US6136311A
(en)
|
1996-05-06 |
2000-10-24 |
Cornell Research Foundation, Inc. |
Treatment and diagnosis of cancer
|
US7754208B2
(en)
|
2001-01-17 |
2010-07-13 |
Trubion Pharmaceuticals, Inc. |
Binding domain-immunoglobulin fusion proteins
|
DE10254601A1
(de)
|
2002-11-22 |
2004-06-03 |
Ganymed Pharmaceuticals Ag |
Differentiell in Tumoren exprimierte Genprodukte und deren Verwendung
|
CN101282745B
(zh)
|
2005-07-25 |
2015-04-29 |
新兴产品开发西雅图有限公司 |
用cd37-特异性和cd20-特异性结合分子减少b-细胞
|
EP1976886B1
(de)
|
2005-12-16 |
2014-12-17 |
Amgen Research (Munich) GmbH |
Mittel und verfahren zur behandlung von tumorkrankheiten
|
AU2013202375B2
(en)
*
|
2005-12-16 |
2016-10-27 |
Amgen Research (Munich) Gmbh |
Means and Methods for the Treatment of Tumorous Diseases
|
CN101426521A
(zh)
*
|
2005-12-21 |
2009-05-06 |
医疗免疫有限责任公司 |
EPHA2 BiTE分子及其应用
|
JP5399712B2
(ja)
|
2005-12-21 |
2014-01-29 |
アムゲン リサーチ (ミュンヘン) ゲーエムベーハー |
可溶性ceaに対する抵抗性を有する医薬組成物
|
EP1996716B1
(de)
|
2006-03-20 |
2011-05-11 |
The Regents of the University of California |
Manipulierte anti-prostatastammzellenantigen (psca)-antikörper für krebs-targeting
|
MX2008015524A
(es)
|
2006-06-12 |
2009-01-13 |
Trubion Pharmaceuticals Inc |
Proteinas de union multivalentes monocatenarias con funcion efectora.
|
WO2008079466A1
(en)
*
|
2006-12-20 |
2008-07-03 |
Mmr Information Systems, Inc. |
Antibodies and methods for making and using them
|
AU2013202392B2
(en)
*
|
2006-12-20 |
2016-02-25 |
Mmrglobal, Inc. |
Antibodies and methods for making and using them
|
DE202007016718U1
(de)
*
|
2007-02-21 |
2008-04-03 |
K.L. Kaschier- Und Laminier Gmbh |
Airbagdeckelscharnier mit kraftaufnehmendem System
|
US20100183615A1
(en)
*
|
2007-04-03 |
2010-07-22 |
Micromet Ag |
Cross-species-specific bispecific binders
|
TR201816277T4
(tr)
*
|
2007-04-03 |
2018-11-21 |
Amgen Res Munich Gmbh |
Çapraz-tür-spesifik bağlama alanı.
|
US8940298B2
(en)
*
|
2007-09-04 |
2015-01-27 |
The Regents Of The University Of California |
High affinity anti-prostate stem cell antigen (PSCA) antibodies for cancer targeting and detection
|
US20100291113A1
(en)
*
|
2007-10-03 |
2010-11-18 |
Cornell University |
Treatment of Proliferative Disorders Using Antibodies to PSMA
|
SI2132228T1
(sl)
|
2008-04-11 |
2011-10-28 |
Emergent Product Dev Seatle |
CD37 imunoterapevtik in kombinacija z njegovim bifunkcionalnim kemoterapevtikom
|
US20100069616A1
(en)
*
|
2008-08-06 |
2010-03-18 |
The Regents Of The University Of California |
Engineered antibody-nanoparticle conjugates
|
WO2010037835A2
(en)
|
2008-10-01 |
2010-04-08 |
Micromet Ag |
Cross-species-specific pscaxcd3, cd19xcd3, c-metxcd3, endosialinxcd3, epcamxc d3, igf-1rxcd3 or fapalpha xcd3 bispecific single chain antibody
|
CA2738565C
(en)
|
2008-10-01 |
2023-10-10 |
Micromet Ag |
Cross-species-specific psmaxcd3 bispecific single chain antibody
|
PT2352763E
(pt)
|
2008-10-01 |
2016-06-02 |
Amgen Res (Munich) Gmbh |
Anticorpos biespecíficos de cadeia única com especificidade para antigénios-alvo com elevado peso molecular
|
PL2344539T3
(pl)
*
|
2008-11-07 |
2015-07-31 |
Amgen Res Munich Gmbh |
Leczenie pediatrycznej ostrej białaczki limfoblastycznej
|
SI2982696T1
(sl)
*
|
2008-11-07 |
2019-06-28 |
Amgen Research (Munich) Gmbh |
Zdravljenje akutne limfoblastne levkemije
|
ES2712732T3
(es)
*
|
2009-02-17 |
2019-05-14 |
Cornell Res Foundation Inc |
Métodos y kits para el diagnóstico de cáncer y la predicción de valor terapéutico
|
SG179027A1
(en)
|
2009-09-18 |
2012-04-27 |
Micromet Ag |
Dosage regimen for administering an epcamxcd3 bispecific antibody
|
CN102753194B
(zh)
|
2009-12-02 |
2015-07-08 |
伊麦吉纳博公司 |
靶向人前列腺特异性膜抗原的j591微抗体和双抗体
|
