-10-30 | Vanderbilt University | Method for synthesis of proteins |
| US5516639A (en) * | 1993-07-22 | 1996-05-14 | Mayo Foundation For Medical Education And Research | Antibodies specific for human prostate glandular kallkrein |
| US6001966A (en) * | 1995-10-19 | 1999-12-14 | Proligo Llc | Method for solution phase synthesis of oligonucleotides and peptides |
| US5698676A (en) * | 1995-11-30 | 1997-12-16 | Abbott Laboratories | Use of propylene oxide as an acid scavenger in peptide synthesis |
| US5849954A (en) * | 1996-01-18 | 1998-12-15 | Research Corporation Technologies, Inc. | Method of peptide synthesis |
| US6306959B1 (en) | 1996-05-03 | 2001-10-23 | Warner Lambert Company | Rapid purification by polymer supported quench |
| US6121488A (en) * | 1997-09-24 | 2000-09-19 | Warner-Lambert Company | Quenching reagents for solution phase synthesis |
| JPH11217397A (ja) * | 1997-11-27 | 1999-08-10 | Saburo Aimoto | ペプチドチオールエステルの製造方法 |
| FR2780061B1 (fr) | 1998-06-22 | 2001-09-07 | Rhone Poulenc Rorer Sa | Nouveau procede de preparation de derives de cyclosporine |
| WO2000071569A1 (en) * | 1999-05-26 | 2000-11-30 | Abbott Laboratories | Minimal isolation peptide synthesis process using ion-exchange resins as scavenging agents |
| US20020127219A1 (en) | 1999-12-30 | 2002-09-12 | Okkels Jens Sigurd | Lysosomal enzymes and lysosomal enzyme activators |
| WO2002006306A2 (en) | 2000-07-19 | 2002-01-24 | Pharmacia & Upjohn Company | SUBSTRATES AND ASSAYS FOR β-SECRETASE ACTIVITY |
| TWI243826B (en) * | 2001-07-19 | 2005-11-21 | Akzo Nobel Nv | Process for the preparation of peptides |
| IL150601A (en) * | 2001-07-19 | 2010-06-30 | Organon Nv | Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component |
| US7510768B2 (en) * | 2005-06-17 | 2009-03-31 | Eastman Chemical Company | Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein |
-
2002
- 2002-07-04 IL IL150601A patent/IL150601A/en active IP Right Grant
- 2002-07-04 TW TW091114832A patent/TWI247012B/zh not_active IP Right Cessation
- 2002-07-05 ZA ZA200205409A patent/ZA200205409B/xx unknown
- 2002-07-05 JP JP2002197550A patent/JP4142907B2/ja not_active Expired - Lifetime
- 2002-07-15 EP EP02077830A patent/EP1291356B1/en not_active Expired - Lifetime
- 2002-07-15 PT PT02077830T patent/PT1291356E/pt unknown
- 2002-07-15 DE DE60205693T patent/DE60205693T2/de not_active Expired - Lifetime
- 2002-07-15 DK DK02077830T patent/DK1291356T3/da active
- 2002-07-15 ES ES02077830T patent/ES2248485T3/es not_active Expired - Lifetime
- 2002-07-15 AT AT02077830T patent/ATE302792T1/de active
- 2002-07-15 SG SG200204298A patent/SG119160A1/en unknown
- 2002-07-17 MX MXPA02006998A patent/MXPA02006998A/es active IP Right Grant
- 2002-07-17 PE PE2002000637A patent/PE20030214A1/es not_active Application Discontinuation
- 2002-07-18 NO NO20023446A patent/NO324245B1/no not_active IP Right Cessation
- 2002-07-18 AR ARP020102687A patent/AR034869A1/es active IP Right Grant
- 2002-07-18 RU RU2002119630/04A patent/RU2237673C2/ru not_active IP Right Cessation
- 2002-07-18 HU HU0202369A patent/HUP0202369A2/hu unknown
- 2002-07-18 CN CNB021261911A patent/CN1254483C/zh not_active Expired - Lifetime
- 2002-07-18 KR KR1020020041898A patent/KR100861031B1/ko not_active Expired - Fee Related
- 2002-07-18 CA CA002390358A patent/CA2390358C/en not_active Expired - Lifetime
- 2002-07-18 BR BRPI0202783A patent/BRPI0202783B1/pt active IP Right Grant
- 2002-07-19 EC EC2002004291A patent/ECSP024291A/es unknown
- 2002-07-19 PL PL355125A patent/PL205559B1/pl not_active IP Right Cessation
- 2002-07-19 US US10/199,805 patent/US20030018164A1/en not_active Abandoned
- 2002-07-19 HR HR20020609A patent/HRP20020609B1/xx not_active IP Right Cessation
-
2003
- 2003-10-22 US US10/692,354 patent/US20040082760A1/en not_active Abandoned
- 2003-10-23 US US10/693,123 patent/US20060063918A1/en not_active Abandoned
- 2003-10-23 US US10/693,802 patent/US7435791B2/en not_active Expired - Lifetime
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8327 | Change in the person/name/address of the patent owner |
Owner name: N.V. ORGANON, OSS, NL |
|
| R082 | Change of representative |
Ref document number: 1291356 Country of ref document: EP Representative=s name: WUESTHOFF & WUESTHOFF PATENT- UND RECHTSANWAEL, DE |