ATE302792T1 - Verfahren zur schnellen synthese von peptiden in lösung - Google Patents

Verfahren zur schnellen synthese von peptiden in lösung

Info

Publication number
ATE302792T1
ATE302792T1 AT02077830T AT02077830T ATE302792T1 AT E302792 T1 ATE302792 T1 AT E302792T1 AT 02077830 T AT02077830 T AT 02077830T AT 02077830 T AT02077830 T AT 02077830T AT E302792 T1 ATE302792 T1 AT E302792T1
Authority
AT
Austria
Prior art keywords
peptides
solution
rapid synthesis
synthesis
rapid
Prior art date
Application number
AT02077830T
Other languages
German (de)
English (en)
Inventor
Ivo Franci Eggen
Kortenaar Paulus Bernardus Ten
Cornelis Albert Gruso Haasnoot
Original Assignee
Akzo Nobel Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Akzo Nobel Nv filed Critical Akzo Nobel Nv
Application granted granted Critical
Publication of ATE302792T1 publication Critical patent/ATE302792T1/de

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K1/00General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/02General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length in solution

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
AT02077830T 2001-07-19 2002-07-15 Verfahren zur schnellen synthese von peptiden in lösung ATE302792T1 (de)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
EP01202753 2001-07-19

Publications (1)

Publication Number Publication Date
ATE302792T1 true ATE302792T1 (de) 2005-09-15

Family

ID=8180656

Family Applications (1)

Application Number Title Priority Date Filing Date
AT02077830T ATE302792T1 (de) 2001-07-19 2002-07-15 Verfahren zur schnellen synthese von peptiden in lösung

Country Status (25)

Country Link
US (4) US20030018164A1 (enExample)
EP (1) EP1291356B1 (enExample)
JP (1) JP4142907B2 (enExample)
KR (1) KR100861031B1 (enExample)
CN (1) CN1254483C (enExample)
AR (1) AR034869A1 (enExample)
AT (1) ATE302792T1 (enExample)
BR (1) BRPI0202783B1 (enExample)
CA (1) CA2390358C (enExample)
DE (1) DE60205693T2 (enExample)
DK (1) DK1291356T3 (enExample)
EC (1) ECSP024291A (enExample)
ES (1) ES2248485T3 (enExample)
HR (1) HRP20020609B1 (enExample)
HU (1) HUP0202369A2 (enExample)
IL (1) IL150601A (enExample)
MX (1) MXPA02006998A (enExample)
NO (1) NO324245B1 (enExample)
PE (1) PE20030214A1 (enExample)
PL (1) PL205559B1 (enExample)
PT (1) PT1291356E (enExample)
RU (1) RU2237673C2 (enExample)
SG (1) SG119160A1 (enExample)
TW (1) TWI247012B (enExample)
ZA (1) ZA200205409B (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL150601A (en) * 2001-07-19 2010-06-30 Organon Nv Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component
EP1790656A1 (en) 2005-11-25 2007-05-30 Nanokem S.A. Solution-phase synthesis of leuprolide
EP1801086A1 (en) * 2005-11-25 2007-06-27 Synthacon GmbH Synthesis of carbon acid amides
US20090093016A1 (en) * 2006-01-17 2009-04-09 N.V. Organon Selective Enzymatic Hydrolysis of C-Terminal Tert-Butyl Esters of Peptides
US8716439B2 (en) 2006-03-01 2014-05-06 Kaneka Corporation Method of producing peptide
US8124372B2 (en) 2007-06-25 2012-02-28 N.V. Organon Selective enzymatic amidation of C-terminal esters or acids of peptides
DE602008004350D1 (de) * 2007-06-25 2011-02-17 Organon Nv Verfahren zur umsetzung von c-terminalen peptidestern oder -säuren zu amiden unter verwendung von subtilisin in gegenwart von ammoniumsalzen
RU2482127C2 (ru) * 2008-12-30 2013-05-20 Гкл-Биотек Аг Комбинация пептидов
KR101032399B1 (ko) * 2010-02-11 2011-05-03 주식회사 이너트론 밴드패스필터의 철재하우징 및 그 제조방법
EP2409982A3 (en) * 2010-02-25 2012-02-08 Corning Incorporated Chemical processes generating solid(s) carried out continuously within microreactors
WO2013089241A1 (ja) 2011-12-15 2013-06-20 味の素株式会社 Fmoc基の除去方法
CN107406480B (zh) 2015-03-04 2022-06-24 Jitsubo株式会社 肽合成方法
CA3009065C (en) 2015-12-21 2022-01-25 Texas Tech University System System and method for solution phase gap peptide synthesis
CN111971293B (zh) 2018-04-13 2024-07-30 Jitsubo株式会社 肽合成方法
US12024537B2 (en) 2018-05-31 2024-07-02 Sederma Compositions and methods for chemical synthesis
FR3090636B1 (fr) * 2018-12-24 2021-01-01 Strainchem Procédé de synthèse de peptides
CA3126705A1 (en) 2019-02-01 2020-08-06 Gap Peptides Llc Synthesis strategy for gap protecting group
EP4023661B1 (en) * 2019-08-30 2024-09-04 Nissan Chemical Corporation Method for producing peptide compound
WO2021132545A1 (ja) * 2019-12-27 2021-07-01 中外製薬株式会社 ペプチド化合物の合成法
WO2021192488A1 (ja) * 2020-03-27 2021-09-30 株式会社カネカ アミド結合含有化合物の製造方法
JP7063408B1 (ja) 2021-07-02 2022-05-09 ペプチスター株式会社 液相ペプチド製造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1991A (en) * 1841-02-23 Manner of fastening bedsteads
US5221754A (en) * 1989-06-09 1993-06-22 Research Corporation Technologies, Inc. Reagents for rapid peptide synthesis
US5101059A (en) * 1989-12-05 1992-03-31 Research Corporation Technologies, Inc. Amino acid protecting groups
US5877278A (en) 1992-09-24 1999-03-02 Chiron Corporation Synthesis of N-substituted oligomers
US5516892A (en) 1992-12-28 1996-05-14 Indiana University Foundation Polymer-bound mixed carboxylic anhdrides as a stable form of activated carboxylic acids
US6310180B1 (en) * 1993-06-21 2001-10-30 Vanderbilt University Method for synthesis of proteins
US5516639A (en) * 1993-07-22 1996-05-14 Mayo Foundation For Medical Education And Research Antibodies specific for human prostate glandular kallkrein
US6001966A (en) * 1995-10-19 1999-12-14 Proligo Llc Method for solution phase synthesis of oligonucleotides and peptides
US5698676A (en) * 1995-11-30 1997-12-16 Abbott Laboratories Use of propylene oxide as an acid scavenger in peptide synthesis
US5849954A (en) * 1996-01-18 1998-12-15 Research Corporation Technologies, Inc. Method of peptide synthesis
US6306959B1 (en) 1996-05-03 2001-10-23 Warner Lambert Company Rapid purification by polymer supported quench
US6121488A (en) * 1997-09-24 2000-09-19 Warner-Lambert Company Quenching reagents for solution phase synthesis
JPH11217397A (ja) * 1997-11-27 1999-08-10 Saburo Aimoto ペプチドチオールエステルの製造方法
FR2780061B1 (fr) 1998-06-22 2001-09-07 Rhone Poulenc Rorer Sa Nouveau procede de preparation de derives de cyclosporine
WO2000071569A1 (en) * 1999-05-26 2000-11-30 Abbott Laboratories Minimal isolation peptide synthesis process using ion-exchange resins as scavenging agents
US20020127219A1 (en) 1999-12-30 2002-09-12 Okkels Jens Sigurd Lysosomal enzymes and lysosomal enzyme activators
WO2002006306A2 (en) 2000-07-19 2002-01-24 Pharmacia & Upjohn Company SUBSTRATES AND ASSAYS FOR β-SECRETASE ACTIVITY
TWI243826B (en) * 2001-07-19 2005-11-21 Akzo Nobel Nv Process for the preparation of peptides
IL150601A (en) * 2001-07-19 2010-06-30 Organon Nv Process for rapid synthesis of peptides within a solution using the back of an activated carboxyl component and destruction of the residual activated carboxyl component
US7510768B2 (en) * 2005-06-17 2009-03-31 Eastman Chemical Company Thermoplastic articles comprising cyclobutanediol having a decorative material embedded therein