TWI653333B
(zh)
*
|
2010-04-01 |
2019-03-11 |
安進研究(慕尼黑)有限責任公司 |
跨物種專一性之PSMAxCD3雙專一性單鏈抗體
|
SG189929A1
(en)
*
|
2010-10-29 |
2013-06-28 |
Immunogen Inc |
Novel egfr-binding molecules and immunoconjugates thereof
|
WO2012066058A1
(en)
|
2010-11-16 |
2012-05-24 |
Boehringer Ingelheim International Gmbh |
Agents and methods for treating diseases that correlate with bcma expression
|
US9249217B2
(en)
|
2010-12-03 |
2016-02-02 |
Secretary, DHHS |
Bispecific EGFRvIII x CD3 antibody engaging molecules
|
US10239952B2
(en)
*
|
2011-04-01 |
2019-03-26 |
Memorial Sloan Kettering Cancer Center |
Anti-WT1/HLA bi-specific antibody
|
JP2014518615A
(ja)
|
2011-04-22 |
2014-08-07 |
エマージェント プロダクト デベロップメント シアトル, エルエルシー |
前立腺特異的膜抗原結合タンパク質および関連組成物ならびに方法
|
DE102011118022B4
(de)
*
|
2011-06-30 |
2018-01-18 |
Gemoab Monoclonals Gmbh |
Antikörper gegen das Prostata-spezifische Stammzellenantigen und dessen Verwendung
|
CN102337298B
(zh)
*
|
2011-08-19 |
2013-11-06 |
黄开红 |
一种输送siRNA的免疫纳米载体及其制备方法和应用
|
EP2747781B1
(de)
|
2011-08-23 |
2017-11-15 |
Roche Glycart AG |
Bispezifische antikörper spezifisch für t-zell-aktivierende antigene und ein tumorantigen sowie verwendungsverfahren
|
TWI679212B
(zh)
|
2011-11-15 |
2019-12-11 |
美商安進股份有限公司 |
針對bcma之e3以及cd3的結合分子
|
AU2012350429A1
(en)
|
2011-12-09 |
2013-07-11 |
Amgen Research (Munich) Gmbh |
Prevention of adverse effects caused by EpCAMxCD3 bispecific antibodies
|
CN108034006A
(zh)
*
|
2012-01-13 |
2018-05-15 |
乌利班-马克西姆利安大学 |
双抗原诱导的双功能互补作用
|
GB201203442D0
(en)
|
2012-02-28 |
2012-04-11 |
Univ Birmingham |
Immunotherapeutic molecules and uses
|
ES2680151T3
(es)
|
2012-03-01 |
2018-09-04 |
Amgen Research (Munich) Gmbh |
Moléculas de unión de polipéptidos de larga duración
|
CA2876133C
(en)
*
|
2012-06-07 |
2017-06-06 |
Duke University |
Human bispecific egfrviii antibody engaging molecules
|
WO2014004549A2
(en)
|
2012-06-27 |
2014-01-03 |
Amgen Inc. |
Anti-mesothelin binding proteins
|
WO2014028560A2
(en)
|
2012-08-14 |
2014-02-20 |
Ibc Pharmaceuticals, Inc. |
T-cell redirecting bispecific antibodies for treatment of disease
|
US20150231241A1
(en)
*
|
2012-08-14 |
2015-08-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
US9682143B2
(en)
|
2012-08-14 |
2017-06-20 |
Ibc Pharmaceuticals, Inc. |
Combination therapy for inducing immune response to disease
|
AU2013306390B2
(en)
|
2012-08-24 |
2018-07-05 |
The Regents Of The University Of California |
Antibodies and vaccines for use in treating ROR1 cancers and inhibiting metastasis
|
JOP20200236A1
(ar)
*
|
2012-09-21 |
2017-06-16 |
Regeneron Pharma |
الأجسام المضادة لمضاد cd3 وجزيئات ربط الأنتيجين ثنائية التحديد التي تربط cd3 وcd20 واستخداماتها
|
JP6499079B2
(ja)
|
2012-11-13 |
2019-04-10 |
バイオエヌテック アーゲーBioNTech AG |
クローディンを発現するガン疾患を処置するための剤
|
ES2681948T3
(es)
*
|
2013-03-05 |
2018-09-17 |
Baylor College Of Medicine |
Células de acoplamiento para inmunoterapia
|
KR20210054067A
(ko)
|
2013-06-14 |
2021-05-12 |
싸이오서스 테라퓨틱스 엘티디. |
유형 b 아데노바이러스에 대한 투여 요법 및 제형
|
CN105722859B
(zh)
|
2013-07-25 |
2021-05-07 |
西托姆克斯治疗公司 |
多特异性抗体、多特异性可活化抗体及其使用方法
|
CN104342453A
(zh)
*
|
2013-08-06 |
2015-02-11 |
深圳先进技术研究院 |
含基因工程抗体基因表达盒的微环dna重组母质粒、含该表达盒的微环dna及应用
|
CA3178299A1
(en)
|
2013-10-11 |
2015-04-16 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Tem8 antibodies and their use
|
WO2015059303A1
(en)
|
2013-10-25 |
2015-04-30 |
Psioxus Therapeutics Limited |
Oncolytic adenoviruses armed with heterologous genes
|
CN106414500B
(zh)
*
|
2013-11-07 |
2020-04-10 |
纪念斯隆-凯特琳癌症中心 |
抗-wt1/hla双特异性抗体
|
WO2015103549A1
(en)
|
2014-01-03 |
2015-07-09 |
The United States Of America, As Represented By The Secretary Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
