PT1291356E - Processo para uma rapida sintese de peptidos em solucao - Google Patents

Processo para uma rapida sintese de peptidos em solucao

Info

Publication number
PT1291356E
PT1291356E PT02077830T PT02077830T PT1291356E PT 1291356 E PT1291356 E PT 1291356E PT 02077830 T PT02077830 T PT 02077830T PT 02077830 T PT02077830 T PT 02077830T PT 1291356 E PT1291356 E PT 1291356E
Authority
PT
Portugal
Prior art keywords
peptides
solution
fast synthesis
synthesis
fast
Prior art date
Application number
PT02077830T
Other languages
English (en)
Portuguese (pt)
Inventor
Eggen Ivo Franci
Ten Kortenaar Paulus Wilhelmus
Haasnoot Cornelis Alber Gruson
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Publication of PT1291356E publication Critical patent/PT1291356E/pt

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
PT02077830T 2001-07-19 2002-07-15 Processo para uma rapida sintese de peptidos em solucao PT1291356E (pt)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202753 2001-07-19

Publications (1)

Publication Number Publication Date
PT1291356E true PT1291356E (pt) 2005-11-30

Family

ID=8180656

Family Applications (1)

Application Number Title Priority Date Filing Date
PT02077830T PT1291356E (pt) 2001-07-19 2002-07-15 Processo para uma rapida sintese de peptidos em solucao

Country Status (25)

Country Link
US (4) US20030018164A1 (enExample)
EP (1) EP1291356B1 (enExample)
JP (1) JP4142907B2 (enExample)
KR (1) KR100861031B1 (enExample)
CN (1) CN1254483C (enExample)
AR (1) AR034869A1 (enExample)
AT (1) ATE302792T1 (enExample)
BR (1) BRPI0202783B1 (enExample)
CA (1) CA2390358C (enExample)
DE (1) DE60205693T2 (enExample)
DK (1) DK1291356T3 (enExample)
EC (1) ECSP024291A (enExample)
ES (1) ES2248485T3 (enExample)
HR (1) HRP20020609B1 (enExample)
HU (1) HUP0202369A2 (enExample)
IL (1) IL150601A (enExample)
MX (1) MXPA02006998A (enExample)
NO (1) NO324245B1 (enExample)
PE (1) PE20030214A1 (enExample)
PL (1) PL205559B1 (enExample)
PT (1) PT1291356E (enExample)
RU (1) RU2237673C2 (enExample)
SG (1) SG119160A1 (enExample)
TW (1) TWI247012B (enExample)
ZA (1) ZA200205409B (enExample)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
TWI247012B (en) * 2001-07-19 2006-01-11 Akzo Nobel Nv Process for rapid solution synthesis of peptides
EP1801086A1 (en) * 2005-11-25 2007-06-27 Synthacon GmbH Synthesis of carbon acid amides
EP1790656A1 (en) * 2005-11-25 2007-05-30 Nanokem S.A. Solution-phase synthesis of leuprolide
BRPI0706400A2 (pt) * 2006-01-17 2011-03-29 Organon Nv processos para a hidrólise enzimática seletiva de terc-butil ésteres c-terminais de substratos de peptìdeo, para a sìntese convergente de um peptìdeo de dois ou mais fragmentos de peptìdeo, para a sìntese enzimática por etapas de um peptìdeo na direção do terminal c, e para a sìntese de peptìdeo
ES2729197T3 (es) * 2006-03-01 2019-10-30 Kaneka Corp Método de producción de péptidos
US8124372B2 (en) 2007-06-25 2012-02-28 N.V. Organon Selective enzymatic amidation of C-terminal esters or acids of peptides
MX2009013623A (es) * 2007-06-25 2010-01-20 Organon Nv Proceso para la conversion de esteres o acidos de peptido de terminal c, a amidas que emplean subtilisina en la presencia de sales de amonio.
RU2482127C2 (ru) * 2008-12-30 2013-05-20 Гкл-Биотек Аг Комбинация пептидов
KR101032399B1 (ko) * 2010-02-11 2011-05-03 주식회사 이너트론 밴드패스필터의 철재하우징 및 그 제조방법
EP2409982A3 (en) * 2010-02-25 2012-02-08 Corning Incorporated Chemical processes generating solid(s) carried out continuously within microreactors
JP6136934B2 (ja) 2011-12-15 2017-05-31 味の素株式会社 Ｆｍｏｃ基の除去方法
CN107406480B (zh) 2015-03-04 2022-06-24 Jitsubo株式会社 肽合成方法
CN108697770B (zh) 2015-12-21 2023-08-01 得克萨斯技术大学联合体 用于溶液相gap肽合成的系统和方法
JP6703668B2 (ja) 2018-04-13 2020-06-03 Jitsubo株式会社 ペプチド合成方法
US12024537B2 (en) 2018-05-31 2024-07-02 Sederma Compositions and methods for chemical synthesis
WO2020159837A1 (en) 2019-02-01 2020-08-06 Gap Peptides Llc Synthesis strategy for gap protecting group
FR3090636B1 (fr) * 2018-12-24 2021-01-01 Strainchem Procédé de synthèse de peptides
US12466850B2 (en) * 2019-08-30 2025-11-11 Nissan Chemical Corporation Method for producing peptide compound
EP4083051A4 (en) 2019-12-27 2024-01-17 Chugai Seiyaku Kabushiki Kaisha METHOD FOR SYNTHESIS OF A PEPTIDE COMPOUND
JP7659541B2 (ja) * 2020-03-27 2025-04-09 株式会社カネカ アミド結合含有化合物の製造方法
JP7165289B1 (ja) * 2021-05-07 2022-11-02 中外製薬株式会社 Ｎ－置換アミノ酸残基を含む環状化合物の製造方法
JP7063408B1 (ja) 2021-07-02 2022-05-09 ペプチスター株式会社 液相ペプチド製造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1991A (en) * 1841-02-23 Manner of fastening bedsteads
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis
US5101059A (en) * 1989-12-05 1992-03-31 Research Corporation Technologies, Inc. Amino acid protecting groups
US5877278A (en) * 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US5516892A (en) * 1992-12-28 1996-05-14 Indiana University Foundation Polymer-bound mixed carboxylic anhdrides as a stable form of activated carboxylic acids
US6310180B1 (en) * 1993-06-21 2001-10-30 Vanderbilt University Method for synthesis of proteins
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US6001966A (en) * 1995-10-19 1999-12-14 Proligo Llc Method for solution phase synthesis of oligonucleotides and peptides
US5698676A (en) * 1995-11-30 1997-12-16 Abbott Laboratories Use of propylene oxide as an acid scavenger in peptide synthesis
US5849954A (en) * 1996-01-18 1998-12-15 Research Corporation Technologies, Inc. Method of peptide synthesis
WO1997042230A1 (en) * 1996-05-03 1997-11-13 Warner-Lambert Company Rapid purification by polymer supported quench
US6121488A (en) * 1997-09-24 2000-09-19 Warner-Lambert Company Quenching reagents for solution phase synthesis
JPH11217397A (ja) * 1997-11-27 1999-08-10 Saburo Aimoto ペプチドチオールエステルの製造方法
FR2780061B1 (fr) * 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
JP2003500415A (ja) * 1999-05-26 2003-01-07 アボット・ラボラトリーズ イオン交換樹脂をスカベンジャーとして使用して単離処理を最も少なくしたペプチド合成方法
US20020127219A1 (en) * 1999-12-30 2002-09-12 Okkels Jens Sigurd Lysosomal enzymes and lysosomal enzyme activators
CA2410898A1 (en) * 2000-07-19 2002-01-24 Pharmacia & Upjohn Company Substrates and assays for .beta.-secretase activity
TWI247012B (en) * 2001-07-19 2006-01-11 Akzo Nobel Nv Process for rapid solution synthesis of peptides
TWI243826B (en) * 2001-07-19 2005-11-21 Akzo Nobel Nv Process for the preparation of peptides
US7510768B2 (en) * 2005-06-17 2009-03-31 Eastman Chemical Company Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein

Also Published As

Publication number Publication date
NO20023446D0 (no) 2002-07-18
BR0202783A (pt) 2003-06-10
US20040082760A1 (en) 2004-04-29
AR034869A1 (es) 2004-03-24
NO324245B1 (no) 2007-09-17
CA2390358C (en) 2004-12-21
ECSP024291A (es) 2002-09-27
EP1291356A3 (en) 2004-01-02
PE20030214A1 (es) 2003-03-17
HU0202369D0 (enExample) 2002-09-28
EP1291356B1 (en) 2005-08-24
US20060063918A1 (en) 2006-03-23
KR100861031B1 (ko) 2008-10-01
CN1398876A (zh) 2003-02-26
HUP0202369A2 (en) 2006-08-28
DE60205693T2 (de) 2006-06-14
DK1291356T3 (da) 2005-12-19
EP1291356A2 (en) 2003-03-12
PL205559B1 (pl) 2010-05-31
RU2002119630A (ru) 2004-01-20
US20030018164A1 (en) 2003-01-23
JP4142907B2 (ja) 2008-09-03
CN1254483C (zh) 2006-05-03
ZA200205409B (en) 2002-09-05
DE60205693D1 (de) 2005-09-29
IL150601A (en) 2010-06-30
CA2390358A1 (en) 2003-01-19
ATE302792T1 (de) 2005-09-15
RU2237673C2 (ru) 2004-10-10
HK1050904A1 (en) 2003-07-11
US7435791B2 (en) 2008-10-14
NO20023446L (no) 2003-01-20
MXPA02006998A (es) 2005-02-17
US20040087768A1 (en) 2004-05-06
SG119160A1 (en) 2006-02-28
BRPI0202783B1 (pt) 2016-07-05
IL150601A0 (en) 2003-02-12
TWI247012B (en) 2006-01-11
HRP20020609A2 (en) 2003-02-28
ES2248485T3 (es) 2006-03-16
PL355125A1 (en) 2003-01-27
HRP20020609B1 (en) 2005-06-30
KR20030009188A (ko) 2003-01-29
JP2003055396A (ja) 2003-02-26

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