Also Published As

Publication number Publication date
US20040087768A1 (en) 2004-05-06
DE60205693T2 (de) 2006-06-14
ZA200205409B (en) 2002-09-05
EP1291356A3 (en) 2004-01-02
CA2390358C (en) 2004-12-21
PL355125A1 (en) 2003-01-27
SG119160A1 (en) 2006-02-28
EP1291356A2 (en) 2003-03-12
ES2248485T3 (es) 2006-03-16
BR0202783A (pt) 2003-06-10
MXPA02006998A (es) 2005-02-17
CN1254483C (zh) 2006-05-03
HU0202369D0 (enExample) 2002-09-28
PT1291356E (pt) 2005-11-30
HUP0202369A2 (en) 2006-08-28
KR100861031B1 (ko) 2008-10-01
DE60205693D1 (de) 2005-09-29
US7435791B2 (en) 2008-10-14
HK1050904A1 (en) 2003-07-11
NO324245B1 (no) 2007-09-17
DK1291356T3 (da) 2005-12-19
HRP20020609B1 (en) 2005-06-30
US20030018164A1 (en) 2003-01-23
AR034869A1 (es) 2004-03-24
TWI247012B (en) 2006-01-11
CA2390358A1 (en) 2003-01-19
US20060063918A1 (en) 2006-03-23
RU2002119630A (ru) 2004-01-20
NO20023446D0 (no) 2002-07-18
ECSP024291A (es) 2002-09-27
PE20030214A1 (es) 2003-03-17
IL150601A0 (en) 2003-02-12
KR20030009188A (ko) 2003-01-29
CN1398876A (zh) 2003-02-26
JP4142907B2 (ja) 2008-09-03
US20040082760A1 (en) 2004-04-29
RU2237673C2 (ru) 2004-10-10
IL150601A (en) 2010-06-30
NO20023446L (no) 2003-01-20
JP2003055396A (ja) 2003-02-26
BRPI0202783B1 (pt) 2016-07-05
EP1291356B1 (en) 2005-08-24
HRP20020609A2 (en) 2003-02-28
PL205559B1 (pl) 2010-05-31

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