EP3102681B1
(de)
|
2014-02-07 |
2023-10-04 |
McMaster University |
Trifunktionaler t-zell-antigenkoppler sowie verfahren und verwendungen davon
|
TWI701042B
(zh)
|
2014-03-19 |
2020-08-11 |
美商再生元醫藥公司 |
用於腫瘤治療之方法及抗體組成物
|
WO2015144852A1
(en)
*
|
2014-03-26 |
2015-10-01 |
Delenex Therapeutics Ag |
Binding members to tnf alpha
|
IL278350B
(en)
|
2014-04-03 |
2022-06-01 |
Igm Biosciences Inc |
J-chain qualified
|
EP2930188A1
(de)
*
|
2014-04-13 |
2015-10-14 |
Affimed Therapeutics AG |
Trifunktionelles Antigen-bindendes Molekül
|
US9212225B1
(en)
|
2014-07-01 |
2015-12-15 |
Amphivena Therapeutics, Inc. |
Bispecific CD33 and CD3 binding proteins
|
BR112017001579A2
(pt)
|
2014-07-25 |
2017-11-21 |
Cytomx Therapeutics Inc |
anticorpos anti-cd3, anticorpos anti-cd3 ativáveis, anticorpos anti-cd3 multiespecíficos, anticorpos anti-cd3 ativáveis multiespecíficos e métodos de uso dos mesmos
|
TW201609812A
(zh)
|
2014-07-31 |
2016-03-16 |
安美基研究(慕尼黑)公司 |
最佳化之跨物種特異性雙特異性單鏈抗體構築體
|
EP3875481A1
(de)
|
2014-11-14 |
2021-09-08 |
The U.S.A. as represented by the Secretary, Department of Health and Human Services |
Neutralisierende antikörper gegen ebola-virus-glycoprotein und deren verwendung
|
MX2017006312A
(es)
|
2014-11-17 |
2017-08-21 |
Regeneron Pharma |
Metodos para el tratamiento tumoral utilizando el anticuerpo biespecifico cd3xcd20.
|
NZ732073A
(en)
*
|
2014-12-08 |
2019-04-26 |
1Globe Biomedical Co Ltd |
Soluble universal adcc-enhancing synthetic fusion gene and peptide technology and its use thereof
|
EP3261665A1
(de)
|
2015-02-24 |
2018-01-03 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Mers-coronavirusimmunogene, antikörper und deren verwendung
|
ES2874558T3
(es)
|
2015-03-04 |
2021-11-05 |
Igm Biosciences Inc |
Moléculas de unión a CD20 y usos de las mismas
|
CA2980005A1
(en)
|
2015-03-20 |
2016-09-29 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to gp120 and their use
|
TW202311292A
(zh)
|
2015-04-17 |
2023-03-16 |
德商安美基研究(慕尼黑)公司 |
Cdh3與cd3之雙特異性抗體構築體
|
EP3466967A1
(de)
|
2015-05-18 |
2019-04-10 |
TCR2 Therapeutics Inc. |
Zusammensetzungen und verfahren für tcr-programmierung mit fusionsproteinen
|
EA201792581A1
(ru)
|
2015-05-29 |
2018-07-31 |
Амфивена Терапьютикс, Инк. |
Способы применения биспецифических cd33- и cd3- связывающих белков
|
TWI796283B
(zh)
|
2015-07-31 |
2023-03-21 |
德商安美基研究(慕尼黑)公司 |
Msln及cd3抗體構築體
|
TWI744242B
(zh)
|
2015-07-31 |
2021-11-01 |
德商安美基研究(慕尼黑)公司 |
Egfrviii及cd3抗體構築體
|
TW202346349A
(zh)
|
2015-07-31 |
2023-12-01 |
德商安美基研究(慕尼黑)公司 |
Dll3及cd3抗體構築體
|
TWI717375B
(zh)
|
2015-07-31 |
2021-02-01 |
德商安美基研究(慕尼黑)公司 |
Cd70及cd3抗體構築體
|
TWI829617B
(zh)
|
2015-07-31 |
2024-01-21 |
德商安美基研究(慕尼黑)公司 |
Flt3及cd3抗體構築體
|
JO3620B1
(ar)
|
2015-08-05 |
2020-08-27 |
Amgen Res Munich Gmbh |
مثبطات نقطة فحص مناعية للاستخدام في علاج سرطانات محمولة عبر الدم
|
US11254744B2
(en)
|
2015-08-07 |
2022-02-22 |
Imaginab, Inc. |
Antigen binding constructs to target molecules
|
US11713358B2
(en)
|
2015-08-28 |
2023-08-01 |
Amunix Pharmaceuticals, Inc. |
Chimeric polypeptide assembly and methods of making and using the same
|
UA126278C2
(uk)
|
2015-09-21 |
2022-09-14 |
Аптево Рісьорч Енд Девелопмент Ллс |
Поліпептиди, які зв'язують cd3
|
EP3356401B1
(de)
*
|
2015-09-30 |
2020-06-24 |
IGM Biosciences, Inc. |
Bindungsmoleküle mit modifizierter j-kette
|
EP3355913A1
(de)
|
2015-09-30 |
2018-08-08 |
IGM Biosciences A/S |
Bindungsmoleküle mit modifizierter j-kette
|
WO2017062748A1
(en)
|
2015-10-07 |
2017-04-13 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Il-7r-alpha specific antibodies for treating acute lymphoblastic leukemia
|
WO2017070943A1
(zh)
*
|
2015-10-30 |
2017-05-04 |
江苏众红生物工程创药研究院有限公司 |
双特异性抗体、其制备方法和用途
|
EP4011911A1
(de)
|
2015-11-03 |
2022-06-15 |
The United States of America as represented by The Secretary Department of Health and Human Services |
Neutralisierende antikörper gegen hiv-1 gp41 und deren verwendung
|
EP3377103B1
(de)
|
2015-11-19 |
2021-03-17 |
Revitope Limited |
Komplementierung eines funktionellen antikörperfragments für ein zwei-komponenten-system zur umgelenkten tötung unerwünschter zellen
|
WO2017097723A2
(en)
|
2015-12-09 |
2017-06-15 |
F. Hoffmann-La Roche Ag |
Treatment method
|
KR20180108590A
(ko)
|
2015-12-17 |
2018-10-04 |
싸이오서스 테라퓨틱스 엘티디. |
항-tcr-복합체 항체 또는 단편을 암호화하는 바이러스
|
JOP20170017B1
(ar)
|
2016-01-25 |
2021-08-17 |
Amgen Res Munich Gmbh |
تركيب صيدلي يتضمن تركيبات جسم مضاد ثنائي الاختصاص
|
EP3411404B1
(de)
|
2016-02-03 |
2022-11-09 |
Amgen Research (Munich) GmbH |
Psma- und cd3-bispezifische t-zellaktivierende antikörperkonstrukte
|
EA039859B1
(ru)
|
2016-02-03 |
2022-03-21 |
Эмджен Рисерч (Мюник) Гмбх |
Биспецифические конструкты антител, связывающие egfrviii и cd3
|
DK3411402T3
(da)
|
2016-02-03 |
2022-02-07 |
Amgen Res Munich Gmbh |
Bcma- og cd3-bispecifikke t-celle-engagerende antistofkonstruktioner
|
SG11201807548SA
(en)
*
|
2016-03-08 |
2018-09-27 |
Maverick Therapeutics Inc |
Inducible binding proteins and methods of use
|
WO2017167350A1
(en)
*
|
2016-03-30 |
2017-10-05 |
Horst Lindhofer |
Multispecific antibodies for use in the treatment of a neoplasm of the urinary tract
|
JOP20170091B1
(ar)
|
2016-04-19 |
2021-08-17 |
Amgen Res Munich Gmbh |
إعطاء تركيبة ثنائية النوعية ترتبط بـ cd33 وcd3 للاستخدام في طريقة لعلاج اللوكيميا النخاعية
|
WO2017192589A1
(en)
|
2016-05-02 |
2017-11-09 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to influenza ha and their use and identification
|
EP3252078A1
(de)
|
2016-06-02 |
2017-12-06 |
F. Hoffmann-La Roche AG |
Typ ii anti-cd20 antikörper und anti-cd20/cd3 bispecific antikörper zur behandlung von krebs
|
KR20190053835A
(ko)
|
2016-06-21 |
2019-05-20 |
테네오바이오, 인코포레이티드 |
Cd3 결합 항체
|
KR20190022752A
(ko)
|
2016-06-27 |
2019-03-06 |
더 리젠츠 오브 더 유니버시티 오브 캘리포니아 |
암 치료 조합
|
BR112019000166A2
(pt)
|
2016-07-06 |
2019-10-01 |
Celgene Corp |
anticorpos com baixa imunogenicidade e usos dos mesmos
|
US11242376B2
(en)
|
2016-08-02 |
2022-02-08 |
TCR2 Therapeutics Inc. |
Compositions and methods for TCR reprogramming using fusion proteins
|
IL264902B2
(en)
|
2016-08-29 |
2023-11-01 |
Akamis Bio Ltd |
Adenovirus with bispecific T cell activator
|
GB201713765D0
(en)
|
2017-08-28 |
2017-10-11 |
Psioxus Therapeutics Ltd |
Modified adenovirus
|
KR20230035706A
(ko)
|
2016-09-14 |
2023-03-14 |
테네오원, 인코포레이티드 |
Cd3 결합 항체
|
ES2875959T3
(es)
|
2016-10-07 |
2021-11-11 |
Tcr2 Therapeutics Inc |
Composiciones y métodos para reprogramación de receptores de linfocitos T mediante el uso de proteínas de fusión
|
CA3044593A1
(en)
|
2016-11-22 |
2018-05-31 |
TCR2 Therapeutics Inc. |
Compositions and methods for tcr reprogramming using fusion proteins
|
KR20230052309A
(ko)
|
2016-12-21 |
2023-04-19 |
테네오바이오, 인코포레이티드 |
항-bcma 중쇄-단독 항체
|
JOP20190189A1
(ar)
|
2017-02-02 |
2019-08-01 |
Amgen Res Munich Gmbh |
تركيبة صيدلانية ذات درجة حموضة منخفضة تتضمن بنيات جسم مضاد يستهدف الخلية t
|
CN108395482B
(zh)
|
2017-02-08 |
2021-02-05 |
西比曼生物科技(香港)有限公司 |
一种靶向cd20抗原嵌合抗原受体的构建及其工程化t细胞的活性鉴定
|
AU2018219887A1
(en)
|
2017-02-08 |
2019-08-22 |
Dragonfly Therapeutics, Inc. |
Multi-specific binding proteins for activation of natural killer cells and therapeutic uses thereof to treat cancer
|
US11266745B2
(en)
|
2017-02-08 |
2022-03-08 |
Imaginab, Inc. |
Extension sequences for diabodies
|
US11021535B2
(en)
|
2017-02-10 |
2021-06-01 |
The United States Of America As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
CA3235295A1
(en)
|
2017-02-20 |
2018-08-23 |
Dragonfly Therapeutics, Inc. |
Proteins binding her2, nkg2d and cd16
|
CN108690138A
(zh)
*
|
2017-04-12 |
2018-10-23 |
鸿运华宁(杭州)生物医药有限公司 |
一种能与人cd19或cd20和人cd3结合的双特异性抗体及其应用
|
KR20190141243A
(ko)
|
2017-05-05 |
2019-12-23 |
암젠 인크 |
개선된 저장 및 투여를 위한 이중특이적 항체 구축물을 포함하는 약제학적 조성물
|
EP3409322A1
(de)
|
2017-06-01 |
2018-12-05 |
F. Hoffmann-La Roche AG |
Behandlungsverfahren
|
JP2020521791A
(ja)
|
2017-06-02 |
2020-07-27 |
エフ・ホフマン−ラ・ロシュ・アクチェンゲゼルシャフト |
がんの治療のためのii型抗cd20抗体及び抗cd20/cd30二重特異性抗体
|
SG11201912774RA
(en)
|
2017-06-20 |
2020-01-30 |
Teneobio Inc |
Anti-bcma heavy chain-only antibodies
|
GB201710836D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
ROR1 Car T-Cells
|
GB201710835D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
ROR1 Antibodies
|
GB201710838D0
(en)
|
2017-07-05 |
2017-08-16 |
Ucl Business Plc |
Bispecific antibodies
|
JP7079171B2
(ja)
|
2017-08-03 |
2022-06-01 |
アムジエン・インコーポレーテツド |
インターロイキン-21ムテイン及び治療方法
|
MX2020002667A
(es)
|
2017-09-08 |
2020-08-03 |
Maverick Therapeutics Inc |
Proteinas de unión condicionalmente activadas restringidas.
|
CA3075046A1
(en)
|
2017-09-08 |
2019-03-14 |
Amgen Inc. |
Inhibitors of kras g12c and methods of using the same
|
CN107501412A
(zh)
*
|
2017-10-11 |
2017-12-22 |
深圳精准医疗科技有限公司 |
突变型双特异性抗体及其应用
|
CA3078637A1
(en)
|
2017-10-12 |
2019-04-18 |
Mcmaster University |
T cell-antigen coupler with y182t mutation and methods and uses thereof
|
MX2020003856A
(es)
|
2017-10-13 |
2020-08-13 |
Harpoon Therapeutics Inc |
Proteinas de union a antigenos de maduracion de celulas b.
|
GB201717966D0
(en)
*
|
2017-10-31 |
2017-12-13 |
Xenikos Bv |
Immunotoxins, formulations thereof and their use in medicine
|
EP3724229A1
(de)
|
2017-12-11 |
2020-10-21 |
Amgen Inc. |
Kontinuierliches herstellungsverfahren für bispezifische antikörperprodukte
|
TW201940518A
(zh)
|
2017-12-29 |
2019-10-16 |
美商安進公司 |
針對muc17和cd3之雙特異性抗體構建體
|
EP3724223A1
(de)
|
2018-01-02 |
2020-10-21 |
The United States of America, as represented by The Secretary, Department of Health and Human Services |
Neutralisierender antikörper gegen ebola-virus-glycoprotein und deren verwendung
|
JOP20200172A1
(ar)
|
2018-01-12 |
2020-07-12 |
Amgen Inc |
الأجسام المضادة لـ pd-1 وطرق العلاج
|
PE20220278A1
(es)
|
2018-02-08 |
2022-02-25 |
Dragonfly Therapeutics Inc |
Dominios variables de anticuerpos que se dirigen al receptor nkg2d
|
AU2019226034A1
(en)
|
2018-02-21 |
2020-10-15 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to HIV-1 Env and their use
|
CR20200571A
(es)
|
2018-06-01 |
2021-01-18 |
Novartis Ag |
Moléculas de únion contra bcma y usos de las mismas
|
AU2019281019A1
(en)
*
|
2018-06-07 |
2020-11-26 |
Oncoone Research & Development Gmbh |
Anti-oxMIF/anti-CD3 antibody for cancer treatment
|
EP3817770A2
(de)
|
2018-07-02 |
2021-05-12 |
Amgen Inc. |
St2-antigen-bindende proteine
|
US11110123B2
(en)
|
2018-07-17 |
2021-09-07 |
Triumvira Immunologics Usa, Inc. |
T cell-antigen coupler with various construct optimizations
|
US10640562B2
(en)
|
2018-07-17 |
2020-05-05 |
Mcmaster University |
T cell-antigen coupler with various construct optimizations
|
TW202021616A
(zh)
|
2018-07-30 |
2020-06-16 |
美商安進公司 |
結合至cd33和cd3的雙特異性抗體構建體之延長投與
|
EP3830122A1
(de)
|
2018-07-31 |
2021-06-09 |
Amgen Research (Munich) GmbH |
Dosierungsschema für bispezifische bcma-cd3-antikörper
|
AR114541A1
(es)
|
2018-08-03 |
2020-09-16 |
Amgen Res Munich Gmbh |
Constructos de anticuerpos para cldn18.2 y cd3
|
MA53495A
(fr)
|
2018-08-31 |
2021-12-08 |
Regeneron Pharma |
Stratégie de dosage permettant d'atténuer le syndrome de libération de cytokines pour des anticorps bispécifiques cd3/c20
|
CN110872356B
(zh)
*
|
2018-09-03 |
2023-06-13 |
广西慧宝源健康产业有限公司 |
双特异性抗体及其使用方法
|
CA3114038A1
(en)
|
2018-09-25 |
2020-04-02 |
Harpoon Therapeutics, Inc. |
Dll3 binding proteins and methods of use
|
MA53732A
(fr)
|
2018-09-28 |
2022-01-05 |
Amgen Inc |
Anticorps dirigés contre bcma soluble
|
TW202021986A
(zh)
|
2018-10-11 |
2020-06-16 |
美商英伊布里克斯公司 |
5t4單域抗體及其治療性組合物
|
WO2020077257A1
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
Pd-1 single domain antibodies and therapeutic compositions thereof
|
WO2020076977A2
(en)
|
2018-10-11 |
2020-04-16 |
Inhibrx, Inc. |
Dll3 single domain antibodies and therapeutic compositions thereof
|
AU2019356564A1
(en)
|
2018-10-11 |
2021-04-29 |
Amgen Inc. |
Downstream processing of bispecific antibody constructs
|
CN113166261A
(zh)
|
2018-10-11 |
2021-07-23 |
印希比股份有限公司 |
B7h3单域抗体及其治疗性组合物
|
SG11202103232WA
(en)
|
2018-10-23 |
2021-05-28 |
Amgen Inc |
Automatic calibration and automatic maintenance of raman spectroscopic models for real-time predictions
|
BR112021008486A2
(pt)
|
2018-11-01 |
2021-10-26 |
Shandong New Time Pharmaceutical Co., Ltd |
Anticorpo biespecífico e seu uso
|
EP3891181A4
(de)
*
|
2018-12-04 |
2022-08-17 |
Novartis AG |
Bindungsmoleküle gegen cd3 und verwendungen davon
|
EP3883609A2
(de)
|
2018-12-20 |
2021-09-29 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Glykoprotein-spezifische monoklonale antikörper des ebola-virus und deren verwendungen
|
TW202043253A
(zh)
|
2019-01-28 |
2020-12-01 |
美商安進公司 |
藉由將藥物物質和藥物產品過程整體化的生物製劑製造之連續製造過程
|
WO2020181140A1
(en)
|
2019-03-05 |
2020-09-10 |
Maverick Therapeutics, Inc. |
Constrained conditionally activated binding proteins
|
EP3962523A2
(de)
|
2019-05-03 |
2022-03-09 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Neutralisierende antikörper gegen das plasmodium-falciparum-circumsporozoit-protein und verwendung davon
|
JP7137696B2
(ja)
|
2019-05-14 |
2022-09-14 |
プロヴェンション・バイオ・インコーポレイテッド |
1型糖尿病を予防するための方法および組成物
|
KR20220008866A
(ko)
*
|
2019-05-14 |
2022-01-21 |
하푼 테라퓨틱스, 인크. |
EpCAM 결합 단백질 및 사용 방법
|
US20230085439A1
(en)
|
2019-05-21 |
2023-03-16 |
University Of Georgia Research Foundation, Inc. |
Antibodies that bind human metapneumovirus fusion protein and their use
|
US20220259329A1
(en)
|
2019-06-07 |
2022-08-18 |
Amgen Inc. |
Bispecific binding constructs
|
AU2020290573A1
(en)
|
2019-06-13 |
2021-11-04 |
Amgen Inc. |
Automated biomass-based perfusion control in the manufacturing of biologics
|
UY38748A
(es)
|
2019-06-14 |
2021-01-29 |
Teneobio Inc |
Anticuerpos multiespecíficos de cadena pesada que se unen a cd22 y cd3
|
EP3994173A1
(de)
|
2019-07-02 |
2022-05-11 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Monoklonale egfrviii-bindende antikörper und ihre verwendung
|
WO2021041300A2
(en)
*
|
2019-08-23 |
2021-03-04 |
Ab Therapeutics, Inc. |
Bispecific antibodies and uses thereof
|
AU2020345787A1
(en)
|
2019-09-10 |
2022-03-24 |
Amgen Inc. |
Purification method for bispecific antigen-binding polypeptides with enhanced protein L capture dynamic binding capacity
|
US20220389099A1
(en)
|
2019-11-04 |
2022-12-08 |
Amgen Inc. |
Methods for treating leukemia
|
EP3819312A1
(de)
|
2019-11-10 |
2021-05-12 |
Amgen, Inc |
Dosierschema für anti-dll3-wirkstoffe
|
EP3819007A1
(de)
|
2019-11-11 |
2021-05-12 |
Amgen Research (Munich) GmbH |
Dosierschema für anti-bcma-wirkstoffe
|
US20220396599A1
(en)
|
2019-11-13 |
2022-12-15 |
Amgen Inc. |
Method for Reduced Aggregate Formation in Downstream Processing of Bispecific Antigen-Binding Molecules
|
CA3164129A1
(en)
|
2019-12-20 |
2021-06-24 |
Amgen Inc. |
Mesothelin-targeted cd40 agonistic multispecific antibody constructs for the treatment of solid tumors
|
BR112022013725A2
(pt)
|
2020-01-13 |
2022-10-11 |
Aptevo Res & Development Llc |
Formulações para agentes terapêuticos proteicos
|
EP4090348A4
(de)
*
|
2020-01-13 |
2024-05-15 |
Univ California |
Verfahren zum behandeln von viralinfektionen
|
EP4090368A1
(de)
|
2020-01-13 |
2022-11-23 |
Aptevo Research and Development LLC |
Verfahren und zusammensetzungen zur verhinderung der adsorption therapeutischer proteine an komponenten eines wirkstoffabgabesystems
|
EP4093771A1
(de)
|
2020-01-22 |
2022-11-30 |
Amgen Research (Munich) GmbH |
Kombinationen von antikörperkonstrukten und inhibitoren des zytokinfreisetzungssyndroms und verwendungen davon
|
US20230071627A1
(en)
|
2020-02-03 |
2023-03-09 |
Amgen Inc. |
Multivariate Bracketing Approach for Sterile Filter Validation
|
WO2021183861A1
(en)
|
2020-03-12 |
2021-09-16 |
Amgen Inc. |
Method for treatment and prophylaxis of crs in patients comprising a combination of bispecifc antibodies binding to cds x cancer cell and tnfalpha or il-6 inhibitor
|
WO2021188851A1
(en)
|
2020-03-19 |
2021-09-23 |
Amgen Inc. |
Antibodies against mucin 17 and uses thereof
|
EP4186564A1
(de)
|
2020-04-29 |
2023-05-31 |
Teneoone, Inc. |
Multispezifische schwerkettige antikörper mit modifizierten schwerkettigen konstanten regionen
|
AU2021275049A1
(en)
|
2020-05-19 |
2022-12-22 |
Amgen Inc. |
MAGEB2 binding constructs
|
TW202210101A
(zh)
|
2020-05-29 |
2022-03-16 |
美商安進公司 |
與cd33和cd3結合的雙特異性構建體的減輕不良反應投與
|
AU2021283933A1
(en)
|
2020-06-04 |
2023-01-05 |
Amgen Inc. |
Bispecific binding constructs
|
AU2021340708A1
(en)
|
2020-09-11 |
2023-04-13 |
Amgen Inc. |
Materials and methods to reduce protein aggregation
|
CA3194771A1
(en)
|
2020-09-16 |
2022-03-24 |
Amgen Inc. |
Methods for administering therapeutic doses of bispecific t-cell engaging molecules for the treatment of cancer
|
WO2022060878A1
(en)
|
2020-09-16 |
2022-03-24 |
Amgen Inc. |
Methods for treating prostate cancer
|
US20220168407A1
(en)
|
2020-11-05 |
2022-06-02 |
Dcprime B.V. |
Use of tumor-independent antigens in immunotherapies
|
KR20230104256A
(ko)
|
2020-11-06 |
2023-07-07 |
암젠 인크 |
증가된 선택성의 다중표적화 이중특이적 항원 결합 분자
|
AU2021374036A1
(en)
|
2020-11-06 |
2023-06-08 |
Amgen Inc. |
Polypeptide constructs selectively binding to cldn6 and cd3
|
TW202233678A
(zh)
|
2020-11-06 |
2022-09-01 |
德商安美基研究(慕尼黑)公司 |
具有增強的剪切特徵的多肽
|
CA3199931A1
(en)
|
2020-11-06 |
2022-05-12 |
Amgen Inc. |
Polypeptide constructs binding to cd3
|
WO2022103781A1
(en)
|
2020-11-10 |
2022-05-19 |
Amgen Inc. |
Methods for administering a bcma x cd3 binding molecule
|
JP2023550148A
(ja)
|
2020-11-20 |
2023-11-30 |
シンシア・イノベーション・インコーポレイテッド |
がん免疫治療に用いられる武装二重car-t組成物及び方法
|
IL303205A
(en)
|
2020-12-03 |
2023-07-01 |
Amgen Inc |
IMMUNOGLOBULINE constructs with multiple binding domains
|
WO2022132904A1
(en)
|
2020-12-17 |
2022-06-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies targeting sars-cov-2
|
EP4291306A1
(de)
|
2021-02-09 |
2023-12-20 |
University of Georgia Research Foundation, Inc. |
Menschliche monoklonale antikörper gegen pneumokokken-antigene
|
EP4291226A1
(de)
|
2021-02-09 |
2023-12-20 |
The United States of America, as represented by the Secretary, Department of Health and Human Services |
Antikörper gegen das spike-protein von coronaviren
|
CA3208770A1
(en)
|
2021-03-10 |
2022-09-15 |
Amgen Inc. |
Parallel chromatography systems and methods
|
EP4305048A1
(de)
|
2021-03-10 |
2024-01-17 |
Amgen Inc. |
Verfahren zur reinigung rekombinanter proteine
|
CA3215594A1
(en)
|
2021-04-02 |
2022-10-06 |
Agnieszka KIELCZEWSKA |
Mageb2 binding constructs
|
CA3213632A1
(en)
|
2021-04-30 |
2022-11-03 |
F. Hoffmann-La Roche Ag |
Dosing for combination treatment with anti-cd20/anti-cd3 bispecific antibody and anti-cd79b antibody drug conjugate
|
TW202244059A
(zh)
|
2021-04-30 |
2022-11-16 |
瑞士商赫孚孟拉羅股份公司 |
用抗cd20/抗cd3雙特異性抗體進行治療之給藥
|
AU2022269312A1
(en)
|
2021-05-06 |
2023-10-19 |
Amgen Research (Munich) Gmbh |
Cd20 and cd22 targeting antigen-binding molecules for use in proliferative diseases
|
CN117651717A
(zh)
|
2021-05-18 |
2024-03-05 |
克里斯蒂安-阿尔伯特基尔大学 |
共刺激多特异性抗体
|
WO2022246244A1
(en)
|
2021-05-21 |
2022-11-24 |
Aptevo Research And Development Llc |
Dosing regimens for protein therapeutics
|
US11453723B1
(en)
|
2021-06-25 |
2022-09-27 |
Mcmaster University |
BCMA T cell-antigen couplers and uses thereof
|
WO2023044272A1
(en)
|
2021-09-17 |
2023-03-23 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Synthetic humanized llama nanobody library and use thereof to identify sars-cov-2 neutralizing antibodies
|
TW202326113A
(zh)
|
2021-10-27 |
2023-07-01 |
美商安進公司 |
使用光譜學進行的基於深度學習的預測
|
CA3237018A1
(en)
|
2021-11-03 |
2023-05-11 |
Joachim Koch |
Bispecific cd16a binders
|
CA3233696A1
(en)
|
2021-11-03 |
2023-05-11 |
Joachim Koch |
Bispecific cd16a binders
|
WO2023087255A1
(zh)
*
|
2021-11-19 |
2023-05-25 |
武汉友芝友生物制药股份有限公司 |
双特异性抗体及其应用
|
WO2023110918A1
(en)
|
2021-12-14 |
2023-06-22 |
Cdr-Life Ag |
Dual mhc-targeting t cell engager
|
WO2023154824A1
(en)
|
2022-02-10 |
2023-08-17 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Human monoclonal antibodies that broadly target coronaviruses
|
WO2023164474A1
(en)
|
2022-02-23 |
2023-08-31 |
Amgen Inc. |
Cancer treatment targeting dll3
|
US20230414750A1
(en)
|
2022-03-23 |
2023-12-28 |
Hoffmann-La Roche Inc. |
Combination treatment of an anti-cd20/anti-cd3 bispecific antibody and chemotherapy
|
WO2023192881A1
(en)
|
2022-03-28 |
2023-10-05 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to hiv-1 env and their use
|
WO2023198727A1
(en)
|
2022-04-13 |
2023-10-19 |
F. Hoffmann-La Roche Ag |
Pharmaceutical compositions of anti-cd20/anti-cd3 bispecific antibodies and methods of use
|
WO2023218027A1
(en)
|
2022-05-12 |
2023-11-16 |
Amgen Research (Munich) Gmbh |
Multichain multitargeting bispecific antigen-binding molecules of increased selectivity
|
WO2023230626A2
(en)
*
|
2022-05-27 |
2023-11-30 |
Bighat Biosciences, Inc. |
Ph-selective anti-cd3 antibodies and use of the same
|
WO2024030829A1
(en)
|
2022-08-01 |
2024-02-08 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Monoclonal antibodies that bind to the underside of influenza viral neuraminidase
|
WO2024054822A1
(en)
|
2022-09-07 |
2024-03-14 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Engineered sars-cov-2 antibodies with increased neutralization breadth
|
WO2024056758A1
(en)
|
2022-09-14 |
2024-03-21 |
Cdr-Life Ag |
Mage-a4 peptide dual t cell engagers
|
WO2024059675A2
(en)
|
2022-09-14 |
2024-03-21 |
Amgen Inc. |
Bispecific molecule stabilizing composition
|
WO2024064826A1
(en)
|
2022-09-22 |
2024-03-28 |
The United States Of America, As Represented By The Secretary, Department Of Health And Human Services |
Neutralizing antibodies to plasmodium falciparum circumsporozoite protein and their use
|
WO2024077044A1
(en)
|
2022-10-05 |
2024-04-11 |
Amgen Inc. |
Combination therapies comprising t-cell redirecting therapies and agonistic anti-il-2r antibodies or fragments thereof
|
WO2024082269A1
(zh)
*
|
2022-10-21 |
2024-04-25 |
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